chlorpheniramine has been researched along with Hypoxia in 11 studies
Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Experimental evidence from animals suggests that the response of the pulmonary circulation to hypoxia is mediated by histamine." | 7.65 | Failure of an antagonist of histamine--chlorpheniramine--to modify the pulmonary vascular response to hypoxia in chronic bronchitis. ( Bishop, JM; Joshi, RC; Stark, RD, 1977) |
| "Experimental evidence from animals suggests that the response of the pulmonary circulation to hypoxia is mediated by histamine." | 3.65 | Failure of an antagonist of histamine--chlorpheniramine--to modify the pulmonary vascular response to hypoxia in chronic bronchitis. ( Bishop, JM; Joshi, RC; Stark, RD, 1977) |
| "Histamine was infused at 1." | 1.28 | Developmental changes in effects of histamine on segmental pulmonary vascular resistances. ( Chu, K; Clément de Cléty, S; Gordon, JB, 1991) |
| "Histamine has been alleged to have a role in the vasoconstrictor response with generalized alveolar and thus systemic hypoxia, but the role for histamine is not clear in localized alveolar hypoxia." | 1.25 | Role of histamine in the hypoxic vascular response of the lung. ( Hales, CA; Kazemi, H, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (81.82) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Condorelli, M | 1 |
| Rengo, F | 1 |
| Trimarco, B | 1 |
| Bonaduce, D | 1 |
| Iodice, F | 1 |
| Piscione, F | 1 |
| Vigorito, C | 1 |
| Marone, G | 1 |
| Ahmed, T | 1 |
| Oliver, W | 1 |
| Frank, BL | 1 |
| Robinson, MJ | 1 |
| Wanner, A | 1 |
| Howard, P | 2 |
| Barer, GR | 2 |
| Thompson, B | 1 |
| Warren, PM | 1 |
| Abbott, CJ | 1 |
| Mungall, IP | 1 |
| Tucker, A | 2 |
| Hoffman, EA | 2 |
| Weir, EK | 1 |
| Stark, RD | 1 |
| Joshi, RC | 1 |
| Bishop, JM | 1 |
| Munroe, ML | 1 |
| Reeves, JT | 1 |
| Hales, CA | 1 |
| Kazemi, H | 1 |
| Russell, PC | 1 |
| Emery, CJ | 1 |
| Nicholl, J | 1 |
| Gordon, JB | 1 |
| Clément de Cléty, S | 1 |
| Chu, K | 1 |
| Susmano, A | 2 |
| Carleton, RA | 2 |
11 other studies available for chlorpheniramine and Hypoxia
| Article | Year |
|---|---|
Mechanisms underlying pulmonary hypertension by hypoxemia.
Topics: Blood Pressure; Chlorpheniramine; Cromolyn Sodium; Histamine; Humans; Hypertension, Pulmonary; Hypox | 1984 |
Hypoxic pulmonary vasoconstriction in conscious sheep: role of mast cell degranulation.
Topics: Animals; Chlorpheniramine; Cromolyn Sodium; Cytoplasmic Granules; Female; Hemodynamics; Hypoxia; Ind | 1982 |
Factors causing and reversing vasoconstriction in unventilated lung.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blood | 1975 |
Histamine receptor antagonism does not inhibit hypoxic pulmonary vasoconstriction in dogs.
Topics: Animals; Chlorpheniramine; Dogs; Histamine; Hypoxia; Metiamide; Pulmonary Circulation; Receptors, Hi | 1977 |
Failure of an antagonist of histamine--chlorpheniramine--to modify the pulmonary vascular response to hypoxia in chronic bronchitis.
Topics: Bronchitis; Chlorpheniramine; Histamine; Humans; Hypoxia; Male; Middle Aged; Pulmonary Circulation; | 1977 |
Histamine H1- and H2-receptors in the cat and their roles during alveolar hypoxia.
Topics: Animals; Cardiac Output; Cats; Chlorpheniramine; Heart Rate; Histamine; Hypoxia; Lung; Metiamide; Pu | 1977 |
Role of histamine in the hypoxic vascular response of the lung.
Topics: Animals; Chlorpheniramine; Constriction, Pathologic; Dogs; Histamine; Hypoxia; Nitrogen; Pulmonary A | 1975 |
Interactions between hypoxic and almitrine-induced vasoconstriction in the rat lung.
Topics: Almitrine; Animals; Blood Pressure; Chlorpheniramine; Cold Temperature; Diethylcarbamazine; Dose-Res | 1992 |
Developmental changes in effects of histamine on segmental pulmonary vascular resistances.
Topics: Aging; Animals; Animals, Newborn; Chlorpheniramine; Cimetidine; Histamine; Histamine H1 Antagonists; | 1991 |
Effect of antihistaminic drugs on hypoxic pulmonary hypertension.
Topics: Animals; Blood Pressure; Chlorpheniramine; Diphenhydramine; Dogs; Female; Histamine H1 Antagonists; | 1973 |
Prevention of hypoxic pulmonary hypertension by chlorpheniramine.
Topics: Animals; Blood Pressure; Carbon Dioxide; Cardiac Output; Chlorpheniramine; Dogs; Female; Heart Rate; | 1971 |