chlorpheniramine has been researched along with Stevens-Johnson Syndrome in 3 studies
Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.
Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We selected adverse drug reaction (ADR) reports on H1-antihistamines in children (0-16 years) up to June 2014 from VigiBase." | 1.46 | Safety profile of H1-antihistamines in pediatrics: an analysis based on data from VigiBase. ( Biagi, C; Calamelli, E; Cipriani, F; Donati, M; Melis, M; Monaco, L; Motola, D; Ricci, G; Vaccheri, A, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Motola, D | 1 |
| Donati, M | 1 |
| Biagi, C | 1 |
| Calamelli, E | 1 |
| Cipriani, F | 1 |
| Melis, M | 1 |
| Monaco, L | 1 |
| Vaccheri, A | 1 |
| Ricci, G | 1 |
| Sahagún Flores, JE | 1 |
| Soto Ortiz, JA | 1 |
| Tovar Méndez, CE | 1 |
| Cárdenas Ochoa, EC | 1 |
| Hernández Flores, G | 1 |
| Hunter, JA | 1 |
| Davison, AM | 1 |
3 other studies available for chlorpheniramine and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
Safety profile of H1-antihistamines in pediatrics: an analysis based on data from VigiBase.
Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Cetirizine; Child; Child Mortality; Child, Pres | 2017 |
[Stevens-Johnson syndrome plus intrahepatic cholestasis caused by clindamycin or chlorpheniramine].
Topics: Acetaminophen; Betamethasone; Bronchitis; Chlorpheniramine; Cholestasis, Intrahepatic; Clindamycin; | 2009 |
Toxic epidermal necrolysis associated with pentazocine therapy and severe reversible renal failure.
Topics: Acetaminophen; Acute Kidney Injury; Blood Cells; Blood Pressure; Chlorpheniramine; Cloxacillin; Dext | 1973 |