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chlorpromazine and Acute Brain Injuries

chlorpromazine has been researched along with Acute Brain Injuries in 42 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Research Excerpts

ExcerptRelevanceReference
"A patient with neurogenic pulmonary edema was successfully treated with the alpha-blocking agent, chlorpromazine."7.67Chlorpromazine treatment for neurogenic pulmonary edema. ( Howe, JF; Pierce, KR; Tamas, L; Wohns, RN, 1985)
"A patient with neurogenic pulmonary edema was successfully treated with the alpha-blocking agent, chlorpromazine."3.67Chlorpromazine treatment for neurogenic pulmonary edema. ( Howe, JF; Pierce, KR; Tamas, L; Wohns, RN, 1985)
"The effects of aminazin and aspirin on brain injuries in animals with immunological hypersensitivity of the body were studied."3.66[Nerve tissue ultrastructure in experimental brain injuries in animals with increased immunobiologic reactivity following treatment with certain desensitizing drugs]. ( Sukhorukova, LI, 1981)
"Intravenous migraine therapy reduces PTH pain scores for children presenting within 14 days after mTBI."1.42Intravenous migraine therapy in children with posttraumatic headache in the ED. ( Byczkowski, T; Chan, S; Kurowski, B; Timm, N, 2015)
"Fever or pyrexia is a common clinical phenomenon."1.28Fever after traumatic brain injury. ( Segatore, M, 1992)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199037 (88.10)18.7374
1990's2 (4.76)18.2507
2000's2 (4.76)29.6817
2010's1 (2.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chan, S1
Kurowski, B1
Byczkowski, T1
Timm, N1
POCIDALO, JJ1
TARDIEU, C1
DE LANGE, J1
PRIMAC, DW2
MIRSKY, AF2
ROSVOLD, HE2
LECHTENBERG, HW1
UGLOV, FG2
LUCHKO, GD2
OTA, S1
FARETRA, G1
GOZUN, C1
ANSTOCK, F1
MEYER, HH1
HALSWICK, R1
IVANOV, FI1
PAUTLER, EL1
CLARK, G1
Koponen, H1
Larmo, I1
Baguley, IJ1
Cameron, ID1
Green, AM1
Slewa-Younan, S1
Marosszeky, JE1
Gurka, JA1
Rogacheva, SK1
Burakova, NS1
Rosengren, LE2
Persson, LI2
Hoppe, E1
Christensen, L1
Christensen, KN1
Sukhorukova, LI1
Chengappa, KN1
Nimgaonkar, VL1
Bachert, C1
Yang, ZW1
Rabin, BS1
Ganguli, R1
Cold, GE1
Lipper, S1
Tuchman, MM1
Borshchagovskiĭ, ML2
Dubikaitis, IuV2
Segatore, M1
Orlovskaia, DD1
Kleshchinov, VN1
Wohns, RN1
Tamas, L1
Pierce, KR1
Howe, JF1
Buxton Hopkin, DA1
Marsden, CA1
Guldberg, HC1
Petersen, EA1
Haase, J1
Dubinsky, B1
Robichaud, RC1
Goldberg, ME1
Sherman, DM1
Usanov, EI1
Nybäck, H1
Buletsa, BA1
Smirnov, AD1
Lapides, MI1
Mamtseva, VN1
Lopatin, AS1
Deshchekina, MF1
Fadeeva, MA1
Beattie, CW1
Chernov, HI1
Bernard, PS1
Glenny, FH1
Grubnik, VM1
Nerobeev, VD1

Trials

1 trial available for chlorpromazine and Acute Brain Injuries

ArticleYear
Treatment of chronic post-traumatic organic brain syndrome with dextroamphetamine: first reported case.
    The Journal of nervous and mental disease, 1976, Volume: 162, Issue:5

    Topics: Accidents, Traffic; Adult; Amitriptyline; Brain Injuries; Chlorpromazine; Dextroamphetamine; Drug Th

1976

Other Studies

41 other studies available for chlorpromazine and Acute Brain Injuries

ArticleYear
Intravenous migraine therapy in children with posttraumatic headache in the ED.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:5

    Topics: Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Brain Injuries;

2015
[Prevention by chlorpromazine (R.P. 4560) of serious vascular accidents after experimental lesions on the cerebral peduncles].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1954, Volume: 148, Issue:5-6

    Topics: Accidents; Brain Injuries; Cerebral Peduncle; Chlorpromazine; Humans

1954
Notes on a more active treatment of concussion of the brain.
    Folia psychiatrica, neurologica et neurochirurgica Neerlandica, 1954, Volume: 57, Issue:4-5

    Topics: Brain; Brain Concussion; Brain Injuries; Chlorpromazine; Humans; Manipulation, Osteopathic

1954
Effects of centrally acting drugs on two tests of brain damage.
    A.M.A. archives of neurology and psychiatry, 1957, Volume: 77, Issue:3

    Topics: Barbiturates; Brain; Brain Injuries; Central Nervous System Agents; Chlorpromazine; Humans; Lysergic

1957
Effects of centrally acting drugs on two tests of brain damage.
    A.M.A. archives of neurology and psychiatry, 1957, Volume: 77, Issue:3

    Topics: Barbiturates; Brain; Brain Injuries; Central Nervous System Agents; Chlorpromazine; Humans; Lysergic

1957
Effects of centrally acting drugs on two tests of brain damage.
    A.M.A. archives of neurology and psychiatry, 1957, Volume: 77, Issue:3

    Topics: Barbiturates; Brain; Brain Injuries; Central Nervous System Agents; Chlorpromazine; Humans; Lysergic

1957
Effects of centrally acting drugs on two tests of brain damage.
    A.M.A. archives of neurology and psychiatry, 1957, Volume: 77, Issue:3

    Topics: Barbiturates; Brain; Brain Injuries; Central Nervous System Agents; Chlorpromazine; Humans; Lysergic

1957
[Closed craniocerebral injuries and their therapy].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1963, Volume: 34

    Topics: Brain Injuries; Chlorpromazine; Craniocerebral Trauma; Edema; Humans; Skull Fractures; Sorbitol

1963
[Use of neuroplegic and ganglion-blocking drugs in the treatment of craniocerebral injuries].
    Vestnik khirurgii imeni I. I. Grekova, 1962, Volume: 89

    Topics: Bis-Trimethylammonium Compounds; Brain Injuries; Chlorpromazine; Craniocerebral Trauma; Diphenhydram

1962
[CLINICAL ASPECTS OF THE SEQUELAE TO HEAD INJURIES].
    [Chiryo] [Therapy], 1963, Volume: 45

    Topics: Brain Injuries; Cerebral Hemorrhage; Child; Chlordiazepoxide; Chlorpromazine; Craniocerebral Trauma;

1963
THE USE OF DRUG COMBINATIONS IN PEDIATRIC PSYCHIATRY.
    Current therapeutic research, clinical and experimental, 1964, Volume: 6

    Topics: Adolescent; Biomedical Research; Brain; Brain Damage, Chronic; Brain Injuries; Child; Child Behavior

1964
[ON THE TREATMENT OF ERETHISM IN CHILDREN WITH BRAIN DAMAGE].
    Zeitschrift fur arztliche Fortbildung, 1964, Jun-01, Volume: 58

    Topics: Brain; Brain Damage, Chronic; Brain Injuries; Child; Child Behavior Disorders; Chlorpromazine; Drug

1964
[Clinical aspects and therapy of acute psottraumatic psychoses].
    Der Nervenarzt, 1954, Nov-20, Volume: 25, Issue:11

    Topics: Brain; Brain Injuries; Chlorpromazine; Humans; Mental Disorders; Psychotic Disorders

1954
[On the influence of megaphen, nembutal and novocain on spontaneous EEG and bioelectrical response to light stimuli in brain-injured rabbits].
    Deutsche Zeitschrift fur Nervenheilkunde, 1960, Volume: 180

    Topics: Animals; Brain; Brain Injuries; Chlorpromazine; Electroencephalography; Electrophysiological Phenome

1960
[Treatment with small doses of aminazin of remote sequelae of cerebro-cranial injuries].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1960, Volume: 60

    Topics: Brain; Brain Injuries; Chlorpromazine; Humans

1960
The effect of chlorpromazine on the discrimination between intermittent photic stimulation and a steady light in normal and brain-damaged cats.
    Journal of comparative and physiological psychology, 1961, Volume: 54

    Topics: Animals; Brain; Brain Diseases; Brain Injuries; Cats; Chlorpromazine; Learning; Light; Photic Stimul

1961
Reversal of antipsychotic-induced weight gain during quetiapine treatment.
    International clinical psychopharmacology, 2003, Volume: 18, Issue:6

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Brain Injuries; Chlorpromazine; Dibenzothiazepines; Hu

2003
Pharmacological management of Dysautonomia following traumatic brain injury.
    Brain injury, 2004, Volume: 18, Issue:5

    Topics: Adult; Autonomic Nervous System Diseases; Brain Injuries; Case-Control Studies; Chlorpromazine; Fema

2004
[Mechanisms of spreading generalized activation of the cerebral cortex due to a mechanical injury of the latter].
    Biulleten' eksperimental'noi biologii i meditsiny, 1966, Volume: 61, Issue:1

    Topics: Animals; Brain; Brain Injuries; Cerebral Cortex; Chlorpromazine; Electroencephalography; Rabbits; Re

1966
[A case of hyperkinesia caused by unilateral lesion of the medial part of the thalamus in a dog].
    Biulleten' eksperimental'noi biologii i meditsiny, 1966, Volume: 61, Issue:4

    Topics: Animals; Brain Injuries; Chlorpromazine; Dogs; Head; Humans; Hyperkinesis; Movement Disorders; Paras

1966
Effect of ethanol, chlorpromazine and dexamethasone on blood-brain barrier dysfunction to albumin around large cerebral stab wounds.
    Cytobios, 1981, Volume: 31, Issue:122

    Topics: Alcoholic Intoxication; Animals; Blood-Brain Barrier; Brain Injuries; Chlorpromazine; Dexamethasone;

1981
The clinical outcome of patients with severe head injuries, treated with highdose dexamethasone, hyperventilation and barbiturates.
    Neurochirurgia, 1981, Volume: 24, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Brain Injuries; Child; Child, Preschool; Chlorpromazine; Dexam

1981
[Nerve tissue ultrastructure in experimental brain injuries in animals with increased immunobiologic reactivity following treatment with certain desensitizing drugs].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1981, Volume: 81, Issue:5

    Topics: Animals; Aspirin; Autoimmune Diseases; Brain; Brain Edema; Brain Injuries; Chinchilla; Chlorpromazin

1981
Obstetric complications and autoantibodies in schizophrenia.
    Acta psychiatrica Scandinavica, 1995, Volume: 92, Issue:4

    Topics: Adult; Antipsychotic Agents; Autoantibodies; Brain Injuries; Chlorpromazine; Enzyme-Linked Immunosor

1995
Cerebral metabolic rate of oxygen (CMRO2) in the acute phase of brain injury.
    Acta anaesthesiologica Scandinavica, 1978, Volume: 22, Issue:3

    Topics: Adolescent; Adult; Aged; Blood Pressure; Brain; Brain Injuries; Cerebrovascular Circulation; Child;

1978
Chlorpromazine treatment of blood-brain barrier dysfunction. A quantitative and fluorescence microscopical study on small cerebral stab wounds in the rat.
    Acta neuropathologica, 1979, Apr-12, Volume: 46, Issue:1-2

    Topics: Albumins; Animals; Blood-Brain Barrier; Brain Injuries; Cerebral Cortex; Chlorpromazine; Ethanol; Fr

1979
[Clinico-electroencephalographic characteristics of the condition of brain stem systems following surgical and non-surgical brain injury].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1976, Volume: 76, Issue:3

    Topics: Adult; Amphetamine; Anesthesia, General; Autonomic Nervous System; Brain Injuries; Brain Neoplasms;

1976
Fever after traumatic brain injury.
    The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses, 1992, Volume: 24, Issue:2

    Topics: Adult; Body Temperature Regulation; Brain Injuries; Chlorpromazine; Cryotherapy; Decision Making; Fe

1992
[Neurons in the hyperchromic state].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1986, Volume: 86, Issue:7

    Topics: Animals; Autolysis; Brain Injuries; Cell Nucleus; Cerebral Cortex; Chlorpromazine; Chromatin; Male;

1986
Chlorpromazine treatment for neurogenic pulmonary edema.
    Critical care medicine, 1985, Volume: 13, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adult; Brain Diseases; Brain Injuries; Chlorpromazine; Humans; Male; O

1985
Severe head injuries.
    Lancet (London, England), 1968, Mar-23, Volume: 1, Issue:7543

    Topics: Brain Injuries; Chlorpromazine; Shock, Traumatic

1968
The role of monoamines in rotation induced or potentiated by amphetamine after nigral, raphe and mesencephalic reticular lesions in the rat brain.
    Neuropharmacology, 1973, Volume: 12, Issue:3

    Topics: Amines; Amphetamine; Animals; Behavior, Animal; Brain; Brain Injuries; Catalepsy; Cerebral Cortex; C

1973
Unstable fractures in children with acute, severe brain injury.
    Acta orthopaedica Scandinavica, 1974, Volume: 45, Issue:3

    Topics: Accidents, Traffic; Arm Injuries; Brain Injuries; Chlorpromazine; Female; Femoral Fractures; Fractur

1974
Effects of (-) 9 -trans-tetrahydrocannabinol and its selectivity in several models of aggressive behavior.
    Pharmacology, 1973, Volume: 9, Issue:4

    Topics: Aggression; Animals; Behavior, Animal; Brain Injuries; Cannabis; Cats; Chlorpromazine; Dronabinol; E

1973
[Effectiveness of certain therapeutic measures in the acute period of isolated craniocerebral injuries].
    Voenno-meditsinskii zhurnal, 1973, Volume: 10

    Topics: Animals; Autonomic Nerve Block; Body Temperature; Brain; Brain Concussion; Brain Edema; Brain Injuri

1973
Effect of brain lesions and chlorpromazine on accumulation and disappearance of catecholamines formed in vivo from 14 C-tyrosine.
    Acta physiologica Scandinavica, 1972, Volume: 84, Issue:1

    Topics: Animals; Basal Ganglia; Brain Injuries; Carbon Isotopes; Chlorpromazine; Corpus Striatum; Dopamine;

1972
[The diagnostic importance of functional tests of facial skin in closed craniocerebral trauma patients].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1969, Volume: 69, Issue:9

    Topics: Body Temperature; Brain Injuries; Chloroform; Chlorpromazine; Electric Stimulation; Epinephrine; Eth

1969
[Treatment of psychomotor excitations in patients with acute cerebrocranial injuries].
    Khirurgiia, 1969, Volume: 45, Issue:4

    Topics: Brain Injuries; Cerebrospinal Fluid; Chlorpromazine; Female; Humans; Male; Pressure; Psychomotor Dis

1969
[On the treatment of psycopath-like states in children with psychotropic drugs after infectious and traumatic disorders of the central nervous system].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1967, Volume: 67, Issue:10

    Topics: Adolescent; Antidepressive Agents; Antisocial Personality Disorder; Brain Diseases; Brain Injuries;

1967
[Treatment of status epilepticus with the intravenous administration of aminazine].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1968, Volume: 67, Issue:8

    Topics: Adult; Brain Injuries; Chlorpromazine; Epilepsy; Female; Humans; Injections, Intravenous; Male

1968
[Aminazin in the complex treatment of sick newborns].
    Voprosy okhrany materinstva i detstva, 1969, Volume: 14, Issue:1

    Topics: Birth Injuries; Brain Injuries; Central Nervous System Diseases; Chlorpromazine; Humans; Infant; Inf

1969
[Basic clinical syndromes of vital disorders in severe lesions of the skull and brain].
    Vestnik khirurgii imeni I. I. Grekova, 1969, Volume: 102, Issue:1

    Topics: Aminophylline; Bis-Trimethylammonium Compounds; Brain Injuries; Chlorpromazine; Electroencephalograp

1969
Pharmacological alteration of hyper-reactivity in rats with septal and hypothalamic lesions.
    International journal of neuropharmacology, 1969, Volume: 8, Issue:4

    Topics: Aminopyrine; Analgesics; Animals; Behavior, Animal; Brain; Brain Injuries; Cerebral Ventricles; Chlo

1969
[Experience in the treatment of psychomotor excitation with acute cerebrocranial trauma in a rural district hospital].
    Klinicheskaia khirurgiia, 1965, Volume: 5

    Topics: Adult; Brain Injuries; Chlorpromazine; Humans; Male; Reflex, Abnormal; Shock, Traumatic

1965