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chlorpheniramine and Mydriasis

chlorpheniramine has been researched along with Mydriasis in 2 studies

Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.

Mydriasis: Dilation of pupils to greater than 6 mm combined with failure of the pupils to constrict when stimulated with light. This condition may occur due to injury of the pupillary fibers in the oculomotor nerve, in acute angle-closure glaucoma, and in ADIE SYNDROME.

Research Excerpts

ExcerptRelevanceReference
"This study was designed to determine if the histamine H3 receptor agonist R-alpha-methylhistamine would play a role in modulation of sympathetically evoked mydriasis in anesthetized rats, and if so, to ascertain the specific receptor subtype(s) involved."3.71Histamine H3 receptor-mediated inhibition of sympathetically evoked mydriasis in rats. ( Kawarai, M; Koss, MC; Yu, Y, 2001)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gelmi, C1
Ceccuzzi, R1
Yu, Y1
Kawarai, M1
Koss, MC1

Trials

1 trial available for chlorpheniramine and Mydriasis

ArticleYear
Mydriatic effect of ocular decongestants studied by pupillography.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1994, Volume: 208, Issue:5

    Topics: Adult; Chlorpheniramine; Drug Synergism; Female; Humans; Imidazoles; Intraocular Pressure; Male; Myd

1994

Other Studies

1 other study available for chlorpheniramine and Mydriasis

ArticleYear
Histamine H3 receptor-mediated inhibition of sympathetically evoked mydriasis in rats.
    European journal of pharmacology, 2001, May-04, Volume: 419, Issue:1

    Topics: Animals; Chlorpheniramine; Cimetidine; Dimaprit; Dose-Response Relationship, Drug; Electric Stimulat

2001