chlorpheniramine has been researched along with Inflammation in 18 studies
Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The econazole pleurisy development is monophasic and its peak value occurs between 8 and 12 hr after econazole injection." | 5.27 | Some characteristics of econazole-induced pleurisy in rats. ( Hanada, S; Hirano, MT; Oga, S, 1985) |
| " Histamine is a major mediator released by mast cells in allergic inflammation and response." | 4.12 | Histamine induced high mobility group box-1 release from vascular endothelial cells through H ( Gao, S; Ku, W; Liu, K; Nishibori, M; Qiao, H; Teshigawara, K; Wake, H; Wang, D, 2022) |
| " The sensory neuropeptide substance P (SP), when released from sensory nerves, has been implicated in the development of neurogenic inflammation." | 3.69 | Substance P-induced inflammatory responses in guinea-pig skin: the effect of specific NK1 receptor antagonists and the role of endogenous mediators. ( Nourshargh, S; Walsh, DT; Weg, VB; Williams, TJ, 1995) |
| "In order to assess the role of inflammation and its components in spontaneous cure of Strongyloides ratti infestation, rats were treated with non-steroid anti-inflammatory agents (indometacin; sodium salicylate) or with antagonists of certain mediators (dexchlorpheniramin; cyproheptadin, promethazin)." | 3.67 | [The role of inflammation in the spontaneous elimination of Strongyloides ratti infestation]. ( Bailenger, J; Lacassie, A, 1986) |
| "The econazole pleurisy development is monophasic and its peak value occurs between 8 and 12 hr after econazole injection." | 1.27 | Some characteristics of econazole-induced pleurisy in rats. ( Hanada, S; Hirano, MT; Oga, S, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (61.11) | 18.7374 |
| 1990's | 4 (22.22) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, S | 1 |
| Liu, K | 1 |
| Ku, W | 1 |
| Wang, D | 1 |
| Wake, H | 1 |
| Qiao, H | 1 |
| Teshigawara, K | 1 |
| Nishibori, M | 1 |
| FRANK, L | 1 |
| RAPP, Y | 1 |
| BIRO, L | 1 |
| GLICKMAN, FS | 1 |
| ARRIGONIMARTELLI, E | 1 |
| CONTI, I | 1 |
| COHEN, SG | 1 |
| SAPP, TM | 1 |
| LASKIN, DM | 1 |
| KOLODNY, SC | 1 |
| DORFMAN, RI | 1 |
| DORFMAN, AS | 1 |
| Figueroa, XF | 1 |
| Alviña, K | 1 |
| Martínez, AD | 1 |
| Garcés, G | 1 |
| Rosemblatt, M | 1 |
| Boric, MP | 1 |
| Sáez, JC | 1 |
| Liu, T | 1 |
| Bai, ZT | 1 |
| Pang, XY | 1 |
| Chai, ZF | 1 |
| Jiang, F | 1 |
| Ji, YH | 1 |
| Lloret, S | 1 |
| Moreno, JJ | 1 |
| Walsh, DT | 1 |
| Weg, VB | 1 |
| Williams, TJ | 1 |
| Nourshargh, S | 1 |
| Forteza, R | 1 |
| Lauredo, IT | 1 |
| Burch, R | 1 |
| Abraham, WM | 1 |
| Lampa, E | 1 |
| Apolito, A | 1 |
| Russo, G | 1 |
| Pedone, P | 1 |
| Alise, G | 1 |
| Snyman, JR | 1 |
| Sommers, DK | 1 |
| Gregorowski, MD | 1 |
| Boraine, H | 1 |
| Evans, TW | 1 |
| Rogers, DF | 1 |
| Aursudkij, B | 1 |
| Chung, KF | 1 |
| Barnes, PJ | 1 |
| Archer, CB | 1 |
| MacDonald, DM | 1 |
| Morley, J | 1 |
| Page, CP | 1 |
| Paul, W | 1 |
| Sanjar, S | 1 |
| Bailenger, J | 1 |
| Lacassie, A | 1 |
| Hanada, S | 1 |
| Oga, S | 1 |
| Hirano, MT | 1 |
| Pircio, AW | 1 |
| Groskinsky, EJ | 1 |
1 trial available for chlorpheniramine and Inflammation
| Article | Year |
|---|---|
Effect of cetirizine, ketotifen and chlorpheniramine on the dynamics of the cutaneous hypersensitivity reaction: a comparative study.
Topics: Basophils; Cetirizine; Chlorpheniramine; Dermatitis, Contact; Double-Blind Method; Eosinophils; Hist | 1992 |
17 other studies available for chlorpheniramine and Inflammation
| Article | Year |
|---|---|
Histamine induced high mobility group box-1 release from vascular endothelial cells through H
Topics: Anaphylaxis; Animals; Chlorpheniramine; Chromatin; Endothelial Cells; Epinephrine; Histamine; Histam | 2022 |
INFLAMMATION MEDIATORS AND THE INFLAMMATORY REACTION.
Topics: Anti-Allergic Agents; Bradykinin; Capillary Permeability; Chlorpheniramine; Cyproheptadine; Fluoresc | 1964 |
[RESEARCH ON A NEW METHOD OF EXPERIMENTAL INFLAMMATION: SUBPLANTAR EDEMA CAUSED BY CARRAGEENIN].
Topics: Adrenalectomy; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Carrageenan; Chlorpheniramine; Ch | 1964 |
POLYSACCHARIDE EFFECTS SIMULATING HYPERSENSITIVITY RESPONSES IN THE RABBIT.
Topics: Antigen-Antibody Reactions; Blood Coagulation; Blood Group Antigens; Chlorpheniramine; Eosinophils; | 1964 |
INHIBITION OF EXUDATE PRODUCTION BY ANTI-INFLAMMATORY DRUGS.
Topics: Anti-Inflammatory Agents; Chlorpheniramine; Chlorpromazine; Deoxyribonuclease I; Exudates and Transu | 1965 |
ANTI-INFLAMMATORY ACTIVITY ON NONSTEROIDAL AGENTS IN A RAT GRANULOMA ASSAY.
Topics: Adrenalectomy; Anti-Inflammatory Agents; Antipyrine; Biological Assay; Chlorpheniramine; Granuloma; | 1965 |
Histamine reduces gap junctional communication of human tonsil high endothelial cells in culture.
Topics: Cells, Cultured; Chlorpheniramine; Coloring Agents; Connexin 43; Cyclic AMP; Cyclooxygenase Inhibito | 2004 |
Degranulation of mast cells and histamine release involved in rat pain-related behaviors and edema induced by scorpion Buthus martensi Karch venom.
Topics: Animals; Chlorpheniramine; Cimetidine; Dose-Response Relationship, Drug; Edema; Histamine Antagonist | 2007 |
Effect of nonapeptide fragments of uteroglobin and lipocortin I on oedema and mast cell degranulation.
Topics: Animals; Annexin A1; Aristolochic Acids; Carrageenan; Cell Degranulation; Chlorpheniramine; Dexameth | 1994 |
Substance P-induced inflammatory responses in guinea-pig skin: the effect of specific NK1 receptor antagonists and the role of endogenous mediators.
Topics: Animals; Antibodies, Monoclonal; Biphenyl Compounds; Chlorpheniramine; Dihydropyridines; Dose-Respon | 1995 |
Extracellular metabolites of Pseudomonas aeruginosa produce bronchoconstriction by different mechanisms.
Topics: Administration, Inhalation; Aerosols; Airway Resistance; Animals; Atropine; Bradykinin; Bradykinin R | 1994 |
[Specific and aspecific activity of an antihistaminic of the H1 type: HC 20-511 or ketothiphen (benzo-cyclohepta-thiophenone derivative)].
Topics: Albuterol; Anaphylaxis; Animals; Anura; Bronchial Spasm; Cardiovascular System; Chlorpheniramine; Do | 1977 |
Inflammatory mediators involved in antigen-induced airway microvascular leakage in guinea pigs.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Antigens; Bronchi; Capillary | 1988 |
Effects of serum albumin, indomethacin and histamine H1-antagonists on Paf-acether-induced inflammatory responses in the skin of experimental animals and man.
Topics: Adult; Animals; Blood Proteins; Chlorpheniramine; Guinea Pigs; Histamine H1 Antagonists; Humans; Ind | 1985 |
[The role of inflammation in the spontaneous elimination of Strongyloides ratti infestation].
Topics: Animals; Chlorpheniramine; Cyproheptadine; Indomethacin; Inflammation; Male; Nematode Infections; Pr | 1986 |
Some characteristics of econazole-induced pleurisy in rats.
Topics: Animals; Carrageenan; Chlorpheniramine; Cyproheptadine; Dexamethasone; Econazole; Imidazoles; Inflam | 1985 |
Radiometric measurement of paw temperature changes associated with local inflammation.
Topics: Animals; Aspirin; Body Temperature; Chlorpheniramine; Edema; Inflammation; Radiometry; Rats; Yeasts | 1966 |