chlorpromazine has been researched along with Amenorrhea in 30 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Amenorrhea: Absence of menstruation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two euprolactinemic women with hypothalamic amenorrhea, previously unsuccessfully submitted to clomiphene citrate therapy, were treated with bromocriptine." | 7.66 | Bromocriptine induced pregnancy in two cases of euprolactinemic hypothalamic amenorrhea. ( Dorato, F; Miragoli, A; Nencioni, T; Polvani, F, 1978) |
| "TRH, metoclopramide (MCP), chlorpromazine (CPZ), and insulin (ITT) stimulation tests of PRL secretion were carried out in age-matched controls and before and after successful removal of pituitary prolactinomas in women with the galactorrhea-amenorrhea syndrome." | 3.66 | Persistent defect in regulation of prolactin secretion after successful pituitary tumor removal in women with the galactorrhea-amenorrhea syndrome. ( Blackard, WG; Gardner, DF; Lankford, HV; Tucker, HS, 1980) |
| "Two euprolactinemic women with hypothalamic amenorrhea, previously unsuccessfully submitted to clomiphene citrate therapy, were treated with bromocriptine." | 3.66 | Bromocriptine induced pregnancy in two cases of euprolactinemic hypothalamic amenorrhea. ( Dorato, F; Miragoli, A; Nencioni, T; Polvani, F, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| WINNIK, HZ | 1 |
| TENNENBAUM, L | 1 |
| GAULHOFER, WK | 1 |
| SCHAANK, JR | 1 |
| VALI, A | 1 |
| COLMEIRO-LAFORET, K | 1 |
| HAUSER, GA | 1 |
| KRESSIG, R | 1 |
| KELLER, M | 1 |
| WENNER, R | 2 |
| BATTEGAY, R | 1 |
| BERGER, J | 1 |
| TACHEZY, R | 2 |
| VINAROVA, M | 1 |
| COLE, PV | 1 |
| KLEIN, JJ | 1 |
| SEGAL, RL | 1 |
| WARNER, RR | 1 |
| MORETTI, O | 1 |
| Corenblum, B | 1 |
| Taylor, PJ | 1 |
| Tucker, HS | 2 |
| Lankford, HV | 2 |
| Gardner, DF | 1 |
| Blackard, WG | 2 |
| Grubb, SR | 1 |
| Wigand, JP | 1 |
| Taylon, A | 1 |
| Becker, DP | 1 |
| Kidd, GS | 1 |
| Dimond, R | 1 |
| Kark, JA | 1 |
| Whorton, N | 1 |
| Vigersky, RA | 1 |
| Hagen, TC | 1 |
| Sill, AJ | 1 |
| Garthwaite, TL | 1 |
| Halverson, G | 1 |
| Borkowf, HI | 1 |
| Nencioni, T | 1 |
| Miragoli, A | 1 |
| Dorato, F | 1 |
| Polvani, F | 1 |
| Boyd, AE | 1 |
| Reichlin, S | 1 |
| Turksoy, RN | 2 |
| Rjosk, HK | 1 |
| Goebel, R | 1 |
| Schaison, G | 1 |
| Nathan, C | 1 |
| L'Hermite, M | 1 |
| Kato, Y | 1 |
| Schermann, J | 1 |
| Archer, DF | 1 |
| Josimovich, JB | 1 |
| Maroon, JC | 1 |
| Malarkey, WB | 1 |
| Del Pozo, E | 1 |
| Varga, L | 1 |
| Wyss, H | 1 |
| Tolis, G | 1 |
| Friesen, H | 1 |
| Vetter, L | 1 |
| Uettwiler, A | 1 |
| Zárate, A | 1 |
| Jacobs, LS | 1 |
| Canales, ES | 1 |
| Schally, AV | 1 |
| De la Cruz, A | 1 |
| Soria, J | 1 |
| Daughaday, WH | 1 |
| Santen, RJ | 1 |
| Bardin, CW | 1 |
| Turkington, RW | 1 |
| Dally, P | 1 |
| Lehto, S | 1 |
| Lydecken, K | 1 |
| Kurachi, K | 1 |
| Ozaki, M | 1 |
| Tani, T | 1 |
| Mitsui, I | 1 |
| Miyazaki, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Reproductive Hormonal Alterations in Obesity, AIMS #1 & #2[NCT01457703] | 62 participants (Actual) | Interventional | 2010-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Follicle-stimulating hormone was measured hourly during the 12 hour study visit, and was compared between the obese and normal weight groups. (NCT01457703)
Timeframe: Measured hourly and averaged over the 12 hour study visit
| Intervention | IU/L (Mean) |
|---|---|
| BMI ≥30 kg/m2 | 3.8 |
| BMI 18-25 kg/m2 | 3.3 |
Follicle-stimulating hormone was measured hourly during the 12 hour study visit, and was compared between the obese and normal weight groups. (NCT01457703)
Timeframe: Measured hourly and averaged over the 12 hour study visit
| Intervention | IU/L (Mean) |
|---|---|
| BMI ≥30 kg/m2 | 5.31 |
| BMI 18-25 kg/m2 | 6.18 |
Luteinizing Hormone (LH) Pulse Amplitude was measured hourly during the 12 hour study visit, and was compared between the obese and normal weight groups. (NCT01457703)
Timeframe: Measured hourly and averaged over the 12 hour study visit
| Intervention | IU/L (Mean) |
|---|---|
| BMI ≥30 kg/m2 | 4.1 |
| BMI 18-25 kg/m2 | 3.6 |
Luteinizing Hormone (LH) Pulse Amplitude was measured hourly during the 12 hour study visit, and was compared between the obese and normal weight groups. (NCT01457703)
Timeframe: Measured hourly and averaged over the 12 hour study visit
| Intervention | IU/L (Mean) |
|---|---|
| BMI ≥30 kg/m2 | 2.21 |
| BMI 18-25 kg/m2 | 4.44 |
Pregnanediol glucuronide (PdG) was collected daily over the course of one menstrual cycle and averaged. (NCT01457703)
Timeframe: Averaged over the length of menstrual cycle
| Intervention | ug/cycle (Mean) |
|---|---|
| BMI ≥30 kg/m2 | 54.1 |
| BMI 18-25 kg/m2 | 88.7 |
1 review available for chlorpromazine and Amenorrhea
| Article | Year |
|---|---|
[Determination of serum prolactin].
Topics: 5-Hydroxytryptophan; Amenorrhea; Brain Diseases; Chlorpromazine; Female; Galactorrhea; Humans; Hypot | 1976 |
29 other studies available for chlorpromazine and Amenorrhea
| Article | Year |
|---|---|
[Appearance of galactorrhea during largactil therapy].
Topics: Amenorrhea; Chlorpromazine; Female; Galactorrhea; Humans; Lactation Disorders; Pregnancy | 1955 |
[Galactorrhea due to chlorpromazine].
Topics: Amenorrhea; Chlorpromazine; Female; Galactorrhea; Humans; Lactation Disorders; Pregnancy | 1957 |
[Galactorrhea in chlorpromazine therapy].
Topics: Amenorrhea; Breast Diseases; Chlorpromazine; Female; Galactorrhea; Humans; Lactation Disorders; Preg | 1957 |
[Amenorrhea caused by largactil (megaphen)].
Topics: Amenorrhea; Chlorpromazine; Female; Humans | 1958 |
[Galactorrhea in psychiatric therapy].
Topics: Amenorrhea; Chlorpromazine; Female; Galactorrhea; Humans; Lactation Disorders; Pregnancy | 1962 |
[Galactorrhea in a male induced by ovarian hormone and chlorpromazine].
Topics: Amenorrhea; Chlorpromazine; Female; Galactorrhea; Humans; Lactation Disorders; Male; Medical Records | 1962 |
A NEW CHLORPROMAZINE SIDE-EFFECT?
Topics: Amenorrhea; Chlorpromazine; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Toxicol | 1964 |
GALACTORRHEA DUE TO IMIPRAMINE. REPORT OF A CASE.
Topics: Amenorrhea; Chlorpromazine; Depression; Depressive Disorder; Female; Galactorrhea; Humans; Hypothyro | 1964 |
[Chlorpromazine and appearance of galactorrhea].
Topics: Amenorrhea; Chlorpromazine; Female; Galactorrhea; Humans; Lactation Disorders; Pregnancy | 1960 |
A rationale for the use of bromocriptine in patients with amenorrhea and normoprolactinemia.
Topics: Adult; Amenorrhea; Bromocriptine; Chlorpromazine; Female; Humans; Menstruation; Prolactin; Thyrotrop | 1980 |
Persistent defect in regulation of prolactin secretion after successful pituitary tumor removal in women with the galactorrhea-amenorrhea syndrome.
Topics: Amenorrhea; Chlorpromazine; Female; Galactorrhea; Humans; Insulin; Lactation Disorders; Metocloprami | 1980 |
Galactorrhea-amenorrhea syndrome: follow-up of forty-five patients after pituitary tumor removal.
Topics: Adenoma; Adult; Amenorrhea; Chlorpromazine; Female; Follow-Up Studies; Galactorrhea; Humans; Lactati | 1981 |
The effects of pyridoxine on pituitary hormone secretion in amenorrhea-galactorrhea syndromes.
Topics: Adult; Amenorrhea; Chlorpromazine; Female; Galactorrhea; Humans; Lactation Disorders; Levodopa; Pitu | 1982 |
Prolactin and growth hormone responses in the amenorrhea-galactorrhea syndrome.
Topics: Amenorrhea; Chlorpromazine; Female; Galactorrhea; Growth Hormone; Humans; Lactation Disorders; Levod | 1980 |
Bromocriptine induced pregnancy in two cases of euprolactinemic hypothalamic amenorrhea.
Topics: Adult; Amenorrhea; Bromocriptine; Chlorpromazine; Estradiol; Female; Follicle Stimulating Hormone; H | 1978 |
Galactorrhea-amenorrhea syndrome: diagnosis and therapy.
Topics: Adenoma; Adult; Amenorrhea; Chlorpromazine; Contraceptives, Oral, Synthetic; Estradiol; Female; Foll | 1977 |
[The olfactor-genital syndrome (author's transl)].
Topics: Adult; Amenorrhea; Chlorpromazine; Chorionic Gonadotropin; Female; Follicle Stimulating Hormone; Hum | 1978 |
Response of amenorrheic patients with normal serum prolactin to chlorpromazine during administration of human menopausal gonadotropin.
Topics: Amenorrhea; Chlorpromazine; Estradiol; Estrogens; Female; Menotropins; Menstruation; Prolactin | 1978 |
[ Study of prolactin and blood gonadotropins in amenorrheas-galactorrhea. Dynamic exploation in 13 cases].
Topics: Adenoma; Adult; Amenorrhea; Chlorpromazine; Dihydroxyphenylalanine; Female; Follicle Stimulating Hor | 1975 |
[Abnormal galactorrhea and the amenorrhea-galactorrhea syndrome].
Topics: Amenorrhea; Chiari-Frommel Syndrome; Chlorpromazine; Female; Galactorrhea; Humans; Hypothyroidism; I | 1976 |
Chlorpromazine-induced changes in serum prolactin in women with oligomenorrhea, amenorrhea, and pituitary adenoma.
Topics: Adenoma; Amenorrhea; Chlorpromazine; Female; Humans; Hypothalamus; Menstruation Disturbances; Oligom | 1977 |
Nonpuerperal lactation and normal prolactin regulation.
Topics: Adult; Amenorrhea; Chlorpromazine; Circadian Rhythm; Estrogens; Female; Follicle Stimulating Hormone | 1975 |
Clinical and hormonal response to bromocriptin (CB-154) in the galactorrhea syndromes.
Topics: Adult; Amenorrhea; Bromine; Chlorpromazine; Contraceptives, Oral; Ergot Alkaloids; Female; Follicle | 1974 |
Functional evaluation of pituitary reserve in patients with the amenorrhea-galactorrhea syndrome utilizing luteinizing hormone-releasing hormone (LH-RH), L-dopa and chlorpromazine.
Topics: Adult; Amenorrhea; Chlorpromazine; Dihydroxyphenylalanine; Female; Follicle Stimulating Hormone; Gon | 1973 |
Episodic luteinizing hormone secretion in man. Pulse analysis, clinical interpretation, physiologic mechanisms.
Topics: Adult; Amenorrhea; Anorexia Nervosa; Chlorpromazine; Female; Follicle Stimulating Hormone; Half-Life | 1973 |
Serum prolactin levels in patients with gynecomastia.
Topics: Adolescent; Adult; Amenorrhea; Animals; Caseins; Cell Line; Chlorpromazine; Choriocarcinoma; Gynecom | 1972 |
Anorexia nervosa.
Topics: Adolescent; Amenorrhea; Anorexia Nervosa; Body Weight; Chlorpromazine; Female; Humans; Male; Prognos | 1972 |
[Therapeutic amenorrhea].
Topics: Adolescent; Adult; Aggression; Alanine Transaminase; Amenorrhea; Aspartate Aminotransferases; Chlorp | 1971 |
[Clinical picture of gonadotropin secretion anomalies].
Topics: Adult; Amenorrhea; Chiari-Frommel Syndrome; Chlorpromazine; Female; Gonadotropins; Humans; Hypopitui | 1968 |