chlorpromazine has been researched along with Alloxan Diabetes in 14 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Both groups were subdivided into the three groups and administered with 0, 5 or 50 mg CPZ per kg body weight (control, low dosage of chlorpromazine (LCPZ), high dosage chlorpromazine (HCPZ)) for 8 weeks." | 1.35 | Chlorpromazine attenuates pancreatic beta-cell function and mass through IRS2 degradation, while exercise partially reverses the attenuation. ( Hong, SM; Kim, SH; Lee, JE; Park, S; Sung, SR, 2008) |
| " Vasoconstriction was induced by epinephrine in all groups in a dose-response fashion." | 1.30 | Vascular effects of epinephrine, lisinopril, and chlorpromazine in diabetic and non-diabetic rats. ( Aygit, AC; Ayhan, MS; Demiralay, A; Yildirim, I, 1999) |
| "When chlorpromazine was administered to the rats treated with bromocriptine, an inhibitor of pituitary prolactin secretion, aldose reductase activity in the ovary was significantly elevated compared with that in the rats treated with chlorpromazine alone." | 1.29 | Hormonal regulation of aldose reductase in rat ovary during the estrous cycle. ( Endo, T; Hara, S; Iwata, N; Mukai, T; Nishimura, C; Takahashi, M; Takayama, M, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (71.43) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Miao, GX | 1 |
| Wang, YD | 1 |
| Yan, ZW | 1 |
| Zhang, LY | 1 |
| TURUNEN, M | 1 |
| PASILA, M | 1 |
| FISTER, V | 1 |
| RABADJIJA, L | 1 |
| BAIC, D | 1 |
| SIMOES, MS | 1 |
| OSSWALD, W | 1 |
| Quevauviller, A | 1 |
| Boizard, F | 1 |
| Park, S | 1 |
| Hong, SM | 1 |
| Lee, JE | 1 |
| Sung, SR | 1 |
| Kim, SH | 1 |
| Jori, A | 1 |
| Bianchetti, A | 1 |
| Wizniewski, K | 1 |
| Buczko, W | 2 |
| Iwata, N | 1 |
| Hara, S | 1 |
| Nishimura, C | 1 |
| Takahashi, M | 1 |
| Mukai, T | 1 |
| Takayama, M | 1 |
| Endo, T | 1 |
| Aygit, AC | 1 |
| Ayhan, MS | 1 |
| Demiralay, A | 1 |
| Yildirim, I | 1 |
| Wiśniewski, K | 2 |
| Kocialski, AB | 1 |
| Marozzi, FJ | 1 |
| Malone, MH | 1 |
| Mennear, JH | 1 |
| Miya, TS | 1 |
| Danysz, A | 1 |
| Moniuszko, J | 1 |
| Zarebski, M | 1 |
14 other studies available for chlorpromazine and Alloxan Diabetes
| Article | Year |
|---|---|
Synthesis, in vitro ADME profiling and in vivo pharmacological evaluation of novel glycogen phosphorylase inhibitors.
Topics: Animals; Blood Glucose; Cell Proliferation; Diabetes Mellitus, Experimental; Dose-Response Relations | 2020 |
Effects of anesthesia and operation on blood sugar; an experimental study on normal and alloxandiabetic rabbits.
Topics: Anesthesia; Anesthesiology; Animals; Blood Glucose; Chlorpromazine; Diabetes Mellitus, Experimental; | 1957 |
[The significance of largactil in the development of alloxan diabetes in rats].
Topics: Animals; Chlorpromazine; Diabetes Mellitus, Experimental; Rats | 1959 |
Chlorpromazine protection against alloxan diabetes.
Topics: Animals; Chlorpromazine; Diabetes Mellitus, Experimental | 1955 |
[A comparative study of the activity of chlorpromazine and meprobamate in healthy mice and those made diabetic with alloxan].
Topics: Alloxan; Animals; Anti-Anxiety Agents; Chlorpromazine; Diabetes Mellitus, Experimental; Dopamine Ant | 1979 |
Chlorpromazine attenuates pancreatic beta-cell function and mass through IRS2 degradation, while exercise partially reverses the attenuation.
Topics: Acetophenones; Animals; Antipsychotic Agents; Benzopyrans; Chlorpromazine; Diabetes Mellitus, Experi | 2008 |
Effect of benzyloxyguanidine (13958 RP) on the increase of blood glucose and plasma free fatty acids induced by various drugs in rats.
Topics: Animals; Blood Glucose; Body Temperature; Chlorpromazine; Diabetes Mellitus, Experimental; Diazoxide | 1967 |
The central pharmacological effect of chlorpromazine in rats with alloxan-diabetes.
Topics: Animals; Avoidance Learning; Biological Transport; Brain; Chlorpromazine; Diabetes Mellitus, Experim | 1967 |
Hormonal regulation of aldose reductase in rat ovary during the estrous cycle.
Topics: Aldehyde Reductase; Animals; Bromocriptine; Chlorpromazine; Chorionic Gonadotropin; Diabetes Mellitu | 1996 |
Vascular effects of epinephrine, lisinopril, and chlorpromazine in diabetic and non-diabetic rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Chlorpromazine; Diabetes Mellitus, Experimental; | 1999 |
[The studies on "nonspecific transport effect" of insulin].
Topics: Adenosine Triphosphatases; Animals; Biological Transport; Brain Chemistry; Cell Membrane Permeabilit | 1968 |
Effects of certain nonsteroid anti-inflammatory drugs, tolbutamide, and tetrahydroalstonine on blood glucose and carrageen in-induced pedal edema in rats.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Blood Glucose; Carrageenan; Chlorpromazine; Diabetes M | 1972 |
Chlorpromazine-induced glucose intolerance in the mouse.
Topics: Animals; Chlorpromazine; Diabetes Mellitus, Experimental; Epinephrine; Fasting; Hyperglycemia; Liver | 1970 |
[Effect of certain drugs in alloxan diabetes].
Topics: Animals; Chlorpromazine; Diabetes Mellitus, Experimental; Epinephrine; Mice; Neostigmine; Sodium Sal | 1968 |