chlorpheniramine has been researched along with Serotonin Syndrome in 4 studies
Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.
Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An 18-year-old male developed a severe serotonin syndrome after recreational ingestion of Coricidin HBP (chlorpheniramine 4 mg and dextromethorphan hydrobromide 30 mg)." | 7.74 | Serotonin syndrome in dextromethorphan ingestion responsive to propofol therapy. ( Babu, KM; Boyer, EW; Ganetsky, M, 2007) |
| "An 18-year-old male developed a severe serotonin syndrome after recreational ingestion of Coricidin HBP (chlorpheniramine 4 mg and dextromethorphan hydrobromide 30 mg)." | 3.74 | Serotonin syndrome in dextromethorphan ingestion responsive to propofol therapy. ( Babu, KM; Boyer, EW; Ganetsky, M, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Karamanakos, PN | 2 |
| Panteli, ES | 1 |
| Alisky, JM | 1 |
| Ganetsky, M | 1 |
| Babu, KM | 1 |
| Boyer, EW | 1 |
4 other studies available for chlorpheniramine and Serotonin Syndrome
| Article | Year |
|---|---|
Comment on "Dextromethorphan-induced serotonin syndrome".
Topics: Chlorpheniramine; Dextromethorphan; Drug Interactions; Histamine H1 Antagonists; Humans; Selective S | 2008 |
Can chlorpheniramine cause serotonin syndrome?
Topics: Chlorpheniramine; Histamine H1 Antagonists; Humans; Serotonin Syndrome | 2006 |
Can chlorpheniramine cause serotonin syndrome?
Topics: Chlorpheniramine; Histamine H1 Antagonists; Humans; Selective Serotonin Reuptake Inhibitors; Seroton | 2007 |
Serotonin syndrome in dextromethorphan ingestion responsive to propofol therapy.
Topics: Acetaminophen; Adolescent; Algorithms; Chlorpheniramine; Dextromethorphan; Drug Combinations; Drug O | 2007 |