chlorpromazine has been researched along with Abdominal Migraine in 34 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlorpromazine, given intravenously, is a useful agent in the treatment of acute migraine headaches." | 7.68 | Response of non-migrainous headaches to chlorpromazine. ( Barclay, CL; Montoya, D; Seland, TP; Shuaib, A; Thomas, HG, 1990) |
| " Compared to other active drugs, it only showed a lower significant effect compared with granisetron regarding headache change while it showed significantly higher effects only with placebo in both rescue medication needs and headache-free symptoms and valproate in only rescue medication need." | 5.41 | The efficacy and safety of metoclopramide in relieving acute migraine attacks compared with other anti-migraine drugs: a systematic review and network meta-analysis of randomized controlled trials. ( Abd-ElGawad, M; Abdelhay, HM; Abdelmonem, H; Abdelwadoud, GT; Ahmed, AE; Al-Dardery, NM; Alhosini, ANM; Kamel, MA; Mohamed, SW, 2023) |
| "Chlorpromazine, given intravenously, is a useful agent in the treatment of acute migraine headaches." | 3.68 | Response of non-migrainous headaches to chlorpromazine. ( Barclay, CL; Montoya, D; Seland, TP; Shuaib, A; Thomas, HG, 1990) |
| "Migraine is a common, incapacitating neurological condition." | 3.01 | A prospective, randomized, double-blind trial of intravenous chlorpromazine versus intravenous prochlorperazine for the treatment of acute migraine in adults presenting to the emergency department. ( Bourke, EM; Greene, SL; Harding, AM; Hodgson, SE; Taylor, DM, 2021) |
| "Sixty patients with migraine with aura and 68 patients with migraine without aura were assigned at random to receive IV 0." | 2.70 | Intravenous chlorpromazine in the emergency department treatment of migraines: a randomized controlled trial. ( Bigal, ME; Bordini, CA; Speciali, JG, 2002) |
| "The chlorpromazine was repeated every 15 minutes as needed up to a total of three doses." | 2.66 | Comparative efficacy of chlorpromazine and meperidine with dimenhydrinate in migraine headache. ( Baggoley, CJ; Lane, PL; McLellan, BA, 1989) |
| "Eighteen patients experienced orthostatic hypotension following injection." | 2.65 | Parenteral chlorpromazine treatment of migraine. ( Iserson, KV, 1983) |
| "Recent advances in migraine therapy include the recognition of analgesic or ergotamine abuse as a cause of chronic daily migraine, the introduction of effective non-narcotic drugs such as chlorpromazine, dihydroergotamine and corticosteroids for the treatment of intractable migraine attacks, the increased number of beta-blockers now recognized as effective prophylactic agents and the introduction of calcium-channel blockers for prophylaxis." | 2.37 | Migraine. ( Edmeads, JG, 1988) |
| "In paediatric migraine, ibuprofen, acetaminophen and triptans are safe, effective therapies but there is scant paediatric data informing second-line emergency treatment." | 1.72 | Intravenous chlorpromazine for acute paediatric migraine. ( Babl, FE; Hill, A; Löllgen, RM; Mackay, MT; Palmer, GM, 2022) |
| "Intravenous migraine therapy reduces PTH pain scores for children presenting within 14 days after mTBI." | 1.42 | Intravenous migraine therapy in children with posttraumatic headache in the ED. ( Byczkowski, T; Chan, S; Kurowski, B; Timm, N, 2015) |
| "Chlorpromazine was included as an option for treatment at our institution during this shortage, although limited data exist on the effectiveness in children." | 1.40 | Chlorpromazine for the treatment of migraine in a pediatric emergency department. ( Kanis, JM; Timm, NL, 2014) |
| "Consecutive 21 patients with status migrainosus were received intra-venous chlorpromazine (maximum 25mg) with fluid treatment and their results were documented." | 1.40 | Intra-venous chlorpromazine with fluid treatment in status migrainosus. ( Benli, EM; Dinc, A; Gokce, M; Tuncel, D; Utku, U, 2014) |
| "In 1996, 1254 patients were treated for headache and 64 of them required hospitalization." | 1.30 | [Headache treatment in an emergency unit of the city of Ribeirão Preto, Brazil]. ( Bigal, ME; Bordini, CA; Speciali, JG, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (50.00) | 18.7374 |
| 1990's | 7 (20.59) | 18.2507 |
| 2000's | 3 (8.82) | 29.6817 |
| 2010's | 4 (11.76) | 24.3611 |
| 2020's | 3 (8.82) | 2.80 |
| Authors | Studies |
|---|---|
| Löllgen, RM | 1 |
| Babl, FE | 1 |
| Mackay, MT | 1 |
| Hill, A | 1 |
| Palmer, GM | 1 |
| Abdelmonem, H | 1 |
| Abdelhay, HM | 1 |
| Abdelwadoud, GT | 1 |
| Alhosini, ANM | 1 |
| Ahmed, AE | 1 |
| Mohamed, SW | 1 |
| Al-Dardery, NM | 1 |
| Abd-ElGawad, M | 1 |
| Kamel, MA | 1 |
| Hodgson, SE | 1 |
| Harding, AM | 1 |
| Bourke, EM | 1 |
| Taylor, DM | 1 |
| Greene, SL | 1 |
| Khazaei, M | 1 |
| Hosseini Nejad Mir, N | 1 |
| Yadranji Aghdam, F | 1 |
| Taheri, M | 1 |
| Ghafouri-Fard, S | 1 |
| Kanis, JM | 1 |
| Timm, NL | 1 |
| Utku, U | 1 |
| Gokce, M | 1 |
| Benli, EM | 1 |
| Dinc, A | 1 |
| Tuncel, D | 1 |
| Chan, S | 1 |
| Kurowski, B | 1 |
| Byczkowski, T | 1 |
| Timm, N | 1 |
| Bigal, ME | 2 |
| Bordini, CA | 2 |
| Speciali, JG | 2 |
| FEJER, A | 2 |
| Herman, LY | 1 |
| Logan, P | 1 |
| Loga, P | 1 |
| Lewis, D | 1 |
| Iserson, KV | 1 |
| Fozard, JR | 1 |
| Cameron, JD | 1 |
| Lane, PL | 3 |
| Speechley, M | 1 |
| Kelly, AM | 1 |
| Ardagh, M | 1 |
| Curry, C | 1 |
| D'Antonio, J | 1 |
| Zebic, S | 1 |
| Fisher, H | 1 |
| Bell, R | 1 |
| Montoya, D | 2 |
| Shuaib, A | 2 |
| Lee, MA | 1 |
| Raskin, NH | 1 |
| Barclay, CL | 1 |
| Seland, TP | 1 |
| Thomas, HG | 1 |
| McLellan, BA | 1 |
| Baggoley, CJ | 1 |
| Edmeads, JG | 1 |
| Mariani, PJ | 1 |
| McEwen, JI | 1 |
| O'Connor, HM | 1 |
| Dinsdale, HB | 1 |
| Ross, R | 1 |
| Nader, S | 1 |
| Tulloch, B | 1 |
| Blair, C | 1 |
| Vydelingum, N | 1 |
| Fraser, TR | 1 |
| Horrobin, DF | 2 |
| Cahen, RL | 1 |
| Hertrich, O | 1 |
| Wieck, HH | 1 |
| Hilton, BP | 1 |
5 reviews available for chlorpromazine and Abdominal Migraine
| Article | Year |
|---|---|
The efficacy and safety of metoclopramide in relieving acute migraine attacks compared with other anti-migraine drugs: a systematic review and network meta-analysis of randomized controlled trials.
Topics: Chlorpromazine; Granisetron; Headache; Humans; Ketorolac; Metoclopramide; Migraine Disorders; Nausea | 2023 |
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Chlorpromazine in migraine.
Topics: Chlorpromazine; Dopamine Antagonists; Emergency Medicine; Evidence-Based Medicine; Humans; Migraine | 2007 |
Basic mechanisms of antimigraine drugs.
Topics: Amitriptyline; Animals; Chlorpromazine; Humans; Methysergide; Metoclopramide; Migraine Disorders; Pr | 1982 |
Modern pharmacotherapy of migraine.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Chlorpromazine; Dihydroergotamine; Ergotamine; | 1990 |
Migraine.
Topics: Acute Disease; Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Analgesics; Calcium Channel Blo | 1988 |
10 trials available for chlorpromazine and Abdominal Migraine
| Article | Year |
|---|---|
A prospective, randomized, double-blind trial of intravenous chlorpromazine versus intravenous prochlorperazine for the treatment of acute migraine in adults presenting to the emergency department.
Topics: Administration, Intravenous; Adolescent; Adult; Aged; Australia; Chlorpromazine; Dopamine Antagonist | 2021 |
Effectiveness of intravenous dexamethasone, metoclopramide, ketorolac, and chlorpromazine for pain relief and prevention of recurrence in the migraine headache: a prospective double-blind randomized clinical trial.
Topics: Administration, Intravenous; Adult; Analgesics; Chlorpromazine; Dexamethasone; Double-Blind Method; | 2019 |
Intravenous chlorpromazine in the emergency department treatment of migraines: a randomized controlled trial.
Topics: Chlorpromazine; Dopamine Antagonists; Double-Blind Method; Emergency Service, Hospital; Humans; Inje | 2002 |
Parenteral chlorpromazine treatment of migraine.
Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Female; Humans; Hypotension, Orthostati | 1983 |
Intravenous chlorpromazine vs intravenous metoclopramide in acute migraine headache.
Topics: Acute Disease; Adolescent; Adult; Aged; Chlorpromazine; Dopamine Antagonists; Double-Blind Method; E | 1995 |
Intravenous chlorpromazine versus intramuscular sumatriptan for acute migraine.
Topics: Adolescent; Adult; Aged; Australia; Chlorpromazine; Cross-Over Studies; Dopamine Antagonists; Emerge | 1997 |
A comparative trial of three agents in the treatment of acute migraine headache.
Topics: Adult; Chlorpromazine; Dihydroergotamine; Emergencies; Follow-Up Studies; Humans; Infusions, Intrave | 1990 |
Comparative efficacy of chlorpromazine and meperidine with dimenhydrinate in migraine headache.
Topics: Adult; Chlorpromazine; Dimenhydrinate; Double-Blind Method; Drug Therapy, Combination; Female; Human | 1989 |
Treatment of migraine with intramuscular chlorpromazine.
Topics: Adult; Chlorpromazine; Double-Blind Method; Drug Evaluation; Female; Humans; Injections, Intramuscul | 1987 |
Is prolactin involved in precipitating migraine?
Topics: Administration, Oral; Blood Glucose; Chlorpromazine; Drug Interactions; Ergot Alkaloids; Ethanol; Fa | 1974 |
19 other studies available for chlorpromazine and Abdominal Migraine
| Article | Year |
|---|---|
Intravenous chlorpromazine for acute paediatric migraine.
Topics: Acetaminophen; Child; Chlorpromazine; Emergency Service, Hospital; Humans; Ibuprofen; Migraine Disor | 2022 |
Chlorpromazine for the treatment of migraine in a pediatric emergency department.
Topics: Adolescent; Child; Chlorpromazine; Cohort Studies; Dopamine Antagonists; Emergency Service, Hospital | 2014 |
Intra-venous chlorpromazine with fluid treatment in status migrainosus.
Topics: Administration, Intravenous; Adult; Antiemetics; Chlorpromazine; Cohort Studies; Female; Fluid Thera | 2014 |
Intravenous migraine therapy in children with posttraumatic headache in the ED.
Topics: Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Brain Injuries; | 2015 |
[The treatment of vascular headache with Hirepin].
Topics: Chlorpromazine; Histamine; Migraine Disorders; Promethazine; Reserpine; Vascular Headaches | 1962 |
HIREPIN TREATMENT OF VASCULAR HEADACHE.
Topics: Chlorpromazine; Migraine Disorders; Promethazine; Reserpine; Vascular Headaches | 1963 |
The efficacy of a safe, effective non-narcotic treatment of migraine headache.
Topics: Chlorpromazine; Dopamine Antagonists; Humans; Migraine Disorders | 2003 |
Parenteral chlorpromazine for migraine.
Topics: Chlorpromazine; Humans; Injections, Intravenous; Migraine Disorders | 1984 |
Migraine research methods.
Topics: Analgesics, Opioid; Butorphanol; Chlorpromazine; Dopamine Antagonists; Humans; Migraine Disorders; R | 1997 |
[Headache treatment in an emergency unit of the city of Ribeirão Preto, Brazil].
Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroida | 1999 |
Response of non-migrainous headaches to chlorpromazine.
Topics: Adult; Cerebral Hemorrhage; Chlorpromazine; Diagnosis, Differential; Headache; Humans; Male; Middle | 1990 |
Adverse reactions to chlorpromazine in the treatment of migraine.
Topics: Adult; Akathisia, Drug-Induced; Chlorpromazine; Female; Humans; Migraine Disorders | 1988 |
Intravenous chlorpromazine--preliminary results in acute migraine.
Topics: Acute Disease; Adult; Aged; Chlorpromazine; Drug Evaluation; Humans; Injections, Intravenous; Middle | 1985 |
Letter: Prolactin and migraine.
Topics: Bromine; Chlorpromazine; Drug Therapy, Combination; Ergot Alkaloids; Female; Half-Life; Humans; Inje | 1974 |
Letter: Prolactin and migraine.
Topics: Chlorpromazine; Ethanol; Female; Humans; Migraine Disorders; Prolactin | 1974 |
Emetic effect of biogenic amines.
Topics: 5-Hydroxytryptophan; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Brain; Catecholamines; | 1970 |
[Neuroleptics, thymoleptics and tranquilizers in neurological therapy].
Topics: Basal Ganglia Diseases; Chlordiazepoxide; Chlorpromazine; Diazepam; Epilepsy; Extrapyramidal Tracts; | 1969 |
[Headache. Diagnosis and therapy in general practice].
Topics: Carbamazepine; Chlorpromazine; Depression; Ergotamine; Giant Cell Arteritis; Headache; Humans; Migra | 1974 |
Effects of reserpine and chlorpromazine on 5-hydroxytryptamine uptake of platelets from migrainous and control subjects.
Topics: Blood Platelets; Carbon Radioisotopes; Cell Membrane; Chlorpromazine; Humans; Migraine Disorders; Pl | 1974 |