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chlorpromazine and Atrophy

chlorpromazine has been researched along with Atrophy in 5 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.

Research Excerpts

ExcerptRelevanceReference
" Additional analysis revealed a significant positive correlation between baseline thalamic volume and dosage of typical antipsychotic medication."5.33Reduced thalamic volume in patients with chronic schizophrenia after switching from typical antipsychotic medications to olanzapine. ( Goghari, VM; Honer, WG; Khorram, B; Kopala, LC; Lang, DJ; Rui, Q; Smith, GN; Vandorpe, RA, 2006)
"Long-term (6 months) administration of 25 mg/kg body weight/day chlorpromazine (CPZ) to rats resulted in remarkable inhibition of normal increase with age of osmiophilic lipid droplets (OLD) in the pineal gland, and atrophy of pinealocytes."3.66Effects of long-term administration of chlorpromazine on the pineal gland of rats. ( Horita, N; Ishii, T; Moroji, T, 1978)
" Additional analysis revealed a significant positive correlation between baseline thalamic volume and dosage of typical antipsychotic medication."1.33Reduced thalamic volume in patients with chronic schizophrenia after switching from typical antipsychotic medications to olanzapine. ( Goghari, VM; Honer, WG; Khorram, B; Kopala, LC; Lang, DJ; Rui, Q; Smith, GN; Vandorpe, RA, 2006)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
FOLK, G1
Khorram, B1
Lang, DJ1
Kopala, LC1
Vandorpe, RA1
Rui, Q1
Goghari, VM1
Smith, GN1
Honer, WG1
Horita, N1
Ishii, T1
Moroji, T1
Feinberg, TE1
Cianci, CD1
Morrow, JS1
Pehta, JC1
Redman, CM1
Huima, T1
Koroshetz, WJ1
McLaughlin, RF1
Tyler, WS1
Edwards, DW1
Crenshaw, GL1
Canada, RO1
Fowler, MA1
Parker, EA1
Reifenstein, GH1

Other Studies

5 other studies available for chlorpromazine and Atrophy

ArticleYear
[Pathogenesis & propaphenine treatment of Sudeck's atrophy].
    Das Deutsche Gesundheitswesen, 1959, Mar-26, Volume: 14, Issue:13

    Topics: Atrophy; Chlorpromazine; Osteoporosis; Reflex Sympathetic Dystrophy

1959
Reduced thalamic volume in patients with chronic schizophrenia after switching from typical antipsychotic medications to olanzapine.
    The American journal of psychiatry, 2006, Volume: 163, Issue:11

    Topics: Adult; Antipsychotic Agents; Atrophy; Benzodiazepines; Chlorpromazine; Chronic Disease; Female; Foll

2006
Effects of long-term administration of chlorpromazine on the pineal gland of rats.
    Acta neuropathologica, 1978, Apr-26, Volume: 42, Issue:1

    Topics: Animals; Atrophy; Chlorpromazine; Lipids; Male; Pineal Gland; Rats; Time Factors

1978
Diagnostic tests for choreoacanthocytosis.
    Neurology, 1991, Volume: 41, Issue:7

    Topics: Acanthocytes; Atrophy; Blood Cells; Brain; Chlorpromazine; Chorea; Corpus Striatum; Edetic Acid; Fem

1991
Chlorpromazine-induced emphysema. Results of an initial study in the horse.
    The American review of respiratory disease, 1965, Volume: 92, Issue:4

    Topics: Animals; Atrophy; Bronchial Arteries; Bronchial Diseases; Chlorpromazine; Endarteritis; Horses; Inje

1965