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chlorpheniramine and Pregnancy

chlorpheniramine has been researched along with Pregnancy in 31 studies

Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"Aspirin appears to be more effective than chlorpheniramine for relief of itching in pregnancy when no rash is present."8.86WITHDRAWN: Antihistamines versus aspirin for itching in late pregnancy. ( Jewell, D; Young, G, 2010)
"Aspirin appears to be more effective than chlorpheniramine for relief of itching in pregnancy when no rash is present."8.80Antihistamines versus aspirin for itching in late pregnancy. ( Jewell, D; Young, GL, 2000)
"Aspirin appears to be more effective than chlorpheniramine for relief of itching in pregnancy when no rash is present."4.86WITHDRAWN: Antihistamines versus aspirin for itching in late pregnancy. ( Jewell, D; Young, G, 2010)
"Aspirin appears to be more effective than chlorpheniramine for relief of itching in pregnancy when no rash is present."4.80Antihistamines versus aspirin for itching in late pregnancy. ( Jewell, D; Young, GL, 2000)
"Cumulative dose-response curves for histamine induced responses in mesometrial (ME) and antimesometrial (AME) regions of uterine horns isolated from rats at 7th, 16th and 22nd days of pregnancy, were constructed."3.67Is there a prostaglandin involvement in the positive inotropic action of histamine in isolated pregnant rat uterus, apparently mediated via H1-receptors activation? ( Dveksler, G; Franchi, AM; Gimeno, AL; Gimeno, MF; Viggiano, M, 1987)
"The immunological basis for preterm labor induced by an allergic-like reaction (hypersensitivity) is reviewed."1.36Allergy-induced preterm labor after the ingestion of shellfish. ( Gomez, R; Kusanovic, JP; Lamont, RF; Muñoz, H; Romero, R; Yeo, L, 2010)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199013 (41.94)18.7374
1990's0 (0.00)18.2507
2000's13 (41.94)29.6817
2010's4 (12.90)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
De la Merced-García, DS1
Sánchez-Barrera, Á1
Hernández-Yonca, J1
Mancilla, I1
García-López, G1
Díaz, NF1
Terrazas, LI1
Molina-Hernández, A1
Ferreres-García, K1
de León-Luis, J1
Seoane, E1
García-Marqués, E1
Sanjuan, C1
Ortiz-Quintana, L1
Romero, R4
Kusanovic, JP1
Muñoz, H1
Gomez, R1
Lamont, RF1
Yeo, L1
Lee, EH1
Lee, SE1
Kim, YC1
Kim, SC1
Young, G1
Jewell, D2
Bytautiene, E4
Vedernikov, YP3
Saade, GR4
Garfield, RE4
Anwari, JS1
Iqbal, S1
Maul, H1
Vedernikov, Y1
WESTON, GA1
BISLEY, BL1
KAY, CR1
Ng, CV1
Charlton, BG1
Källén, B1
Robert-Gnansia, E1
Matsuyama, K1
Ichikawa, T1
Nitta, Y1
Ikoma, Y1
Ishimura, K1
Horio, S1
Fukui, H1
Samieh-Tucker, A1
Rupasinghe, M1
Bomzon, L1
Young, GL1
Bealer, SL1
Crowley, WR1
Read, MD1
Schuller, DE1
Turkewitz, D1
Eyre, RW1
Stanley, JR1
Viggiano, M1
Franchi, AM1
Dveksler, G1
Gimeno, MF1
Gimeno, AL1
Messinis, IE1
Souvatzoglou, A1
Fais, N1
Lolis, D1
Naranjo, P1
de Naranjo, E1
Mehta, BC1
Jhaveri, K1
Patel, JC1
Osman, OH1
Ismail, M1
el-Asmar, MF1
Ibrahim, SA1
Grumbach, MM1
Kaplan, SL1
Sciarra, JJ1
Burr, IM1
Widelock, D1
Martorana, NF1
Schaeffer, M1

Reviews

3 reviews available for chlorpheniramine and Pregnancy

ArticleYear
WITHDRAWN: Antihistamines versus aspirin for itching in late pregnancy.
    The Cochrane database of systematic reviews, 2010, Nov-10, Issue:11

    Topics: Antipruritics; Aspirin; Chlorpheniramine; Female; Histamine H1 Antagonists; Humans; Pregnancy; Pregn

2010
Antihistamines versus aspirin for itching in late pregnancy.
    The Cochrane database of systematic reviews, 2000, Issue:2

    Topics: Antipruritics; Aspirin; Chlorpheniramine; Female; Histamine H1 Antagonists; Humans; Pregnancy; Pregn

2000
Adverse effects of antihistamines.
    Postgraduate medicine, 1986, Feb-01, Volume: 79, Issue:2

    Topics: Adolescent; Adult; Aged; Asthma; Brompheniramine; Central Nervous System; Child, Preschool; Chlorphe

1986

Trials

1 trial available for chlorpheniramine and Pregnancy

ArticleYear
A limited trial of Saffan in the dog.
    The Journal of small animal practice, 1981, Volume: 22, Issue:12

    Topics: Anesthesia, Intravenous; Anesthetics; Animals; Cesarean Section; Chlorpheniramine; Clinical Trials a

1981

Other Studies

27 other studies available for chlorpheniramine and Pregnancy

ArticleYear
Increased Nuclear FOXP2 Is Related to Reduced Neural Stem Cell Number and Increased Neurogenesis in the Dorsal Telencephalon of Embryos of Diabetic Rats through Histamine H
    Cells, 2023, 02-03, Volume: 12, Issue:3

    Topics: Animals; Chlorpheniramine; Diabetes Mellitus, Experimental; Female; Forkhead Transcription Factors;

2023
[A case study of anaphylaxis in a pregnant woman].
    Ginecologia y obstetricia de Mexico, 2014, Volume: 82, Issue:3

    Topics: Adult; Anaphylaxis; Anti-Allergic Agents; Cardiotocography; Chlorpheniramine; Emergency Service, Hos

2014
Allergy-induced preterm labor after the ingestion of shellfish.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2010, Volume: 23, Issue:4

    Topics: Adult; Animals; Anti-Allergic Agents; Betamethasone; Chlorpheniramine; Female; Food Hypersensitivity

2010
Grover's disease associated with pregnancy.
    The Journal of dermatology, 2010, Volume: 37, Issue:4

    Topics: Acantholysis; Adult; Chlorpheniramine; Female; Humans; Prednisolone; Pregnancy; Pregnancy Complicati

2010
Effect of histamine on phasic and tonic contractions of isolated uterine tissue from pregnant women.
    American journal of obstetrics and gynecology, 2003, Volume: 188, Issue:3

    Topics: Chlorpheniramine; Cimetidine; Dose-Response Relationship, Drug; Female; Histamine; Histamine H1 Anta

2003
Antihistamines and potentiation of opioid induced sedation and respiratory depression.
    Anaesthesia, 2003, Volume: 58, Issue:5

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Chlorpheniramine; Drug Syner

2003
Proteinase-activated receptor-2 activation induces uterine contractility in term pregnant rats that is not dependent on mast cell activation and cyclo-oxygenase products.
    American journal of obstetrics and gynecology, 2003, Volume: 188, Issue:6

    Topics: Animals; Chlorpheniramine; Cimetidine; Cromolyn Sodium; Dose-Response Relationship, Drug; Female; Hi

2003
Control of nausea and vomiting; observations on the use of chlortrimeton (chlorprophenpyridamine maleate) syrup.
    California medicine, 1957, Volume: 86, Issue:6

    Topics: Anesthesia, Local; Anesthetics, Local; Anti-Allergic Agents; Autoimmune Diseases; Carcinoma; Chlorph

1957
ANTI-EMETIC EFFECTS OF A PHENOTHIAZINE COMPARED WITH AN ANTIHISTAMINE.
    The Practitioner, 1964, Volume: 193

    Topics: Anti-Allergic Agents; Antiemetics; Biomedical Research; Chlorpheniramine; Family Practice; Female; F

1964
Degranulation of uterine mast cell modifies contractility of isolated myometrium from pregnant women.
    American journal of obstetrics and gynecology, 2004, Volume: 191, Issue:5

    Topics: Cell Degranulation; Chlorpheniramine; Cimetidine; Cromolyn Sodium; Female; Histamine H1 Antagonists;

2004
Hypersensitivity reactions to oxaliplatin in two asian patients.
    The Annals of pharmacotherapy, 2005, Volume: 39, Issue:6

    Topics: Adult; Anti-Allergic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant;

2005
Self-management and pregnancy--safe interventions for panic, phobia and other anxiety-disorders might include over-the-counter (OTC) 'SSRI' antihistamines such as diphenhydramine and chlorpheniramine.
    Acta psychiatrica Scandinavica, 2005, Volume: 112, Issue:4

    Topics: Adult; Chlorpheniramine; Diphenhydramine; Female; Histamine H1 Antagonists; Humans; Nonprescription

2005
Maternal drug use, fertility problems, and infant craniostenosis.
    The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2005, Volume: 42, Issue:6

    Topics: Adult; Anti-Allergic Agents; Anti-Anxiety Agents; Anti-Infective Agents, Urinary; Anticonvulsants; C

2005
Localized expression of histamine H1 receptors in syncytiotrophoblast cells of human placenta.
    Journal of pharmacological sciences, 2006, Volume: 102, Issue:3

    Topics: Adult; Animals; Blotting, Western; Chlorpheniramine; CHO Cells; Chorionic Gonadotropin; Chorionic Vi

2006
Anaesthesia for caesarean section in a patient with acute generalised pustular psoriasis.
    International journal of obstetric anesthesia, 2007, Volume: 16, Issue:4

    Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Gener

2007
The use of newer asthma and allergy medications during pregnancy. The American College of Obstetricians and Gynecologists (ACOG) and The American College of Allergy, Asthma and Immunology (ACAAI).
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2000, Volume: 84, Issue:5

    Topics: Abnormalities, Drug-Induced; Acetates; Administration, Inhalation; Administration, Intranasal; Admin

2000
Histaminergic control of oxytocin release in the paraventricular nucleus during lactation in rats.
    Experimental neurology, 2001, Volume: 171, Issue:2

    Topics: Animals; Chlorpheniramine; Female; Histamine H1 Antagonists; Histamine H2 Antagonists; Histamine Rel

2001
Endogenous mast cell degranulation modulates cervical contractility in the guinea pig.
    American journal of obstetrics and gynecology, 2002, Volume: 186, Issue:3

    Topics: Animals; Cell Degranulation; Cervix Uteri; Chlorpheniramine; Cimetidine; Dose-Response Relationship,

2002
A new hypothesis of itching in pregnancy.
    The Practitioner, 1977, Volume: 218, Issue:1308

    Topics: Aspirin; Chlorpheniramine; Female; Humans; Liver Function Tests; Models, Biological; Pregnancy; Preg

1977
Maternal pemphigus foliaceus with cell surface antibody bound in neonatal epidermis.
    Archives of dermatology, 1988, Volume: 124, Issue:1

    Topics: Adult; Chlorpheniramine; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Pemphigus; Pregna

1988
Is there a prostaglandin involvement in the positive inotropic action of histamine in isolated pregnant rat uterus, apparently mediated via H1-receptors activation?
    Prostaglandins, leukotrienes, and medicine, 1987, Volume: 28, Issue:3

    Topics: Alprostadil; Animals; Aspirin; Chlorpheniramine; Cimetidine; Dinoprost; Dinoprostone; Female; Histam

1987
Histamine H1 receptor participation in the control of prolactin secretion in postpartum.
    Journal of endocrinological investigation, 1985, Volume: 8, Issue:2

    Topics: Adolescent; Adult; Breast Feeding; Chlorpheniramine; Female; Humans; Postpartum Period; Pregnancy; P

1985
Embryotoxic effects of antihistamines.
    Arzneimittel-Forschung, 1968, Volume: 18, Issue:2

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Body Weight; Chlorpheniramine; Diphenhy

1968
Role of antihistaminics in preventing systemic side effects of iron-dextran therapy.
    Indian journal of medical sciences, 1970, Volume: 24, Issue:4

    Topics: Anemia, Hypochromic; Aspirin; Chlorpheniramine; Female; Histamine H1 Antagonists; Humans; Iron-Dextr

1970
Effect on the rat uterus of the venom from the scorpion Leiurus quinquestriatus.
    Toxicon : official journal of the International Society on Toxinology, 1972, Volume: 10, Issue:4

    Topics: Animals; Atropine; Chlorpheniramine; Cocaine; Diphenhydramine; Estrus; Female; Hexamethonium Compoun

1972
Chorionic growth hormone-prolactin (CGP): secretion, disposition, biologic activity in man, and postulated function as the "growth hormone" of the 2d half of pregnancy.
    Annals of the New York Academy of Sciences, 1968, Feb-05, Volume: 148, Issue:2

    Topics: Amniotic Fluid; Biological Transport, Active; Chlorpheniramine; Choriocarcinoma; Dwarfism, Pituitary

1968
The effect of pertussis vaccine on fetal wastage in mice. II. The sparing effect of glucose.
    American journal of public health and the nation's health, 1966, Volume: 56, Issue:9

    Topics: Animals; Chlorpheniramine; Female; Fetal Death; Fetus; Glucose; Mice; Pertussis Vaccine; Pregnancy;

1966