Page last updated: 2024-10-24

chlorpheniramine and Hay Fever

chlorpheniramine has been researched along with Hay Fever in 91 studies

Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.

Research Excerpts

ExcerptRelevanceReference
"A double-blind study of terfenadine and placebo in 110 patients suffering from hay fever (confirmed by skin tests) was conducted."9.05A double blind trial of terfenadine and placebo in hay fever using a substitution technique for non-responders. ( Dabrowicki, E; Huddlestone, L; Kagan, G; Kapur, TR; Wolstencroft, P, 1980)
" The effects of ingested oxatomide (30 mg/capsule) were compared with those of chlorpheniramine (5 mg/capsule) in a double-blind non-crossover study in two groups of twenty-five subjects with ragweed pollen-induced hay fever during the pollen season."9.05Effects of oxatomide compared with chlorpheniramine in allergic rhinoconjunctivitis. ( Cartier, A; Dolovich, J; Frith, PA; Hargreave, FE; Juniper, EF; Trebilcock, AL, 1981)
"A double-blind randomised parallel group study was carried out in 46 patinets to compare the effectiveness of clemastine with that of chlorpheniramine maleate in the treatment of hay fever."9.04A comparative study of clemastine ('Tavegil') and chlorpheniramine maleate in the treatment of hay fever. ( Sheriff, JM; Wallace, MG, 1976)
"A double-blind study of terfenadine and placebo in 110 patients suffering from hay fever (confirmed by skin tests) was conducted."5.05A double blind trial of terfenadine and placebo in hay fever using a substitution technique for non-responders. ( Dabrowicki, E; Huddlestone, L; Kagan, G; Kapur, TR; Wolstencroft, P, 1980)
" The effects of ingested oxatomide (30 mg/capsule) were compared with those of chlorpheniramine (5 mg/capsule) in a double-blind non-crossover study in two groups of twenty-five subjects with ragweed pollen-induced hay fever during the pollen season."5.05Effects of oxatomide compared with chlorpheniramine in allergic rhinoconjunctivitis. ( Cartier, A; Dolovich, J; Frith, PA; Hargreave, FE; Juniper, EF; Trebilcock, AL, 1981)
"A double-blind randomised parallel group study was carried out in 46 patinets to compare the effectiveness of clemastine with that of chlorpheniramine maleate in the treatment of hay fever."5.04A comparative study of clemastine ('Tavegil') and chlorpheniramine maleate in the treatment of hay fever. ( Sheriff, JM; Wallace, MG, 1976)
"Ketotifen produced seizures in a 5-year-old boy with secondary generalized epilepsy (SGE) and allergic rhinitis."3.68Proconvulsant effect of ketotifen, a histamine H1 antagonist, confirmed by the use of d-chlorpheniramine with monitoring electroencephalography. ( Iinuma, K; Onodera, K; Sakurai, E; Watanabe, T; Yanai, K; Yokoyama, H, 1993)
" There were 54 patients who reported 61 adverse events."2.71[A clinical trial to evaluate the efficacy and safety of compound pseudoephedrine hydrochloride sustained release capsule in patients with seasonal allergic rhinitis]. ( , 2004)
"Loratadine was significantly superior to placebo in 3 of 10 trials (30%), consistent with rates found in 3 pivotal group trials used for FDA approval (24%, 17%, and 0%)."2.70Single-patient drug trial methodology for allergic rhinitis. ( Del Rio, E; Rebell, G; Reitberg, DP; Weiss, SL; Zaias, N, 2002)
"Azelastine nasal spray was compared with sustained-release oral chlorpheniramine maleate and placebo for efficacy and safety in the treatment of seasonal allergic rhinitis in a double-dummy, two-center, 2-day, double-blind, randomized, dose-ranging, parallel-groups, onset and duration of action study."2.67A dose-ranging study of the efficacy and safety of azelastine nasal spray in the treatment of seasonal allergic rhinitis with an acute model. ( Benson, PM; Freitag, J; Meltzer, EO; Weiler, JM; Weiler, K; Widlitz, MD, 1994)
" There were no clinical or statistical differences in adverse effects between the two medications or between each medication and baseline."2.67Comparison of CNS adverse effects between astemizole and chlorpheniramine in children: a randomized, double-blind study. ( Feldman, W; Leikin, L; Peterson, R; Pong, AH; Shanon, A; Williams, V, 1993)
" Cards were completed hourly to evaluate symptoms of allergic rhinitis and adverse experiences caused by therapy."2.67Randomized, double-blind, parallel groups, placebo-controlled study of efficacy and safety of Rynatan in the treatment of allergic rhinitis using an acute model. ( Donnelly, A; Gellhaus, M; Weiler, JM; Weiler, K, 1990)
"Loratadine appears to be a simple, effective and safe therapy for seasonal allergic rhinitis."2.66Efficacy and safety of loratadine suspension in the treatment of children with allergic rhinitis. ( Andreoli, A; Boner, AL; Marchesi, E; Miglioranzi, P; Richelli, C, 1989)
"Dexchlorpheniramine was associated with a significant increase in the score for tiredness in contrast to terfenadine which caused no significant change."2.66Treatment of seasonal allergic rhinitis--a double blind, group comparative study of terfenadine and dexchlorpheniramine. ( Bjerrum, P; Illum, P; Johansen, LV, 1987)
"Terfenadine was well tolerated and side-effects incidence was significantly lower (p less than 0."2.66Antihistaminic treatment of allergic rhinitis: a double-blind study with terfenadine versus dexchlorpheniramine. ( Codecasa, LR; Fugazza, A; Gerosa, S; Ortolani, C; Pastorello, EA; Pravettoni, V; Zanussi, C, 1987)
"Azelastine appears to be a safe, efficacious medication for seasonal allergic rhinitis."2.66Multicenter, double-blind, multiple-dose, parallel-groups efficacy and safety trial of azelastine, chlorpheniramine, and placebo in the treatment of spring allergic rhinitis. ( Campbell, BH; Connell, JT; Diamond, L; Donnelly, A; Hamilton, LH; Hemsworth, GR; Perhach, JL; Rosenthal, RR; Weiler, JM, 1988)
" Dosage was two sprays into each nostril 4 times a day."2.66Sodium cromoglycate/chlorpheniramine and sodium cromoglycate nasal sprays in the treatment of seasonal rhinitis. ( van Niekerk, CH, 1985)
"for efficacy in controlling Ragweed Hay Fever symptoms, as well as tolerance and occurrence of adverse reactions."2.66Comparative study of the efficacy, tolerance and side-effects of dexchlorpheniramine maleate 6 mg b.i.d. with terfenadine 60 mg b.i.d. ( Del Carpio, J; Gelinas, B; Gutkowski, A; Schulz, J; Turenne, Y, 1985)
"Two treatments for summer grass pollen allergy have been studied in university students who undertook performance tests before and after treatment."2.65Performance in students with seasonal allergy. ( Bentley, S, 1980)
"In this review of the current treatment of seasonal allergic rhinitis, the clinical studies that compare these four new second-generation H1-receptor antagonists are discussed."2.38H1-receptor antagonist treatment of seasonal allergic rhinitis. ( Kaiser, HB, 1990)
"CD14+ cells prepared from patients with pollinosis to Japanese cedar pollen were stimulated with specific allergen extracted from Japanese cedar pollen (Cry j 1) in the presence of azelastine (AZE), ketotifen (KET), fexofenadine (FEX) and oxatomide (OXA) for 6 days."1.37Effect of histamine H1 receptor antagonists on TARC/CCL17 and MDC/CCL22 production from CD14+ cells induced by antigenic stimulation in vitro. ( Asano, K; Furuta, A; Hirano, K; Shoji, N; Suzaki, H, 2011)
"Thirty-five patients with hay fever evaluated cytologic smears of the nasal mucosa before and after a 2-week treatment."1.29The effect of oral drugs on the cytologic picture of nasal mucosa in hay fever. ( Tarchalska-Kryńska, B; Zawisza, E, 1993)
" To establish dose-response relationships for oral antihistamines in monkeys, we measured the suppression of wheal-and-flare reactions by two such agents, oral cetirizine (CET) 0."1.27A primate model for the evaluation of antihistamines. ( Doyle, W; Fireman, P; Skoner, D; Tanner, E, 1987)
" The cumulative results indicate that the nonsedative antihistamine terfenadine, given orally at a dosage of 60 mg twice daily, is effective in the treatment of seasonal allergic rhinitis in both adults and children."1.27The use of antihistamines for the treatment of airway disease. ( Meltzer, EO, 1988)
" In 11 patients with allergic rhinitis, ages 6 to 16 yr, we found a mean serum chlorpheniramine half-life of 13."1.26Pharmacokinetics and efficacy of chlorpheniramine in children. ( Luciuk, GH; Simons, FE; Simons, KJ, 1982)

Research

Studies (91)

TimeframeStudies, this research(%)All Research%
pre-199071 (78.02)18.7374
1990's11 (12.09)18.2507
2000's8 (8.79)29.6817
2010's1 (1.10)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Izumi, N1
Mizuguchi, H1
Umehara, H1
Ogino, S1
Fukui, H1
Shoji, N1
Asano, K1
Furuta, A1
Hirano, K1
Suzaki, H1
Reitberg, DP1
Del Rio, E1
Weiss, SL1
Rebell, G1
Zaias, N1
Hellbom, E1
Humble, M1
MULLIGAN, RM1
ZARATE, O1
QUINTEROS, HD1
EVANS, WH1
KAPLAN, H1
SHERWOOD, H1
EPSTEIN, JI1
SMELLIE, H1
FRY, L1
MACAULAY, DB1
WILSON, CW1
PLACKETT, RL1
SIEGEL, C1
SILBERT, NE1
Meltzer, EO4
Berman, GD1
Corren, J1
Pedinoff, AJ1
Doyle, G1
Waksman, JA1
Butkerait, P1
Cooper, SA1
Berlin, RG1
Wason, S1
Tsumuro, T1
Ogawa, M1
Minami, K1
Takubo, M1
Rahman, A1
Fujii, Y1
Kamei, C2
Rahman, MA1
Inoue, T1
Ishikawa, T1
Yatsuzuka, R1
Ohtsu, H1
Kagan, G1
Dabrowicki, E1
Huddlestone, L1
Kapur, TR1
Wolstencroft, P1
Lewiston, NJ1
Johnson, S1
Sloan, E1
Aguilar Angeles, D1
Navarro, BE1
Velázquez Sámano, G1
Dugue, P1
Birnbaum, J1
Poisson, A1
Charpin, J1
Brewster, BS1
Carpenter, GB1
Bunker-Soler, AL1
Nelson, HS2
Wihl, JA1
Brofeldt, S1
Grønborg, H1
Borum, P1
Mygind, N2
Munch, EP1
Søborg, M1
Nørreslet, TT1
Wheatley, D2
Simons, FE1
Luciuk, GH1
Simons, KJ1
Langrick, AF1
Wallace, MG2
Juniper, EF1
Cartier, A1
Trebilcock, AL1
Frith, PA1
Dolovich, J1
Hargreave, FE1
Bentley, S1
Weiler, JM3
Benson, PM1
Weiler, K2
Widlitz, MD1
Freitag, J1
Shanon, A1
Feldman, W1
Leikin, L1
Pong, AH1
Peterson, R1
Williams, V1
Sabbah, A2
Hassoun, S2
Le Sellin, J1
André, C2
Sicard, H2
Yokoyama, H1
Iinuma, K1
Yanai, K1
Watanabe, T1
Sakurai, E1
Onodera, K1
Lesellin, J1
Tarchalska-Kryńska, B1
Zawisza, E1
Harvey, RP1
Comer, C1
Sanders, B1
Westley, R1
Marsh, W1
Shapiro, H1
Wiener, M1
Prenner, BM1
Chervinsky, P1
Hampel, FC1
Howland, WC1
Lawrence, M1
Munk, ZM1
Ratner, PH1
Seltzer, JM1
Settipane, GA1
Lorber, RR1
Harrison, JE1
Muler, H2
Blum, F2
Cohen, BM1
Todd, G1
Hopkins, P1
Maclay, WP1
Thach, BT1
Chase, TN1
Bosma, JF1
Thomas, JS2
Heurich, AE2
Ralph, JW1
Crane, R2
Shepherd, DA2
Huh, C1
Posey, WC1
Sheriff, JM1
Wilson, JA1
Walker, SR1
Cohan, RH1
Bloom, FL1
Rhoades, RB1
Wittig, HJ1
Haugh, LD1
Mattioli, R1
Tesi, A1
Jackson, RH1
Garrido, R1
Lynes, TE1
Wood, SF1
Kaiser, HB1
Gellhaus, M1
Donnelly, A2
Boner, AL1
Miglioranzi, P1
Richelli, C1
Marchesi, E1
Andreoli, A1
von Maur, K1
Albertini, G1
Davalli, R1
Moroni, P1
Oberhauser, V1
Sooknundun, M1
Kacker, SK1
Sundaram, KR1
Johansen, LV1
Bjerrum, P1
Illum, P1
Pastorello, EA1
Ortolani, C1
Gerosa, S1
Pravettoni, V1
Codecasa, LR1
Fugazza, A1
Zanussi, C1
Fireman, P1
Skoner, D1
Tanner, E1
Doyle, W1
Backhouse, CI1
Rosenberg, R1
Campbell, BH1
Connell, JT1
Diamond, L1
Hamilton, LH1
Rosenthal, RR1
Hemsworth, GR1
Perhach, JL1
van Niekerk, CH1
Gutkowski, A1
Del Carpio, J1
Gelinas, B1
Schulz, J1
Turenne, Y1
Buckley, CE1
Klemawesch, SJ1
Lucas, SK1
Heron, TG1
Hinkelmann, B1
Seebohm, PM1
Hyde, JS1
Floro, LD1
Gomez del Intento, E1
Alberto Rossi, E1
Ruiz Moreno, G1
Ashe, GJ1
Jarvis, JF1
Lange, HJ1
Gomez, J1
Gomez, G1
Hosen, H1
Hutchinson, GW1
Griffiths, RW1
Taylor, G1
Shivalkar, PR1
Maddison, B1
Clements, RD1
Rivett, GC1
Roberts, RR1
Holland, EJ1
Douse, FA1
Miller, J1
Filipp, G1
McGuinness, BW1
Parkin, JB1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prescription Methods Assessment Project (PMAP)[NCT00393653]800 participants (Anticipated)Interventional2006-10-31Terminated (stopped due to Funding ended early)
Phase III Study Comparing Coristina® D to Resfenol® in the Symptomatic Treatment of Common Cold[NCT02735070]Phase 3366 participants (Anticipated)Interventional2016-09-30Not yet recruiting
Nasal Ocular Reflexes Contribute to Eye Symptoms in Patients With Allergic Rhinitis[NCT00117832]20 participants Interventional2005-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for chlorpheniramine and Hay Fever

ArticleYear
Clinical experience with non-sedating antihistamines in paediatric allergic rhinitis.
    Rhinology. Supplement, 1992, Volume: 13

    Topics: Adolescent; Astemizole; Asthma; Child; Child, Preschool; Chlorpheniramine; Clinical Trials as Topic;

1992
H1-receptor antagonist treatment of seasonal allergic rhinitis.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:6 Pt 2

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Clemastine; Cyprohep

1990

Trials

54 trials available for chlorpheniramine and Hay Fever

ArticleYear
Single-patient drug trial methodology for allergic rhinitis.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:9

    Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Child; Chlorpheniramine; Clinical Trials as Topic; Da

2002
Addition of ibuprofen to pseudoephedrine and chlorpheniramine in the treatment of seasonal allergic rhinitis.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2004, Volume: 93, Issue:5

    Topics: Adult; Chlorpheniramine; Double-Blind Method; Drug Therapy, Combination; Ephedrine; Female; Humans;

2004
[A clinical trial to evaluate the efficacy and safety of compound pseudoephedrine hydrochloride sustained release capsule in patients with seasonal allergic rhinitis].
    Zhonghua er bi yan hou ke za zhi, 2004, Volume: 39, Issue:9

    Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Capsules; Chlorpheniramine; Delayed-Action Preparatio

2004
A double blind trial of terfenadine and placebo in hay fever using a substitution technique for non-responders.
    The Journal of international medical research, 1980, Volume: 8, Issue:6

    Topics: Adult; Benzhydryl Compounds; Chlorpheniramine; Double-Blind Method; Female; Histamine H1 Antagonists

1980
Clinical studies with terfenadine in seasonal allergic rhinitis in France.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:9a

    Topics: Adolescent; Adult; Aged; Benzhydryl Compounds; Child; Chlorpheniramine; Circadian Rhythm; Female; Fr

1982
Summary of four UK clinical trials with terfenadine.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:9a

    Topics: Benzhydryl Compounds; Chlorpheniramine; Histamine H1 Antagonists; Humans; Rhinitis, Allergic, Perenn

1982
Evaluation of combined H1- and H2-receptor blocking agents in the treatment of seasonal allergic rhinitis.
    The Journal of allergy and clinical immunology, 1983, Volume: 71, Issue:4

    Topics: Adolescent; Adult; Chlorpheniramine; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Fema

1983
Blind study of basophilic cells in nasal smears from patients with grass pollen hay fever.
    European journal of respiratory diseases. Supplement, 1983, Volume: 128 (Pt 2)

    Topics: Adolescent; Adult; Antazoline; Basophils; Chlorpheniramine; Clinical Trials as Topic; Drug Combinati

1983
A comparative study of dexchlorpheniramine maleate sustained release tablets and budesonide nasal spray in seasonal allergic rhinitis.
    Allergy, 1983, Volume: 38, Issue:7

    Topics: Administration, Intranasal; Adolescent; Adult; Aerosols; Anti-Inflammatory Agents; Budesonide; Chlor

1983
Ketotifen in hay fever and allergic rhinitis.
    The Practitioner, 1984, Volume: 228, Issue:1393

    Topics: Adolescent; Adult; Aged; Chlorpheniramine; Clinical Trials as Topic; Double-Blind Method; Female; Hu

1984
An antihistamine-sympathomimetic combination in the treatment of hayfever. A report fom the General Practitioner Research Group.
    The Practitioner, 1981, Volume: 225, Issue:1356

    Topics: Adult; Chlorpheniramine; Clinical Trials as Topic; Delayed-Action Preparations; Drug Combinations; E

1981
A new approach to the treatment of seasonal allergic rhinitis.
    The British journal of clinical practice, 1982, Volume: 36, Issue:9

    Topics: Adolescent; Adult; Chlorpheniramine; Female; Humans; Ketotifen; Male; Middle Aged; Rhinitis, Allergi

1982
Effects of oxatomide compared with chlorpheniramine in allergic rhinoconjunctivitis.
    Clinical allergy, 1981, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Chlorpheniramine; Conjunctivitis; Humans; Middle Aged; Piperazines; Pollen; Rhini

1981
Performance in students with seasonal allergy.
    The Journal of international medical research, 1980, Volume: 8, Issue:3

    Topics: Adult; Chlorpheniramine; Female; Humans; Male; Methylprednisolone; Rhinitis, Allergic, Seasonal; Sle

1980
A dose-ranging study of the efficacy and safety of azelastine nasal spray in the treatment of seasonal allergic rhinitis with an acute model.
    The Journal of allergy and clinical immunology, 1994, Volume: 94, Issue:6 Pt 1

    Topics: Administration, Intranasal; Adolescent; Adult; Aged; Child; Chlorpheniramine; Dose-Response Relation

1994
Comparison of CNS adverse effects between astemizole and chlorpheniramine in children: a randomized, double-blind study.
    Developmental pharmacology and therapeutics, 1993, Volume: 20, Issue:3-4

    Topics: Adolescent; Astemizole; Attention; Behavior; Central Nervous System; Child; Chlorpheniramine; Cross-

1993
A double-blind, placebo-controlled trial by the sublingual route of immunotherapy with a standardized grass pollen extract.
    Allergy, 1994, Volume: 49, Issue:5

    Topics: Administration, Sublingual; Adolescent; Adult; Aerosols; Betamethasone; Chlorpheniramine; Combined M

1994
[Sublingual specific immunotherapy for rhinoconjunctivitis caused by grass pollens].
    Allergie et immunologie, 1993, Volume: 25, Issue:6

    Topics: Administration, Sublingual; Adolescent; Adult; Allergens; Betamethasone; Chlorpheniramine; Combined

1993
Model for outcomes assessment of antihistamine use for seasonal allergic rhinitis.
    The Journal of allergy and clinical immunology, 1996, Volume: 97, Issue:6

    Topics: Adolescent; Adult; Cetirizine; Chlorpheniramine; Decision Making; Female; Formularies as Topic; Hist

1996
Double-strength beclomethasone dipropionate (84 micrograms/spray) aqueous nasal spray in the treatment of seasonal allergic rhinitis.
    The Journal of allergy and clinical immunology, 1996, Volume: 98, Issue:2

    Topics: Administration, Intranasal; Adolescent; Adult; Aged; Beclomethasone; Child; Chlorpheniramine; Dose-R

1996
A corticosteroid nasal spray in hayfever.
    Current therapeutic research, clinical and experimental, 1976, Volume: 19, Issue:6

    Topics: Administration, Intranasal; Adolescent; Adult; Aerosols; Beclomethasone; Child; Chlorpheniramine; Cl

1976
Double-blind comparison of two antihistamines: mequitazine and dexchlorpheniramine.
    Current medical research and opinion, 1978, Volume: 5, Issue:5

    Topics: Chlorpheniramine; Clinical Trials as Topic; Double-Blind Method; Female; Histamine H1 Antagonists; H

1978
[Comparative trial of 2 antihistaminics: mequitazine and dexchlorpheniramine].
    Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris, 1978, Volume: 95, Issue:6

    Topics: Adult; Chlorpheniramine; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method;

1978
Physiologic/clinical comparisons of a sustained-release decongestant combination, its components and placebo in patients with allergic rhinitis.
    The Journal of asthma research, 1975, Volume: 13, Issue:1

    Topics: Airway Resistance; Belladonna Alkaloids; Chlorpheniramine; Chronic Disease; Clinical Trials as Topic

1975
Double-blind trials of clemastine ('Tavegil') in allergic rhinitis.
    Current medical research and opinion, 1975, Volume: 3, Issue:3

    Topics: Adolescent; Adult; Child; Child, Preschool; Chlorpheniramine; Clinical Trials as Topic; Drug Evaluat

1975
Oral facial dyskinesia associated with prolonged use of antihistaminic decongestants.
    The New England journal of medicine, 1975, 09-04, Volume: 293, Issue:10

    Topics: Aged; Brompheniramine; Chlorpheniramine; Face; Facial Muscles; Female; Histamine H1 Antagonists; Hum

1975
Double-blind, controlled study of clemastine fumarate, chlorpheniramine and placebo in patients with seasonal allergic rhinitis.
    Annals of allergy, 1977, Volume: 38, Issue:3

    Topics: Airway Resistance; Chlorpheniramine; Clemastine; Clinical Trials as Topic; Drug Evaluation; Humans;

1977
Double-blind, controlled study of clemastine fumarate, chlorpheniramine and placebo in the symptomatic treatment of seasonal allergic rhinitis in desensitized and nondesensitized patients.
    Annals of allergy, 1977, Volume: 38, Issue:3

    Topics: Airway Resistance; Chlorpheniramine; Clemastine; Clinical Trials as Topic; Desensitization, Immunolo

1977
Controlled trials with four per cent cromolyn spray in seasonal allergic rhinitis.
    Clinical allergy, 1977, Volume: 7, Issue:5

    Topics: Adolescent; Adult; Child; Chlorpheniramine; Clinical Trials as Topic; Cromolyn Sodium; Double-Blind

1977
A comparative study of clemastine ('Tavegil') and chlorpheniramine maleate in the treatment of hay fever.
    Current medical research and opinion, 1976, Volume: 4, Issue:4

    Topics: Adolescent; Adult; Child; Chlorpheniramine; Clemastine; Clinical Trials as Topic; Female; Humans; Ma

1976
A clinical study of the prophylactic use of betamethasone valerate and sodium cromoglycate in the treatment of seasonal allergic rhinitis.
    The Journal of laryngology and otology, 1976, Volume: 90, Issue:2

    Topics: Aerosols; Betamethasone; Betamethasone Valerate; Chlorpheniramine; Clinical Trials as Topic; Cromoly

1976
Treatment of perennial allergic rhinitis with cromolyn sodium. Double-blind study on 34 adult patients.
    The Journal of allergy and clinical immunology, 1976, Volume: 58, Issue:1 PT. 2

    Topics: Adolescent; Adult; Chlorpheniramine; Clinical Trials as Topic; Cromolyn Sodium; Female; Humans; Immu

1976
Ru-Tuss in the symptomatic treatment of allergic rhinitis.
    Annals of allergy, 1975, Volume: 35, Issue:3

    Topics: Atropine; Chlorpheniramine; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Hu

1975
Randomized, double-blind, parallel groups, placebo-controlled study of efficacy and safety of Rynatan in the treatment of allergic rhinitis using an acute model.
    Annals of allergy, 1990, Volume: 64, Issue:1

    Topics: Adolescent; Adult; Aged; Aminopyridines; Chlorpheniramine; Double-Blind Method; Drug Combinations; H

1990
Efficacy and safety of loratadine suspension in the treatment of children with allergic rhinitis.
    Allergy, 1989, Volume: 44, Issue:6

    Topics: Administration, Oral; Child; Child, Preschool; Chlorpheniramine; Cyproheptadine; Double-Blind Method

1989
Antihistamine selection in patients with allergic rhinitis.
    Annals of allergy, 1985, Volume: 55, Issue:3

    Topics: Chlorpheniramine; Clinical Trials as Topic; Diphenhydramine; Histamine H1 Antagonists; Humans; Hydro

1985
Clinical pharmacology of tritoqualine: a comparative study against dexchlorpheniramine in allergic rhinitis.
    International journal of clinical pharmacology research, 1986, Volume: 6, Issue:2

    Topics: Adolescent; Adult; Child; Chlorpheniramine; Clinical Trials as Topic; Female; Histamine H1 Antagonis

1986
Treatment of seasonal allergic rhinitis--a double blind, group comparative study of terfenadine and dexchlorpheniramine.
    Rhinology, 1987, Volume: 25, Issue:1

    Topics: Adolescent; Adult; Benzhydryl Compounds; Chlorpheniramine; Clinical Trials as Topic; Double-Blind Me

1987
Antihistaminic treatment of allergic rhinitis: a double-blind study with terfenadine versus dexchlorpheniramine.
    Pharmatherapeutica, 1987, Volume: 5, Issue:2

    Topics: Adolescent; Adult; Benzhydryl Compounds; Chlorpheniramine; Clinical Trials as Topic; Double-Blind Me

1987
Prophylaxis of whole season hay fever symptomatology: a comparison of terfenadine with chlorpheniramine.
    The British journal of clinical practice, 1987, Volume: 41, Issue:11

    Topics: Adolescent; Adult; Aged; Benzhydryl Compounds; Chlorpheniramine; Clinical Trials as Topic; Double-Bl

1987
Multicenter, double-blind, multiple-dose, parallel-groups efficacy and safety trial of azelastine, chlorpheniramine, and placebo in the treatment of spring allergic rhinitis.
    The Journal of allergy and clinical immunology, 1988, Volume: 82, Issue:5 Pt 1

    Topics: Adolescent; Adult; Chlorpheniramine; Circadian Rhythm; Clinical Trials as Topic; Dizziness; Double-B

1988
Sodium cromoglycate/chlorpheniramine and sodium cromoglycate nasal sprays in the treatment of seasonal rhinitis.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1985, May-17, Volume: 67, Issue:20

    Topics: Administration, Intranasal; Adolescent; Adult; Aerosols; Child; Chlorpheniramine; Clinical Trials as

1985
Comparative study of the efficacy, tolerance and side-effects of dexchlorpheniramine maleate 6 mg b.i.d. with terfenadine 60 mg b.i.d.
    The Journal of international medical research, 1985, Volume: 13, Issue:5

    Topics: Adolescent; Adult; Benzhydryl Compounds; Child; Chlorpheniramine; Clinical Trials as Topic; Drug Tol

1985
Treatment of allergic rhinitis with a new selective H1 antihistamine: terfenadine.
    New England and regional allergy proceedings, 1985,Winter, Volume: 6, Issue:1

    Topics: Administration, Oral; Adult; Benzhydryl Compounds; Chlorpheniramine; Clinical Trials as Topic; Doubl

1985
Double-blind cross-over study of Demazin Chronosules capsules and Eskornade spansules.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1972, May-06, Volume: 46, Issue:19

    Topics: Adolescent; Adult; Aged; Chlorpheniramine; Clinical Trials as Topic; Drug Combinations; Ephedrine; F

1972
Theophylline and chlorpheniramine in childhood asthma. Dose requirements for children 6 to 12 years (therapeutic orphans) and young adults 13 to 18 years of age receiving cromolyn sodium prophylaxis.
    Annals of allergy, 1974, Volume: 32, Issue:2

    Topics: Adolescent; Age Factors; Asthma; Bronchodilator Agents; Child; Chlorpheniramine; Clinical Trials as

1974
Oral medications in nasal decongestion. A study among industrial workers.
    IMS, Industrial medicine and surgery, 1968, Volume: 37, Issue:3

    Topics: Brompheniramine; Chlorpheniramine; Clinical Trials as Topic; Delayed-Action Preparations; Ephedrine;

1968
[Therapeutic comparison of a new antihistaminic against hay fever and an established drug].
    Arzneimittel-Forschung, 1965, Volume: 15, Issue:12

    Topics: Chlorpheniramine; Clinical Trials as Topic; Histamine H1 Antagonists; Humans; Ketones; Quinazolines;

1965
Hay fever and allergy in general practice: two antihistamine drugs compared.
    The British journal of clinical practice, 1967, Volume: 21, Issue:8

    Topics: Adolescent; Adult; Child; Chlorpheniramine; Female; Histamine H1 Antagonists; Humans; Hypersensitivi

1967
An investigation of the possible disadvantages of antihistamines in allergic asthma.
    Annals of allergy, 1972, Volume: 30, Issue:2

    Topics: Adolescent; Adult; Asthma; Child; Chlorpheniramine; Clinical Trials as Topic; Female; Histamine H1 A

1972
Meclastine in hay fever.
    The Practitioner, 1972, Volume: 208, Issue:248

    Topics: Adolescent; Adult; Aged; Benzene Derivatives; Chlorpheniramine; Clinical Trials as Topic; Ethers; Fe

1972
Local nasal desensitization in allergic rhinitis.
    Clinical allergy, 1972, Volume: 2, Issue:2

    Topics: Adolescent; Adult; Chlorpheniramine; Clinical Trials as Topic; Cromolyn Sodium; Desensitization, Imm

1972
A comparative study of two long-acting antihistamines.
    The Journal of the Royal College of General Practitioners, 1970, Volume: 19, Issue:95

    Topics: Adult; Chlorpheniramine; Clinical Trials as Topic; Female; Humans; Male; Pheniramine; Rhinitis, Alle

1970
A double-blind study of d-isoephedrine combined with chlorpheniramine in symptomatic relief of hay fever.
    Medical times, 1967, Volume: 95, Issue:3

    Topics: Chlorpheniramine; Clinical Trials as Topic; Ephedrine; Humans; Rhinitis, Allergic, Seasonal

1967

Other Studies

35 other studies available for chlorpheniramine and Hay Fever

ArticleYear
Analysis of disease-dependent sedative profiles of H(1)-antihistamines by large-scale surveillance using the visual analog scale.
    Methods and findings in experimental and clinical pharmacology, 2008, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Butyrophenones; Cetirizine; Child; Chlorpheniram

2008
Effect of histamine H1 receptor antagonists on TARC/CCL17 and MDC/CCL22 production from CD14+ cells induced by antigenic stimulation in vitro.
    International archives of allergy and immunology, 2011, Volume: 155, Issue:1

    Topics: Adult; Antigens, Plant; Cell Proliferation; Chemokine CCL17; Chemokine CCL22; Chlorpheniramine; Extr

2011
Panic disorder treated with the antihistamine chlorpheniramine.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2003, Volume: 90, Issue:3

    Topics: Aged; Chlorpheniramine; Female; Histamine H1 Antagonists; Humans; Panic Disorder; Rhinitis, Allergic

2003
Clinical evaluation of sustained-release antihistamine (chlorprophenpyridamine) in hay fever.
    The Journal of allergy, 1954, Volume: 25, Issue:4

    Topics: Anti-Allergic Agents; Chlorpheniramine; Delayed-Action Preparations; Histamine H1 Antagonists; Hyper

1954
[Use of chlorprophenpyridamine maleate in hay fever patients under specific treatment].
    Prensa medica argentina, 1955, May-20, Volume: 42, Issue:20

    Topics: Anti-Allergic Agents; Chlorpheniramine; Histamine H1 Antagonists; Hyperthermia, Induced; Maleates; R

1955
Continuing clinical study of local treatment of allergic rhinitis; use of a nasal spray containing prednisolone acetate and chlorprophenpyridamine gluconate.
    The Annals of otology, rhinology, and laryngology, 1957, Volume: 66, Issue:3

    Topics: Biomedical Research; Chlorpheniramine; Gluconates; Histamine H1 Antagonists; Humans; Hyperthermia, I

1957
Evaluation of a long-acting oral antihistaminic decongestant (rynatan) for nasal allergies.
    Acta medica Italica di medicina tropicale e subtropicale e di gastroenterologia, 1961, Volume: 16

    Topics: Chlorpheniramine; Drug Combinations; Histamine H1 Antagonists; Humans; Nasal Decongestants; Phenylep

1961
Comparison of an antiserotonin (cyproheptadine) and a pure antihistamine chlorpheniramine in hay fever.
    Acta allergologica, 1962, Volume: 17

    Topics: Anti-Allergic Agents; Chlorpheniramine; Cyproheptadine; Histamine H1 Antagonists; Humans; Rhinitis,

1962
AN EVALUATION OF THE EFFICIENCY OF ANTI-HISTAMINES FOR THE TREATMENT OF HAY-FEVER.
    International archives of allergy and applied immunology, 1963, Volume: 23

    Topics: Anti-Allergic Agents; Chlorpheniramine; Histamine; Histamine H1 Antagonists; Humans; Lactose; Promet

1963
THE USE OF DEXCHLORPHENIRAMINE TO TREAT NASAL ALLERGIES.
    Current therapeutic research, clinical and experimental, 1964, Volume: 6

    Topics: Child; Chlorpheniramine; Drug Therapy; Geriatrics; Humans; Rhinitis; Rhinitis, Allergic, Seasonal

1964
Evaluation of chlor-trimeton maleate in hay fever and a variety of allergic diseases.
    The New England journal of medicine, 1950, Jun-15, Volume: 242, Issue:24

    Topics: Anaphylaxis; Chlorpheniramine; Histamine; Humans; Hypersensitivity; Maleates; Rhinitis, Allergic, Se

1950
Effects of mometasone furoate on a rat allergic rhinitis model.
    European journal of pharmacology, 2005, Nov-07, Volume: 524, Issue:1-3

    Topics: Administration, Intranasal; Animals; Anti-Allergic Agents; Antigens; Behavior, Animal; Chlorpheniram

2005
Involvement of chemical mediators in nasal allergic responses of HDC-KO mice.
    European journal of pharmacology, 2007, Jul-19, Volume: 567, Issue:3

    Topics: Animals; Behavior, Animal; Chlorpheniramine; Histamine H1 Antagonists; Histidine Decarboxylase; Hyda

2007
Effect of antihistamine on pulmonary function of children with asthma.
    The Journal of pediatrics, 1982, Volume: 101, Issue:3

    Topics: Adolescent; Adult; Asthma; Child; Chlorpheniramine; Double-Blind Method; Female; Histamine H1 Antago

1982
[Antihistaminics and eosinophils].
    Alergia, 1982, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Chlorpheniramine; Eosinophils; Female; Histamine H1 Antagonists; Humans; Leukocyt

1982
Pharmacokinetics and efficacy of chlorpheniramine in children.
    The Journal of allergy and clinical immunology, 1982, Volume: 69, Issue:4

    Topics: Adolescent; Child; Chlorpheniramine; Female; Humans; Kinetics; Male; Rhinitis, Allergic, Seasonal

1982
Haymine--another drug combination for hay fever.
    Drug and therapeutics bulletin, 1982, May-14, Volume: 20, Issue:10

    Topics: Chlorpheniramine; Delayed-Action Preparations; Drug Combinations; Ephedrine; Humans; Rhinitis, Aller

1982
Proconvulsant effect of ketotifen, a histamine H1 antagonist, confirmed by the use of d-chlorpheniramine with monitoring electroencephalography.
    Methods and findings in experimental and clinical pharmacology, 1993, Volume: 15, Issue:3

    Topics: Child, Preschool; Chlorpheniramine; Dopamine; Electroencephalography; Epilepsies, Partial; Epinephri

1993
The effect of oral drugs on the cytologic picture of nasal mucosa in hay fever.
    Allergy, 1993, Volume: 48, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Chlorpheniramine; Drug Combinations; Ephedrine; Female; Hum

1993
Newer antihistamines.
    The Medical letter on drugs and therapeutics, 2001, Apr-30, Volume: 43, Issue:1103

    Topics: Administration, Oral; Anti-Allergic Agents; Cetirizine; Chlorpheniramine; Conscious Sedation; Diphen

2001
Letter: Dyskinesia associated with chronic antihistamine use.
    The New England journal of medicine, 1976, Jan-08, Volume: 294, Issue:2

    Topics: Chlorpheniramine; Dopamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Movement Disorders;

1976
[Action of a new drug in some acute rhinopathies and their allergic basis].
    Annali di laringologia, otologia, rinologia, faringologia, 1976, Volume: 75, Issue:1-2

    Topics: Adult; Chlorpheniramine; Cromolyn Sodium; Drug Combinations; Female; Humans; Male; Middle Aged; Rhin

1976
[Clinical study of a product combining a corticoid and antihistaminic drug].
    La Clinica terapeutica, 1977, Jul-15, Volume: 82, Issue:1

    Topics: Adolescent; Adult; Asthma; Betamethasone; Child; Chlorpheniramine; Drug Combinations; Drug Evaluatio

1977
Treatment of allergic rhinitis with a new long-acting H1 receptor antagonist: astemizole.
    Annals of allergy, 1987, Volume: 58, Issue:1

    Topics: Adult; Appetite; Astemizole; Benzimidazoles; Chlorpheniramine; Drug Evaluation; Female; Histamine H1

1987
A primate model for the evaluation of antihistamines.
    Annals of allergy, 1987, Volume: 59, Issue:6 Pt 2

    Topics: Administration, Oral; Airway Resistance; Animals; Bronchial Provocation Tests; Cetirizine; Chlorphen

1987
The use of antihistamines for the treatment of airway disease.
    Cutis, 1988, Oct-27, Volume: 42, Issue:4A

    Topics: Astemizole; Asthma; Benzhydryl Compounds; Benzimidazoles; Child; Chlorpheniramine; Double-Blind Meth

1988
[Treatment of acute nonspecific rhinitis. Studies on the long-term effect of Cimporhin].
    Fortschritte der Medizin, 1972, Sep-21, Volume: 90, Issue:26

    Topics: Acute Disease; Analgesics; Anti-Inflammatory Agents; Bronchitis; Chlorpheniramine; Drug Combinations

1972
Management of respiratory allergy by nonallergists. 1. Allergic rhinitis.
    Postgraduate medicine, 1973, Volume: 53, Issue:3

    Topics: Aerosols; Air Conditioning; Chlorpheniramine; Desensitization, Immunologic; Dexamethasone; Drug Comb

1973
[Effect of an oraly used product on allergic rhinitis].
    Prensa medica argentina, 1968, Aug-16, Volume: 55, Issue:25

    Topics: Adolescent; Caffeine; Child; Child, Preschool; Chlorpheniramine; Ephedrine; Female; Humans; Male; Na

1968
The nasal drop addict.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1969, Apr-19, Volume: 43, Issue:16

    Topics: Cautery; Chlorpheniramine; Dextroamphetamine; Humans; Methylprednisolone; Nasal Decongestants; Rhini

1969
A phenothiazine with antihistaminic properties.
    The Practitioner, 1967, Volume: 198, Issue:187

    Topics: Adolescent; Adult; Aged; Chlorpheniramine; Female; Histamine H1 Antagonists; Humans; Male; Middle Ag

1967
The use of provocative skin tests and provocative nasal tests to predetermine therapeutic results in treatment of ragweed pollinosis.
    Southern medical journal, 1971, Volume: 64, Issue:10

    Topics: Chlorpheniramine; Emulsions; Epinephrine; Histamine H1 Antagonists; Humans; Injections, Intradermal;

1971
Delayed hypersensitivity and allergic rhinitis. A negative study.
    The Journal of allergy and clinical immunology, 1972, Volume: 49, Issue:5

    Topics: Adult; Chlorpheniramine; Histamine H1 Antagonists; Humans; Hypersensitivity, Delayed; Plant Extracts

1972
[Therapy of allergic rhinopathies. Experiences with dextrochlorheniramine].
    Die Medizinische Welt, 1970, Sep-19, Volume: 38

    Topics: Chlorpheniramine; Humans; Rhinitis, Allergic, Seasonal

1970
A new long-acting formulation of chlorpheniramine maleate in hay fever.
    The British journal of clinical practice, 1971, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Aged; Child; Chlorpheniramine; Delayed-Action Preparations; Female; Humans; Male;

1971