chlorpromazine has been researched along with Akinetic-Rigid Variant of Huntington Disease in 25 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, the performances of Huntington's disease subjects appeared to be different when compared to the other two groups." | 2.69 | Kinematic analysis of the reach to grasp movement in Parkinson's and Huntington's disease subjects. ( Bonfiglioli, C; Castiello, U; De Berti, G; Nichelli, P; Nicoletti, R, 1998) |
| "Tetrabenazine alone, was restarted after 48 hours to control her Huntington's Chorea and there was no recurrence of parkinsonism." | 1.27 | Iatrogenic parkinsonism in Huntington's chorea. ( Moss, JH; Stewart, DE, 1986) |
| "Eight individuals with Huntington's chorea had low basal and impaired human prolactin responses to both chlorpromazine and thyrotrophin-releasing hormone." | 1.26 | Impaired prolactin release in Huntington's chorea. Evidence for dopaminergic excess. ( Beighton, P; Hayden, MR; Paul, M; Vinik, AI, 1977) |
| "Huntington's disease (Huntington's chorea), a degenerative disorder of the central nervous system, is inherited in an autosomal dominant pattern." | 1.26 | Huntington's disease: current concepts of therapy. ( Goetz, CG; Weiner, WJ, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (80.00) | 18.7374 |
| 1990's | 4 (16.00) | 18.2507 |
| 2000's | 1 (4.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| WALTHER-BUEL, H | 2 |
| PAOLOZZI, C | 1 |
| NAYRAC, P | 1 |
| ARNOTT, G | 1 |
| MILBLED, G | 1 |
| LASCELLES, CF | 1 |
| RISER, M | 1 |
| GAYRAL, L | 1 |
| STERN, H | 1 |
| TURNIN, J | 1 |
| MILLET, L | 1 |
| Schilling, G | 1 |
| Savonenko, AV | 1 |
| Coonfield, ML | 1 |
| Morton, JL | 1 |
| Vorovich, E | 1 |
| Gale, A | 1 |
| Neslon, C | 1 |
| Chan, N | 1 |
| Eaton, M | 1 |
| Fromholt, D | 1 |
| Ross, CA | 1 |
| Borchelt, DR | 1 |
| Gale, K | 1 |
| Casu, M | 1 |
| Barbosa, ER | 1 |
| Marchiori, PE | 1 |
| Scaff, M | 1 |
| de Assis, JL | 1 |
| Folstein, S | 1 |
| Folstein, M | 1 |
| Bonfiglioli, C | 1 |
| De Berti, G | 1 |
| Nichelli, P | 1 |
| Nicoletti, R | 1 |
| Castiello, U | 1 |
| Hayden, MR | 1 |
| Vinik, AI | 1 |
| Paul, M | 1 |
| Beighton, P | 1 |
| Müller, EE | 1 |
| Cocchi, D | 1 |
| Mantegazza, P | 1 |
| Parati, EA | 1 |
| Caraceni, T | 1 |
| Bailey, E | 1 |
| Bond, PA | 1 |
| Brooks, BA | 1 |
| Dimitrakoudi, M | 1 |
| Jenner, FA | 1 |
| Judd, A | 1 |
| Lee, CR | 1 |
| Lenton, EA | 1 |
| McNeil, S | 1 |
| Pollitt, RJ | 1 |
| Sampson, GA | 1 |
| Thompson, EA | 1 |
| Glaeser, BS | 1 |
| Vogel, WH | 1 |
| Oleweiler, DB | 1 |
| Hare, TA | 1 |
| Caine, E | 1 |
| Kartzinel, R | 1 |
| Ebert, M | 1 |
| Carter, AC | 1 |
| Goetz, CG | 1 |
| Weiner, WJ | 2 |
| Levy, CL | 1 |
| Carlson, HE | 1 |
| Sowers, JR | 1 |
| Goodlett, RE | 1 |
| Tourtellotte, WW | 1 |
| Hershman, JM | 1 |
| Oke, AF | 1 |
| Putz, C | 1 |
| Adams, RN | 1 |
| Bird, ED | 1 |
| Waldman, AJ | 1 |
| Stewart, JT | 1 |
| Feinberg, TE | 1 |
| Cianci, CD | 1 |
| Morrow, JS | 1 |
| Pehta, JC | 1 |
| Redman, CM | 1 |
| Huima, T | 1 |
| Koroshetz, WJ | 1 |
| Moss, JH | 1 |
| Stewart, DE | 1 |
| Tan, BK | 1 |
| Leijnse-Ybema, HJ | 1 |
| v d Brand, HJ | 1 |
| Klawans, HL | 1 |
| Mattsson, B | 1 |
| Persson, SA | 1 |
| Schergna, E | 1 |
1 review available for chlorpromazine and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
Dynamic utilization of GABA in substantia nigra: regulation by dopamine and GABA in the striatum, and its clinical and behavioral implications.
Topics: 4-Aminobutyrate Transaminase; Afferent Pathways; Aminocaproates; Animals; Basal Ganglia; Behavior, A | 1981 |
2 trials available for chlorpromazine and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
Kinematic analysis of the reach to grasp movement in Parkinson's and Huntington's disease subjects.
Topics: Adult; Age of Onset; Aged; Analysis of Variance; Antiparkinson Agents; Basal Ganglia; Chlorpromazine | 1998 |
Neuroendocrine function in Huntington's disease: dopaminergic regulation of prolactin release.
Topics: Adult; Bromocriptine; Carbidopa; Chlorpromazine; Dopamine; Female; Humans; Huntington Disease; Levod | 1978 |
22 other studies available for chlorpromazine and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
The action of neuroleptic drugs in Huntington's disease.
Topics: Chlorpromazine; Humans; Huntington Disease; Reserpine | 1956 |
The action of neuroleptic drugs in Huntington's disease.
Topics: Chlorpromazine; Humans; Huntington Disease; Reserpine | 1956 |
The action of neuroleptic drugs in Huntington's disease.
Topics: Chlorpromazine; Humans; Huntington Disease; Reserpine | 1956 |
The action of neuroleptic drugs in Huntington's disease.
Topics: Chlorpromazine; Humans; Huntington Disease; Reserpine | 1956 |
[A case of death caused by acute gastric atonia during phenothiazine therapy].
Topics: Chlorpromazine; Gastrointestinal Tract; Gastroparesis; Humans; Huntington Disease; Paralysis; Phenot | 1957 |
[HUNTINGTON'S CHOREA, HUMOR DISORDERS WITH MANIC MANIFESTATIONS, BENEFICIAL EFFECTS OF HALOPERIDOL (FLUOROPHENYLPIPERIDINOBUTYROPHENONE). ABSENCE OF THE THERAPEUTIC AKINETO-HYPERTONIC SYNDROME].
Topics: Bipolar Disorder; Chlorpromazine; Chorea; Electroencephalography; Electromyography; Haloperidol; Hum | 1964 |
HUNTINGTON'S CHOREA.
Topics: Barbiturates; Cerebral Cortex; Chlorpromazine; Chorea; Drug Therapy; Huntington Disease; Pathology; | 1964 |
[Treatment of Huntington's chorea with chlorpromazine (largactil) and thioridazine (melleril)].
Topics: Chlorpromazine; Chorea; Huntington Disease; Thioridazine; Tranquilizing Agents | 1959 |
Environmental, pharmacological, and genetic modulation of the HD phenotype in transgenic mice.
Topics: Acetamides; Animals; Celecoxib; Chlorpromazine; Coenzymes; Cyclooxygenase Inhibitors; Disease Models | 2004 |
[Huntington chorea: report of 16 cases].
Topics: Adult; Aged; Brain Diseases; Chlorpromazine; Dementia; Diagnosis, Differential; Female; gamma-Aminob | 1983 |
Diagnosis and treatment of Huntington's disease.
Topics: Affective Symptoms; Amitriptyline; Chlorpromazine; Cognition Disorders; Counseling; Deglutition Diso | 1981 |
Impaired prolactin release in Huntington's chorea. Evidence for dopaminergic excess.
Topics: Adolescent; Adult; Aged; Chlorpromazine; Dopamine; Female; Humans; Huntington Disease; Hypothalamus; | 1977 |
Prolactin control in Huntington's chorea.
Topics: Adult; Chlorpromazine; Humans; Huntington Disease; Hypothalamus; Middle Aged; Pituitary Gland, Anter | 1977 |
The medicinal chemistry of lithium.
Topics: Adenylyl Cyclases; Adrenal Cortex; Affective Symptoms; Animals; Antidepressive Agents; Bipolar Disor | 1975 |
GABA levels in cerebrospinal fluid of patients with Huntington's chorea: a preliminary report.
Topics: Adult; Aged; Aminobutyrates; Amitriptyline; Chlorpromazine; Diazepam; Female; gamma-Aminobutyric Aci | 1975 |
Huntington's disease: current concepts of therapy.
Topics: Acetylcholine; Adolescent; Adult; Butyrophenones; Child; Chlorpromazine; Dopamine Antagonists; gamma | 1979 |
Growth hormone and prolactin secretion in Huntington's disease.
Topics: Adult; Aged; Apomorphine; Chlorpromazine; Female; Growth Hormone; Humans; Huntington Disease; Levodo | 1979 |
Neuroleptic treatment is an unlikely cause of elevated dopamine in thalamus of schizophrenic subjects.
Topics: Adult; Aged; Antipsychotic Agents; Chlorpromazine; Dopamine; Haloperidol; Humans; Huntington Disease | 1992 |
Chlorpromazine & appetite.
Topics: Anorexia; Chlorpromazine; Humans; Huntington Disease; Male; Middle Aged | 1991 |
Diagnostic tests for choreoacanthocytosis.
Topics: Acanthocytes; Atrophy; Blood Cells; Brain; Chlorpromazine; Chorea; Corpus Striatum; Edetic Acid; Fem | 1991 |
Iatrogenic parkinsonism in Huntington's chorea.
Topics: Chlorpromazine; Drug Interactions; Female; Humans; Huntington Disease; Middle Aged; Parkinson Diseas | 1986 |
Levodopa in Huntington's chorea.
Topics: Chlorpromazine; Dihydroxyphenylalanine; Female; Humans; Huntington Disease; Mental Disorders; Middle | 1972 |
Lingual-facial-buccal movements in the elderly. I. Pathophysiology and treatment.
Topics: Aged; Amphetamine; Chemoreceptor Cells; Chlorpromazine; Corpus Striatum; Dopamine Antagonists; Facia | 1973 |
Cerebrospinal homovanillic acid and 5-hydroxyindoleacetic acid in huntington's chorea.
Topics: Adult; Chlormethiazole; Chlorpromazine; Female; Fluphenazine; Haloperidol; Homovanillic Acid; Humans | 1974 |
[Recent therapeutic conquests in extrapyramidal syndromes].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Amantadine; Athetosis; Brain Diseases; Central | 1970 |