Page last updated: 2024-10-24

chlorpheniramine and Drug Overdose

chlorpheniramine has been researched along with Drug Overdose in 16 studies

Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.

Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.

Research Excerpts

ExcerptRelevanceReference
"An 18-year-old male developed a severe serotonin syndrome after recreational ingestion of Coricidin HBP (chlorpheniramine 4 mg and dextromethorphan hydrobromide 30 mg)."7.74Serotonin syndrome in dextromethorphan ingestion responsive to propofol therapy. ( Babu, KM; Boyer, EW; Ganetsky, M, 2007)
"An 18-year-old male developed a severe serotonin syndrome after recreational ingestion of Coricidin HBP (chlorpheniramine 4 mg and dextromethorphan hydrobromide 30 mg)."3.74Serotonin syndrome in dextromethorphan ingestion responsive to propofol therapy. ( Babu, KM; Boyer, EW; Ganetsky, M, 2007)
"Accidental drug overdose is a common problem in young children."1.48Overdose in young children treated with anti-reflux medications: Poisons enquiry evidence of excess 10-fold dosing errors with ranitidine. ( Anderson, M; Bateman, DN; Cooper, G; Crawford, C; Eddleston, M; Jackson, G; Thomas, S; Thompson, J; Vale, A, 2018)
" Valproic acid elimination half-life was 3 h during the 190 min hemoperfusion cycle."1.29Delayed peak serum valproic acid in massive divalproex overdose--treatment with charcoal hemoperfusion. ( Aaron, CK; Graudins, A, 1996)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (18.75)18.2507
2000's9 (56.25)29.6817
2010's3 (18.75)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Takei, S1
Kinoshita, H1
Jamal, M1
Kumihashi, M1
Yamashita, T1
Tanaka, E1
Kawahara, S1
Abe, H1
Miyatake, N1
Kimura, S1
Crawford, C1
Anderson, M1
Cooper, G1
Jackson, G1
Thompson, J1
Vale, A1
Thomas, S1
Eddleston, M1
Bateman, DN1
Suzuki, H1
Shigeta, A1
Fukunaga, T1
Dickerson, DL1
Schaepper, MA1
Peterson, MD1
Ashworth, MD1
Karamanakos, PN1
Monte, AA1
Chuang, R1
Bodmer, M1
Gruszecki, AC1
Kloda, S1
Simmons, GT1
Daly, TM1
Hardy, RW1
Robinson, CA1
Kirages, TJ1
Sulé, HP1
Mycyk, MB1
Bobo, WV1
Fulton, RB1
Osterhoudt, KC1
Ganetsky, M1
Babu, KM1
Boyer, EW1
Backlin, SA1
Barriales Villa, R1
Batalla Celorio, A1
López de la Iglesia, J1
Barriales Alvarez, V1
Iglesias Cubero, G1
Rodríguez Blanco, VM1
Cortina Llosa, A1
Graudins, A1
Aaron, CK1
Moriya, F1
Hashimoto, Y1
Baker, SD1
Borys, DJ1

Reviews

1 review available for chlorpheniramine and Drug Overdose

ArticleYear
Dextromethorphan, chlorphenamine and serotonin toxicity: case report and systematic literature review.
    British journal of clinical pharmacology, 2010, Volume: 70, Issue:6

    Topics: Antitussive Agents; Chlorpheniramine; Dextromethorphan; Drug Overdose; Humans; Male; Serotonin Agent

2010

Other Studies

15 other studies available for chlorpheniramine and Drug Overdose

ArticleYear
An autopsy case of BRON
    Legal medicine (Tokyo, Japan), 2023, Volume: 64

    Topics: Autopsy; Caffeine; Chlorpheniramine; Drug Overdose; Eating; Fluvoxamine; Humans; Male

2023
Overdose in young children treated with anti-reflux medications: Poisons enquiry evidence of excess 10-fold dosing errors with ranitidine.
    Human & experimental toxicology, 2018, Volume: 37, Issue:4

    Topics: Age Factors; Child, Preschool; Chlorpheniramine; Databases, Factual; Domperidone; Drug Compounding;

2018
Accidental death of elderly persons under the influence of chlorpheniramine.
    Legal medicine (Tokyo, Japan), 2013, Volume: 15, Issue:5

    Topics: Accidental Falls; Aged; Autopsy; Cause of Death; Chlorpheniramine; Drowning; Drug Overdose; Drug-Rel

2013
Coricidin HBP abuse: patient characteristics and psychiatric manifestations as recorded in an inpatient psychiatric unit.
    Journal of addictive diseases, 2008, Volume: 27, Issue:1

    Topics: Acetaminophen; Adolescent; Age Factors; Alcoholism; California; Child; Chlorpheniramine; Comorbidity

2008
Intoxication with over-the-counter antitussive medication containing dihydrocodeine and chlorpheniramine causes generalized convulsion and mixed acidosis.
    Internal medicine (Tokyo, Japan), 2008, Volume: 47, Issue:20

    Topics: Acidosis; Adult; Animals; Antitussive Agents; Chlorpheniramine; Codeine; Dose-Response Relationship,

2008
Polydrug fatality involving metaxalone.
    Journal of forensic sciences, 2003, Volume: 48, Issue:2

    Topics: Adult; Chlorpheniramine; Citalopram; Drug Overdose; Ethanol; Fatal Outcome; Female; Forensic Medicin

2003
Severe manifestations of coricidin intoxication.
    The American journal of emergency medicine, 2003, Volume: 21, Issue:6

    Topics: Acetaminophen; Adolescent; Antidepressive Agents; Chemical and Drug Induced Liver Injury; Chlorpheni

2003
Commentary on: Severe manifestations of coricidin intoxication.
    The American journal of emergency medicine, 2004, Volume: 22, Issue:7

    Topics: Acetaminophen; Chlorpheniramine; Dextromethorphan; Drug Combinations; Drug Overdose; Excitatory Amin

2004
A Cadillac ride to the emergency department.
    Pediatric emergency care, 2005, Volume: 21, Issue:12

    Topics: Acetaminophen; Adolescent; Chlorpheniramine; Delirium; Dextromethorphan; Drug Combinations; Drug Ove

2005
Serotonin syndrome in dextromethorphan ingestion responsive to propofol therapy.
    Pediatric emergency care, 2007, Volume: 23, Issue:11

    Topics: Acetaminophen; Adolescent; Algorithms; Chlorpheniramine; Dextromethorphan; Drug Combinations; Drug O

2007
Decongestant-induced hypertensive crisis.
    Canadian family physician Medecin de famille canadien, 1993, Volume: 39

    Topics: Adult; Charcoal; Chlorpheniramine; Drug Overdose; Drug Therapy, Combination; Emergency Medicine; Fem

1993
[Ventricular tachycardia secondary to phenylpropanolamine poisoning: apropos a case].
    Revista espanola de cardiologia, 1995, Volume: 48, Issue:11

    Topics: Adolescent; Chlorpheniramine; Delayed-Action Preparations; Drug Combinations; Drug Overdose; Electro

1995
Delayed peak serum valproic acid in massive divalproex overdose--treatment with charcoal hemoperfusion.
    Journal of toxicology. Clinical toxicology, 1996, Volume: 34, Issue:3

    Topics: Adult; Anticonvulsants; Charcoal; Chlorpheniramine; Delayed-Action Preparations; Drug Overdose; Fema

1996
Postmortem diffusion of drugs from the bladder into femoral venous blood.
    Forensic science international, 2001, Dec-01, Volume: 123, Issue:2-3

    Topics: Adolescent; Chlorpheniramine; Codeine; Diffusion; Diphenhydramine; Drowning; Drug Overdose; Femoral

2001
A possible trend suggesting increased abuse from Coricidin exposures reported to the Texas Poison Network: comparing 1998 to 1999.
    Veterinary and human toxicology, 2002, Volume: 44, Issue:3

    Topics: Acetaminophen; Adolescent; Adolescent Behavior; Age Factors; Antitussive Agents; Child; Chlorphenira

2002