chlorpheniramine has been researched along with Sneezing in 9 studies
Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.
Sneezing: The sudden, forceful, involuntary expulsion of air from the NOSE and MOUTH caused by irritation to the MUCOUS MEMBRANES of the upper RESPIRATORY TRACT.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This paper presents the results of a randomized, double-blind, placebo-controlled study of the efficacy of chlorpheniramine in relieving the symptoms and attenuating the pathophysiologic correlates of a rhinovirus "common cold." | 5.06 | A double-blind, placebo-controlled clinical trial of the effect of chlorpheniramine on the response of the nasal airway, middle ear and eustachian tube to provocative rhinovirus challenge. ( Doyle, WJ; Gwaltney, JM; Maddern, BR; McBride, TP; Skoner, DP; Uhrin, M, 1988) |
| "The histamine-induced increase in nasal airway resistance was 52% inhibited by combined use of the two antihistamine sprays (p less than 0." | 2.65 | Significance of H1 and H2 receptors in the human nose: rationale for topical use of combined antihistamine preparations. ( Borum, P; Kirkegaard, J; Maansson, A; Mygind, N; Osterhammel, P; Secher, C, 1982) |
| "BW A868C was more potent in inhibiting the nasal symptoms than ramatroban." | 1.34 | Interactive effect of histamine and prostaglandin D2 on nasal allergic symptoms in rats. ( Ago, J; Inoue, T; Ishikawa, T; Kamei, C; Rahman, A, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mizuguchi, H | 1 |
| Hatano, M | 1 |
| Matsushita, C | 1 |
| Umehara, H | 1 |
| Kuroda, W | 1 |
| Kitamura, Y | 1 |
| Takeda, N | 1 |
| Fukui, H | 1 |
| Gwaltney, JM | 2 |
| Winther, B | 1 |
| Patrie, JT | 1 |
| Hendley, JO | 1 |
| Rahman, A | 1 |
| Inoue, T | 2 |
| Ago, J | 1 |
| Ishikawa, T | 2 |
| Kamei, C | 3 |
| Rahman, MA | 1 |
| Yatsuzuka, R | 1 |
| Ohtsu, H | 1 |
| Munch, EP | 1 |
| Søborg, M | 1 |
| Nørreslet, TT | 1 |
| Mygind, N | 2 |
| Secher, C | 1 |
| Kirkegaard, J | 1 |
| Borum, P | 1 |
| Maansson, A | 1 |
| Osterhammel, P | 1 |
| D'Agostino, RB | 2 |
| Weintraub, M | 1 |
| Russell, HK | 1 |
| Stepanians, M | 1 |
| Cantilena, LR | 1 |
| Graumlich, JF | 1 |
| Maldonado, S | 1 |
| Honig, P | 1 |
| Anello, C | 1 |
| Sugimoto, Y | 1 |
| Kawamoto, E | 1 |
| Chen, Z | 1 |
| Doyle, WJ | 1 |
| McBride, TP | 1 |
| Skoner, DP | 1 |
| Maddern, BR | 1 |
| Uhrin, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase III Study Comparing Coristina® D to Resfenol® in the Symptomatic Treatment of Common Cold[NCT02735070] | Phase 3 | 366 participants (Anticipated) | Interventional | 2016-09-30 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for chlorpheniramine and Sneezing
| Article | Year |
|---|---|
The effectiveness of antihistamines in reducing the severity of runny nose and sneezing: a meta-analysis.
Topics: Chlorpheniramine; Clinical Trials as Topic; Doxylamine; Histamine H1 Antagonists; Humans; Nasal Obst | 1998 |
4 trials available for chlorpheniramine and Sneezing
| Article | Year |
|---|---|
Combined antiviral-antimediator treatment for the common cold.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Chlorpheniramine; Common Cold; Cough; Do | 2002 |
A comparative study of dexchlorpheniramine maleate sustained release tablets and budesonide nasal spray in seasonal allergic rhinitis.
Topics: Administration, Intranasal; Adolescent; Adult; Aerosols; Anti-Inflammatory Agents; Budesonide; Chlor | 1983 |
Significance of H1 and H2 receptors in the human nose: rationale for topical use of combined antihistamine preparations.
Topics: Administration, Topical; Adult; Airway Resistance; Chlorpheniramine; Drug Therapy, Combination; Fema | 1982 |
A double-blind, placebo-controlled clinical trial of the effect of chlorpheniramine on the response of the nasal airway, middle ear and eustachian tube to provocative rhinovirus challenge.
Topics: Acoustic Impedance Tests; Adult; Chlorpheniramine; Clinical Trials as Topic; Common Cold; Double-Bli | 1988 |
4 other studies available for chlorpheniramine and Sneezing
| Article | Year |
|---|---|
Repeated pre-treatment with antihistamines suppresses [corrected] transcriptional up-regulations of histamine H(1) receptor and interleukin-4 genes in toluene-2,4-diisocyanate-sensitized rats.
Topics: Animals; Chlorpheniramine; Dibenzazepines; Dibenzoxepins; Drug Administration Schedule; Histamine H1 | 2008 |
Interactive effect of histamine and prostaglandin D2 on nasal allergic symptoms in rats.
Topics: Administration, Intranasal; Administration, Oral; Animals; Carbazoles; Chlorpheniramine; Cyproheptad | 2007 |
Involvement of chemical mediators in nasal allergic responses of HDC-KO mice.
Topics: Animals; Behavior, Animal; Chlorpheniramine; Histamine H1 Antagonists; Histidine Decarboxylase; Hyda | 2007 |
A new model of allergic rhinitis in rats by topical sensitization and evaluation of H(1)-receptor antagonists.
Topics: Allergens; Animals; Anti-Allergic Agents; Astemizole; Chlorpheniramine; Dibenzazepines; Disease Mode | 2000 |