chlorpheniramine has been researched along with Ischemia in 8 studies
Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study aimed to examine the relationship between a harmful effect of histamine and apoptosis following ischemia-reperfusion in the rat intestine." | 7.70 | Histaminergic effect on apoptosis of rat small intestinal mucosa after ischemia-reperfusion. ( Fujimoto, K; Fukuyama, K; Iwakiri, R; Kojima, M; Noda, T; Okamoto, K; Yoshida, T, 2000) |
| "We previously demonstrated that both histamine synthesis (histidine decarboxylase activity) and polyamine synthesis (ornithine decarboxylase activity) increased in the rat intestinal mucosa after ischemia-reperfusion, whereas the relationship between these two factors remains unclear." | 7.69 | Newly synthesized histamine accelerates ornithine decarboxylase activity in rat intestinal mucosa after ischemia-reperfusion. ( Fujimoto, K; Gotoh, Y; Iwakiri, R; Koyama, T; Matsunaga, C; Morita, H; Ogata, S; Sakata, Y; Tsunada, S, 1995) |
| "This study aimed to examine the relationship between a harmful effect of histamine and apoptosis following ischemia-reperfusion in the rat intestine." | 3.70 | Histaminergic effect on apoptosis of rat small intestinal mucosa after ischemia-reperfusion. ( Fujimoto, K; Fukuyama, K; Iwakiri, R; Kojima, M; Noda, T; Okamoto, K; Yoshida, T, 2000) |
| "We previously demonstrated that both histamine synthesis (histidine decarboxylase activity) and polyamine synthesis (ornithine decarboxylase activity) increased in the rat intestinal mucosa after ischemia-reperfusion, whereas the relationship between these two factors remains unclear." | 3.69 | Newly synthesized histamine accelerates ornithine decarboxylase activity in rat intestinal mucosa after ischemia-reperfusion. ( Fujimoto, K; Gotoh, Y; Iwakiri, R; Koyama, T; Matsunaga, C; Morita, H; Ogata, S; Sakata, Y; Tsunada, S, 1995) |
| " Rats were pretreated with alpha-fluoromethylhistidine (a suicide inhibitor of histidine decarboxylase, a synthesizing enzyme of histamine), H1-receptor antagonist (chlorpheniramine maleate), H2-antagonist (cimetidine), or H3-antagonist (thioperamide) before ischemia-reperfusion (I/R)." | 3.69 | Histaminergic control of mucosal repair in the small intestine. ( Fujimoto, K; Gotoh, Y; Ogata, S; Ohyama, T; Okamoto, K; Ootani, A; Sakata, T; Tsunada, S, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujimoto, K | 3 |
| Sakata, Y | 1 |
| Tsunada, S | 2 |
| Koyama, T | 1 |
| Morita, H | 1 |
| Ogata, S | 2 |
| Matsunaga, C | 1 |
| Gotoh, Y | 2 |
| Iwakiri, R | 2 |
| Ohyama, T | 1 |
| Ootani, A | 1 |
| Okamoto, K | 2 |
| Sakata, T | 1 |
| Fu, LW | 1 |
| Pan, HL | 1 |
| Longhurst, JC | 1 |
| Yoshida, T | 1 |
| Noda, T | 1 |
| Kojima, M | 1 |
| Fukuyama, K | 1 |
| Kaidbey, KH | 1 |
| Kligman, AM | 1 |
| Santiago-Delpín, EA | 1 |
| Vivoni, V | 1 |
| Suárez, A | 1 |
| Román-Franco, AA | 1 |
| Polizzi, M | 1 |
| Bartoli, GM | 1 |
| Gaudiano, A | 1 |
| Montorsi, F | 1 |
| Petti, G | 1 |
| Tartarini, S | 1 |
| DiPasquale, G | 1 |
| Steinetz, BG | 1 |
8 other studies available for chlorpheniramine and Ischemia
| Article | Year |
|---|---|
Newly synthesized histamine accelerates ornithine decarboxylase activity in rat intestinal mucosa after ischemia-reperfusion.
Topics: Animals; Chlorpheniramine; Cimetidine; Histamine; Histamine Antagonists; Histidine Decarboxylase; In | 1995 |
Histaminergic control of mucosal repair in the small intestine.
Topics: Animals; Biological Transport; Chlorpheniramine; Cimetidine; Enzyme Inhibitors; Histamine; Histamine | 1995 |
Endogenous histamine stimulates ischemically sensitive abdominal visceral afferents through H1 receptors.
Topics: Abdomen; Afferent Pathways; Animals; Bile Ducts; Blood Pressure; Cats; Chlorpheniramine; Dimaprit; D | 1997 |
Histaminergic effect on apoptosis of rat small intestinal mucosa after ischemia-reperfusion.
Topics: Animals; Apoptosis; Chlorpheniramine; Cimetidine; Guanidines; Histamine; Histamine Antagonists; Inte | 2000 |
Clinical and histological study of coal tar phototoxicity in humans.
Topics: Adrenal Cortex Hormones; Adult; Arm; Chlorpheniramine; Coal Tar; Histamine H1 Antagonists; Humans; I | 1977 |
Protection of organs during experimental ischemia.
Topics: Ampicillin; Animals; Chlorpheniramine; Dogs; Hindlimb; Intestine, Small; Ischemia; Methylprednisolon | 1978 |
[Effect of some neuroleptic drugs and antihistaminics on the changes of the enzyme pattern induced by ischemia in the rat liver].
Topics: Animals; Cathepsins; Chlorpheniramine; Chlorpromazine; Electron Transport Complex IV; Galactosidases | 1968 |
Chemoprophylaxis of experimental post ischemic edema of the rat paw.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antidepressive Agents; Antimalarials; Autonomic Agent | 1970 |