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chlorpheniramine and Rhinitis, Allergic, Perennial

chlorpheniramine has been researched along with Rhinitis, Allergic, Perennial in 29 studies

Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.

Rhinitis, Allergic, Perennial: Inflammation of the mucous membrane of the nose similar to that found in hay fever except that symptoms persist throughout the year. The causes are usually air-borne allergens, particularly dusts, feathers, molds, animal fur, etc.

Research Excerpts

ExcerptRelevanceReference
"We describe the first reported case of painless thyroiditis induced by an abrupt cessation of betamethasone."8.81Painless thyroiditis induced by the cessation of betamethasone. ( Morita, S; Ueda, Y; Yokoyama, N, 2001)
"We describe the first reported case of painless thyroiditis induced by an abrupt cessation of betamethasone."4.81Painless thyroiditis induced by the cessation of betamethasone. ( Morita, S; Ueda, Y; Yokoyama, N, 2001)
"Terfenadine did not increase the latency of P300-event-related potentials at the parietal (Pz) or frontal (Fz) scalp electrodes compared with baseline, in contrast to chlorpheniramine and placebo, which did increase P300 latency."2.67Benefit/risk ratio of the antihistamines (H1-receptor antagonists) terfenadine and chlorpheniramine in children. ( Reggin, JD; Roberts, JR; Simons, FE; Simons, KJ, 1994)
"Loratadine was administered in a single daily dose of 5 mg (2."2.67[Loratadine and dexchlorpheniramine in the treatment of perennial allergic rhinitis in pediatric patients]. ( Longo, G; Marchesi, E; Poli, F; Ventura, A, 1990)
" This was a 4-week study with a 1-week observation (baseline) period and a 3-week period during which the response to three dosage regimens (2 mg per day, 4 mg per day, and 8 mg per day) of FCB and placebo were compared to baseline observations of rhinitis."2.66Efficacy and tolerance of fluocortin butyl administered twice daily in adult patients with perennial rhinitis. ( Hartley, TF; Lieberman, PL; Meltzer, EO; Noyes, JN; Pearlman, DS; Tinkelman, DG, 1985)
" Three separate dosage regimens were employed."2.65Multi-center, double-blind, placebo-controlled trial of fluocortin butyl in perennial rhinitis. ( Arbesman, C; Bernstein, IL; Bierman, CW; Bocles, JS; Katz, R; Lieberman, PL; Mattucci, K; Meltzer, EO; Middleton, E; Noyes, J; Pearlman, DS; Pence, HL; Slavin, RG; Spector, SL, 1983)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199011 (37.93)18.7374
1990's10 (34.48)18.2507
2000's8 (27.59)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Izumi, N1
Mizuguchi, H1
Umehara, H1
Ogino, S1
Fukui, H3
Ng, KH1
Chong, D1
Wong, CK1
Ong, HT1
Lee, CY1
Lee, BW1
Shek, LP1
Murata, Y2
Miyoshi, A2
Kitamura, Y2
Takeda, N2
Maeyama, K1
Brostoff, J1
Lockhart, JD1
Aguilar Angeles, D1
Navarro, BE1
Velázquez Sámano, G1
Brewster, BS1
Arbesman, C1
Bernstein, IL1
Bierman, CW1
Bocles, JS1
Katz, R1
Lieberman, PL2
Mattucci, K1
Meltzer, EO2
Middleton, E1
Noyes, J1
Pearlman, DS2
Pence, HL1
Slavin, RG1
Spector, SL1
Kirkegaard, J1
Secher, C1
Borum, P1
Mygind, N1
Wheatley, D1
Wong, L1
Hendeles, L1
Weinberger, M1
Heyneman, CA1
Nishikawa, M1
Hikosaka, M1
Yonemoto, T1
Gondou, A1
Tabata, S1
Ogawa, Y1
Kanasaki, M1
Miyake, Y1
Shimizu, H1
Shouzu, A1
Simons, FE1
Reggin, JD1
Roberts, JR1
Simons, KJ1
Kelso, JM1
Crawford, WW1
Klaustermeyer, WB1
Lee, PH1
Placik, IM1
Bao, L1
Sun, QW1
Hu, L1
Shimizu, T1
Hirano, H1
Majima, Y1
Sakakura, Y1
Sugimoto, Y1
Kawamoto, E1
Chen, Z1
Kamei, C1
Morita, S1
Ueda, Y1
Yokoyama, N1
Nwawolo, CC1
Olusesi, AD1
Bachmann, W1
Wood, SF1
Takahashi, N1
Aramaki, Y1
Tsuchiya, S1
Longo, G1
Poli, F1
Ventura, A1
Marchesi, E1
Pukander, JS1
Karma, PH1
Penttilä, MA1
Perälä, ME1
Ylitalo, P1
Kataja, MJ1
von Maur, K1
Sooknundun, M1
Kacker, SK1
Sundaram, KR1
Hartley, TF1
Noyes, JN1
Tinkelman, DG1

Reviews

3 reviews available for chlorpheniramine and Rhinitis, Allergic, Perennial

ArticleYear
Histamine2-antagonists in allergic disorders.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:6

    Topics: Asthma; Chlorpheniramine; Cimetidine; Clemastine; Clinical Trials as Topic; Drug Therapy, Combinatio

1994
Painless thyroiditis induced by the cessation of betamethasone.
    Internal medicine (Tokyo, Japan), 2001, Volume: 40, Issue:8

    Topics: Anti-Allergic Agents; Anti-Inflammatory Agents; Betamethasone; Chlorpheniramine; Drug Combinations;

2001
Clinical experience with non-sedating antihistamines in paediatric allergic rhinitis.
    Rhinology. Supplement, 1992, Volume: 13

    Topics: Adolescent; Astemizole; Asthma; Child; Child, Preschool; Chlorpheniramine; Clinical Trials as Topic;

1992

Trials

16 trials available for chlorpheniramine and Rhinitis, Allergic, Perennial

ArticleYear
Central nervous system side effects of first- and second-generation antihistamines in school children with perennial allergic rhinitis: a randomized, double-blind, placebo-controlled comparative study.
    Pediatrics, 2004, Volume: 113, Issue:2

    Topics: Adolescent; Central Nervous System; Cetirizine; Child; Chlorpheniramine; Cross-Over Studies; Double-

2004
Controlled trial of terfenadine and chlorpheniramine maleate in perennial rhinitis.
    Postgraduate medical journal, 1982, Volume: 58, Issue:681

    Topics: Adolescent; Adult; Aged; Benzhydryl Compounds; Chlorpheniramine; Clinical Trials as Topic; Double-Bl

1982
Summary of four UK clinical trials with terfenadine.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:9a

    Topics: Benzhydryl Compounds; Chlorpheniramine; Histamine H1 Antagonists; Humans; Rhinitis, Allergic, Perenn

1982
Multi-center, double-blind, placebo-controlled trial of fluocortin butyl in perennial rhinitis.
    The Journal of allergy and clinical immunology, 1983, Volume: 71, Issue:6

    Topics: Adult; Chlorpheniramine; Clinical Trials as Topic; Double-Blind Method; Ephedrine; Female; Fluocorto

1983
Inhibition of histamine-induced nasal symptoms by the H1 antihistamine chlorpheniramine maleate: demonstration of topical effect.
    British journal of diseases of the chest, 1983, Volume: 77, Issue:2

    Topics: Administration, Intranasal; Adult; Airway Resistance; Chlorpheniramine; Clinical Trials as Topic; Do

1983
Ketotifen in hay fever and allergic rhinitis.
    The Practitioner, 1984, Volume: 228, Issue:1393

    Topics: Adolescent; Adult; Aged; Chlorpheniramine; Clinical Trials as Topic; Double-Blind Method; Female; Hu

1984
Pharmacologic prophylaxis of allergic rhinitis: relative efficacy of hydroxyzine and chlorpheniramine.
    The Journal of allergy and clinical immunology, 1981, Volume: 67, Issue:3

    Topics: Adolescent; Adult; Aged; Chlorpheniramine; Clinical Trials as Topic; Female; Humans; Hydroxyzine; Ma

1981
Benefit/risk ratio of the antihistamines (H1-receptor antagonists) terfenadine and chlorpheniramine in children.
    The Journal of pediatrics, 1994, Volume: 124, Issue:6

    Topics: Action Potentials; Central Nervous System; Child; Chlorpheniramine; Cognition; Double-Blind Method;

1994
Study protocol on azelastine.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1997, Volume: 78, Issue:2

    Topics: Anti-Allergic Agents; Chlorpheniramine; Data Interpretation, Statistical; Double-Blind Method; Drug

1997
Comparative efficacy of terfenadine, loratadine, and astemizole in perennial allergic rhinitis.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1998, Volume: 118, Issue:5

    Topics: Adrenergic Agents; Allergens; Ambulatory Care; Analysis of Variance; Anti-Allergic Agents; Astemizol

1998
[Clinical and experimental study for allergic rhinitis with treatment of biminkang mixture].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1997, Volume: 17, Issue:2

    Topics: Adolescent; Adult; Aged; Animals; Anti-Allergic Agents; Artemisia; Basophil Degranulation Test; Chil

1997
Controlled clinical study of the efficacy of loratadine in Nigerian patients with allergic rhinitis.
    The Nigerian postgraduate medical journal, 2001, Volume: 8, Issue:3

    Topics: Adult; Anti-Allergic Agents; Chlorpheniramine; Female; Histamine H1 Antagonists; Humans; Loratadine;

2001
[Loratadine and dexchlorpheniramine in the treatment of perennial allergic rhinitis in pediatric patients].
    Minerva pediatrica, 1990, Volume: 42, Issue:5

    Topics: Age Factors; Child; Child, Preschool; Chlorpheniramine; Cyproheptadine; Female; Histamine Antagonist

1990
Mequitazine and dexchlorpheniramine in perennial rhinitis. A double-blind cross-over placebo-controlled study.
    Rhinology, 1990, Volume: 28, Issue:4

    Topics: Adolescent; Adult; Chlorpheniramine; Double-Blind Method; Female; Humans; Male; Middle Aged; Phenoth

1990
Antihistamine selection in patients with allergic rhinitis.
    Annals of allergy, 1985, Volume: 55, Issue:3

    Topics: Chlorpheniramine; Clinical Trials as Topic; Diphenhydramine; Histamine H1 Antagonists; Humans; Hydro

1985
Efficacy and tolerance of fluocortin butyl administered twice daily in adult patients with perennial rhinitis.
    The Journal of allergy and clinical immunology, 1985, Volume: 75, Issue:4

    Topics: Adolescent; Adult; Chlorpheniramine; Clinical Trials as Topic; Double-Blind Method; Drug Administrat

1985

Other Studies

10 other studies available for chlorpheniramine and Rhinitis, Allergic, Perennial

ArticleYear
Analysis of disease-dependent sedative profiles of H(1)-antihistamines by large-scale surveillance using the visual analog scale.
    Methods and findings in experimental and clinical pharmacology, 2008, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Butyrophenones; Cetirizine; Child; Chlorpheniram

2008
Up-regulation of histamine H(1) receptors in an allergic rat nasal mucosa model.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2004, Volume: 53 Suppl 1

    Topics: Animals; Chlorpheniramine; Dexamethasone; Histamine; Male; Nasal Mucosa; Rats; Receptors, Histamine

2004
Increase in the level of histidine decarboxylase mRNA expression in nasal mucosa of rats sensitized by toluene diisocyanate.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2004, Volume: 53 Suppl 1

    Topics: Animals; Chlorpheniramine; Dexamethasone; Histamine; Histidine Decarboxylase; Male; Nasal Mucosa; Ra

2004
[Antihistaminics and eosinophils].
    Alergia, 1982, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Chlorpheniramine; Eosinophils; Female; Histamine H1 Antagonists; Humans; Leukocyt

1982
A case of iatrogenic growth retardation induced by a corticosteroid-containing anti-allergic drug.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1995, Volume: 27, Issue:8

    Topics: 17-Hydroxycorticosteroids; Anti-Allergic Agents; Betamethasone; Child; Chlorpheniramine; Glucocortic

1995
A mechanism of antigen-induced mucus production in nasal epithelium of sensitized rats. A comparison with lipopolysaccharide-induced mucus production.
    American journal of respiratory and critical care medicine, 2000, Volume: 161, Issue:5

    Topics: Animals; Antigens; Chlorpheniramine; Chromones; Cimetidine; Dexamethasone; Eosinophils; Histamine H1

2000
A new model of allergic rhinitis in rats by topical sensitization and evaluation of H(1)-receptor antagonists.
    Immunopharmacology, 2000, Volume: 48, Issue:1

    Topics: Allergens; Animals; Anti-Allergic Agents; Astemizole; Chlorpheniramine; Dibenzazepines; Disease Mode

2000
[The antiallergic effect of Balkis. A rhino-manometric study].
    Fortschritte der Medizin, 1979, Dec-13, Volume: 97, Issue:47

    Topics: Chlorpheniramine; Drug Combinations; Drug Evaluation; Etilefrine; Humans; Manometry; Phenylephrine;

1979
Allergic rhinitis model with Brown Norway rat and evaluation of antiallergic drugs.
    Journal of pharmacobio-dynamics, 1990, Volume: 13, Issue:7

    Topics: Acetylglucosaminidase; Administration, Topical; Animals; Anti-Inflammatory Agents; Antigens; Biomark

1990
Treatment of allergic rhinitis with a new long-acting H1 receptor antagonist: astemizole.
    Annals of allergy, 1987, Volume: 58, Issue:1

    Topics: Adult; Appetite; Astemizole; Benzimidazoles; Chlorpheniramine; Drug Evaluation; Female; Histamine H1

1987