chlorpromazine has been researched along with Arrhythmia in 40 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the mechanism of chlorpromazine(CPZ)-induced ventricular arrhythmia, the changes in ventricular fibrillation threshold (VFT) were followed after intravenous injection of CPZ (1 mg/Kg) in dogs." | 7.66 | Protection of chlorpromazine-induced arrhythmia by flavin-adenine-dinucleotide in canine heart. ( Ozawa, T; Sugiyama, S, 1979) |
| "No protection against drug-induced arrhythmia or death was afforded by this procedure." | 5.27 | Does chlorpromazine produce cardiac arrhythmia via the central nervous system? ( Lathers, CM; Lipka, LJ; Roberts, J, 1988) |
| "The incidence of arrhythmias increased with the concentration of noradrenaline applied and the dose of tricyclic drug administered." | 5.25 | Arrhythmias and inhibition of noradrenaline uptake caused by tricyclic antidepressants and chlorpromazine on the isolated perfused rabbit heart. ( Barth, N; Manns, M; Muscholl, E, 1975) |
| "To determine the effect of chlorpromazine on ouabain-induced arrhythmia and death, dial-urethane anesthetized cats were pretreated with chlorpromazine (5, 10, 20, 30, 40, or 60 mg/kg, i." | 3.67 | Chlorpromazine: cardiac arrhythmogenicity in the cat. ( Lathers, CM; Lipka, LJ, 1986) |
| "To investigate the mechanism of chlorpromazine(CPZ)-induced ventricular arrhythmia, the changes in ventricular fibrillation threshold (VFT) were followed after intravenous injection of CPZ (1 mg/Kg) in dogs." | 3.66 | Protection of chlorpromazine-induced arrhythmia by flavin-adenine-dinucleotide in canine heart. ( Ozawa, T; Sugiyama, S, 1979) |
| " The ventricular arrhythmias responded to intravenous administration of lidocaine and to direct current electric shock; ventricular pacing was required in some instances and intravenous administration of propranolol combined with ventricular pacing in one." | 3.65 | Electrocardiographic changes and cardiac arrhythmias in patients receiving psychotropic drugs. ( Chou, TC; Fowler, NO; Hanenson, IB; Holmes, JC; McCall, D, 1976) |
| "No protection against drug-induced arrhythmia or death was afforded by this procedure." | 1.27 | Does chlorpromazine produce cardiac arrhythmia via the central nervous system? ( Lathers, CM; Lipka, LJ; Roberts, J, 1988) |
| " The adverse effects of MPC were studied prospectively in 95 patients undergoing various procedures." | 1.27 | Adverse effects of meperidine, promethazine, and chlorpromazine for sedation in pediatric patients. ( Clotz, MA; Krogg, EA; Nahata, MC, 1985) |
| " After the drug injection, however, the duration increased significantly with increasing heart rate, the effect depending on the injected dosage (r==0." | 1.26 | The prolongation of QRS-duration resulting from delayed recovery of ventricular excitability. A new mechanism for intraventricular conduction disturbance. A preliminary note. ( Arita, M; Nagamoto, Y; Saikawa, T, 1976) |
| "The incidence of arrhythmias increased with the concentration of noradrenaline applied and the dose of tricyclic drug administered." | 1.25 | Arrhythmias and inhibition of noradrenaline uptake caused by tricyclic antidepressants and chlorpromazine on the isolated perfused rabbit heart. ( Barth, N; Manns, M; Muscholl, E, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (87.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (2.50) | 29.6817 |
| 2010's | 3 (7.50) | 24.3611 |
| 2020's | 1 (2.50) | 2.80 |
| Authors | Studies |
|---|---|
| Jia, L | 1 |
| Sun, H | 1 |
| Vivier, D | 1 |
| Bennis, K | 1 |
| Lesage, F | 1 |
| Ducki, S | 1 |
| Choi, M | 1 |
| Barra, ME | 1 |
| Newman, K | 1 |
| Sin, JH | 1 |
| Gioia, S | 1 |
| Lancia, M | 1 |
| Bacci, M | 1 |
| Suadoni, F | 1 |
| Kuruvilla, R | 1 |
| Sahu, PD | 1 |
| Meltzer, MA | 1 |
| WEINBERG, SJ | 1 |
| HALEY, TJ | 1 |
| ARORA, RB | 1 |
| MADAN, BR | 1 |
| HUANG, TF | 1 |
| SATO, T | 1 |
| TANABE, Y | 1 |
| MAEKAWA, M | 1 |
| NOHARA, Y | 1 |
| BURIAK, MA | 1 |
| BAECKMAN, H | 1 |
| ELOSUO, R | 1 |
| BEAULNES, A | 1 |
| LAVALLEE, M | 1 |
| Risch, SC | 1 |
| Groom, GP | 1 |
| Janowsky, DS | 1 |
| Kitazawa, M | 1 |
| Sugiyama, S | 2 |
| Ozawa, T | 2 |
| Miyazaki, Y | 1 |
| Kotaka, K | 1 |
| Menes, C | 1 |
| Burra, P | 1 |
| Hoaken, PC | 1 |
| Elkayam, U | 1 |
| Frishman, W | 1 |
| Fowler, NO | 1 |
| McCall, D | 1 |
| Chou, TC | 1 |
| Holmes, JC | 1 |
| Hanenson, IB | 1 |
| Guillan, RA | 2 |
| Yang, C | 1 |
| Wilson, SS | 1 |
| Hocker, EV | 1 |
| Nagamoto, Y | 2 |
| Arita, M | 2 |
| Saikawa, T | 2 |
| Barth, N | 1 |
| Manns, M | 1 |
| Muscholl, E | 1 |
| Lipka, LJ | 2 |
| Lathers, CM | 2 |
| Roberts, J | 1 |
| Nicolai, B | 1 |
| Raabe, A | 1 |
| Fleischmann, HJ | 1 |
| Albrecht, M | 1 |
| Nahata, MC | 1 |
| Clotz, MA | 1 |
| Krogg, EA | 1 |
| Prys-Roberts, C | 1 |
| Corbett, JL | 1 |
| Kerr, JH | 1 |
| Smith, AC | 1 |
| Spalding, JM | 1 |
| Lerner, EM | 1 |
| Lapitsky, MA | 1 |
| Fidler, MG | 1 |
| Douglas, JE | 1 |
| Pieschl, D | 1 |
| Santos-Martinez, J | 1 |
| Laboy-Torres, JA | 1 |
| Aviles, TA | 1 |
| Lopez, JE | 1 |
| Stein, H | 1 |
| Rubin, S | 1 |
| Merin, G | 1 |
| Cotev, S | 1 |
| Borman, JB | 1 |
| Shamsi, MA | 1 |
| Kulshrestha, VK | 1 |
| Dhawan, KN | 1 |
| Bhargava, KP | 1 |
| Bingham, W | 1 |
| Elliott, J | 1 |
| Lyons, SM | 1 |
| Smalley, RL | 1 |
| Zelman, S | 1 |
| McDowall, DG | 1 |
| Buryak, MA | 1 |
| Lehr, E | 1 |
| Werner, G | 1 |
| Haller, JA | 1 |
| Crisler, C | 1 |
| Brawley, R | 1 |
| Cameron, J | 1 |
| Rowe, RD | 1 |
4 reviews available for chlorpromazine and Arrhythmia
| Article | Year |
|---|---|
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Struc | 2016 |
Interfaces of psychopharmacology and cardiology--Part two.
Topics: Adrenergic alpha-Antagonists; Anti-Anxiety Agents; Antipsychotic Agents; Arrhythmias, Cardiac; Auton | 1981 |
Cardiovascular effects of phenothiazines.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Cardiopulmonary Bypass; Cardi | 1980 |
[The cardiovascular effects of neuroleptics based on current knowledge].
Topics: Adolescent; Adult; Aged; Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Blood Pressure; Ca | 1973 |
36 other studies available for chlorpromazine and Arrhythmia
| Article | Year |
|---|---|
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant | 2008 |
Safety and Effectiveness of Intravenous Chlorpromazine for Agitation in Critically Ill Patients.
Topics: Administration, Intravenous; Adult; Aged; Antipsychotic Agents; Arrhythmias, Cardiac; Blood Pressure | 2020 |
A Fatal Case of Acute Butane-Propane Poisoning in a Prisoner Under Psychiatric Treatment: Do These 2 Factors Have an Arrhythmogenic Interaction, Thus Increasing the Cardiovascular Risk Profile?
Topics: Adult; Antipsychotic Agents; Arrhythmias, Cardiac; Butanes; Chlorpromazine; Citalopram; Drug Interac | 2015 |
Systemic uptake of chlorpromazine after delivery via retrobulbar injection.
Topics: Antipsychotic Agents; Arrhythmias, Cardiac; Chlorpromazine; Dizziness; Electrocardiography; Eye Pain | 2012 |
Effect of chlorpromazine on cardiac arrhythmias induced by intra-cerebral injection of tryptaminestrophanthidin.
Topics: Arrhythmias, Cardiac; Chlorpromazine; Strophanthins; Tyramine | 1956 |
Chlorpromazine in experimental cardiac arrhythmias.
Topics: Arrhythmias, Cardiac; Chlorpromazine; Humans | 1956 |
Studies on prevention and abolition of fibrillation of the cat's heart by drugs.
Topics: Animals; Arrhythmias, Cardiac; Atrial Fibrillation; Brugada Syndrome; Cardiac Conduction System Dise | 1963 |
The antiarrhythmic action of phenothiazine derivatives.
Topics: Anti-Arrhythmia Agents; Antipsychotic Agents; Arrhythmias, Cardiac; Chlorpromazine; Phenothiazines; | 1962 |
[DRUGS FOR TREATING ARRHYTHMIA].
Topics: Arrhythmias, Cardiac; Chlorpromazine; Digitalis Glycosides; Humans; Pharmacology; Potassium; Procain | 1963 |
[EFFECT OF AMINAZIN ON EXPERIMENTAL ARRHYTHMIA OF CENTRAL ORIGIN].
Topics: Arrhythmias, Cardiac; Brain; Cats; Cerebral Ventricles; Chlorpromazine; Electric Stimulation; Electr | 1964 |
ELECTROCARDIOGRAPHIC FINDINGS IN CONNECTION WITH A CLINICAL TRIAL OF CHLORPROMAZINE. WITH PARTICULAR REFERENCE TO T WAVE CHANGES AND THE DURATION OF VENTRICULAR ACTIVITY.
Topics: Arrhythmias, Cardiac; Biomedical Research; Chlorpromazine; Electrocardiography; Heart Conduction Sys | 1964 |
DIFFERENTIAL EFFECTS OF SOME PHENOTHIAZINE DERIVATIVES AGAINST CALCIUM-INDUCED VENTRICULAR ARRHYTHMIAS IN THE ISOLATED RABBIT HEART.
Topics: Antipsychotic Agents; Arrhythmias, Cardiac; Brugada Syndrome; Calcium; Calcium Chloride; Cardiac Con | 1964 |
Mechanism of chlorpromazine-induced arrhythmia -- arrhythmia and mitochondrial dysfunction.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cardiac Complexes, Premature; Chlorpromazine; Coenzym | 1981 |
Untoward effects following combined neuroleptic-lithium therapy. Cardiac arrhythmias and seizure.
Topics: Adult; Arrhythmias, Cardiac; Bipolar Disorder; Chlorpromazine; Drug Therapy, Combination; Epilepsy, | 1980 |
Electrocardiographic changes and cardiac arrhythmias in patients receiving psychotropic drugs.
Topics: Adrenergic Agonists; Adult; Aged; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Cardiovasc | 1976 |
Protection of chlorpromazine-induced arrhythmia by flavin-adenine-dinucleotide in canine heart.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Chlorpromazine; Dogs; Flavin-Adenine Dinucleotide; Mi | 1979 |
Phenothiazine cardiomyopathy: electrolyte alterations in serum and cardiac tissue of rabbits with acute thorazine intoxication.
Topics: Animals; Arrhythmias, Cardiac; Chlorpromazine; Electrolytes; Female; Heart Diseases; Male; Myocardiu | 1977 |
The prolongation of QRS-duration resulting from delayed recovery of ventricular excitability. A new mechanism for intraventricular conduction disturbance. A preliminary note.
Topics: Animals; Arrhythmias, Cardiac; Chlorpromazine; Disease Models, Animal; Dogs; Electrocardiography; He | 1976 |
Automaticity and time-dependent conduction disturbance produced in canine ventricular myocardium. New aspects for initiation of ventricular arrhythmias.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Chlorpromazine; Depression, Chemical; Dogs; Heart | 1976 |
Arrhythmias and inhibition of noradrenaline uptake caused by tricyclic antidepressants and chlorpromazine on the isolated perfused rabbit heart.
Topics: Animals; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Chlorpromazine; Cocaine; Coronary C | 1975 |
Does chlorpromazine produce cardiac arrhythmia via the central nervous system?
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Central Nervous System; Chlorpromazine; Decereb | 1988 |
[Long-term ECG control in gastroscopies using Obsidan and Elroquil premedication].
Topics: Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Chlorpromazine; Electrocardiography; Female; G | 1987 |
Chlorpromazine: cardiac arrhythmogenicity in the cat.
Topics: Adrenal Glands; Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Chlorpromazine; Dose-Response R | 1986 |
Adverse effects of meperidine, promethazine, and chlorpromazine for sedation in pediatric patients.
Topics: Adolescent; Arrhythmias, Cardiac; Biopsy; Blood Pressure; Cardiac Catheterization; Child, Preschool; | 1985 |
Treatment of sympathetic overactivity in tetanus.
Topics: Adult; Aged; Anesthesia, General; Arrhythmias, Cardiac; Blood Pressure; Cardiovascular Diseases; Chi | 1969 |
Concerning the influence of non-specific brain-stem structures on the vegetative functions of the brain in cerebral pathology.
Topics: Animals; Arrhythmias, Cardiac; Body Temperature; Cats; Chlorpromazine; Electroencephalography; Hemat | 1969 |
Electrocardiogram of the month.
Topics: Arrhythmias, Cardiac; Chlorpromazine; Electrocardiography; Female; Heart Rate; Humans; Middle Aged; | 1972 |
Electrocardiographic changes induced by some phenothiazine derivatives.
Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Atropine; Chlorpromazine; Dogs; Electrocardiography; Pota | 1973 |
Successful prolonged resuscitation after open heart surgery.
Topics: Adult; Arrhythmias, Cardiac; Atrial Fibrillation; Blood Gas Analysis; Blood Pressure; Bradycardia; B | 1971 |
Correlation of chemical structure of phenothiazines with their coronary dilator and antiarrhythmic activities.
Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chlorpromazine; Coronary Vessels; | 1971 |
Management of anaesthesia for phaeochromocytoma.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Anesthesia, General; Arrhythmias, Cardiac; Blood Pressur | 1972 |
Electrocardiographic and ultrastructural cardiac effects of phenothiazine in rabbits: a preliminary report.
Topics: Animals; Arrhythmias, Cardiac; Aspartate Aminotransferases; Chlorpromazine; Creatine Kinase; Electro | 1972 |
The current usage of hypothermia in British neurosurgery.
Topics: Anesthesia, General; Arrhythmias, Cardiac; Blood Pressure; Body Temperature; Central Venous Pressure | 1971 |
The influence of neurotropic drugs on experimental arrhythmia evoked by local stimulation of the bulbar reticular formation.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Brain Stem; Cats; Chlorpromazine; Electric Stimulatio | 1967 |
[Mescaline induced bradycardia and its antagonistic modification by chlorpromazine, pentobarbital and scopolamine after injection into lateral cerebral ventricle of mouse].
Topics: Animals; Arrhythmias, Cardiac; Bradycardia; Cerebral Ventricles; Chlorpromazine; Depression, Chemica | 1970 |
Operative correction and postoperative management of transposition of the great vessels in nine children.
Topics: Arrhythmias, Cardiac; Blood Pressure; Blood Volume; Child; Child, Preschool; Chlorpromazine; Humans; | 1969 |