chlorpheniramine has been researched along with Common Cold in 35 studies
Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.
Common Cold: A catarrhal disorder of the upper respiratory tract, which may be viral or a mixed infection. It generally involves a runny nose, nasal congestion, and sneezing.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A fixed-dose combination of paracetamol, chlorphenamine and phenylephrine was safe and more effective than placebo in the symptomatic treatment of the common cold or flu-like syndrome in adults." | 9.17 | Symptomatic treatment of the common cold with a fixed-dose combination of paracetamol, chlorphenamine and phenylephrine: a randomized, placebo-controlled trial. ( Costa, MB; da Veiga Picon, R; Dornelles, AD; Fendt, LC; Picon, PD; Saccilotto, IC; Schmidt, LF; Suksteris, ML, 2013) |
| "The present paper describes a simple, accurate and precise reversed phase HPLC method for rapid and simultaneous quantification of codeine phosphate, ephedrine HCl and chlorpheniramine maleate in a cough-cold syrup formulation." | 7.72 | A chromatographic method for rapid and simultaneous analysis of codeine phosphate, ephedrine HCl and chlorpheniramine maleate in cough-cold syrup formulation. ( Cheung, HY; Hood, DJ, 2003) |
| " Eligible participants with at least moderate common cold or flu symptoms and symptom onset ≤ 48 hours before screening were assigned to a single multiple-active-ingredient tablet (containing paracetamol, pseudoephedrine hydrochloride, dextromethorphan hydrobromide, and chlorpheniramine maleate) or placebo tablet." | 5.27 | Time-to-onset of cold and flu symptom relief: A randomized, double-blind, placebo-controlled pilot study for a multi-symptom combination product. ( Mallefet, P; Zhang, Y, 2018) |
| "A fixed-dose combination of paracetamol, chlorphenamine and phenylephrine was safe and more effective than placebo in the symptomatic treatment of the common cold or flu-like syndrome in adults." | 5.17 | Symptomatic treatment of the common cold with a fixed-dose combination of paracetamol, chlorphenamine and phenylephrine: a randomized, placebo-controlled trial. ( Costa, MB; da Veiga Picon, R; Dornelles, AD; Fendt, LC; Picon, PD; Saccilotto, IC; Schmidt, LF; Suksteris, ML, 2013) |
| "A prospective, randomized, double-blind, multicenter, 4-arm, controlled trial was carried out in 1,167 patients with common cold treated with one of the following medications: Grippostad-C, a combination of acetaminophen, caffeine, chlorpheniramine and ascorbic acid (verum), ascorbic acid (control), chlorpheniramine and ascorbic acid (reference 1), as well as acetaminophen, caffeine, and ascorbic acid (reference 2)." | 5.10 | Evaluation of the efficacy of a combined formulation (Grippostad-C) in the therapy of symptoms of common cold: a randomized, double-blind, multicenter trial. ( Alken, RG; Bacratcheva, N; Gawronska-Szklarz, B; Giesel, B; Koytchev, R; Mrozikiewiczs, A; van der Meer, M; Vlahov, V; Wojcicki, J, 2003) |
| "This paper presents the results of a randomized, double-blind, placebo-controlled study of the efficacy of chlorpheniramine in relieving the symptoms and attenuating the pathophysiologic correlates of a rhinovirus "common cold." | 5.06 | A double-blind, placebo-controlled clinical trial of the effect of chlorpheniramine on the response of the nasal airway, middle ear and eustachian tube to provocative rhinovirus challenge. ( Doyle, WJ; Gwaltney, JM; Maddern, BR; McBride, TP; Skoner, DP; Uhrin, M, 1988) |
| "A randomized, double-blind, placebo-controlled study was done on 106 volunteers to assess the effectiveness of chlorpheniramine maleate against the common cold." | 5.05 | The effectiveness of antihistamines in the common cold. ( Crutcher, JE; Kantner, TR, 1981) |
| "A multicentric trial compared the effect of chlorpheniramine maleate with a placebo on the signs and symptoms of the common cold." | 5.04 | Effectiveness of antihistamines in the symptomatic management of the common cold. ( Belman, MA; Crutcher, JE; Danzig, MR; Howard, JC; Kantner, TR; Krum, RE; Lilienfield, LS; Princiotto, JV, 1979) |
| "A combination of paracetamol, pseudoephedrine, chlorpheniramine, and sodium benzoate in (Cold-Flu) 1,2,3 Syrup dosage form is specified for the treatment of common cold and flu symptoms." | 4.12 | Stability-Indicating New RP-UPLC Method for Simultaneous Determination of a Quaternary Mixture of Paracetamol, Pseudoephedrine, Chlorpheniramine, and Sodium Benzoate in (Cold-Flu) Syrup Dosage Form. ( Mohamed, MA, 2022) |
| "Different pharmaceutical preparations against the common cold contain acetaminophen, phenylephrine hydrochloride, and chlorpheniramine maleate." | 3.73 | Major degradation product identified in several pharmaceutical formulations against the common cold. ( Al-Mamoon, S; Chan, TM; Cooper, T; Wiseman, L; Wong, J; Zhang, LK, 2006) |
| "The present paper describes a simple, accurate and precise reversed phase HPLC method for rapid and simultaneous quantification of codeine phosphate, ephedrine HCl and chlorpheniramine maleate in a cough-cold syrup formulation." | 3.72 | A chromatographic method for rapid and simultaneous analysis of codeine phosphate, ephedrine HCl and chlorpheniramine maleate in cough-cold syrup formulation. ( Cheung, HY; Hood, DJ, 2003) |
| "We studied accidental exposure to pediatric cough/cold medications in children under 6-y-of-age to determine whether the presence of an antihistamine (chlorpheniramine) in the product increased the likelihood for adverse outcomes." | 3.69 | Antihistamine-containing cough/cold medications present a low hazard in pediatric accidental exposure incidents: analysis of Poison Control Center data. ( Abeln, SB; Skare, JA, 1997) |
| " One of the sisters experienced a common cold before the pemphigus developed and displayed a positive macrophage migration inhibition (MIF) test to a combination drug compounded of paracetamol, caffeine, chlorpheniramine maleate and phenylephrine HCl, which she had received 2 weeks prior to the appearance of the cutaneous lesions." | 3.68 | A possible case of drug-induced familial pemphigus. ( Brenner, S; Dascalu, D; Hodak, E; Lurie, R; Wolf, R, 1990) |
| "Simple, accurate, and selective methods have been developed and validated for simultaneous determination of a ternary mixture of Chlorpheniramine maleate (CPM), Pseudoephedrine HCl (PSE) and Ibuprofen (IBF), in tablet dosage form." | 1.42 | Evaluating the efficiency of spectral resolution of univariate methods manipulating ratio spectra and comparing to multivariate methods: an application to ternary mixture in common cold preparation. ( Ali, O; Hegazy, M; Moustafa, AA; Salem, H, 2015) |
| "Acetaminophen was detected in blood from each of the five cases with sufficient sample." | 1.34 | Possible role of pseudoephedrine and other over-the-counter cold medications in the deaths of very young children. ( Chmara, ES; Collins, GL; Mundy, LA; Wingert, WE, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (31.43) | 18.7374 |
| 1990's | 5 (14.29) | 18.2507 |
| 2000's | 15 (42.86) | 29.6817 |
| 2010's | 3 (8.57) | 24.3611 |
| 2020's | 1 (2.86) | 2.80 |
| Authors | Studies |
|---|---|
| Mohamed, MA | 1 |
| Zhang, Y | 1 |
| Mallefet, P | 1 |
| Picon, PD | 1 |
| Costa, MB | 1 |
| da Veiga Picon, R | 1 |
| Fendt, LC | 1 |
| Suksteris, ML | 1 |
| Saccilotto, IC | 1 |
| Dornelles, AD | 1 |
| Schmidt, LF | 1 |
| Moustafa, AA | 1 |
| Salem, H | 1 |
| Hegazy, M | 1 |
| Ali, O | 1 |
| Liu, X | 2 |
| Zhang, J | 1 |
| Chen, X | 4 |
| Pourahmad, M | 1 |
| Sobhanian, S | 1 |
| Gwaltney, JM | 3 |
| Winther, B | 1 |
| Patrie, JT | 1 |
| Hendley, JO | 1 |
| Hood, DJ | 1 |
| Cheung, HY | 1 |
| Koytchev, R | 1 |
| Vlahov, V | 1 |
| Bacratcheva, N | 1 |
| Giesel, B | 1 |
| Gawronska-Szklarz, B | 1 |
| Wojcicki, J | 1 |
| Mrozikiewiczs, A | 1 |
| van der Meer, M | 1 |
| Alken, RG | 1 |
| SNYDER, AJ | 1 |
| KOVALEFF, MO | 1 |
| MANSON, MH | 1 |
| WELLS, RL | 1 |
| WHITNEY, LH | 1 |
| BABCOCK, G | 1 |
| Mao, YQ | 1 |
| Mu, ZX | 1 |
| Zhang, YF | 1 |
| Dong, Y | 1 |
| Chen, Y | 1 |
| Hu, Z | 1 |
| Wong, J | 1 |
| Wiseman, L | 1 |
| Al-Mamoon, S | 1 |
| Cooper, T | 1 |
| Zhang, LK | 1 |
| Chan, TM | 1 |
| Wingert, WE | 1 |
| Mundy, LA | 1 |
| Collins, GL | 1 |
| Chmara, ES | 1 |
| Liu, L | 1 |
| Chen, H | 1 |
| Virtanen, H | 1 |
| Crutcher, JE | 2 |
| Kantner, TR | 2 |
| Halstead, GW | 1 |
| Skare, JA | 1 |
| Abeln, SB | 1 |
| Kasamatsu, Y | 1 |
| Osada, M | 1 |
| Ashida, K | 1 |
| Azukari, K | 1 |
| Yoshioka, K | 1 |
| Ohsawa, A | 1 |
| Suntornsuk, L | 1 |
| Banerji, S | 1 |
| Anderson, IB | 1 |
| Cardona, I | 1 |
| Grau, S | 1 |
| Marín, M | 1 |
| Howard, JC | 1 |
| Lilienfield, LS | 1 |
| Princiotto, JV | 1 |
| Krum, RE | 1 |
| Belman, MA | 1 |
| Danzig, MR | 1 |
| Madsen, RE | 1 |
| Magin, DF | 1 |
| Sakchainanont, B | 1 |
| Ruangkanchanasetr, S | 1 |
| Chantarojanasiri, T | 1 |
| Tapasart, C | 1 |
| Suwanjutha, S | 1 |
| Brenner, S | 1 |
| Hodak, E | 1 |
| Dascalu, D | 1 |
| Lurie, R | 1 |
| Wolf, R | 1 |
| Nishi, H | 1 |
| Fukuyama, T | 1 |
| Matsuo, M | 1 |
| Terabe, S | 1 |
| Doyle, WJ | 1 |
| McBride, TP | 1 |
| Skoner, DP | 1 |
| Maddern, BR | 1 |
| Uhrin, M | 1 |
| Gaffey, MJ | 1 |
| Sastre, A | 1 |
| Dressler, WE | 1 |
| Sorrentino, JV | 1 |
| Hayden, FG | 1 |
| Sachsenröder, L | 1 |
| Renovanz, HD | 1 |
| Flach, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase III Study Comparing Coristina® D to Resfenol® in the Symptomatic Treatment of Common Cold[NCT02735070] | Phase 3 | 366 participants (Anticipated) | Interventional | 2016-09-30 | Not yet recruiting | ||
| Evaluation of the Efficacy and Safety of Fixed Combination of Paracetamol, Chlorpheniramine and Phenylephrine in the Treatment of Symptomatic Common Cold and Flu Syndrome in Adults[NCT01389518] | Phase 3 | 146 participants (Actual) | Interventional | 2009-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 trials available for chlorpheniramine and Common Cold
| Article | Year |
|---|---|
Time-to-onset of cold and flu symptom relief: A randomized, double-blind, placebo-controlled pilot study for a multi-symptom combination product.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Antitussive Agents; China; Chl | 2018 |
Symptomatic treatment of the common cold with a fixed-dose combination of paracetamol, chlorphenamine and phenylephrine: a randomized, placebo-controlled trial.
Topics: Acetaminophen; Adolescent; Adult; Chlorpheniramine; Common Cold; Double-Blind Method; Drug Combinati | 2013 |
Symptomatic treatment of the common cold with a fixed-dose combination of paracetamol, chlorphenamine and phenylephrine: a randomized, placebo-controlled trial.
Topics: Acetaminophen; Adolescent; Adult; Chlorpheniramine; Common Cold; Double-Blind Method; Drug Combinati | 2013 |
Symptomatic treatment of the common cold with a fixed-dose combination of paracetamol, chlorphenamine and phenylephrine: a randomized, placebo-controlled trial.
Topics: Acetaminophen; Adolescent; Adult; Chlorpheniramine; Common Cold; Double-Blind Method; Drug Combinati | 2013 |
Symptomatic treatment of the common cold with a fixed-dose combination of paracetamol, chlorphenamine and phenylephrine: a randomized, placebo-controlled trial.
Topics: Acetaminophen; Adolescent; Adult; Chlorpheniramine; Common Cold; Double-Blind Method; Drug Combinati | 2013 |
Combined antiviral-antimediator treatment for the common cold.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Chlorpheniramine; Common Cold; Cough; Do | 2002 |
Evaluation of the efficacy of a combined formulation (Grippostad-C) in the therapy of symptoms of common cold: a randomized, double-blind, multicenter trial.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Ascorbic Acid; Caffeine; Chlorphen | 2003 |
A slow release combined preparation (dexchlorpheniramine + pseudoephedrine) for symptomatic treatment of the common cold.
Topics: Adult; Chlorpheniramine; Clinical Trials as Topic; Common Cold; Delayed-Action Preparations; Double- | 1983 |
The effectiveness of antihistamines in the common cold.
Topics: Adult; Chlorpheniramine; Clinical Trials as Topic; Common Cold; Double-Blind Method; Female; Humans; | 1981 |
Effectiveness of antihistamines in the symptomatic management of the common cold.
Topics: Adolescent; Adult; Chlorpheniramine; Common Cold; Female; Humans; Informed Consent; Male | 1979 |
Effectiveness of antihistamines in common cold.
Topics: Child, Preschool; Chlorpheniramine; Clemastine; Common Cold; Double-Blind Method; Histamine H1 Antag | 1990 |
A double-blind, placebo-controlled clinical trial of the effect of chlorpheniramine on the response of the nasal airway, middle ear and eustachian tube to provocative rhinovirus challenge.
Topics: Acoustic Impedance Tests; Adult; Chlorpheniramine; Clinical Trials as Topic; Common Cold; Double-Bli | 1988 |
Intranasally and orally administered antihistamine treatment of experimental rhinovirus colds.
Topics: Administration, Intranasal; Administration, Oral; Adult; Chlorpheniramine; Clinical Trials as Topic; | 1987 |
[Efficacy and tolerance of a combined oral rhinologic agent].
Topics: Animals; Aspirin; Benzoxazoles; Biometry; Chlorpheniramine; Clinical Trials as Topic; Common Cold; D | 1972 |
24 other studies available for chlorpheniramine and Common Cold
| Article | Year |
|---|---|
Stability-Indicating New RP-UPLC Method for Simultaneous Determination of a Quaternary Mixture of Paracetamol, Pseudoephedrine, Chlorpheniramine, and Sodium Benzoate in (Cold-Flu) Syrup Dosage Form.
Topics: Acetaminophen; Chlorpheniramine; Chromatography, High Pressure Liquid; Common Cold; Humans; Pseudoep | 2022 |
Evaluating the efficiency of spectral resolution of univariate methods manipulating ratio spectra and comparing to multivariate methods: an application to ternary mixture in common cold preparation.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chlorpheniramine; Common Cold; Drug Combinations; Histamine | 2015 |
Online concentration by head-column field-amplified with large-volume sample stacking using flow injection-capillary electrophoresis for the analysis of four active components in cold medicines.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Allergic Agents; Antitussive Agents; Chlorpheniramine; | 2008 |
Effect of honey on the common cold.
Topics: Acetaminophen; Adult; Chlorpheniramine; Common Cold; Female; Honey; Humans; Male; Naproxen; Treatmen | 2009 |
Best drugs for what ails you: the brands to buy--and those to skip.
Topics: Acetaminophen; Anesthetics, Local; Cetirizine; Chlorpheniramine; Common Cold; Cough; Dextromethorpha | 2009 |
A chromatographic method for rapid and simultaneous analysis of codeine phosphate, ephedrine HCl and chlorpheniramine maleate in cough-cold syrup formulation.
Topics: Chemistry, Pharmaceutical; Chlorpheniramine; Chromatography, High Pressure Liquid; Codeine; Common C | 2003 |
HOW RELIABLY CAN INDUSTRIAL DISPENSARIES RATE THE SAME DRUG GIVEN IN DISGUISED FORMS.
Topics: Antitussive Agents; Biomedical Research; Chlorpheniramine; Common Cold; Drug Therapy; Humans; Indust | 1964 |
A study of coricidin in the treatment of the common cold.
Topics: Acetaminophen; Chlorpheniramine; Common Cold; Histamine Antagonists | 1950 |
Coricidin in the treatment of the common cold.
Topics: Acetaminophen; Chlorpheniramine; Common Cold; Histamine H1 Antagonists; Humans; Pheniramine | 1951 |
[Experimental study on the pharmacology of 999 ganmaoling, a compound recipe of Chinese and Western materia medica].
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Chlorpheniramine; Common | 2004 |
Separation and determination of pseudoephedrine, dextromethorphan, diphenhydramine and chlorpheniramine in cold medicines by nonaqueous capillary electrophoresis.
Topics: Chlorpheniramine; Common Cold; Dextromethorphan; Diphenhydramine; Electrophoresis, Capillary; Ephedr | 2005 |
Are any cold medications safe for a person on high blood pressure medication?
Topics: Acetaminophen; Chlorpheniramine; Common Cold; Dextromethorphan; Drug Combinations; Drug Interactions | 2006 |
Major degradation product identified in several pharmaceutical formulations against the common cold.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Allergic Agents; Chemistry, Pharmaceutical; Chlorpheni | 2006 |
Possible role of pseudoephedrine and other over-the-counter cold medications in the deaths of very young children.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Antitussive Agents; Brompheniramine; Bronchodil | 2007 |
Separation and determination of four active components in medicinal preparations by flow injection-capillary electrophoresis.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Antitussive Agents; Bronchodilator Agents; Buffers; Chlorph | 2007 |
Determination of amine ingredients in cough-cold liquids by reversed-phase ion-pair high-performance liquid chromatography.
Topics: Amines; Chlorpheniramine; Chromatography, High Pressure Liquid; Common Cold; Dextromethorphan; Hydro | 1982 |
Antihistamine-containing cough/cold medications present a low hazard in pediatric accidental exposure incidents: analysis of Poison Control Center data.
Topics: Child; Child, Preschool; Chlorpheniramine; Common Cold; Cough; Histamine H1 Antagonists; Humans; Inf | 1997 |
Rhabdomyolysis after infection and taking a cold medicine in a patient who was susceptible to malignant hyperthermia.
Topics: Adult; Caffeine; Chlorpheniramine; Common Cold; Dantrolene; Halothane; Humans; In Vitro Techniques; | 1998 |
Separation of cold medicine ingredients by capillary electrophoresis.
Topics: Acetaminophen; Buffers; Chlorpheniramine; Chromatography, Micellar Electrokinetic Capillary; Common | 2001 |
Abuse of Coricidin HBP cough & cold tablets: episodes recorded by a poison center.
Topics: Adolescent; Adult; Antitussive Agents; California; Chlorpheniramine; Common Cold; Cough; Dextrometho | 2001 |
[Sudden death attributed to ventricular arrhytmia induced by an over-the-counter drug for influenza].
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Arrhythmias, Cardiac; Chlorpheniramine; Common Cold; | 2002 |
Simultaneous quantitative GLC determination of chlorpheniramine maleate and phenylpropanolamine hydrochloride in a cold tablet preparation.
Topics: Aspirin; Chlorpheniramine; Chromatography, Gas; Common Cold; Phenylpropanolamine; Tablets | 1976 |
A possible case of drug-induced familial pemphigus.
Topics: Acetaminophen; Caffeine; Chlorpheniramine; Common Cold; Drug Combinations; Female; Humans; Middle Ag | 1990 |
Separation and determination of the ingredients of a cold medicine by micellar electrokinetic chromatography with bile salts.
Topics: Acetaminophen; Bile Acids and Salts; Caffeine; Chlorpheniramine; Chromatography; Common Cold; Hydrog | 1990 |