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chlorpheniramine and Muscle Relaxation

chlorpheniramine has been researched along with Muscle Relaxation in 14 studies

Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
"Treatment with cimetidine attenuated the sustained relaxation, whereas chlorpheniramine or indomethacin depressed the phasic relaxation."1.29Histamine actions in dog retinal central arteries as compared to those in middle cerebral and temporal arteries. ( Kani, K; Kitamura, Y; Okamura, T; Toda, N, 1995)
"Treatment with indomethacin inhibited the phasic component in the strips with endothelium, but did not influence the relaxation after endothelium denudation."1.28[Mechanisms of histamine-induced relaxation in isolated dog mesenteric arteries and veins]. ( Toda, N; Yamazaki, M, 1992)
"Histamine was infused at 1."1.28Developmental changes in effects of histamine on segmental pulmonary vascular resistances. ( Chu, K; Clément de Cléty, S; Gordon, JB, 1991)
"05) shifts to the right of the histamine dose-response curve in normal physiological salt solution (PSS)."1.27Differential effects of adenosine and verapamil on histamine vascular contractions. ( Merrill, GF; Tozzi, CA, 1986)
" Cimetidine shifted the dose-response curve for histamine to the right, but chlorpheniramine did not alter the response."1.27Mechanisms of histamine-induced relaxation in isolated monkey and dog coronary arteries. ( Toda, N, 1986)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19904 (28.57)18.7374
1990's6 (42.86)18.2507
2000's2 (14.29)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boskabady, MH3
Ghasemzadeh Rahbardar, M1
Nemati, H1
Esmaeilzadeh, M1
Tabanfar, H1
Ramazani, M1
Tabei, T1
Satoh, H1
Inui, J1
Ortiz, JL2
Labat, C2
Norel, X2
Gorenne, I2
Verley, J2
Brink, C2
Kitamura, Y1
Okamura, T2
Kani, K1
Toda, N4
Kanamaru, M1
Iwase, M1
Homma, I1
Ayajiki, K1
Yamazaki, M1
Gordon, JB1
Clément de Cléty, S1
Chu, K1
Tanaka, DT1
Grunstein, MM1
Tozzi, CA1
Merrill, GF1

Other Studies

14 other studies available for chlorpheniramine and Muscle Relaxation

ArticleYear
Inhibitory effect of Crocus sativus (saffron) on histamine (H1) receptors of guinea pig tracheal chains.
    Die Pharmazie, 2010, Volume: 65, Issue:4

    Topics: Algorithms; Animals; Chlorpheniramine; Crocus; Dose-Response Relationship, Drug; Ethanol; Guinea Pig

2010
Effect of Zataria multiflora Bois L. on histamine (H1) receptor of guinea pig tracheal chains.
    Indian journal of experimental biology, 2011, Volume: 49, Issue:9

    Topics: Animals; Chlorpheniramine; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Histamine H1 An

2011
Relaxant effects of different fractions of essential oil from Carum copticum on guinea pig tracheal chains.
    Phytotherapy research : PTR, 2003, Volume: 17, Issue:10

    Topics: Animals; Bronchodilator Agents; Carum; Chlorpheniramine; Dose-Response Relationship, Drug; Ethanol;

2003
Endothelial cell-dependent relaxation and contraction induced by histamine in the isolated guinea-pig pulmonary artery.
    European journal of pharmacology, 1984, Jan-27, Volume: 97, Issue:3-4

    Topics: Animals; Chlorpheniramine; Endothelium; Female; Guinea Pigs; Histamine; In Vitro Techniques; Male; M

1984
Response to anti-human IgE in human pulmonary arteries. Regulation by endothelium.
    The American review of respiratory disease, 1993, Volume: 147, Issue:4

    Topics: Arginine; Chlorpheniramine; Endothelium, Vascular; Epoprostenol; Histamine Release; Humans; Immunoen

1993
Histamine actions in dog retinal central arteries as compared to those in middle cerebral and temporal arteries.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1995,Summer, Volume: 11, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cerebral Arteries; Chlorpheniramine; Cimetidine; D

1995
Neuronal histamine release elicited by hyperthermia mediates tracheal dilation and pressor response.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 280, Issue:6

    Topics: Animals; Blood Pressure; Body Temperature; Chlorpheniramine; Fever; Histamine; Histamine Antagonists

2001
Involvement of nitric oxide in endothelium-dependent, phasic relaxation caused by histamine in monkey cerebral arteries.
    Japanese journal of pharmacology, 1992, Volume: 60, Issue:4

    Topics: Animals; Arginine; Basilar Artery; Cerebral Arteries; Chlorpheniramine; Cimetidine; Dinoprost; Endot

1992
Histamine receptors on human isolated pulmonary arterial muscle preparations: effects of endothelial cell removal and nitric oxide inhibitors.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2

    Topics: Arginine; Burimamide; Chlorpheniramine; Cimetidine; Dimaprit; Endothelium, Vascular; Histamine; Huma

1992
[Mechanisms of histamine-induced relaxation in isolated dog mesenteric arteries and veins].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1992, Volume: 99, Issue:1

    Topics: Animals; Chlorpheniramine; Cimetidine; Dogs; Dose-Response Relationship, Drug; Epoprostenol; Female;

1992
Developmental changes in effects of histamine on segmental pulmonary vascular resistances.
    Journal of applied physiology (Bethesda, Md. : 1985), 1991, Volume: 71, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Chlorpheniramine; Cimetidine; Histamine; Histamine H1 Antagonists;

1991
Vasoactive effects of substance P on isolated rabbit pulmonary artery.
    Journal of applied physiology (Bethesda, Md. : 1985), 1985, Volume: 58, Issue:4

    Topics: Animals; Atropine; Biomechanical Phenomena; Chlorpheniramine; Cimetidine; Dose-Response Relationship

1985
Differential effects of adenosine and verapamil on histamine vascular contractions.
    Canadian journal of physiology and pharmacology, 1986, Volume: 64, Issue:6

    Topics: Adenosine; Animals; Calcium; Chlorpheniramine; Histamine; In Vitro Techniques; Male; Muscle Relaxati

1986
Mechanisms of histamine-induced relaxation in isolated monkey and dog coronary arteries.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:2

    Topics: Animals; Benzoquinones; Chlorpheniramine; Cimetidine; Coronary Vessels; Dogs; Female; Histamine; Ind

1986