chlorpheniramine has been researched along with Hypersensitivity in 39 studies
Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.
Hypersensitivity: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.
| Excerpt | Relevance | Reference |
|---|---|---|
| " All 43 dogs were known to be unresponsive to chlorpheniramine and the manufacturer's recommended dosage of the fatty acid supplement when either drug was used alone." | 6.67 | Nonsteroidal management of canine pruritus: chlorpheniramine and a fatty acid supplement (DVM Derm Caps) in combination, and the fatty acid supplement at twice the manufacturer's recommended dosage. ( Miller, WH; Scott, DW, 1990) |
| "We examined whether eucapnic hyperventilation with dry air produces the bronchoconstriction in anesthetized, non-sensitized rabbits and in ovalbumin sensitized rabbits." | 3.68 | Eucapnic hyperventilation-induced bronchoconstriction in rabbits. ( Horie, T; Koyama, S; Ohtsuka, A, 1992) |
| " All 43 dogs were known to be unresponsive to chlorpheniramine and the manufacturer's recommended dosage of the fatty acid supplement when either drug was used alone." | 2.67 | Nonsteroidal management of canine pruritus: chlorpheniramine and a fatty acid supplement (DVM Derm Caps) in combination, and the fatty acid supplement at twice the manufacturer's recommended dosage. ( Miller, WH; Scott, DW, 1990) |
| " The dose of chlorpheniramine (or placebo) was doubled from days 22 to 24 to assess the response to dosage increase." | 2.66 | The development of subsensitivity to chlorpheniramine. ( Long, WF; Nelson, HS; Taylor, RJ, 1985) |
| "Terfenadine was evaluated for the relief of symptoms in patients with allergic pollinosis on a double-blind basis." | 2.65 | Clinical investigation of terfenadine, a non-sedating antihistamine. ( Brandon, ML; Weiner, M, 1980) |
| " The dog was immediately treated with an intramuscular injection of a commercially available antihistamine treatment, Pen-Hista-Strep® containing a suspension of benzylpenicillin, chlorphenamine, dexamethasone, dihydrostreptomycin, and procaine at a dosage of 1 mL per 10 kg." | 1.56 | Aedes (Stegomyia) aegypti mosquito bite hypersensitivity in a dog: a case report. ( Lekouch, N; Meyer, LN; Tahir, D; Varloud, M, 2020) |
| "Cetirizine is a new anti-allergic compound with a potent, long-acting, and specific antihistaminic property." | 1.28 | Inhibition of human eosinophil chemotaxis and of the IgE-dependent stimulation of human blood platelets by cetirizine. ( Capron, A; Capron, M; De Vos, C; Joseph, M; Leprevost, C; Tomassini, M; Vorng, H, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (61.54) | 18.7374 |
| 1990's | 5 (12.82) | 18.2507 |
| 2000's | 3 (7.69) | 29.6817 |
| 2010's | 5 (12.82) | 24.3611 |
| 2020's | 2 (5.13) | 2.80 |
| Authors | Studies |
|---|---|
| Di Girolamo, A | 1 |
| Albanesi, M | 1 |
| Loconte, F | 1 |
| Di Bona, D | 1 |
| Caiaffa, MF | 1 |
| Macchia, L | 1 |
| Tahir, D | 1 |
| Meyer, LN | 1 |
| Lekouch, N | 1 |
| Varloud, M | 1 |
| Ikegawa, K | 1 |
| Suzuki, S | 1 |
| Nomura, H | 1 |
| Enokida, T | 1 |
| Yamazaki, T | 1 |
| Okano, S | 1 |
| Endo, K | 1 |
| Saito, S | 1 |
| Yamaguchi, M | 1 |
| Tahara, M | 1 |
| Giangrande, N | 1 |
| García-Menaya, JM | 1 |
| Marcos-Fernández, M | 1 |
| Cámara-Hijón, C | 1 |
| Bobadilla-González, P | 1 |
| Kuroda, W | 1 |
| Kitamura, Y | 1 |
| Mizuguchi, H | 1 |
| Miyamoto, Y | 1 |
| Kalubi, B | 1 |
| Fukui, H | 1 |
| Takeda, N | 1 |
| Yamada, Y | 1 |
| Ueda, Y | 1 |
| Nakamura, A | 1 |
| Kanayama, S | 1 |
| Tamura, R | 1 |
| Hashimoto, K | 1 |
| Matsumoto, T | 1 |
| Ishii, R | 1 |
| Alvarez-Perea, A | 1 |
| García, AP | 1 |
| Hernández, AL | 1 |
| de Barrio, M | 1 |
| Baeza, ML | 1 |
| ANDRE, AJ | 1 |
| ARNOLDSSON, H | 1 |
| PIPKORN, U | 1 |
| KEARNS, WM | 1 |
| HOFFMANN, CR | 1 |
| WECHSLER, H | 1 |
| VICKERS, M | 1 |
| KOJO, T | 1 |
| GREEN, MA | 2 |
| REICHER, J | 1 |
| SCHWARTZ, E | 1 |
| SILBERT, NE | 1 |
| Brandon, ML | 1 |
| Weiner, M | 1 |
| Delehunt, JC | 1 |
| Perruchoud, AP | 1 |
| Yerger, L | 1 |
| Marchette, B | 1 |
| Stevenson, JS | 1 |
| Abraham, WM | 1 |
| Heyneman, CA | 1 |
| Gentile, DA | 1 |
| Brown, C | 1 |
| Skoner, DP | 1 |
| Foster, AP | 1 |
| McKelvie, J | 1 |
| Cunningham, FM | 1 |
| Muler, H | 1 |
| Blum, F | 1 |
| Nagai, H | 1 |
| Osuga, K | 1 |
| Koda, A | 1 |
| Linnekogel, GG | 1 |
| Koyama, S | 1 |
| Ohtsuka, A | 1 |
| Horie, T | 1 |
| Scott, DW | 1 |
| Miller, WH | 1 |
| De Vos, C | 1 |
| Joseph, M | 1 |
| Leprevost, C | 1 |
| Vorng, H | 1 |
| Tomassini, M | 1 |
| Capron, M | 1 |
| Capron, A | 1 |
| Ahmed, T | 1 |
| King, M | 1 |
| Hand, JM | 1 |
| Schwalm, SF | 1 |
| Lewis, AJ | 1 |
| Taylor, RJ | 1 |
| Long, WF | 1 |
| Nelson, HS | 1 |
| DiPalma, JR | 1 |
| Gomez, J | 1 |
| Gomez, G | 1 |
| Delorme, P | 1 |
| Mason, DY | 1 |
| Ingram, GI | 1 |
1 review available for chlorpheniramine and Hypersensitivity
| Article | Year |
|---|---|
Histamine2-antagonists in allergic disorders.
Topics: Asthma; Chlorpheniramine; Cimetidine; Clemastine; Clinical Trials as Topic; Drug Therapy, Combinatio | 1994 |
7 trials available for chlorpheniramine and Hypersensitivity
| Article | Year |
|---|---|
Clinical investigation of terfenadine, a non-sedating antihistamine.
Topics: Benzhydryl Compounds; Chlorpheniramine; Clinical Trials as Topic; Double-Blind Method; Histamine H1 | 1980 |
In vitro modulation of platelet sodium, potassium adenosine triphosphatase enzyme activity by antiallergy drugs.
Topics: Adult; Albuterol; Blood Platelets; Chlorpheniramine; Cromolyn Sodium; Humans; Hydrocortisone; Hypers | 1993 |
[Comparative trial of 2 antihistaminics: mequitazine and dexchlorpheniramine].
Topics: Adult; Chlorpheniramine; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; | 1978 |
[The intiallergic agent Celestamine. Experience with the antiallergic agent in padiatric practice].
Topics: Adolescent; Betamethasone; Child; Child, Preschool; Chlorpheniramine; Clinical Trials as Topic; Drug | 1977 |
Nonsteroidal management of canine pruritus: chlorpheniramine and a fatty acid supplement (DVM Derm Caps) in combination, and the fatty acid supplement at twice the manufacturer's recommended dosage.
Topics: Animals; Chlorpheniramine; Dog Diseases; Dogs; Fatty Acids; Female; Hypersensitivity; Intradermal Te | 1990 |
The development of subsensitivity to chlorpheniramine.
Topics: Adolescent; Adult; Chlorpheniramine; Drug Tolerance; Female; Humans; Hypersensitivity; Male; Middle | 1985 |
Hay fever and allergy in general practice: two antihistamine drugs compared.
Topics: Adolescent; Adult; Child; Chlorpheniramine; Female; Histamine H1 Antagonists; Humans; Hypersensitivi | 1967 |
31 other studies available for chlorpheniramine and Hypersensitivity
| Article | Year |
|---|---|
Desensitization in Iron Product Allergy.
Topics: Adult; Anemia, Iron-Deficiency; Chlorpheniramine; Dexamethasone; Female; Ferric Compounds; Hematinic | 2020 |
Aedes (Stegomyia) aegypti mosquito bite hypersensitivity in a dog: a case report.
Topics: Aedes; Animals; Chlorpheniramine; Dog Diseases; Dogs; Drug Combinations; Female; Histamine Antagonis | 2020 |
Retrospective analysis of premedication, glucocorticosteroids, and H
Topics: Adult; Aged; Antineoplastic Agents, Immunological; Cetuximab; Chlorpheniramine; Dexamethasone; Femal | 2017 |
Anaphylaxis due to macrogol in a laxative solution with a positive basophil activation test.
Topics: Aged; Anaphylaxis; Basophil Degranulation Test; Chlorpheniramine; Colonoscopy; Edema; Female; Humans | 2019 |
Combination of leukotoriene receptor antagonist with antihistamine has an additive suppressive effect on the up-regulation of H1-receptor mRNA in the nasal mucosa of toluene 2,4-diisocyanate-sensitized rat.
Topics: Animals; Chlorpheniramine; Chromones; Drug Therapy, Combination; Histamine Antagonists; Hypersensiti | 2013 |
Immediate-type allergic and protease-mediated reactions are involved in scratching behaviour induced by topical application of Dermatophagoides farinae extract in NC/Nga mice.
Topics: Animals; Antibodies; Antipruritics; Behavior, Animal; Capillary Permeability; Chlorpheniramine; Comp | 2018 |
Best drugs for what ails you: the brands to buy--and those to skip.
Topics: Acetaminophen; Anesthetics, Local; Cetirizine; Chlorpheniramine; Common Cold; Cough; Dextromethorpha | 2009 |
Urticaria due to aloe vera: a new sensitizer?
Topics: Allergens; Aloe; Anti-Inflammatory Agents; Antigens, Plant; Chlorpheniramine; Erythema; Female; Hist | 2010 |
[The antihistaminic preparation chlorprophenpyridamine maleate N.N.R (allergisan); experimental and clinical studies].
Topics: Anti-Allergic Agents; Chlorpheniramine; Histamine H1 Antagonists; Hypersensitivity; Immune System Di | 1953 |
Prevention of allergic reactions to contrast medium with chlor-trimeton.
Topics: Anti-Allergic Agents; Chlorpheniramine; Contrast Media; Histamine H1 Antagonists; Hypersensitivity; | 1956 |
Allergic reactions to blood transfusion: their prevention with injectable chlor-trimeton.
Topics: Biomedical Research; Blood Transfusion; Chlorpheniramine; Histamine H1 Antagonists; Hypersensitivity | 1957 |
A comparison of benadryl and chlor-trimeton in intravenous urography.
Topics: Anti-Allergic Agents; Chlorpheniramine; Diphenhydramine; Histamine H1 Antagonists; Humans; Hypersens | 1958 |
Dextro-chlorpheniramine (polaramine) in allergy: preliminary report of 75 patients and comparison with racemic chlorpheniramine (chlor-trimeton) in 39 patients.
Topics: Anti-Allergic Agents; Chlorpheniramine; Histamine H1 Antagonists; Hypersensitivity; Immune System Di | 1959 |
[Effects of Polaramine tablets on allergic eye diseases].
Topics: Anti-Allergic Agents; Chlorpheniramine; Eye Diseases; Histamine H1 Antagonists; Hypersensitivity; Op | 1963 |
REPOSITORY POLLEN THERAPY--PLACEBO-CONTROLLED COMPARISON OF CORTICOSTEROID PROPHYLAXIS WITH AND WITHOUT ANTIHISTAMINE.
Topics: Adolescent; Adrenal Cortex Hormones; Biomedical Research; Child; Chlorpheniramine; Desensitization, | 1964 |
CRITICAL EVALUATION OF EMULSION THERAPY IN ALLERGY.
Topics: Abscess; Adrenal Cortex Hormones; Anti-Allergic Agents; Antigens; Biomedical Research; Carcinogens; | 1964 |
The symptomatic treatment of allergic diseases with chlor-trimeton.
Topics: Anaphylaxis; Chlorpheniramine; Histamine; Hypersensitivity; Immune System Diseases | 1950 |
Evaluation of chlor-trimeton maleate in hay fever and a variety of allergic diseases.
Topics: Anaphylaxis; Chlorpheniramine; Histamine; Humans; Hypersensitivity; Maleates; Rhinitis, Allergic, Se | 1950 |
The role of slow-reacting substance of anaphylaxis in the late bronchial response after antigen challenge in allergic sheep.
Topics: Airway Resistance; Animals; Antigens, Helminth; Ascaris; Bronchi; Bronchial Provocation Tests; Chlor | 1984 |
Inhibition of antigen-induced cutaneous responses of ponies with insect hypersensitivity by the histamine-1 receptor antagonist chlorpheniramine.
Topics: Animals; Antigens; Ceratopogonidae; Chlorpheniramine; Female; Histamine H1 Antagonists; Horse Diseas | 1998 |
The use of newer asthma and allergy medications during pregnancy. The American College of Obstetricians and Gynecologists (ACOG) and The American College of Allergy, Asthma and Immunology (ACAAI).
Topics: Abnormalities, Drug-Induced; Acetates; Administration, Inhalation; Administration, Intranasal; Admin | 2000 |
Newer antihistamines.
Topics: Administration, Oral; Anti-Allergic Agents; Cetirizine; Chlorpheniramine; Conscious Sedation; Diphen | 2001 |
Inhibition of hypersensitivity reactions by soluble derivatives of baicalein.
Topics: Aminophylline; Anaphylaxis; Animals; Antigens; Arthus Reaction; Asthma; Chlorpheniramine; Female; Fl | 1975 |
Eucapnic hyperventilation-induced bronchoconstriction in rabbits.
Topics: Airway Resistance; Animals; Bronchoconstriction; Carbon Dioxide; Chlorpheniramine; Histamine; Hypers | 1992 |
Inhibition of human eosinophil chemotaxis and of the IgE-dependent stimulation of human blood platelets by cetirizine.
Topics: Blood Platelets; Cetirizine; Chemotaxis, Leukocyte; Chlorpheniramine; Cytotoxicity, Immunologic; Eos | 1989 |
Suppression of pulmonary and systemic vascular histamine H2-receptors in allergic sheep.
Topics: Animals; Blood Circulation; Blood Vessels; Chlorpheniramine; Female; Histamine; Histamine Antagonist | 1986 |
Antagonism of antigen-induced contraction of isolated guinea-pig trachea by 5-lipoxygenase inhibitors.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Anima | 1986 |
Choice of antihistamines.
Topics: Chlorpheniramine; Costs and Cost Analysis; Histamine H1 Antagonists; Humans; Hypersensitivity; Hypno | 1971 |
Histamine H2 receptor antagonists.
Topics: Adenosine Monophosphate; Agranulocytosis; Anaphylaxis; Animals; Antigens; Blood Pressure; Cats; Chem | 1974 |
Localized heat urticaria.
Topics: Adult; Anesthetics, Local; Chlorpheniramine; Desensitization, Immunologic; Female; Histamine H1 Anta | 1969 |
Management of the hereditary coagulation disorders.
Topics: Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Coagulation Factors; Cerebral Hemorrhage | 1971 |