chlorpromazine has been researched along with 2019 Novel Coronavirus Disease in 12 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlorpromazine (CPZ) is a phenothiazine derivative widely used in clinical routine in the treatment of acute and chronic psychoses." | 1.56 | [Repurposing of chlorpromazine in COVID-19 treatment: the reCoVery study]. ( Attali, D; Blatzer, M; Cachia, A; Chrétien, F; Gaillard, R; Petit, AC; Plaze, M; Simon-Loriere, E; Vinckier, F, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 12 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pillaiyar, T | 1 |
| Wendt, LL | 1 |
| Manickam, M | 1 |
| Easwaran, M | 1 |
| Plaze, M | 2 |
| Attali, D | 2 |
| Petit, AC | 2 |
| Blatzer, M | 2 |
| Simon-Loriere, E | 2 |
| Vinckier, F | 2 |
| Cachia, A | 2 |
| Chrétien, F | 2 |
| Gaillard, R | 2 |
| Glebov, OO | 1 |
| Nitulescu, GM | 1 |
| Paunescu, H | 1 |
| Moschos, SA | 1 |
| Petrakis, D | 1 |
| Nitulescu, G | 1 |
| Ion, GND | 1 |
| Spandidos, DA | 1 |
| Nikolouzakis, TK | 1 |
| Drakoulis, N | 1 |
| Tsatsakis, A | 1 |
| Stip, E | 1 |
| Han, YJ | 1 |
| Ren, ZG | 1 |
| Li, XX | 1 |
| Yan, JL | 1 |
| Ma, CY | 1 |
| Wu, DD | 1 |
| Ji, XY | 1 |
| Weston, S | 1 |
| Coleman, CM | 1 |
| Haupt, R | 1 |
| Logue, J | 1 |
| Matthews, K | 1 |
| Li, Y | 1 |
| Reyes, HM | 1 |
| Weiss, SR | 1 |
| Frieman, MB | 1 |
| Otręba, M | 1 |
| Kośmider, L | 1 |
| Rzepecka-Stojko, A | 1 |
| Dorgalaleh, A | 1 |
| Dabbagh, A | 1 |
| Tabibian, S | 1 |
| Bahraini, M | 1 |
| Rafieemehr, H | 1 |
| Blaess, M | 1 |
| Kaiser, L | 1 |
| Sommerfeld, O | 1 |
| Csuk, R | 1 |
| Deigner, HP | 1 |
| Ikitimur, H | 1 |
| Borku Uysal, B | 1 |
| Ikitimur, B | 1 |
| Umihanic, S | 1 |
| Smajic, J | 1 |
| Jahic, R | 1 |
| Olcay, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| "Cardiac Transfer of SARS-CoV-2 Spike Protein Circulation Techniques - Medicine Induced Hemodialysis on Vaccinated Immune Attacks"[NCT05711810] | Phase 4 | 1 participants (Actual) | Interventional | 2023-01-02 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for chlorpromazine and 2019 Novel Coronavirus Disease
| Article | Year |
|---|---|
The recent outbreaks of human coronaviruses: A medicinal chemistry perspective.
Topics: Antiviral Agents; Chemistry, Pharmaceutical; COVID-19; Disease Outbreaks; Drug Repositioning; Humans | 2021 |
Understanding SARS-CoV-2 endocytosis for COVID-19 drug repurposing.
Topics: Alveolar Epithelial Cells; Amiloride; Antiviral Agents; Caveolae; Chlorpromazine; Clathrin-Coated Ve | 2020 |
Comprehensive analysis of drugs to treat SARS‑CoV‑2 infection: Mechanistic insights into current COVID‑19 therapies (Review).
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Betacoronavirus; Bromhexin | 2020 |
Advances and challenges in the prevention and treatment of COVID-19.
Topics: Amides; Antibodies, Monoclonal; Antiviral Agents; Betacoronavirus; Chloroquine; Chlorpromazine; Coro | 2020 |
Antiviral activity of chlorpromazine, fluphenazine, perphenazine, prochlorperazine, and thioridazine towards RNA-viruses. A review.
Topics: Animals; Antipsychotic Agents; Antiviral Agents; Betacoronavirus; Chlorpromazine; Coronavirus Infect | 2020 |
1 trial available for chlorpromazine and 2019 Novel Coronavirus Disease
| Article | Year |
|---|---|
Repurposing chlorpromazine to treat COVID-19: The reCoVery study.
Topics: Antiviral Agents; Anxiety; Betacoronavirus; Blood-Brain Barrier; Chlorpromazine; Clathrin-Coated Ves | 2020 |
6 other studies available for chlorpromazine and 2019 Novel Coronavirus Disease
| Article | Year |
|---|---|
[Repurposing of chlorpromazine in COVID-19 treatment: the reCoVery study].
Topics: Antiviral Agents; Betacoronavirus; Biomarkers; Blood-Brain Barrier; Chlorpromazine; Clinical Trials, | 2020 |
Psychiatry and COVID-19: The Role of Chlorpromazine.
Topics: Antipsychotic Agents; Antiviral Agents; Chlorpromazine; Clathrin; Coronavirus Infections; COVID-19; | 2020 |
Broad Anti-coronavirus Activity of Food and Drug Administration-Approved Drugs against SARS-CoV-2
Topics: A549 Cells; Animals; Antiviral Agents; Betacoronavirus; Chloroquine; Chlorpromazine; Coronavirus Inf | 2020 |
Persistent hiccups in a patient with mild congenital factor V deficiency and COVID-19; clinical and laboratory finding of a rare bleeding disorder.
Topics: Chlorpromazine; COVID-19; COVID-19 Drug Treatment; Factor V Deficiency; Hematologic Tests; Hemorrhag | 2021 |
Drugs, Metabolites, and Lung Accumulating Small Lysosomotropic Molecules: Multiple Targeting Impedes SARS-CoV-2 Infection and Progress to COVID-19.
Topics: Antiviral Agents; Chlorpromazine; COVID-19; COVID-19 Drug Treatment; Cytokine Release Syndrome; Drug | 2021 |
Case Report: Two Cases of Persistent Hiccups Complicating COVID-19.
Topics: Aged; Chlorpromazine; COVID-19; Hiccup; Humans; Male; Middle Aged; SARS-CoV-2 | 2021 |