chlorpromazine has been researched along with Arrhythmias, Cardiac in 40 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the mechanism of chlorpromazine(CPZ)-induced ventricular arrhythmia, the changes in ventricular fibrillation threshold (VFT) were followed after intravenous injection of CPZ (1 mg/Kg) in dogs." | 7.66 | Protection of chlorpromazine-induced arrhythmia by flavin-adenine-dinucleotide in canine heart. ( Ozawa, T; Sugiyama, S, 1979) |
| "No protection against drug-induced arrhythmia or death was afforded by this procedure." | 5.27 | Does chlorpromazine produce cardiac arrhythmia via the central nervous system? ( Lathers, CM; Lipka, LJ; Roberts, J, 1988) |
| "The incidence of arrhythmias increased with the concentration of noradrenaline applied and the dose of tricyclic drug administered." | 5.25 | Arrhythmias and inhibition of noradrenaline uptake caused by tricyclic antidepressants and chlorpromazine on the isolated perfused rabbit heart. ( Barth, N; Manns, M; Muscholl, E, 1975) |
| "To determine the effect of chlorpromazine on ouabain-induced arrhythmia and death, dial-urethane anesthetized cats were pretreated with chlorpromazine (5, 10, 20, 30, 40, or 60 mg/kg, i." | 3.67 | Chlorpromazine: cardiac arrhythmogenicity in the cat. ( Lathers, CM; Lipka, LJ, 1986) |
| "To investigate the mechanism of chlorpromazine(CPZ)-induced ventricular arrhythmia, the changes in ventricular fibrillation threshold (VFT) were followed after intravenous injection of CPZ (1 mg/Kg) in dogs." | 3.66 | Protection of chlorpromazine-induced arrhythmia by flavin-adenine-dinucleotide in canine heart. ( Ozawa, T; Sugiyama, S, 1979) |
| " The ventricular arrhythmias responded to intravenous administration of lidocaine and to direct current electric shock; ventricular pacing was required in some instances and intravenous administration of propranolol combined with ventricular pacing in one." | 3.65 | Electrocardiographic changes and cardiac arrhythmias in patients receiving psychotropic drugs. ( Chou, TC; Fowler, NO; Hanenson, IB; Holmes, JC; McCall, D, 1976) |
| "No protection against drug-induced arrhythmia or death was afforded by this procedure." | 1.27 | Does chlorpromazine produce cardiac arrhythmia via the central nervous system? ( Lathers, CM; Lipka, LJ; Roberts, J, 1988) |
| " The adverse effects of MPC were studied prospectively in 95 patients undergoing various procedures." | 1.27 | Adverse effects of meperidine, promethazine, and chlorpromazine for sedation in pediatric patients. ( Clotz, MA; Krogg, EA; Nahata, MC, 1985) |
| " After the drug injection, however, the duration increased significantly with increasing heart rate, the effect depending on the injected dosage (r==0." | 1.26 | The prolongation of QRS-duration resulting from delayed recovery of ventricular excitability. A new mechanism for intraventricular conduction disturbance. A preliminary note. ( Arita, M; Nagamoto, Y; Saikawa, T, 1976) |
| "The incidence of arrhythmias increased with the concentration of noradrenaline applied and the dose of tricyclic drug administered." | 1.25 | Arrhythmias and inhibition of noradrenaline uptake caused by tricyclic antidepressants and chlorpromazine on the isolated perfused rabbit heart. ( Barth, N; Manns, M; Muscholl, E, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (87.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (2.50) | 29.6817 |
| 2010's | 3 (7.50) | 24.3611 |
| 2020's | 1 (2.50) | 2.80 |
| Authors | Studies |
|---|---|
| Jia, L | 1 |
| Sun, H | 1 |
| Vivier, D | 1 |
| Bennis, K | 1 |
| Lesage, F | 1 |
| Ducki, S | 1 |
| Choi, M | 1 |
| Barra, ME | 1 |
| Newman, K | 1 |
| Sin, JH | 1 |
| Gioia, S | 1 |
| Lancia, M | 1 |
| Bacci, M | 1 |
| Suadoni, F | 1 |
| Kuruvilla, R | 1 |
| Sahu, PD | 1 |
| Meltzer, MA | 1 |
| WEINBERG, SJ | 1 |
| HALEY, TJ | 1 |
| ARORA, RB | 1 |
| MADAN, BR | 1 |
| HUANG, TF | 1 |
| SATO, T | 1 |
| TANABE, Y | 1 |
| MAEKAWA, M | 1 |
| NOHARA, Y | 1 |
| BURIAK, MA | 1 |
| BAECKMAN, H | 1 |
| ELOSUO, R | 1 |
| BEAULNES, A | 1 |
| LAVALLEE, M | 1 |
| Risch, SC | 1 |
| Groom, GP | 1 |
| Janowsky, DS | 1 |
| Kitazawa, M | 1 |
| Sugiyama, S | 2 |
| Ozawa, T | 2 |
| Miyazaki, Y | 1 |
| Kotaka, K | 1 |
| Menes, C | 1 |
| Burra, P | 1 |
| Hoaken, PC | 1 |
| Elkayam, U | 1 |
| Frishman, W | 1 |
| Fowler, NO | 1 |
| McCall, D | 1 |
| Chou, TC | 1 |
| Holmes, JC | 1 |
| Hanenson, IB | 1 |
| Guillan, RA | 2 |
| Yang, C | 1 |
| Wilson, SS | 1 |
| Hocker, EV | 1 |
| Nagamoto, Y | 2 |
| Arita, M | 2 |
| Saikawa, T | 2 |
| Barth, N | 1 |
| Manns, M | 1 |
| Muscholl, E | 1 |
| Lipka, LJ | 2 |
| Lathers, CM | 2 |
| Roberts, J | 1 |
| Nicolai, B | 1 |
| Raabe, A | 1 |
| Fleischmann, HJ | 1 |
| Albrecht, M | 1 |
| Nahata, MC | 1 |
| Clotz, MA | 1 |
| Krogg, EA | 1 |
| Prys-Roberts, C | 1 |
| Corbett, JL | 1 |
| Kerr, JH | 1 |
| Smith, AC | 1 |
| Spalding, JM | 1 |
| Lerner, EM | 1 |
| Lapitsky, MA | 1 |
| Fidler, MG | 1 |
| Douglas, JE | 1 |
| Pieschl, D | 1 |
| Santos-Martinez, J | 1 |
| Laboy-Torres, JA | 1 |
| Aviles, TA | 1 |
| Lopez, JE | 1 |
| Stein, H | 1 |
| Rubin, S | 1 |
| Merin, G | 1 |
| Cotev, S | 1 |
| Borman, JB | 1 |
| Shamsi, MA | 1 |
| Kulshrestha, VK | 1 |
| Dhawan, KN | 1 |
| Bhargava, KP | 1 |
| Bingham, W | 1 |
| Elliott, J | 1 |
| Lyons, SM | 1 |
| Smalley, RL | 1 |
| Zelman, S | 1 |
| McDowall, DG | 1 |
| Buryak, MA | 1 |
| Lehr, E | 1 |
| Werner, G | 1 |
| Haller, JA | 1 |
| Crisler, C | 1 |
| Brawley, R | 1 |
| Cameron, J | 1 |
| Rowe, RD | 1 |
4 reviews available for chlorpromazine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Struc | 2016 |
Interfaces of psychopharmacology and cardiology--Part two.
Topics: Adrenergic alpha-Antagonists; Anti-Anxiety Agents; Antipsychotic Agents; Arrhythmias, Cardiac; Auton | 1981 |
Cardiovascular effects of phenothiazines.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Cardiopulmonary Bypass; Cardi | 1980 |
[The cardiovascular effects of neuroleptics based on current knowledge].
Topics: Adolescent; Adult; Aged; Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Blood Pressure; Ca | 1973 |
36 other studies available for chlorpromazine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant | 2008 |
Safety and Effectiveness of Intravenous Chlorpromazine for Agitation in Critically Ill Patients.
Topics: Administration, Intravenous; Adult; Aged; Antipsychotic Agents; Arrhythmias, Cardiac; Blood Pressure | 2020 |
A Fatal Case of Acute Butane-Propane Poisoning in a Prisoner Under Psychiatric Treatment: Do These 2 Factors Have an Arrhythmogenic Interaction, Thus Increasing the Cardiovascular Risk Profile?
Topics: Adult; Antipsychotic Agents; Arrhythmias, Cardiac; Butanes; Chlorpromazine; Citalopram; Drug Interac | 2015 |
Systemic uptake of chlorpromazine after delivery via retrobulbar injection.
Topics: Antipsychotic Agents; Arrhythmias, Cardiac; Chlorpromazine; Dizziness; Electrocardiography; Eye Pain | 2012 |
Effect of chlorpromazine on cardiac arrhythmias induced by intra-cerebral injection of tryptaminestrophanthidin.
Topics: Arrhythmias, Cardiac; Chlorpromazine; Strophanthins; Tyramine | 1956 |
Chlorpromazine in experimental cardiac arrhythmias.
Topics: Arrhythmias, Cardiac; Chlorpromazine; Humans | 1956 |
Studies on prevention and abolition of fibrillation of the cat's heart by drugs.
Topics: Animals; Arrhythmias, Cardiac; Atrial Fibrillation; Brugada Syndrome; Cardiac Conduction System Dise | 1963 |
The antiarrhythmic action of phenothiazine derivatives.
Topics: Anti-Arrhythmia Agents; Antipsychotic Agents; Arrhythmias, Cardiac; Chlorpromazine; Phenothiazines; | 1962 |
[DRUGS FOR TREATING ARRHYTHMIA].
Topics: Arrhythmias, Cardiac; Chlorpromazine; Digitalis Glycosides; Humans; Pharmacology; Potassium; Procain | 1963 |
[EFFECT OF AMINAZIN ON EXPERIMENTAL ARRHYTHMIA OF CENTRAL ORIGIN].
Topics: Arrhythmias, Cardiac; Brain; Cats; Cerebral Ventricles; Chlorpromazine; Electric Stimulation; Electr | 1964 |
ELECTROCARDIOGRAPHIC FINDINGS IN CONNECTION WITH A CLINICAL TRIAL OF CHLORPROMAZINE. WITH PARTICULAR REFERENCE TO T WAVE CHANGES AND THE DURATION OF VENTRICULAR ACTIVITY.
Topics: Arrhythmias, Cardiac; Biomedical Research; Chlorpromazine; Electrocardiography; Heart Conduction Sys | 1964 |
DIFFERENTIAL EFFECTS OF SOME PHENOTHIAZINE DERIVATIVES AGAINST CALCIUM-INDUCED VENTRICULAR ARRHYTHMIAS IN THE ISOLATED RABBIT HEART.
Topics: Antipsychotic Agents; Arrhythmias, Cardiac; Brugada Syndrome; Calcium; Calcium Chloride; Cardiac Con | 1964 |
Mechanism of chlorpromazine-induced arrhythmia -- arrhythmia and mitochondrial dysfunction.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cardiac Complexes, Premature; Chlorpromazine; Coenzym | 1981 |
Untoward effects following combined neuroleptic-lithium therapy. Cardiac arrhythmias and seizure.
Topics: Adult; Arrhythmias, Cardiac; Bipolar Disorder; Chlorpromazine; Drug Therapy, Combination; Epilepsy, | 1980 |
Electrocardiographic changes and cardiac arrhythmias in patients receiving psychotropic drugs.
Topics: Adrenergic Agonists; Adult; Aged; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Cardiovasc | 1976 |
Protection of chlorpromazine-induced arrhythmia by flavin-adenine-dinucleotide in canine heart.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Chlorpromazine; Dogs; Flavin-Adenine Dinucleotide; Mi | 1979 |
Phenothiazine cardiomyopathy: electrolyte alterations in serum and cardiac tissue of rabbits with acute thorazine intoxication.
Topics: Animals; Arrhythmias, Cardiac; Chlorpromazine; Electrolytes; Female; Heart Diseases; Male; Myocardiu | 1977 |
The prolongation of QRS-duration resulting from delayed recovery of ventricular excitability. A new mechanism for intraventricular conduction disturbance. A preliminary note.
Topics: Animals; Arrhythmias, Cardiac; Chlorpromazine; Disease Models, Animal; Dogs; Electrocardiography; He | 1976 |
Automaticity and time-dependent conduction disturbance produced in canine ventricular myocardium. New aspects for initiation of ventricular arrhythmias.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Chlorpromazine; Depression, Chemical; Dogs; Heart | 1976 |
Arrhythmias and inhibition of noradrenaline uptake caused by tricyclic antidepressants and chlorpromazine on the isolated perfused rabbit heart.
Topics: Animals; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Chlorpromazine; Cocaine; Coronary C | 1975 |
Does chlorpromazine produce cardiac arrhythmia via the central nervous system?
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Central Nervous System; Chlorpromazine; Decereb | 1988 |
[Long-term ECG control in gastroscopies using Obsidan and Elroquil premedication].
Topics: Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Chlorpromazine; Electrocardiography; Female; G | 1987 |
Chlorpromazine: cardiac arrhythmogenicity in the cat.
Topics: Adrenal Glands; Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Chlorpromazine; Dose-Response R | 1986 |
Adverse effects of meperidine, promethazine, and chlorpromazine for sedation in pediatric patients.
Topics: Adolescent; Arrhythmias, Cardiac; Biopsy; Blood Pressure; Cardiac Catheterization; Child, Preschool; | 1985 |
Treatment of sympathetic overactivity in tetanus.
Topics: Adult; Aged; Anesthesia, General; Arrhythmias, Cardiac; Blood Pressure; Cardiovascular Diseases; Chi | 1969 |
Concerning the influence of non-specific brain-stem structures on the vegetative functions of the brain in cerebral pathology.
Topics: Animals; Arrhythmias, Cardiac; Body Temperature; Cats; Chlorpromazine; Electroencephalography; Hemat | 1969 |
Electrocardiogram of the month.
Topics: Arrhythmias, Cardiac; Chlorpromazine; Electrocardiography; Female; Heart Rate; Humans; Middle Aged; | 1972 |
Electrocardiographic changes induced by some phenothiazine derivatives.
Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Atropine; Chlorpromazine; Dogs; Electrocardiography; Pota | 1973 |
Successful prolonged resuscitation after open heart surgery.
Topics: Adult; Arrhythmias, Cardiac; Atrial Fibrillation; Blood Gas Analysis; Blood Pressure; Bradycardia; B | 1971 |
Correlation of chemical structure of phenothiazines with their coronary dilator and antiarrhythmic activities.
Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chlorpromazine; Coronary Vessels; | 1971 |
Management of anaesthesia for phaeochromocytoma.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Anesthesia, General; Arrhythmias, Cardiac; Blood Pressur | 1972 |
Electrocardiographic and ultrastructural cardiac effects of phenothiazine in rabbits: a preliminary report.
Topics: Animals; Arrhythmias, Cardiac; Aspartate Aminotransferases; Chlorpromazine; Creatine Kinase; Electro | 1972 |
The current usage of hypothermia in British neurosurgery.
Topics: Anesthesia, General; Arrhythmias, Cardiac; Blood Pressure; Body Temperature; Central Venous Pressure | 1971 |
The influence of neurotropic drugs on experimental arrhythmia evoked by local stimulation of the bulbar reticular formation.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Brain Stem; Cats; Chlorpromazine; Electric Stimulatio | 1967 |
[Mescaline induced bradycardia and its antagonistic modification by chlorpromazine, pentobarbital and scopolamine after injection into lateral cerebral ventricle of mouse].
Topics: Animals; Arrhythmias, Cardiac; Bradycardia; Cerebral Ventricles; Chlorpromazine; Depression, Chemica | 1970 |
Operative correction and postoperative management of transposition of the great vessels in nine children.
Topics: Arrhythmias, Cardiac; Blood Pressure; Blood Volume; Child; Child, Preschool; Chlorpromazine; Humans; | 1969 |