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chlorpheniramine and Chemical Dependence

chlorpheniramine has been researched along with Chemical Dependence in 23 studies

Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.

Research Excerpts

ExcerptRelevanceReference
"An 18-year-old male developed a severe serotonin syndrome after recreational ingestion of Coricidin HBP (chlorpheniramine 4 mg and dextromethorphan hydrobromide 30 mg)."7.74Serotonin syndrome in dextromethorphan ingestion responsive to propofol therapy. ( Babu, KM; Boyer, EW; Ganetsky, M, 2007)
"An 18-year-old male developed a severe serotonin syndrome after recreational ingestion of Coricidin HBP (chlorpheniramine 4 mg and dextromethorphan hydrobromide 30 mg)."3.74Serotonin syndrome in dextromethorphan ingestion responsive to propofol therapy. ( Babu, KM; Boyer, EW; Ganetsky, M, 2007)
"Dextromethorphan is a nonprescription antitussive which has been gaining in popularity as an abused drug, because of the hallucinogenic, dissociative, and intoxicating effects it produces at high doses."1.35Combined dextromethorphan and chlorpheniramine intoxication in impaired drivers. ( Logan, BK, 2009)
" The potentiation of dihydrocodeine-conditioned place preference was observed by combination with chlorpheniramine (0."1.28Drug interactions in the reinforcing effects of over-the-counter cough syrups. ( Masukawa, Y; Misawa, M; Suzuki, T, 1990)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19906 (26.09)18.7374
1990's3 (13.04)18.2507
2000's13 (56.52)29.6817
2010's1 (4.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Das, S1
Palappallil, DS1
B C, M1
Chatterjee, SS1
Murao, S1
Manabe, H1
Yamashita, T1
Sekikawa, T1
Dickerson, DL1
Schaepper, MA1
Peterson, MD1
Ashworth, MD1
Logan, BK1
Kirages, TJ1
Sulé, HP1
Mycyk, MB1
Bobo, WV1
Fulton, RB1
Miller, SC1
Schwartz, RH1
Ganetsky, M1
Babu, KM1
Boyer, EW1
Tanda, G1
Kopajtic, TA1
Katz, JL1
Kitabayashi, Y1
Ueda, H1
Narumoto, J1
Kita, H1
Nakamura, K1
Tsuchida, H1
Tani, N1
Fukui, K1
Banerji, S1
Anderson, IB1
Moriya, F1
Hashimoto, Y1
Miyatake, R1
Doi, T1
Date, K1
Naitoh, T1
Suwaki, H1
Beardsley, PM1
Balster, RL1
Ishigooka, J1
Yoshida, Y1
Murasaki, M1
Suzuki, T2
Masukawa, Y1
Misawa, M2
Strauss, A1
Yoshida, E1
Yoshii, T1
Koike, Y1
Yanaura, S1
Watanabe, J1
Takahashi, M1
Kaneto, H1
Jarvis, JF1
Weissman, N1
Lowe, ML1
Beattie, JM1
Demetriou, JA1
Jones, IH1
Stevenson, J1
Jordan, A1
Connell, HM1
Hetherington, HD1
Gibney, GN1

Reviews

1 review available for chlorpheniramine and Chemical Dependence

ArticleYear
Adolescent abuse of dextromethorphan.
    Clinical pediatrics, 2005, Volume: 44, Issue:7

    Topics: Acetaminophen; Adolescent; Antitussive Agents; Chlorpheniramine; Dextromethorphan; Drug Combinations

2005

Other Studies

22 other studies available for chlorpheniramine and Chemical Dependence

ArticleYear
Chlorpheniramine dependence presenting as mania.
    Asian journal of psychiatry, 2017, Volume: 30

    Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Chlorpheniramine; Diagnosis, Differential; GABA Agent

2017
Intoxication with over-the-counter antitussive medication containing dihydrocodeine and chlorpheniramine causes generalized convulsion and mixed acidosis.
    Internal medicine (Tokyo, Japan), 2008, Volume: 47, Issue:11

    Topics: Acidosis; Adult; Antitussive Agents; Chlorpheniramine; Codeine; Ephedrine; Humans; Japan; Male; Nonp

2008
Coricidin HBP abuse: patient characteristics and psychiatric manifestations as recorded in an inpatient psychiatric unit.
    Journal of addictive diseases, 2008, Volume: 27, Issue:1

    Topics: Acetaminophen; Adolescent; Age Factors; Alcoholism; California; Child; Chlorpheniramine; Comorbidity

2008
Combined dextromethorphan and chlorpheniramine intoxication in impaired drivers.
    Journal of forensic sciences, 2009, Volume: 54, Issue:5

    Topics: Adolescent; Adult; Automobile Driving; Central Nervous System Depressants; Chlorpheniramine; Chromat

2009
Severe manifestations of coricidin intoxication.
    The American journal of emergency medicine, 2003, Volume: 21, Issue:6

    Topics: Acetaminophen; Adolescent; Antidepressive Agents; Chemical and Drug Induced Liver Injury; Chlorpheni

2003
Commentary on: Severe manifestations of coricidin intoxication.
    The American journal of emergency medicine, 2004, Volume: 22, Issue:7

    Topics: Acetaminophen; Chlorpheniramine; Dextromethorphan; Drug Combinations; Drug Overdose; Excitatory Amin

2004
Coricidin HBP cough and cold addiction.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2005, Volume: 44, Issue:6

    Topics: Acetaminophen; Adolescent; Animals; Antitussive Agents; Chlorpheniramine; Dextromethorphan; Drug Com

2005
Serotonin syndrome in dextromethorphan ingestion responsive to propofol therapy.
    Pediatric emergency care, 2007, Volume: 23, Issue:11

    Topics: Acetaminophen; Adolescent; Algorithms; Chlorpheniramine; Dextromethorphan; Drug Combinations; Drug O

2007
Cocaine-like neurochemical effects of antihistaminic medications.
    Journal of neurochemistry, 2008, Volume: 106, Issue:1

    Topics: Animals; Central Nervous System Stimulants; Chlorpheniramine; Cocaine; Diphenhydramine; Dopamine; Do

2008
[A case study of BRON (cough suppressant) tablet dependence--its social psychiatric and biological aspects].
    Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence, 2000, Volume: 35, Issue:5

    Topics: Adolescent; Antitussive Agents; Caffeine; Cerebrovascular Circulation; Chlorpheniramine; Codeine; Co

2000
Abuse of Coricidin HBP cough & cold tablets: episodes recorded by a poison center.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2001, Oct-01, Volume: 58, Issue:19

    Topics: Adolescent; Adult; Antitussive Agents; California; Chlorpheniramine; Common Cold; Cough; Dextrometho

2001
Postmortem diffusion of drugs from the bladder into femoral venous blood.
    Forensic science international, 2001, Dec-01, Volume: 123, Issue:2-3

    Topics: Adolescent; Chlorpheniramine; Codeine; Diffusion; Diphenhydramine; Drowning; Drug Overdose; Femoral

2001
[Clinical study of BRON-L syrup (cough suppressant) abuse].
    Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence, 2002, Volume: 37, Issue:1

    Topics: Adult; Antitussive Agents; Caffeine; Chlorpheniramine; Drug Combinations; Female; Humans; Male; Nonp

2002
The intravenous self-administration of antihistamines by rhesus monkeys.
    Drug and alcohol dependence, 1992, Volume: 30, Issue:2

    Topics: Animals; Benzhydryl Compounds; Chlorpheniramine; Cimetidine; Dose-Response Relationship, Drug; Hista

1992
Abuse of "BRON": a Japanese OTC cough suppressant solution containing methylephedrine, codeine, caffeine and chlorpheniramine.
    Progress in neuro-psychopharmacology & biological psychiatry, 1991, Volume: 15, Issue:4

    Topics: Adult; Antitussive Agents; Caffeine; Chlorpheniramine; Codeine; Drug Combinations; Ephedrine; Female

1991
Drug interactions in the reinforcing effects of over-the-counter cough syrups.
    Psychopharmacology, 1990, Volume: 102, Issue:4

    Topics: Animals; Antitussive Agents; Benzazepines; Chlorpheniramine; Codeine; Dose-Response Relationship, Dr

1990
Homicidal psychosis during the combined use of cocaine and an over-the-counter cold preparation.
    The Journal of clinical psychiatry, 1989, Volume: 50, Issue:4

    Topics: Adult; Aspirin; Bicarbonates; Chlorpheniramine; Citrates; Cocaine; Drug Combinations; Homicide; Huma

1989
[The effects of noscapine and chlorpheniramine on physical dependence and antitussive activity of dihydrocodeine].
    Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology, 1988, Volume: 8, Issue:2

    Topics: Animals; Antitussive Agents; Body Weight; Chlorpheniramine; Codeine; Drug Interactions; Guinea Pigs;

1988
[Studies on tolerance to and dependence on SS Bron solution-W: effect of major constituents on the action of dihydrocodeine in mice].
    Arukoru kenkyu to yakubutsu izon = Japanese journal of alcohol studies & drug dependence, 1986, Volume: 21, Issue:3

    Topics: Analgesia; Animals; Caffeine; Chlorpheniramine; Codeine; Drug Interactions; Ephedrine; Guinea Pigs;

1986
The nasal drop addict.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1969, Apr-19, Volume: 43, Issue:16

    Topics: Cautery; Chlorpheniramine; Dextroamphetamine; Humans; Methylprednisolone; Nasal Decongestants; Rhini

1969
Screening method for detection of drugs of abuse in human urine.
    Clinical chemistry, 1971, Volume: 17, Issue:9

    Topics: Alkaloids; Amphetamine; Analgesics; Barbiturates; Chlorpheniramine; Chromatography; Chromatography,

1971
Pheniramine as an hallucinogen.
    The Medical journal of Australia, 1973, Feb-24, Volume: 1, Issue:8

    Topics: Adolescent; Adult; Child; Child, Preschool; Chlorpheniramine; Female; Hallucinations; Hallucinogens;

1973