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chlorpheniramine and Mastocytosis

chlorpheniramine has been researched along with Mastocytosis in 2 studies

Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.

Mastocytosis: A rare neoplastic disorder characterized by a clonal proliferation of MAST CELLS, associated with KIT-D816 mutations, and accompanied by aberrant mast cell activation. The abnormal increase of MAST CELLS may occur in only the skin (MASTOCYTOSIS, CUTANEOUS), in extracutaneous tissues involving multiple organs (MASTOCYTOSIS, SYSTEMIC), or in solid tumors (MASTOCYTOMA).

Research Excerpts

ExcerptRelevanceReference
"It thus appears that azelastine is superior to chlorpheniramine in suppressing skin responses to histamine and morphine sulfate and in suppressing pruritus in patients with mastocytosis."9.07Comparison of azelastine and chlorpheniramine in the treatment of mastocytosis. ( Berkebile, C; Friedman, BS; Metcalfe, DD; Santiago, ML, 1993)
"It thus appears that azelastine is superior to chlorpheniramine in suppressing skin responses to histamine and morphine sulfate and in suppressing pruritus in patients with mastocytosis."5.07Comparison of azelastine and chlorpheniramine in the treatment of mastocytosis. ( Berkebile, C; Friedman, BS; Metcalfe, DD; Santiago, ML, 1993)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Friedman, BS1
Santiago, ML1
Berkebile, C1
Metcalfe, DD1
Kawano, Y1
Abe, H1
Yoshida, K1
Saitoh, F1
Kuramochi, M1
Ito, K1
Omae, T1

Trials

1 trial available for chlorpheniramine and Mastocytosis

ArticleYear
Comparison of azelastine and chlorpheniramine in the treatment of mastocytosis.
    The Journal of allergy and clinical immunology, 1993, Volume: 92, Issue:4

    Topics: Adult; Aged; Chlorpheniramine; Double-Blind Method; Drug Administration Schedule; Female; Histamine;

1993

Other Studies

1 other study available for chlorpheniramine and Mastocytosis

ArticleYear
[A case of systemic mastocytosis with flushing, palpitation and dyspnea].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1987, Volume: 76, Issue:12

    Topics: Chlorpheniramine; Cimetidine; Diagnosis, Differential; Drug Therapy, Combination; Dyspnea; Histamine

1987