chlorpromazine has been researched along with Abnormalities, Drug-Induced in 27 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A girl had cleft palate, micrognathia, Wormian bones, congenital heart disease, dislocated hips, absent tibiae, bowed fibulae, preaxial polydactyly of the feet, and abnormal dermal patterns at birth." | 1.25 | Congenital malformations. Cleft palate, congenital heart disease, absent tibiae, and polydactyly. ( Ho, CK; Kaufman, RL; McAlister, WH, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (96.30) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (3.70) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DELERUE, J | 1 |
| O'LEARY, JL | 1 |
| O'LEARY, JA | 1 |
| GOLDMAN, AS | 2 |
| YAKOVAC, WC | 1 |
| DOERING, GK | 1 |
| HOSSFELD, C | 1 |
| EYAL-GILADI, H | 1 |
| EYAL, Z | 1 |
| ESHEL, S | 1 |
| RAVINA, JH | 1 |
| Ramkisson, R | 1 |
| Campbell, M | 1 |
| Agius, M | 1 |
| Hoffeld, DR | 1 |
| Webster, RL | 1 |
| McNew, J | 1 |
| Rise, A | 1 |
| Ho, CK | 1 |
| Kaufman, RL | 1 |
| McAlister, WH | 1 |
| Singh, S | 1 |
| Padmanabhan, R | 1 |
| Vargas, GC | 1 |
| Pildes, RS | 1 |
| Vidyasagar, D | 1 |
| Keith, LG | 1 |
| Yu, JF | 1 |
| Yang, YS | 1 |
| Wang, WY | 1 |
| Xiong, GX | 1 |
| Chen, MS | 1 |
| Fratta, ID | 1 |
| Gross, A | 1 |
| Thiele, K | 1 |
| Schuler, WA | 1 |
| von Schlichtegroll, A | 1 |
| Shapiro, IuL | 1 |
| Vaĭntrub, MIa | 1 |
| Grinberg, KN | 1 |
| Zhurkov, VS | 1 |
| Kiriushchenkov, AP | 1 |
| Smol'nikova, NM | 1 |
| Skosyreva, AM | 1 |
| Farkas, G | 4 |
| Rothstein, P | 1 |
| Gould, JB | 1 |
| Vichi, F | 1 |
| Roizin, L | 1 |
| Kaufman, MA | 1 |
| Gold, G | 1 |
| Iyengar, VK | 1 |
| Liu, JC | 1 |
| Keoseian, S | 1 |
| Beall, JR | 1 |
| Aoki, FY | 1 |
| Ruedy, J | 1 |
| Zucconi, G | 1 |
| Pannuti, P | 1 |
| Pap, AG | 1 |
| Tarakhovskiĭ, ML | 1 |
2 reviews available for chlorpromazine and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
[Teratogenic and mutagenic effects of anticonvulsive and psychotropic drugs (review of the literature)].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Anticonvulsants; Antidepressive Agent | 1972 |
[Neuroleptics in experimental teratogenesis].
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Chlorpromazine; Fluphenazine; Haloperidol; Mice; | 1968 |
25 other studies available for chlorpromazine and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
[TERATOGENIC ACTION OF DRUGS IN THE PREGNANT WOMAN].
Topics: Abnormalities, Drug-Induced; Antineoplastic Agents; Avitaminosis; Chlorpromazine; Cortisone; Female; | 1963 |
NONTHALIDOMIDE ECTROMELIA: REPORT OF A CASE.
Topics: Abnormalities, Drug-Induced; Chlorpromazine; Ectromelia; Meclizine; Pregnancy; Toxicology | 1964 |
PREVENTION OF SALICYLATE TERATOGENICITY IN IMMOBILIZED RATS BY CERTAIN CENTRAL NERVOUS SYSTEM DEPRESSANTS.
Topics: Abnormalities, Drug-Induced; Central Nervous System Depressants; Chlorpromazine; Fetal Death; Immobi | 1964 |
[ON THE HAZARDS OF AN EXAGGERATED FEAR OF DRUGS IN PREGNANCY. STUDIES ON THE INFLUENCE OF HYPEREMESIS GRAVIDARUM AS WELL AS VARIOUS ANTIEMETICS (MECLIZINE, PHENOTHIAZINE DERIVATIVES) ON THE INCIDENCE OF MALFORMATIONS].
Topics: Abnormalities, Drug-Induced; Antiemetics; Antipsychotic Agents; Cerium; Chlorpromazine; Congenital A | 1964 |
A MICROSCOPIC STUDY OF CHLORPROMAZINE (LARGACTIL) TREATED AXOLOTL LARVAE.
Topics: Abnormalities, Drug-Induced; Ambystoma; Ambystoma mexicanum; Animals; Blood Vessels; Chlorpromazine; | 1964 |
[HAZARDOUS THERAPEUTICS IN THE PREGNANT WOMAN].
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Bacterial Ag | 1964 |
The clinical dilemma--prescribing in pregnancy.
Topics: Abnormalities, Drug-Induced; Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Chlorpr | 2008 |
Adverse effects on offspring of tranquilizing drugs during pregnancy.
Topics: Abnormalities, Drug-Induced; Animals; Avoidance Learning; Behavior, Animal; Chlorpromazine; Extincti | 1967 |
[Neuroleptics].
Topics: Abnormalities, Drug-Induced; Antipsychotic Agents; Butyrophenones; Chlorpromazine; Female; Fluphenaz | 1976 |
Congenital malformations. Cleft palate, congenital heart disease, absent tibiae, and polydactyly.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Chloramines; Chlorpromazine; Cleft Palate; Dip | 1975 |
Teratogenic effects of chlorpromazine hydrochloride in rat foetuses.
Topics: Abnormalities, Drug-Induced; Animals; Chlorpromazine; Female; Pregnancy; Rats; Time Factors | 1978 |
Effect of maternal heroin addiction on 67 liveborn neonates. Withdrawal symptoms, small body size, and small head circumference were frequent findings.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Birth Weight; Blood Glucose; Cephalomet | 1975 |
Mutagenicity and teratogenicity of chlorpromazine and scopolamine.
Topics: Abnormalities, Drug-Induced; Animals; Chlorpromazine; Chromosome Aberrations; Female; Limb Deformiti | 1988 |
Nicotinamide deficiency and thalidomide: potential teratogenic disturbances in Long-Evans rats.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Animal Feed; Animals; Birth Weight; Chlorproma | 1969 |
[2-chlor-4-azaphenthiazine. Synthesis and pharmacological properties of cloxypendyl].
Topics: Abnormalities, Drug-Induced; Acetylcholine; Animals; Autonomic Agents; Autonomic Nervous System; Blo | 1968 |
[The effect of aminazine and chlorazicin on early embryogenesis].
Topics: Abnormalities, Drug-Induced; Animals; Chlorpromazine; Female; Fetal Death; Gestational Age; In Vitro | 1972 |
Developmental defects: a final common pathway of teratogenicity?
Topics: Abnormalities, Drug-Induced; Animals; Autonomic Nervous System; Bicarbonates; Chlorpromazine; Embryo | 1973 |
[Proceedings: Is hemorrhage in early pregnancy and its drug therapy an increased risk of teratogenesis?].
Topics: Abnormalities, Drug-Induced; Abortion, Threatened; Allyl Compounds; Aminopyrine; Chlordiazepoxide; C | 1973 |
Born with a habit. Infants of drug-addicted mothers.
Topics: Abnormalities, Drug-Induced; Adult; Age Factors; Barbiturates; Camphor; Chlorpromazine; Codeine; Dia | 1974 |
[Teratogenic effects of hyperemesis gravidarum and of the customary drugs used in its therapy].
Topics: Abnormalities, Drug-Induced; Chlorpromazine; Clubfoot; Congenital Abnormalities; Female; Heart Defec | 1971 |
A multidisciplinary investigation of the phenothiazines.
Topics: Abnormalities, Drug-Induced; Animals; Brain; Cardiovascular System; Chlorpromazine; Digestive System | 1966 |
A teratogenic study of chlorpromazine, orphenadrine, perphenzaine, and LSD-25 in rats.
Topics: Abnormalities, Drug-Induced; Animals; Birth Weight; Chlorpromazine; Embryo Implantation; Evaluation | 1972 |
Severe lithium intoxication: management without dialysis and report of a possible teratogenic effect of lithium.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Bipolar Disorder; Chlorpromazine; Dose-Response | 1971 |
[Hyperemesis in the first trimester of pregnancy: causes and therapeutic advances].
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Adult; Chlorpromazine; Female; Humans; Hyperem | 1967 |
[Effect of several drugs on the fetus].
Topics: Abnormalities, Drug-Induced; Aminopyrine; Animals; Aspirin; Benzimidazoles; Chlorpromazine; Cortison | 1967 |