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chlorphentermine and Lipidoses

chlorphentermine has been researched along with Lipidoses in 70 studies

*Lipidoses: Conditions characterized by abnormal lipid deposition due to disturbance in lipid metabolism, such as hereditary diseases involving lysosomal enzymes required for lipid breakdown. They are classified either by the enzyme defect or by the type of lipid involved. [MeSH]

Research

Studies (70)

TimeframeStudies, this research(%)All Research%
pre-199061 (87.14)18.7374
1990's7 (10.00)18.2507
2000's0 (0.00)29.6817
2010's2 (2.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Glen, RC; Lowe, R; Mitchell, JB1
Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T1
Kacew, S; Narbaitz, R1
Lüllmann-Rauch, R; Stoermer, B1
Christensen, EI; Lüllmann-Rauch, R; Maunsbach, AB1
Bichler, E1
Albert, C; Lüllmann-Rauch, R1
Drenckhahn, D; Jacobi, B; Lüllmann-Rauch, R1
Castranova, V; Reasor, MJ1
Gairola, C; Matulionis, DH; Reasor, MJ1
Lüllmann-Rauch, R6
Reasor, MJ3
Ferin, J1
Lüllmann, H; Lüllmann-Rauch, R; Mösinger, EU1
Kacew, S; Narbaitz, R; Ruddick, JA; Villeneuve, DC1
Hostetler, KY; Matsuzawa, Y1
Reasor, MJ; Walker, ER1
McNulty, MJ; Reasor, MJ1
Koshut, RA; McNulty, MJ; Reasor, MJ; Trush, MA1
Frisch, W; Lüllmann-Rauch, R1
Bichler, E; Spoendlin, H1
Beard, TL; Kacew, S; McCloud, CM; Reasor, MJ1
Bredehorn, T; Duncker, G1
Bichler, E; Daxecker, F1
Geist, SH; Lüllmann-Rauch, R1
Kirk, RG; Lee, P; Reasor, MJ1
Bredehorn, T; Duncker, GI1
Seiler, KU; Thiel, HJ; Wassermann, O1
Lüllmann, H; Mösinger, EU1
Lüllmann-Rauch, R; Reil, GH2
Lüllmann-Rauch, B1
Drenckhahn, D3
Buchheim, W; Drenckhahn, D; Lüllmann-Rauch, R1
Drenckhahn, D; Lüllmann-Rauch, R3
Castranova, V; Koshut, RA; Reasor, MJ1
Blaschke, G; Seydel, JK; Wassermann, O1
Drenckhahn, D; Kleine, L; Lüllmann-Rauch, R1
Karabelnik, D; Zbinden, G2
Gloster, J; Harris, P; Hasleton, P; Heath, D1
Kacew, S; Reasor, MJ1
Kacew, S3
Bendayan, M; Coulombe, PA1
Burmester, J; Hanpft, R; Kröplin, K; Lüllmann-Rauch, R; Patten, M1
Lüllmann-Rauch, R; Watermann, D1
Born, GS; DeNicola, DB; Hastings, CE; Kessler, WV; Rebar, AH; Turek, JJ1
Heyneman, CA; Reasor, MJ2
Lüllmann Rauch, R; Reil, GH1
Lüllmann, H; Lüllmann-Rauch, R; Wassermann, O2
Schmien, R; Seiler, KU; Wassermann, O1
Lüllmann-Rauch, R; Reil, GH; Rossen, E; Seiler, KU1
Lüllmann, H; Lüllmann-Rauch, R; Reil, GH1
Anzil, AP; Blinzinger, K; Herrlinger, H1
Lüllmann-Rauch, R; Pietschmann, N1

Reviews

5 review(s) available for chlorphentermine and Lipidoses

ArticleYear
Experimentally induced lipidosis in rat retinal pigment epithelium. A brief review.
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1981, Volume: 215, Issue:4

    Topics: Amiodarone; Animals; Chloroquine; Chlorphentermine; Imipramine; Lipidoses; Microscopy, Electron; Perhexiline; Pigment Epithelium of Eye; Rats

1981
Drug-induced lipidosis and the alveolar macrophage.
    Toxicology, 1981, Volume: 20, Issue:1

    Topics: Animals; Chlorphentermine; Humans; Lipid Peroxides; Lipidoses; Macrophages; Mixed Function Oxygenases; Phagocytosis; Pharmaceutical Preparations; Phospholipids; Pulmonary Alveoli; Rats

1981
Drug-induced experimental lipidosis in the nervous system.
    Neuroscience, 1979, Volume: 4, Issue:6

    Topics: Animals; Axons; Brain; Chlorphentermine; Cricetinae; Disease Models, Animal; Hypothalamo-Hypophyseal System; Lipidoses; Mice; Neuroglia; Neurons; Rabbits; Rats; Sense Organs

1979
[Drug-induced phospholipid storage disease].
    Deutsche medizinische Wochenschrift (1946), 1973, Aug-31, Volume: 98, Issue:35

    Topics: Adrenal Gland Diseases; Amitriptyline; Animals; Anticholesteremic Agents; Appetite Depressants; Body Weight; Cardiomyopathies; Chemical Phenomena; Chemistry; Chloroquine; Chlorphentermine; Drug Interactions; Female; Fenfluramine; Humans; Iprindole; Lipidoses; Lung Diseases; Lysosomes; Male; Phospholipids; Piperazines; Rats; Testicular Diseases; Thyroid Diseases; Triparanol

1973
Drug-induced phospholipidosis.
    German medicine, 1973,Winter, Volume: 3, Issue:3-4

    Topics: Animals; Anticholesteremic Agents; Appetite Depressants; Chlorphentermine; Chromatography, Gel; Chromatography, Thin Layer; Corpus Luteum; Drug Interactions; Female; Inclusion Bodies; Leydig Cells; Lipidoses; Liver; Lung; Lymphocytes; Macrophages; Male; Phospholipids; Psychotropic Drugs; Pulmonary Alveoli; Spectrum Analysis

1973

Other Studies

65 other study(ies) available for chlorphentermine and Lipidoses

ArticleYear
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics

2012
The effect of phenobarbital on chlorphentermine-induced lipidosis-like alterations in renal tissue of adult and newborn rats.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1981, Volume: 36, Issue:1

    Topics: Animals; Animals, Newborn; Chlorphentermine; Drug Interactions; Kidney Diseases; Lipidoses; Male; Phenobarbital; Rats

1981
Generalized lipidosis in newborn rats and Guinea pigs induced during prenatal development by administration of amphiphilic drugs to pregnant animals.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1982, Volume: 39, Issue:1

    Topics: Adrenal Glands; Animals; Chloroquine; Chlorphentermine; Female; Guinea Pigs; Hypothalamus; Kidney; Lipidoses; Liver; Lung; Maternal-Fetal Exchange; Microscopy, Electron; Phentermine; Piperazines; Pituitary Gland; Pregnancy; Rats; Rats, Inbred Strains; Spinal Cord; Spleen

1982
Renal lysosomal protein digestion in experimental lipidosis.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1983, Volume: 43, Issue:3

    Topics: Animals; Autoradiography; Chlorphentermine; Iodine Radioisotopes; Kidney Tubules, Proximal; Lipidoses; Lysosomes; Male; Microscopy, Electron; Muramidase; Rats; Rats, Inbred Strains

1983
[Chlorphentermine-induced lipidosis of the cochlea and the cochlear nucleus].
    Laryngologie, Rhinologie, Otologie, 1983, Volume: 62, Issue:11

    Topics: Animals; Chlorphentermine; Cochlea; Hair Cells, Auditory, Inner; Inclusion Bodies; Labyrinth Diseases; Lipidoses; Male; Microscopy, Electron; Neurons; Phentermine; Phospholipids; Rats; Rats, Inbred Strains

1983
Ultrastructural alterations in peripheral nerve trunks of rats subchronically treated with chlorphentermine or perhexiline.
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:1

    Topics: Animals; Chlorphentermine; Female; Lipidoses; Male; Perhexiline; Peripheral Nerves; Phentermine; Piperidines; Rats; Rats, Inbred Strains; Schwann Cells

1983
Corneal lipidosis in rats treated with amphiphilic cationic drugs.
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:6

    Topics: Animals; Cations; Chloroquine; Chlorphentermine; Corneal Diseases; Female; Iprindole; Lipidoses; Male; Quinacrine; Rats; Rats, Inbred Strains; Tamoxifen

1983
Recovery from chlorphentermine-induced phospholipidosis in rat alveolar macrophages: biochemical and cellular features.
    Experimental and molecular pathology, 1981, Volume: 35, Issue:3

    Topics: Acetylglucosaminidase; Animals; beta-Galactosidase; Chlorphentermine; Lipidoses; Lysosomes; Macrophages; Male; Mannosidases; Phentermine; Phospholipids; Pulmonary Alveoli; Rats

1981
Chlorphentermine-induced alterations in the lungs of vitamin E-deficient and supplemented rats: 1. Biochemical and morphometric analysis of the pulmonary response.
    Experimental and molecular pathology, 1983, Volume: 38, Issue:3

    Topics: Animals; Chlorphentermine; Foam Cells; Hemolysis; Lipid Peroxides; Lipidoses; Lung; Lung Diseases; Male; Phentermine; Phospholipids; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Vitamin E; Vitamin E Deficiency

1983
Alveolar macrophage mediated pulmonary clearance suppressed by drug-induced phospholipidosis.
    Experimental lung research, 1982, Volume: 4, Issue:1

    Topics: Aerosols; Animals; Chlorphentermine; Foam Cells; Lipidoses; Macrophages; Male; Particle Size; Phagocytosis; Phospholipids; Pulmonary Alveoli; Rats; Time Factors; Titanium; Zinc Oxide

1982
Impairment of renal function in rats with generalized lipidosis as induced by chlorphentermine.
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:5

    Topics: Animals; Blood Urea Nitrogen; Chlorphentermine; Creatinine; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Kidney; Kidney Concentrating Ability; Lipidoses; Male; Microscopy, Electron; Phentermine; Rats; Water Deprivation

1981
Chlorphentermine-induced phospholipidosis in rat alveolar macrophages--luminol-dependent chemiluminescence.
    Biochemical pharmacology, 1981, Jan-15, Volume: 30, Issue:2

    Topics: Animals; Chlorphentermine; Lipidoses; Luminescent Measurements; Luminol; Macrophages; Male; Phentermine; Phospholipids; Pulmonary Alveoli; Rats

1981
Role of drug metabolism in protection against chlorphentermine-induced pulmonary phospholipidosis in adult rat.
    Experimental and molecular pathology, 1981, Volume: 35, Issue:1

    Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Body Weight; Chlorphentermine; Cytochrome P-450 CYP1A1; Lipidoses; Liver; Lung; Lung Diseases; Male; Microsomes, Liver; Organ Size; Oxazines; Oxidoreductases; Phenobarbital; Phentermine; Phospholipids; Rats

1981
Studies on the mechanism of drug-induced lipidosis. Cationic amphiphilic drug inhibition of lysosomal phospholipases A and C.
    Biochemical pharmacology, 1981, May-15, Volume: 30, Issue:10

    Topics: Amantadine; Aniline Compounds; Animals; Chlorphentermine; Chlorpromazine; Heptanes; Imipramine; Lipidoses; Liver; Lysosomes; Male; Pharmacology; Phospholipases; Phospholipases A; Propranolol; Rats; Tripelennamine; Type C Phospholipases

1981
Recovery from chlorphentermine-induced phospholipidosis in rat alveolar macrophages: morphological features.
    Experimental and molecular pathology, 1981, Volume: 35, Issue:3

    Topics: Animals; Chlorphentermine; Intracellular Membranes; Lipidoses; Macrophages; Male; Microscopy, Electron; Phentermine; Phospholipids; Pulmonary Alveoli; Rats

1981
Enhanced phagocytic and bactericidal activities of phospholipidotic rat alveolar macrophages.
    Journal of the Reticuloendothelial Society, 1981, Volume: 30, Issue:6

    Topics: Animals; Blood Bactericidal Activity; Chlorphentermine; Iprindole; Lipidoses; Lysosomes; Macrophages; Opsonin Proteins; Phagocytosis; Pulmonary Alveoli; Rats; Receptors, Fc; Rosette Formation

1981
Chemiluminescence from rat alveolar macrophages following induction of phospholipidosis with chlorphentermine.
    Toxicology and applied pharmacology, 1980, Mar-15, Volume: 52, Issue:3

    Topics: Animals; Catalase; Cell Count; Chlorphentermine; Hydrogen Peroxide; Immunity; In Vitro Techniques; Lipid Peroxides; Lipidoses; Luminescent Measurements; Macrophages; Male; Oxygen Consumption; Phentermine; Phospholipids; Pulmonary Alveoli; Rats; Superoxide Dismutase

1980
Effects of several lipidosis-including drugs upon the area postrema and adjacent medullary nuclei of adult rats. I. Alterations is perikarya and dendrites.
    Acta neuropathologica, 1980, Volume: 52, Issue:3

    Topics: Animals; Blood-Brain Barrier; Brain Diseases; Chloroquine; Chlorphentermine; Female; Lipidoses; Male; Medulla Oblongata; Microscopy, Electron; Perhexiline; Piperidines; Quinacrine; Rats; Time Factors

1980
Experimental lipidosis of the inner ear.
    Archives of oto-rhino-laryngology, 1980, Volume: 229, Issue:3-4

    Topics: Animals; Auditory Pathways; Chloroquine; Chlorphentermine; Guinea Pigs; Hair Cells, Auditory, Inner; Iprindole; Lipidoses; Nerve Fibers; Organ of Corti

1980
In vivo and in vitro reversibility of chlorphentermine-induced phospholipidosis in rat alveolar macrophages.
    Experimental and molecular pathology, 1995, Volume: 62, Issue:1

    Topics: Animals; Cells, Cultured; Chlorphentermine; Lipidoses; Lysosomes; Macrophages, Alveolar; Male; Phospholipids; Rats; Rats, Sprague-Dawley

1995
Chlorphentermine-induced lipidosis in the rat retina: a functional and morphological study.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1994, Volume: 232, Issue:6

    Topics: Administration, Oral; Animals; Chlorphentermine; Electroretinography; Female; Lipidoses; Rats; Rats, Wistar; Retinal Diseases

1994
Experimental chlorphentermine lipidosis of the retina in albino rats.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1993, Volume: 206, Issue:2

    Topics: Animals; Chlorphentermine; Disease Models, Animal; Female; Inclusion Bodies; Lipidoses; Lysosomes; Optic Nerve; Pigment Epithelium of Eye; Rats; Retina; Retinal Diseases; Time Factors

1993
Experimentally induced lipidosis in uterine and vaginal epithelium of rats.
    Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft, 1994, Volume: 176, Issue:1

    Topics: Animals; Chlorphentermine; Dose-Response Relationship, Drug; Epithelium; Estrus; Female; Imipramine; Lipidoses; Lysosomes; Microscopy, Electron; Rats; Rats, Wistar; Uterus; Vagina

1994
X-ray microanalysis of cultured alveolar macrophages with phospholipidosis.
    Experimental and molecular pathology, 1993, Volume: 58, Issue:2

    Topics: Amiodarone; Animals; Cell Nucleus; Cells, Cultured; Chlorphentermine; Electron Probe Microanalysis; Freeze Drying; Frozen Sections; Inclusion Bodies; Lipidoses; Macrophages, Alveolar; Male; Phospholipids; Potassium; Rats; Rats, Inbred F344; Sodium

1993
[Chloroquine- and chlorphentermin-induced lipidosis in rat retina].
    Klinische Monatsblatter fur Augenheilkunde, 1999, Volume: 214, Issue:3

    Topics: Administration, Oral; Animals; Chloroquine; Chlorphentermine; Dose-Response Relationship, Drug; Electroretinography; Female; Lipidoses; Rats; Rats, Wistar; Retina; Retinal Cone Photoreceptor Cells; Time Factors

1999
[Chloroquine keratopathy as an example of drug-induced phospholipidosis (contribution to the pathogenesis of cornea verticillata) (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1977, Volume: 170, Issue:1

    Topics: Adrenal Glands; Animals; Chloroquine; Chlorphentermine; Corneal Diseases; Cytoplasm; Hydrogen-Ion Concentration; Kidney; Lipidoses; Lung; Lysosomes; Myocardium; Phospholipases; Phospholipids; Rats; Structure-Activity Relationship

1977
Increased lysosomal enzyme activities in tissues of rats suffering from chlorphentermine induced lipidosis.
    Biochemical pharmacology, 1979, Apr-01, Volume: 28, Issue:7

    Topics: Acid Phosphatase; Adrenal Glands; Animals; beta-Galactosidase; Chlorphentermine; Glucuronidase; Kidney Cortex; Lipidoses; Liver; Lysosomes; Male; Mannosidases; Phentermine; Rats

1979
Chlorphentermine-induced lipidosislike ultrastructural alterations in testicular Leydig and Sertoli cells.
    Experimental and molecular pathology, 1975, Volume: 22, Issue:1

    Topics: Animals; Chlorphentermine; Crystallography; Disease Models, Animal; Inclusion Bodies; Leydig Cells; Lipidoses; Lipids; Lysosomes; Male; Mice; Microscopy, Electron; Phentermine; Rabbits; Rats; Sertoli Cells; Testicular Diseases; Testis

1975
Lipidosislike renal changes in rats treated with chlorphentermine or with tricyclic antidepressants.
    Virchows Archiv. B, Cell pathology, 1975, Volume: 18, Issue:1

    Topics: Animals; Antidepressive Agents, Tricyclic; Chlorphentermine; Female; Imipramine; Inclusion Bodies; Iprindole; Kidney; Kidney Diseases; Kidney Glomerulus; Kidney Tubules, Proximal; Lipidoses; Male; Microscopy, Electron; Phentermine; Rats

1975
Alterations in the neurohypophysis of rats treated with chlorphentermine or tricyclic antidepressants.
    Cell and tissue research, 1976, Jul-06, Volume: 169, Issue:4

    Topics: Animals; Antidepressive Agents, Tricyclic; Chlorphentermine; Female; Inclusion Bodies; Lipidoses; Male; Phentermine; Pituitary Gland, Posterior; Rats

1976
Axonal and cellular alterations in the inner ear of rats treated with chlorphentermine or iprindole.
    Virchows Archiv. B, Cell pathology, 1977, Jan-20, Volume: 23, Issue:1

    Topics: Animals; Axons; Chlorphentermine; Ear, Inner; Female; Inclusion Bodies; Indoles; Iprindole; Lipidoses; Male; Microscopy, Electron; Phentermine; Rats

1977
Anterior polar cataract and lysosomal alterations in the lens of rats treated with the amphiphilic lipidosis-inducing drugs chloroquine and chlorphentermine.
    Virchows Archiv. B, Cell pathology, 1978, May-19, Volume: 27, Issue:3

    Topics: Acid Phosphatase; Animals; Cataract; Chloroquine; Chlorphentermine; Epithelium; Female; Inclusion Bodies; Lens, Crystalline; Lipidoses; Lysosomes; Male; Phagocytosis; Phentermine; Rats

1978
[Ultrastructural changes of nerve endings and sensory cells of the rat inner ear following treatment with amphiphilic drugs].
    Verhandlungen der Anatomischen Gesellschaft, 1978, Issue:72

    Topics: Animals; Chlorphentermine; Ear, Inner; Inclusion Bodies; Indoles; Iprindole; Lipidoses; Nerve Endings; Phentermine; Rats; Sensory Receptor Cells

1978
Freeze-fracture studies of cytoplasmic inclusions occurring in experimental lipidosis as induced by amphiphilic cationic drugs.
    Biochimica et biophysica acta, 1979, Oct-26, Volume: 575, Issue:1

    Topics: Adrenal Glands; Animals; Chlorphentermine; Freeze Fracturing; Inclusion Bodies; Lipidoses; Phentermine; Phospholipids; Pigment Epithelium of Eye; Rats; Retina

1979
Biochemical characteristics of rat alveolar macrophages with chlorphentermine-induced phospholipidosis: variations with increasing cell size.
    Experimental and molecular pathology, 1979, Volume: 31, Issue:2

    Topics: Animals; Cell Separation; Chlorphentermine; Hydrolases; L-Lactate Dehydrogenase; Lipidoses; Macrophages; Male; Phospholipids; Proteins; Rats

1979
[Drug-induced phospholipidosis. An example of the use of NMR spectroscopy in pharmacologic research].
    Pharmazie in unserer Zeit, 1978, Volume: 7, Issue:4

    Topics: Animals; Antidepressive Agents; Chlorphentermine; Guinea Pigs; Lipidoses; Magnetic Resonance Spectroscopy; Phentermine; Phospholipids; Structure-Activity Relationship

1978
Myopathy in rats treated with chlorphentermine or iprindole.
    Virchows Archiv. B, Cell pathology, 1976, May-26, Volume: 20, Issue:4

    Topics: Animals; Chlorphentermine; Female; Indoles; Iprindole; Lipidoses; Male; Muscles; Muscular Diseases; Phentermine; Rats

1976
Lens opacities associated with lipidosis-like ultrastructural alterations in rats treated with chloroquine, chlorphentermine, or iprindole.
    Experimental eye research, 1977, Volume: 24, Issue:6

    Topics: Animals; Cataract; Chloroquine; Chlorphentermine; Cytoplasm; Epithelial Cells; Epithelium; Female; Indoles; Iprindole; Lens, Crystalline; Lipid Metabolism; Lipidoses; Male; Phentermine; Rats

1977
Lysosomal alterations in cultured macrophages exposed to anorexigenic and psychotropic drugs.
    Laboratory investigation; a journal of technical methods and pathology, 1976, Volume: 35, Issue:2

    Topics: Acid Phosphatase; Animals; Antidepressive Agents, Tricyclic; Appetite Depressants; Chlorphentermine; Chlorpromazine; Lipid Metabolism; Lipidoses; Lysosomes; Macrophages; Microscopy, Electron; Phentermine; Rats; Structure-Activity Relationship

1976
Palmitic acid-1-14C incorporation and turnover in lung phospholipids of rats treated with chlorphentermine, RMI 10.393 and Ro 4-4318.
    Archives of toxicology, 1976, Jun-08, Volume: 35, Issue:3

    Topics: Amitriptyline; Animals; Chlorphentermine; Female; Fluorenes; Lipidoses; Lung; Palmitic Acids; Phentermine; Phospholipids; Piperidines; Rats

1976
Effect of chlorphentermine on the lipids of rat lungs.
    Thorax, 1976, Volume: 31, Issue:5

    Topics: Animals; Body Weight; Chlorphentermine; Chromatography, Gas; Chromatography, Liquid; Chromatography, Thin Layer; Fatty Acids; Lipid Metabolism; Lipidoses; Lung; Male; Organ Size; Phentermine; Phosphatidylcholines; Phospholipids; Rats

1976
Drug-induced foam cell reactions in rats, II. Chemical analysis of lipids stored in lungs and foam cells after treatment with chlorphentermine, 5-[p-(fluoren-9-ylidenemethyl)phenyl]-2-piperidineethanol (RMI 10.393) and 1-chloramitriptyline.
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1975, Volume: 356, Issue:7

    Topics: Amitriptyline; Animals; Chlorphentermine; Cholesterol; Cholesterol Esters; Fatty Acids, Nonesterified; Female; Fluorenes; Lipidoses; Lipids; Lung; Phentermine; Phospholipids; Piperidines; Rats; Triglycerides

1975
Influence of a pre-existing phospholipidosis on the accumulation of amiodarone and desethylamiodarone in rat alveolar macrophages.
    Research communications in chemical pathology and pharmacology, 1991, Volume: 72, Issue:2

    Topics: Amiodarone; Animals; Chlorphentermine; Lipidoses; Macrophages; Male; Phospholipids; Pulmonary Alveoli; Rats; Rats, Inbred F344

1991
Newborn response to cationic amphiphilic drugs.
    Federation proceedings, 1985, Volume: 44, Issue:7

    Topics: Animals; Animals, Newborn; Chlorphentermine; Dexamethasone; Drug Interactions; Female; Fetus; Gentamicins; Lipidoses; Lung; Phenobarbital; Phentermine; Phospholipids; Piperazines; Pregnancy; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride; Triparanol

1985
Role of phospholipase C in chlorphentermine-induced pulmonary phospholipidosis in rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1988, Volume: 188, Issue:1

    Topics: Alkaline Phosphatase; Animals; Chlorphentermine; Lipidoses; Lung; Lung Diseases; Male; Phentermine; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Type C Phospholipases

1988
Cytochemical demonstration of increased phospholipid content in cell membranes in chlorphentermine-induced phospholipidosis.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1989, Volume: 37, Issue:2

    Topics: Animals; Cell Membrane; Chlorphentermine; Gold; Histocytochemistry; Kidney; Lipidoses; Lung; Male; Membrane Lipids; Microscopy, Electron; Phentermine; Phospholipids; Rats

1989
Amantadine-induced lipidosis. A cytological and physicochemical study.
    Toxicology, 1987, Volume: 44, Issue:1

    Topics: Amantadine; Animals; Cells, Cultured; Chlorphentermine; Inclusion Bodies; Kidney; Lipidoses; Liver; Lymphocytes; Nervous System; Phospholipids; Rats; Rats, Inbred Strains; Temperature

1987
Cationic amphiphilic drug-induced renal cortical lysosomal phospholipidosis: an in vivo comparative study with gentamicin and chlorphentermine.
    Toxicology and applied pharmacology, 1987, Volume: 91, Issue:3

    Topics: Animals; Chlorphentermine; Gentamicins; Kidney Cortex; Lipidoses; Lysosomes; Male; Phentermine; Phospholipids; Rats; Rats, Inbred Strains; Type C Phospholipases

1987
Fusion of storage lysosomes in experimental lipidosis and glycogenosis.
    Experimental and molecular pathology, 1987, Volume: 46, Issue:1

    Topics: Acarbose; Animals; Autophagy; Chloroquine; Chlorphentermine; Endocytosis; Female; Glycogen Storage Disease; Kidney Tubules; Kidney Tubules, Collecting; Lipidoses; Liver; Lysosomes; Membrane Fusion; Rats; Rats, Inbred Strains; Trisaccharides; Vacuoles

1987
The effect of chlorphentermine pretreatment on the toxicity of nitrogen dioxide in mice.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1987, Volume: 9, Issue:1

    Topics: Animals; Body Weight; Cell Count; Chlorphentermine; Hyperplasia; Lipidoses; Lung; Macrophages; Male; Mice; Microscopy, Electron; Nitrogen Dioxide; Phentermine

1987
Role of the alveolar macrophage in the induction of pulmonary phospholipidosis by chlorphentermine. I. Drug and phospholipid levels.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:1

    Topics: Animals; Chlorphentermine; Lipidoses; Lung Diseases; Macrophages; Male; Phentermine; Phospholipids; Pulmonary Alveoli; Rats

1986
Role of the alveolar macrophage in the induction of pulmonary phospholipidosis by chlorphentermine. II. Drug uptake into cells in vitro.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:1

    Topics: Animals; Biological Transport; Chlorphentermine; In Vitro Techniques; Kinetics; Lipidoses; Lung Diseases; Macrophages; Male; Phentermine; Phospholipids; Pulmonary Alveoli; Rats; Sodium

1986
Gentamicin or chlorphentermine induction of phospholipidosis in the developing organism: role of tissue and species in manifestation of toxicity.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:1

    Topics: Animals; Animals, Newborn; Chlorphentermine; Female; Gentamicins; Kidney; Lipidoses; Liver; Lung; Phentermine; Phospholipids; Rats; Rats, Inbred Strains

1985
Chlorphentermine-induced lipidosislike ultrastructural alterations in lungs and adrenal glands of several species.
    Toxicology and applied pharmacology, 1974, Volume: 30, Issue:3

    Topics: Adrenal Cortex; Adrenal Glands; Anesthesia; Animals; Chlorphentermine; Cytoplasmic Granules; Guinea Pigs; Lipidoses; Lung; Male; Mice; Mice, Inbred Strains; Microscopy, Electron; Phentermine; Rabbits; Species Specificity; Staining and Labeling; Time Factors

1974
Drug-induced phospholipidosis. I. Lipid composition and chlorphentermine content of rat lung tissue and alveolar macrophages after chronic treatment.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 283, Issue:3

    Topics: Animals; Appetite Depressants; Binding Sites; Chlorphentermine; Cholesterol; Injections, Intraperitoneal; Lipid Metabolism; Lipidoses; Lung; Macrophages; Male; Organ Size; Phenethylamines; Phospholipids; Plasmalogens; Pulmonary Alveoli; Rats; Triglycerides

1974
The ultrastructure of rat lung changes induced by an anorectic drug (chlorphentermine).
    Virchows Archiv. B, Cell pathology, 1972, Volume: 11, Issue:2

    Topics: Acid Phosphatase; Animals; Appetite Depressants; Chlorphentermine; Inclusion Bodies; Lipidoses; Lung; Lung Diseases; Macrophages; Male; Microscopy, Electron; Phenethylamines; Phospholipids; Pulmonary Alveoli; Rats

1972
Chlorphentermine-induced ultrastructural alterations in foetal tissues.
    Virchows Archiv. B, Cell pathology, 1973, Mar-30, Volume: 12, Issue:4

    Topics: Animals; Appetite Depressants; Cell Nucleus; Chlorphentermine; Cilia; Crystallization; Endothelium; Epithelial Cells; Female; Fetal Diseases; Fetal Heart; Fetus; Inclusion Bodies; Lipidoses; Lung; Macrophages; Phenethylamines; Phospholipids; Pregnancy; Rats

1973
A comparative ultrastructural study of the effects of chlorphentermine and triparanol in rat lung and adrenal gland.
    Virchows Archiv. B, Cell pathology, 1973, Jan-31, Volume: 12, Issue:2

    Topics: Adrenal Gland Diseases; Adrenal Glands; Adrenal Medulla; Animals; Appetite Depressants; Chlorphentermine; Cytoplasm; Inclusion Bodies; Lipidoses; Lung; Lung Diseases; Macrophages; Male; Microscopy, Electron; Phenethylamines; Rats; Triparanol

1973
Chlorphentermine-induced ultrastructural changes in liver tissues of four animal species.
    Virchows Archiv. B, Cell pathology, 1973, Aug-21, Volume: 13, Issue:4

    Topics: Animals; Appetite Depressants; Chlorphentermine; Guinea Pigs; Inclusion Bodies; Kupffer Cells; Lipidoses; Liver; Lysosomes; Male; Mice; Phenethylamines; Phospholipids; Rabbits; Rats

1973
[Lipidosis of the nervous system following chlorphentermine administration].
    Die Naturwissenschaften, 1974, Volume: 61, Issue:1

    Topics: Animals; Chlorphentermine; Female; Inclusion Bodies; Injections, Intraperitoneal; Lipidoses; Mice; Nerve Tissue; Pregnancy

1974
Lipidosis-like cellular alterations in lymphatic tissues of chlorphentermine-treated animals.
    Virchows Archiv. B, Cell pathology, 1974, Volume: 15, Issue:4

    Topics: Animals; Appetite Depressants; Cell Membrane; Chlorphentermine; Female; Guinea Pigs; Hindlimb; Inclusion Bodies; Lipidoses; Lymph Nodes; Lymphocytes; Lysosomes; Male; Mice; Peyer's Patches; Phenethylamines; Phospholipids; Plasma Cells; Rabbits; Rats; Reticulocytes; Spleen; Thymus Gland

1974
Retinal lesions in rat after treatment with chlorphentermine or with tricyclic antidepressants.
    Virchows Archiv. B, Cell pathology, 1974, Volume: 15, Issue:4

    Topics: Amitriptyline; Animals; Antidepressive Agents; Appetite Depressants; Chlorphentermine; Cytoplasm; Dibenzazepines; Epithelial Cells; Epithelium; Female; Ganglia; Histocytochemistry; Imipramine; Inclusion Bodies; Iprindole; Lipidoses; Lysosomes; Male; Microscopy, Electron; Phenethylamines; Propylamines; Rats; Retinal Diseases; Retinal Pigments

1974
Lipidosis-like alterations in hypothalamic neurosecretory cells of rats treated with chlorphentermine or iprindole.
    Cell and tissue research, 1974, Jun-24, Volume: 149, Issue:4

    Topics: Animals; Antidepressive Agents; Appetite Depressants; Chlorphentermine; Crystallization; Hypothalamus; Inclusion Bodies; Indoles; Iprindole; Lipidoses; Male; Microscopy, Electron; Neurosecretion; Phenethylamines; Rats

1974
Lipidosis-like alterations in spinal cord and cerebellar cortex of rats treated with chlorphentermine or tricylic antidepressants.
    Acta neuropathologica, 1974, Volume: 29, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents; Cerebellar Cortex; Chlorphentermine; Cytoplasmic Granules; Iprindole; Lipidoses; Lysosomes; Male; Neurons; Phentermine; Rats; Spinal Cord

1974