chlorpheniramine has been researched along with Long QT Syndrome in 1 studies
Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.
Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Among the deleted genes, two genes have cardiac implications: PRKAG2 (OMIM #602743), associated with hypertrophic cardiomyopathy, cardiac conduction disease, and sudden death, and KCNH2 (OMIM #152427), coding for a cardiac potassium channel involved in long QT syndrome, unmasked by the chlorpheniramine treatment." | 7.91 | Long QT syndrome in chromosome 7q35q36.3 deletion involving KCNH2 gene: Warning for chlorpheniramine prescription. ( Accadia, M; Carella, M; Di Stolfo, G; Leone, MP; Maccarone, P; Mastroianno, S; Palumbo, O; Palumbo, P; Potenza, D; Russo, A; Sacco, M, 2019) |
| "Among the deleted genes, two genes have cardiac implications: PRKAG2 (OMIM #602743), associated with hypertrophic cardiomyopathy, cardiac conduction disease, and sudden death, and KCNH2 (OMIM #152427), coding for a cardiac potassium channel involved in long QT syndrome, unmasked by the chlorpheniramine treatment." | 3.91 | Long QT syndrome in chromosome 7q35q36.3 deletion involving KCNH2 gene: Warning for chlorpheniramine prescription. ( Accadia, M; Carella, M; Di Stolfo, G; Leone, MP; Maccarone, P; Mastroianno, S; Palumbo, O; Palumbo, P; Potenza, D; Russo, A; Sacco, M, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Di Stolfo, G | 1 |
| Accadia, M | 1 |
| Mastroianno, S | 1 |
| Leone, MP | 1 |
| Palumbo, O | 1 |
| Palumbo, P | 1 |
| Potenza, D | 1 |
| Maccarone, P | 1 |
| Sacco, M | 1 |
| Russo, A | 1 |
| Carella, M | 1 |
1 other study available for chlorpheniramine and Long QT Syndrome
| Article | Year |
|---|---|
Long QT syndrome in chromosome 7q35q36.3 deletion involving KCNH2 gene: Warning for chlorpheniramine prescription.
Topics: Child; Chlorpheniramine; Chromosome Deletion; Chromosomes, Human, Pair 7; DNA Copy Number Variations | 2019 |