chlorpromazine has been researched along with Age-Related Memory Disorders in 12 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We measured BOLD-response during a WM task in a longitudinal fMRI-study in eleven schizophrenia patients first when they received conventional antipsychotics (T1) and a second time after they had been switched to aripiprazole (T2)." | 7.76 | Switching schizophrenia patients from typical neuroleptics to aripiprazole: effects on working memory dependent functional activation. ( Beck, A; Dembler, T; Dinges, M; Friedel, E; Gallinat, J; Heinz, A; Juckel, G; Sarkar, R; Schlagenhauf, F; Wrase, J; Wüstenberg, T, 2010) |
| "We measured BOLD-response during a WM task in a longitudinal fMRI-study in eleven schizophrenia patients first when they received conventional antipsychotics (T1) and a second time after they had been switched to aripiprazole (T2)." | 3.76 | Switching schizophrenia patients from typical neuroleptics to aripiprazole: effects on working memory dependent functional activation. ( Beck, A; Dembler, T; Dinges, M; Friedel, E; Gallinat, J; Heinz, A; Juckel, G; Sarkar, R; Schlagenhauf, F; Wrase, J; Wüstenberg, T, 2010) |
| " Further drug-like property analysis demonstrated that the optimized compound, 8d (WI-1758), had liver microsomal metabolic stability, was well tolerated (>2000 mg/kg), and had a rational pharmacokinetic profile, as well as an oral bioavailability of 14." | 1.48 | Design, Synthesis, and Evaluation of Orally Bioavailable Quinoline-Indole Derivatives as Innovative Multitarget-Directed Ligands: Promotion of Cell Proliferation in the Adult Murine Hippocampus for the Treatment of Alzheimer's Disease. ( Chan, ASC; Feng, X; Hu, J; Huang, L; Li, X; Wang, Z; Yang, X, 2018) |
| "Patients with schizophrenia have widespread cognitive impairments, with selective deficits in relational memory." | 1.38 | Revised associative inference paradigm confirms relational memory impairment in schizophrenia. ( Armstrong, K; Heckers, S; Williams, LE, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 7 (58.33) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Z | 1 |
| Hu, J | 1 |
| Yang, X | 1 |
| Feng, X | 1 |
| Li, X | 1 |
| Huang, L | 1 |
| Chan, ASC | 1 |
| Forbes, NF | 1 |
| Carrick, LA | 1 |
| McIntosh, AM | 1 |
| Lawrie, SM | 1 |
| Schlagenhauf, F | 1 |
| Dinges, M | 1 |
| Beck, A | 1 |
| Wüstenberg, T | 1 |
| Friedel, E | 1 |
| Dembler, T | 1 |
| Sarkar, R | 1 |
| Wrase, J | 1 |
| Gallinat, J | 1 |
| Juckel, G | 1 |
| Heinz, A | 1 |
| Armstrong, K | 1 |
| Williams, LE | 1 |
| Heckers, S | 1 |
| Perlstein, WM | 1 |
| Dixit, NK | 1 |
| Carter, CS | 1 |
| Noll, DC | 1 |
| Cohen, JD | 1 |
| Harris, DS | 1 |
| Wolkowitz, OM | 1 |
| Reus, VI | 1 |
| Martínez-Arán, A | 1 |
| Vieta, E | 1 |
| Colom, F | 1 |
| Torrent, C | 1 |
| Sánchez-Moreno, J | 1 |
| Reinares, M | 1 |
| Benabarre, A | 1 |
| Goikolea, JM | 1 |
| Brugué, E | 1 |
| Daban, C | 1 |
| Salamero, M | 1 |
| Schuepbach, D | 1 |
| Hill, SK | 1 |
| Sanders, RD | 1 |
| Hell, D | 1 |
| Keshavan, MS | 1 |
| Sweeney, JA | 1 |
| Nagy, O | 1 |
| Kelemen, O | 1 |
| Erdélyi, R | 1 |
| Pataki, M | 1 |
| Janka, Z | 1 |
| Myers, CE | 1 |
| Gluck, MA | 1 |
| Kéri, S | 1 |
| Calev, A | 1 |
| Venables, PH | 1 |
| Monk, AF | 1 |
| Wright, S | 1 |
| Young, AW | 1 |
| Hellawell, DJ | 1 |
| Huguelet, P | 1 |
| Zanello, A | 1 |
| Nicastro, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Changes in Serum miRNA and BDNF Levels in Bipolar II Depression Treated by Theta-burst Stimulation: A Randomized Sham-controlled Exploratory Study[NCT04998097] | 60 participants (Anticipated) | Interventional | 2022-05-23 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for chlorpromazine and Age-Related Memory Disorders
| Article | Year |
|---|---|
Working memory in schizophrenia: a meta-analysis.
Topics: Antipsychotic Agents; Chlorpromazine; Cognition Disorders; Humans; Memory; Memory Disorders; Psychol | 2009 |
11 other studies available for chlorpromazine and Age-Related Memory Disorders
| Article | Year |
|---|---|
Design, Synthesis, and Evaluation of Orally Bioavailable Quinoline-Indole Derivatives as Innovative Multitarget-Directed Ligands: Promotion of Cell Proliferation in the Adult Murine Hippocampus for the Treatment of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Cell Proliferation; Drug Des | 2018 |
Switching schizophrenia patients from typical neuroleptics to aripiprazole: effects on working memory dependent functional activation.
Topics: Adult; Analysis of Variance; Antipsychotic Agents; Aripiprazole; Brain Mapping; Chlorpromazine; Fema | 2010 |
Revised associative inference paradigm confirms relational memory impairment in schizophrenia.
Topics: Adult; Antipsychotic Agents; Association Learning; Chlorpromazine; Concept Formation; Face; Female; | 2012 |
Prefrontal cortex dysfunction mediates deficits in working memory and prepotent responding in schizophrenia.
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Cognition Disorders; Delayed-Action Preparations; Femal | 2003 |
Movement disorder, memory, psychiatric symptoms and serum DHEA levels in schizophrenic and schizoaffective patients.
Topics: Adult; Aged; Antipsychotic Agents; Chlorpromazine; Dehydroepiandrosterone; Female; Humans; Hydrocort | 2001 |
Cognitive impairment in euthymic bipolar patients: implications for clinical and functional outcome.
Topics: Adult; Anticonvulsants; Antipsychotic Agents; Chlorpromazine; Cognition Disorders; Dysthymic Disorde | 2004 |
Early treatment-induced improvement of negative symptoms predicts cognitive functioning in treatment-naive first episode schizophrenia: a 2-year followup.
Topics: Adolescent; Adult; Antipsychotic Agents; Chlorpromazine; Cognition Disorders; Diagnostic and Statist | 2004 |
[Learned equivalence in schizophrenia: novel method for the measurement of memory functions of the hippocampus and basal ganglia].
Topics: Adult; Antipsychotic Agents; Basal Ganglia; Case-Control Studies; Chlorpromazine; Dopamine Antagonis | 2005 |
Evidence for distinct verbal memory pathologies in severely and mildly disturbed schizophrenics.
Topics: Adult; Age Factors; Chlorpromazine; Chronic Disease; Cues; Humans; Intelligence; Length of Stay; Mal | 1983 |
Sequential Cotard and Capgras delusions.
Topics: Adult; Brain; Capgras Syndrome; Carbamazepine; Chlorpromazine; Delusions; Depressive Disorder; Elect | 1993 |
A study of visual and auditory verbal working memory in schizophrenic patients compared to healthy subjects.
Topics: Adolescent; Adult; Antipsychotic Agents; Auditory Perception; Chlorpromazine; Chronic Disease; Femal | 2000 |