chlorpromazine has been researched along with Atherosclerotic Parkinsonism in 55 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlorpromazine, a widely available and inexpensive antipsychotic drug, is considered the benchmark treatment for schizophrenia worldwide." | 8.95 | Chlorpromazine versus metiapine for schizophrenia. ( Bazrafshan, A; Zare, M, 2017) |
| "A Parkinsonian-like tremor can be induced by a combined application of chlorpromazine and pentobarbitone in cats." | 7.68 | Parkinsonian-like tremor induced by a combined application of chlorpromazine and pentobarbitone in cats with left-paw preference. ( Cankaya, A; Gepdiremen, A; Kutlu, N; Tan, U, 1992) |
| "Chlorpromazine, a widely available and inexpensive antipsychotic drug, is considered the benchmark treatment for schizophrenia worldwide." | 4.95 | Chlorpromazine versus metiapine for schizophrenia. ( Bazrafshan, A; Zare, M, 2017) |
| "A Parkinsonian-like tremor can be induced by a combined application of chlorpromazine and pentobarbitone in cats." | 3.68 | Parkinsonian-like tremor induced by a combined application of chlorpromazine and pentobarbitone in cats with left-paw preference. ( Cankaya, A; Gepdiremen, A; Kutlu, N; Tan, U, 1992) |
| "Pimozide was found to exert somewhat less of an overall therapeutic effect than chlorpromazine, particularly in highly agitated patients." | 2.65 | Pimozide in the treatment of newly admitted schizophrenic patients. ( Annable, L; Chouinard, G, 1982) |
| "Postural hypotension was observed in both patient groups." | 2.65 | Single daily dose chlorpromazine therapy in psychosis. An evaluation. ( Kalyanasundaram, S; Kapur, RL; Machado, TA; Shrikhande, SA, 1981) |
| " Improvement was recorded in a double blind study of 18 patients treated with maximum tolerated dosage (mean 18." | 2.64 | Tardive dyskinesia treated with pimozide. ( Calne, DB; Claveria, LE; Haskayne, L; Lodge-Patch, IC; Pallis, CA; Petrie, A; Teychenne, PF, 1975) |
| "Risperidone (4 mg/day) was added to her drug regimen and after increasing the dosage to 6 mg/day, she began to exhibit retrocollis." | 1.31 | Tardive dystonia provoked by concomitantly administered risperidone. ( Hori, M; Hori, T; Kawanishi, Y; Shiraishi, H; Suzuki, T; Tachikawa, H, 2000) |
| "Levodopa-induced dyskinesias (LID) in Parkinson's disease (PD) may be classified into three main categories: "On" dyskinesias, diphasic dyskinesias (DD), and "off" periods." | 1.28 | Levodopa-induced dyskinesias in Parkinson's disease: clinical and pharmacological classification. ( Gershanik, O; Luquin, MR; Obeso, JA; Scipioni, O; Vaamonde, J, 1992) |
| "A historical review of the adverse reactions to neuroleptic agents--extrapyramidal side effects--is presented." | 1.27 | Extrapyramidal side effects: a historical perspective. ( Rifkin, A, 1987) |
| "Tetrabenazine alone, was restarted after 48 hours to control her Huntington's Chorea and there was no recurrence of parkinsonism." | 1.27 | Iatrogenic parkinsonism in Huntington's chorea. ( Moss, JH; Stewart, DE, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 44 (80.00) | 18.7374 |
| 1990's | 5 (9.09) | 18.2507 |
| 2000's | 4 (7.27) | 29.6817 |
| 2010's | 1 (1.82) | 24.3611 |
| 2020's | 1 (1.82) | 2.80 |
| Authors | Studies |
|---|---|
| Olofinnade, AT | 1 |
| Onaolapo, TM | 1 |
| Oladimeji, S | 1 |
| Fatoki, AM | 1 |
| Balogun, CI | 1 |
| Onaolapo, AY | 1 |
| Onaolapo, OJ | 1 |
| Zare, M | 1 |
| Bazrafshan, A | 1 |
| Dean, CE | 1 |
| Kuskowski, MA | 1 |
| Caligiuri, MP | 1 |
| Costentin, J | 1 |
| Weiden, PJ | 1 |
| Sheppard, C | 1 |
| Merlis, S | 1 |
| Rubin, RT | 1 |
| Hays, SE | 1 |
| Ringwald, E | 1 |
| Lustig, A | 1 |
| Moscovici, M | 1 |
| Spiegel, R | 1 |
| Vamos, E | 1 |
| Bowers, MB | 3 |
| Heninger, GR | 1 |
| Rajput, AH | 1 |
| Rozdilsky, B | 1 |
| Hornykiewicz, O | 1 |
| Shannak, K | 1 |
| Lee, T | 1 |
| Seeman, P | 1 |
| Luchins, DJ | 1 |
| Jackman, H | 1 |
| Meltzer, HY | 1 |
| Hershey, LA | 1 |
| Gift, T | 1 |
| Atkins, RW | 1 |
| Rivera-Calimlim, L | 1 |
| Chouinard, G | 1 |
| Annable, L | 1 |
| Atadzhanov, M | 1 |
| Kalyanasundaram, S | 1 |
| Shrikhande, SA | 1 |
| Machado, TA | 1 |
| Kapur, RL | 1 |
| Tachikawa, H | 1 |
| Suzuki, T | 1 |
| Kawanishi, Y | 1 |
| Hori, M | 1 |
| Hori, T | 1 |
| Shiraishi, H | 1 |
| Vatsek, Ia | 1 |
| Kolakowska, T | 1 |
| Wiles, DH | 1 |
| Gelder, MG | 1 |
| McNeilly, AS | 1 |
| Claveria, LE | 1 |
| Teychenne, PF | 1 |
| Calne, DB | 1 |
| Haskayne, L | 1 |
| Petrie, A | 1 |
| Pallis, CA | 1 |
| Lodge-Patch, IC | 1 |
| Martin, IC | 1 |
| Tan, U | 1 |
| Gepdiremen, A | 1 |
| Kutlu, N | 1 |
| Cankaya, A | 1 |
| Sandyk, R | 1 |
| Kay, SR | 1 |
| Luquin, MR | 1 |
| Scipioni, O | 1 |
| Vaamonde, J | 1 |
| Gershanik, O | 1 |
| Obeso, JA | 1 |
| Keepers, GA | 1 |
| Casey, DE | 1 |
| Luo, S | 1 |
| Rao, JM | 1 |
| Cowie, VA | 1 |
| Mathew, B | 1 |
| Goswami, U | 1 |
| Dutta, S | 1 |
| Kuruvilla, K | 1 |
| Papp, E | 1 |
| Perenyi, A | 1 |
| Rifkin, A | 1 |
| Moss, JH | 1 |
| Stewart, DE | 1 |
| Kamianov, IM | 1 |
| Kupisk, AG | 1 |
| Katsen, IZ | 1 |
| Forrest, FM | 1 |
| Van Woert, MH | 2 |
| Sethy, VH | 1 |
| Ambani, LM | 2 |
| Steg, G | 1 |
| Carlsson, A | 1 |
| Bruck, H | 1 |
| Gerstenbrand, F | 1 |
| Gnad, H | 1 |
| Gründig, E | 1 |
| Prosenz, P | 1 |
| Klawans, HL | 1 |
| Bordeleau, JM | 1 |
| Tétreault, L | 1 |
| Kelly, JT | 1 |
| Zimmermann, RL | 1 |
| Abuzzahab, FS | 1 |
| Schiele, BC | 1 |
| Schulterbrandt, JG | 1 |
| Raskin, A | 1 |
| Reatig, N | 1 |
| Messiha, FS | 1 |
| Turek, I | 1 |
| De Maio, D | 1 |
| Morrison, AB | 1 |
| Webster, RA | 1 |
| Crane, GE | 1 |
| Maickel, RP | 1 |
| Braunstein, MC | 1 |
| McGlynn, M | 1 |
| Snodgrass, WR | 1 |
| Webb, RW | 1 |
| Kingstone, E | 1 |
| Kolivakis, T | 1 |
| Kossatz, I | 1 |
| O'Keeffe, R | 1 |
| Sharman, DF | 1 |
| Vogt, M | 1 |
| Demars, JP | 1 |
| Bruno, A | 1 |
| Bruno, SC | 1 |
| Zolotnitskii, RI | 1 |
| Kutsenok, BM | 1 |
| Gastev, MD | 1 |
| Ridges, AP | 1 |
| Harper, P | 1 |
| Dogliani, P | 1 |
| Senini, G | 1 |
| Bertuzzi, F | 1 |
| Oehme, P | 1 |
| Schwarz, K | 1 |
| Ekdawi, MY | 1 |
| Fowke, R | 1 |
7 reviews available for chlorpromazine and Atherosclerotic Parkinsonism
| Article | Year |
|---|---|
Chlorpromazine versus metiapine for schizophrenia.
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Dibenzothiazepines; Humans; Parkinson Disease, Secondar | 2017 |
The prolactin secretory response to neuroleptic drugs: mechanisms, applications and limitations.
Topics: Animals; Antipsychotic Agents; Blood-Brain Barrier; Cerebral Cortex; Chlorpromazine; Dopamine; Drug | 1980 |
[Modeling parkinsonism (review)].
Topics: Aluminum; Animals; Carbachol; Cats; Caudate Nucleus; Chlorides; Chlorpromazine; Disease Models, Anim | 1982 |
[Extrapyramidal movement disorders arising during treatment of psychoses with drugs].
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Chlorpromazine; Humans; Hyperkinesis; Movement Disorde | 1976 |
Pathological aspects on Parkinson's syndrome.
Topics: Animals; Basal Ganglia; Basal Ganglia Diseases; Central Nervous System; Chlorpromazine; Corpus Stria | 1972 |
Biochemical and pharmacological aspects of Parkinsonism.
Topics: Animals; Blood-Brain Barrier; Brain; Central Nervous System; Chemoreceptor Cells; Chlorpromazine; Co | 1972 |
The pharmacology of parkinsonism (a review).
Topics: Acetylcholine; Animals; Atropa belladonna; Atropine; Central Nervous System; Chlorpromazine; Dextroa | 1968 |
10 trials available for chlorpromazine and Atherosclerotic Parkinsonism
| Article | Year |
|---|---|
Pimozide in the treatment of newly admitted schizophrenic patients.
Topics: Acute Disease; Adult; Chlorpromazine; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Humans; | 1982 |
Single daily dose chlorpromazine therapy in psychosis. An evaluation.
Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Consciousness Disorders; Double-Blind M | 1981 |
Clinical significance of plasma chlorpromazine levels. II. Plasma levels of the drug, some of its metabolites and prolactin in patients receiving long-term phenothiazine treatment.
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Drug Tolerance; Female; Humans; Male; Middle Aged; Park | 1976 |
Tardive dyskinesia treated with pimozide.
Topics: Aged; Antipsychotic Agents; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Consciousnes | 1975 |
Implications of phenothiazine side effects: a study of antiparkinsonian agents in an older population.
Topics: Adult; Aged; Antipsychotic Agents; Chlorpromazine; Clinical Trials as Topic; Delayed-Action Preparat | 1975 |
A double-blind study of amantadine hydrochloride versus benztropine mesylate in drug-induced parkinsonism.
Topics: Administration, Oral; Amantadine; Antiparkinson Agents; Benztropine; Capsules; Chlorpromazine; Clini | 1974 |
True and apparent side effects in a controlled trial of chlorpromazine and imipramine in depression.
Topics: Adult; Agranulocytosis; Chlorpromazine; Clinical Trials as Topic; Depression; Dermatitis; Edema; Eva | 1974 |
Double blind study of clopenthixol and chlorpromazine in acute hospitalized schizophrenics.
Topics: Acute Disease; Adolescent; Adult; Aged; Aspartate Aminotransferases; Blood Pressure; Body Weight; Ch | 1970 |
Neuromuscular effects of long-term phenothiazine medication, electroconvulsive therapy and leucotomy.
Topics: Aged; Chlorpromazine; Clinical Trials as Topic; Electric Stimulation Therapy; Female; Haloperidol; H | 1966 |
Effects of L-DOPA on pharmacological parkinsonism.
Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Dihydroxyphenylalanine; Female; Haloper | 1966 |
38 other studies available for chlorpromazine and Atherosclerotic Parkinsonism
| Article | Year |
|---|---|
An Evaluation of the Effects of Pyridoxal Phosphate in Chlorpromazineinduced Parkinsonism using Mice.
Topics: Animals; Antioxidants; Antiparkinson Agents; Antipsychotic Agents; Behavior, Animal; Body Weight; Ca | 2020 |
Predictors of neuroleptic-induced dyskinesia and parkinsonism: the influence of measurement methods and definitions.
Topics: Adult; Age Distribution; Age Factors; Aged; Aging; Antipsychotic Agents; Chlorpromazine; Craniocereb | 2006 |
[Seeing a new classification of active medications in psychoses].
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Chlorpromazine; Dopamine D2 Receptor Antagonists; Huma | 2007 |
Antipsychotic-induced movement disorders - forgotten but not gone.
Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Brain; Chlorpromazine; Clozapine; Dopamine; Dyskinesi | 2008 |
Drug-induced extrapyramidal symptoms: their incidence and treatment.
Topics: Chlorpromazine; Chlorprothixene; Extrapyramidal Tracts; Female; Fluphenazine; Humans; Male; Parasymp | 1967 |
[Effect of high single doses of bromocriptine in schizophrenic patients with elevated serum prolactin levels and extrapyramidal side effects associated with neuroleptic treatment (author's transl)].
Topics: Adult; Antipsychotic Agents; Bromocriptine; Chlorpromazine; Chronic Disease; Dose-Response Relations | 1980 |
Cerebrospinal fluid homovanillic acid patterns during neuroleptic treatment.
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Female; Haloperidol; Homovanillic Acid; Humans; Male; P | 1981 |
Reversible drug-induced parkinsonism. Clinicopathologic study of two cases.
Topics: Aged; Antipsychotic Agents; Chlorpromazine; Haloperidol; Humans; Male; Middle Aged; Parkinson Diseas | 1982 |
Lateral ventricular size and drug-induced Parkinsonism.
Topics: Adolescent; Adult; Antiparkinson Agents; Cerebral Ventricles; Chlorpromazine; Female; Humans; Male; | 1983 |
Effect of a drug holiday on plasma chlorpromazine levels in chronic schizophrenic patients.
Topics: Adult; Chlorpromazine; Chronic Disease; Humans; Male; Middle Aged; Parkinson Disease, Secondary; Phe | 1981 |
Tardive dystonia provoked by concomitantly administered risperidone.
Topics: Adolescent; Antipsychotic Agents; Chlorpromazine; Drug Therapy, Combination; Dyskinesia, Drug-Induce | 2000 |
Parkinsonian-like tremor induced by a combined application of chlorpromazine and pentobarbitone in cats with left-paw preference.
Topics: Animals; Atropine; Baclofen; Biperiden; Cats; Chlorpromazine; Feedback; Female; Functional Lateralit | 1992 |
"Positive" and "negative" movement disorders in schizophrenia.
Topics: Adult; Chlorpromazine; Dyskinesia, Drug-Induced; Female; Humans; Male; Parkinson Disease, Secondary; | 1992 |
Levodopa-induced dyskinesias in Parkinson's disease: clinical and pharmacological classification.
Topics: Aged; Apomorphine; Chlorpromazine; Dopamine Agents; Dose-Response Relationship, Drug; Dyskinesia, Dr | 1992 |
Use of neuroleptic-induced extrapyramidal symptoms to predict future vulnerability to side effects.
Topics: Adult; Age Factors; Antipsychotic Agents; Basal Ganglia Diseases; Benztropine; Chlorpromazine; Disea | 1991 |
[A control study of some hair trace elements content of schizophrenics before and after treatment].
Topics: Adolescent; Adult; Chlorpromazine; Female; Hair; Humans; Male; Middle Aged; Parkinson Disease, Secon | 1991 |
Neuroleptic-induced parkinsonian side effects in the mentally handicapped.
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Dyskinesia, Drug-Induced; Female; Humans; Intellectual | 1989 |
Electroconvulsive therapy in neuroleptic-induced parkinsonism.
Topics: Adolescent; Adult; Antipsychotic Agents; Chlorpromazine; Dose-Response Relationship, Drug; Electroco | 1989 |
Cerebrospinal fluid homovanillic acid and hypokinetic side effects of neuroleptics.
Topics: Acetylcholine; Adolescent; Adult; Antipsychotic Agents; Catatonia; Chlorpromazine; Dopamine; Female; | 1985 |
Extrapyramidal side effects: a historical perspective.
Topics: Adult; Antipsychotic Agents; Attitude to Health; Basal Ganglia Diseases; Chlorpromazine; Depressive | 1987 |
Iatrogenic parkinsonism in Huntington's chorea.
Topics: Chlorpromazine; Drug Interactions; Female; Humans; Huntington Disease; Middle Aged; Parkinson Diseas | 1986 |
[Experience with the use of midantan for treatment and prevention of the neuroleptic syndrome].
Topics: Adult; Amantadine; Antiparkinson Agents; Antipsychotic Agents; Catatonia; Chlorpromazine; Facial Mus | 1973 |
Evolutionary origin of extrapyramidal disorders in drug-treated mental patients, its significance, and the role of neuromelanin.
Topics: Amphibians; Animals; Antipsychotic Agents; Basal Ganglia Diseases; Biological Evolution; Chlorpromaz | 1974 |
Effect of phenothiazines on central cholinergic activity.
Topics: Acetylcholine; Animals; Antipsychotic Agents; Basal Ganglia Diseases; Brain; Brain Chemistry; Chlorp | 1974 |
[Comparative biochemical studies in organic parkinsonian syndromes and drug induced parkinsonian syndromes].
Topics: Alanine Transaminase; Aspartate Aminotransferases; Biochemical Phenomena; Biochemistry; Chlorpromazi | 1966 |
[Study of extrapyramidal manifestations induced by neuroleptics].
Topics: Antiparkinson Agents; Chlorpromazine; Drug Synergism; Extrapyramidal Tracts; Fluphenazine; Haloperid | 1972 |
Decreased dopamine and homovanillic acid excretion in a case with chlorpromazine-induced Parkinsonism.
Topics: Chlorpromazine; Dopamine; Homovanillic Acid; Humans; Male; Parkinson Disease; Parkinson Disease, Sec | 1973 |
Letter: Withdrawal syndrome after neuroleptics.
Topics: Adult; Chlorpromazine; Haloperidol; Humans; Male; Parkinson Disease, Secondary; Substance Withdrawal | 1973 |
Drug-induced experimental Parkinsonism.
Topics: Animals; Atropine; Benztropine; Butyrophenones; Cats; Chlorpromazine; Dose-Response Relationship, Dr | 1973 |
Physostigmine effects on phenothiazine-induced extrapyramidal reactions.
Topics: Adult; Antiparkinson Agents; Chlorpromazine; Drug Hypersensitivity; Extrapyramidal Tracts; Female; H | 1973 |
Factors predisposing to drug-induced neurologic effects.
Topics: Age Factors; Antiparkinson Agents; Central Nervous System Diseases; Chlorpromazine; Chronic Disease; | 1974 |
Behavioral, biochemical, and pharmacological effects of chronic dosage of phenothiazine tranquilizers in rats.
Topics: Animals; Avoidance Learning; Behavior, Animal; Body Weight; Brain Chemistry; Chlorpromazine; Dose-Re | 1974 |
Effect of drugs used in psychoses on cerebral dopamine metabolism.
Topics: Animals; Atropine; Brain; Butyrophenones; Cats; Chlorpromazine; Dogs; Dopamine; Female; Haloperidol; | 1970 |
[On the results of treatment and complications during the use of haloperidol in patients with long-term schizophrenia].
Topics: Adult; Blood Pressure; Cardiovascular Diseases; Catatonia; Chlorpromazine; Cognition Disorders; Hall | 1969 |
Pink spot--is it a drug artefact?
Topics: Amitriptyline; Amobarbital; Chlorpromazine; Chromatography; Haloperidol; Humans; Mental Disorders; P | 1970 |
Clinical observations on the therapeutic activity of flupentixol in the treatment of chronic schizophrenia.
Topics: Adult; Aged; Blood; Body Weight; Chlorpromazine; Chronic Disease; Delusions; Depression, Chemical; F | 1970 |
[Etiology and therapy of Parkinson's syndrome and related pharmacological concepts shown in experimental models].
Topics: Animals; Brain Chemistry; Chlorpromazine; Dihydroxyphenylalanine; Dopamine; Humans; Hypothermia; Mic | 1966 |
A controlled trial of anti-Parkinson drugs in drug-induced Parkinsonism.
Topics: Adolescent; Adult; Chlorpromazine; Haloperidol; Humans; Middle Aged; Orphenadrine; Parasympatholytic | 1966 |