chlorpheniramine has been researched along with Otitis Media in 11 studies
Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.
Otitis Media: Inflammation of the MIDDLE EAR including the AUDITORY OSSICLES and the EUSTACHIAN TUBE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-four children with secretory otitis media awaiting operation for removal of adenoids were studied to investigate the effects of an antihistamine/nasal decongestant combination ('Dimotapp') and sodium cromoglycate nasal drops on the histamine content of adenoids, middle ear fluid and nasopharyngeal secretions." | 9.05 | The effect of an anti-allergic, nasal decongestant combination ('Dimotapp') and sodium cromoglycate nose drops on the histamine content of adenoids, middle ear fluid and nasopharyngeal secretions of children with secretory otitis media. ( Church, MK; Collins, MP, 1983) |
| "In a double-blind, randomized trial of 553 infants and children who had otitis media with effusion ("secretory" otitis media), we compared the efficacy of a four-week course of an oral decongestant-antihistamine combination (pseudoephedrine hydrochloride, 4 mg per kilogram of body weight per day, and chlorpheniramine maleate, 0." | 5.05 | Lack of efficacy of a decongestant-antihistamine combination for otitis media with effusion ("secretory" otitis media) in children. Results of a double-blind, randomized trial. ( Bluestone, CD; Cantekin, EI; Fria, TJ; Mandel, EM; Paradise, JL; Rockette, HE; Rogers, KD; Stool, SE, 1983) |
| "Twenty-four children with secretory otitis media awaiting operation for removal of adenoids were studied to investigate the effects of an antihistamine/nasal decongestant combination ('Dimotapp') and sodium cromoglycate nasal drops on the histamine content of adenoids, middle ear fluid and nasopharyngeal secretions." | 5.05 | The effect of an anti-allergic, nasal decongestant combination ('Dimotapp') and sodium cromoglycate nose drops on the histamine content of adenoids, middle ear fluid and nasopharyngeal secretions of children with secretory otitis media. ( Church, MK; Collins, MP, 1983) |
| "Clinical outcomes and recurrence rates did not differ significantly with treatment." | 2.71 | A randomized, placebo-controlled trial of the effect of antihistamine or corticosteroid treatment in acute otitis media. ( Baldwin, CD; Chonmaitree, T; Freeman, DH; Heikkinen, T; McCormick, DP; Saeed, K; Uchida, T, 2003) |
| "In a randomized study, 53 children were treated for acute otitis media with antibiotics and either Naldecon or placebo." | 2.65 | The use of an antihistamine-decongestant in conjunction with an anti-infective drug in the treatment of acute otitis media. ( Higbee, MD; Moran, DM; Mutchie, KD; Paul, LD, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (90.91) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chonmaitree, T | 1 |
| Saeed, K | 1 |
| Uchida, T | 1 |
| Heikkinen, T | 1 |
| Baldwin, CD | 1 |
| Freeman, DH | 1 |
| McCormick, DP | 1 |
| Moran, DM | 1 |
| Mutchie, KD | 1 |
| Higbee, MD | 1 |
| Paul, LD | 1 |
| Cantekin, EI | 1 |
| Mandel, EM | 1 |
| Bluestone, CD | 1 |
| Rockette, HE | 1 |
| Paradise, JL | 1 |
| Stool, SE | 1 |
| Fria, TJ | 1 |
| Rogers, KD | 1 |
| Marks, NJ | 1 |
| Mills, RP | 1 |
| Shaheen, OH | 1 |
| Collins, MP | 1 |
| Church, MK | 1 |
| Lampe, RM | 1 |
| Weir, MR | 1 |
| McLeod, HL | 1 |
| Artalejo, L | 1 |
| Luciano, W | 1 |
| Wade, PH | 1 |
| O'Brien, D | 1 |
| Dusdieker, LB | 1 |
| Smith, G | 1 |
| Booth, BM | 1 |
| Woodhead, JC | 1 |
| Milavetz, G | 1 |
| Howie, VM | 1 |
| Ploussard, JH | 1 |
| Riff, LJ | 1 |
| Stickler, GB | 1 |
| Rubenstein, MM | 1 |
| McBean, JB | 1 |
| Hedgecock, LD | 1 |
| Hugstad, JA | 1 |
| Griffing, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000363] | Phase 3 | 0 participants | Interventional | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for chlorpheniramine and Otitis Media
| Article | Year |
|---|---|
Chemotherapy in ear disease.
Topics: Acute Disease; Child; Child, Preschool; Chlorpheniramine; Chronic Disease; Ear, Middle; Enterobacter | 1972 |
9 trials available for chlorpheniramine and Otitis Media
| Article | Year |
|---|---|
A randomized, placebo-controlled trial of the effect of antihistamine or corticosteroid treatment in acute otitis media.
Topics: Acute Disease; Anti-Bacterial Agents; Anti-Inflammatory Agents; Ceftriaxone; Child; Child, Preschool | 2003 |
The use of an antihistamine-decongestant in conjunction with an anti-infective drug in the treatment of acute otitis media.
Topics: Acoustic Impedance Tests; Adolescent; Amoxicillin; Benzhydryl Compounds; Child; Child, Preschool; Ch | 1982 |
Lack of efficacy of a decongestant-antihistamine combination for otitis media with effusion ("secretory" otitis media) in children. Results of a double-blind, randomized trial.
Topics: Child; Child, Preschool; Chlorpheniramine; Clinical Trials as Topic; Double-Blind Method; Drug Combi | 1983 |
Cotrimoxazole in the treatment of serous otitis. A follow-up report.
Topics: Child; Chlorpheniramine; Clinical Trials as Topic; Drug Combinations; Follow-Up Studies; Humans; Mul | 1983 |
The effect of an anti-allergic, nasal decongestant combination ('Dimotapp') and sodium cromoglycate nose drops on the histamine content of adenoids, middle ear fluid and nasopharyngeal secretions of children with secretory otitis media.
Topics: Adenoids; Child; Chlorpheniramine; Cromolyn Sodium; Drug Combinations; Ear, Middle; Exudates and Tra | 1983 |
A clinical trial of antihistamine, decongestant, or placebo in antibiotic-treated acute otitis media followed with pneumatic otoscopy and impedance tympanometry.
Topics: Acoustic Impedance Tests; Acute Disease; Ampicillin; Child, Preschool; Chlorpheniramine; Clinical Tr | 1981 |
The long-term outcome of nonsuppurative otitis media with effusion.
Topics: Child; Child, Preschool; Chlorpheniramine; Clinical Trials as Topic; Double-Blind Method; Ephedrine; | 1985 |
Efficacy of fixed combination antibiotics versus separate components in otitis media. Effectiveness of erythromycin estrolate, triple sulfonamide, ampicillin, erythromycin estolate- triple sulfonamide, and placebo in 280 patients with acute otitis media u
Topics: Acetaminophen; Acute Disease; Ampicillin; Child, Preschool; Chlorpheniramine; Drug Combinations; Ery | 1972 |
Treatment of acute otitis media in children. IV. A fourth clinical trial.
Topics: Acute Disease; Child; Child, Preschool; Chlorpheniramine; Drug Therapy, Combination; Female; Humans; | 1967 |
1 other study available for chlorpheniramine and Otitis Media
| Article | Year |
|---|---|
Naldecon claims disputed.
Topics: Benzhydryl Compounds; Chlorpheniramine; Drug Combinations; Humans; Multi-Ingredient Cold, Flu, and A | 1983 |