chlorpheniramine has been researched along with Blood Pressure, Low in 19 studies
Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Histamine, acting centrally as a neurotransmitter, evokes a reversal of hemorrhagic hypotension in rats due to the activation of the sympathetic and the renin-angiotensin systems as well as the release of arginine vasopressin and proopiomelanocortin-derived peptides." | 7.81 | Centrally injected histamine increases posterior hypothalamic acetylcholine release in hemorrhage-hypotensive rats. ( Altinbas, B; Jochem, J; Savci, V; Yalcin, M; Yilmaz, MS, 2015) |
| " H1- and H2-histamine antagonists or placebo were given before dosing with d-tubocurarine in a randomized double-blind fashion to four groups: group 1--placebo; group 2--cimetidine, 4 mg/kg, plus placebo; group 3--chlorpheniramine, 0." | 6.66 | Histamine antagonists and d-tubocurarine-induced hypotension in cardiac surgical patients. ( Akins, CW; D'Ambra, MN; Inada, E; Machaj, V; Moss, J; Philbin, DM; Rosow, CE, 1986) |
| "Pretreatment with chlorpheniramine (50 nmol icv), H1 receptor antagonist, inhibited the increase in MAP, PP, HR and survival rate produced by histamine, while chlorpheniramine given alone had no effect." | 5.31 | Cardiovascular effects of histamine administered intracerebroventricularly in critical haemorrhagic hypotension in rats. ( Jochem, J, 2000) |
| "Histamine, acting centrally as a neurotransmitter, evokes a reversal of hemorrhagic hypotension in rats due to the activation of the sympathetic and the renin-angiotensin systems as well as the release of arginine vasopressin and proopiomelanocortin-derived peptides." | 3.81 | Centrally injected histamine increases posterior hypothalamic acetylcholine release in hemorrhage-hypotensive rats. ( Altinbas, B; Jochem, J; Savci, V; Yalcin, M; Yilmaz, MS, 2015) |
| "52 patients with snake envenoming were randomised to receive infusion of hydrocortisone (Group A), hydrocortisone with chlorpheniramine bolus (Group B) or placebo (Group C) during the administration of antivenom." | 2.71 | Parallel infusion of hydrocortisone +/- chlorpheniramine bolus injection to prevent acute adverse reactions to antivenom for snakebites. ( Ariyasena, H; Dissanayake, WP; Gawarammana, IB; Kularatne, SA; Kumarasiri, RP; Senanayake, N, 2004) |
| " H1- and H2-histamine antagonists or placebo were given before dosing with d-tubocurarine in a randomized double-blind fashion to four groups: group 1--placebo; group 2--cimetidine, 4 mg/kg, plus placebo; group 3--chlorpheniramine, 0." | 2.66 | Histamine antagonists and d-tubocurarine-induced hypotension in cardiac surgical patients. ( Akins, CW; D'Ambra, MN; Inada, E; Machaj, V; Moss, J; Philbin, DM; Rosow, CE, 1986) |
| "Pretreatment with chlorpheniramine (50 nmol icv), H1 receptor antagonist, inhibited the increase in MAP, PP, HR and survival rate produced by histamine, while chlorpheniramine given alone had no effect." | 1.31 | Cardiovascular effects of histamine administered intracerebroventricularly in critical haemorrhagic hypotension in rats. ( Jochem, J, 2000) |
| "The hypotension was found to be refractory to intravenous fluids, dopamine, and antihistamines, but was immediately reversed by intravenous epinephrine." | 1.26 | Shock syndrome associated with mastocytosis: pharmacologic reversal of the acute episode and therapeutic prevention of recurrent attacks. ( Oates, JA; Roberts, LJ; Turk, JW, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (57.89) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 3 (15.79) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giangrande, N | 1 |
| García-Menaya, JM | 1 |
| Marcos-Fernández, M | 1 |
| Cámara-Hijón, C | 1 |
| Bobadilla-González, P | 1 |
| Altinbas, B | 1 |
| Yilmaz, MS | 1 |
| Savci, V | 1 |
| Jochem, J | 2 |
| Yalcin, M | 1 |
| Lyall, DA | 1 |
| McQueen, M | 1 |
| Ramaesh, K | 1 |
| Weir, C | 1 |
| Gawarammana, IB | 1 |
| Kularatne, SA | 1 |
| Dissanayake, WP | 1 |
| Kumarasiri, RP | 1 |
| Senanayake, N | 1 |
| Ariyasena, H | 1 |
| Brown, SG | 1 |
| Scott, HW | 1 |
| Parris, WC | 1 |
| Sandidge, PC | 1 |
| Oates, JA | 2 |
| Roberts, LJ | 2 |
| Turk, JW | 1 |
| Guo, Y | 1 |
| Hedqvist, P | 1 |
| Gustafsson, LE | 1 |
| Hishikawa, K | 1 |
| Nakaki, T | 1 |
| Suzuki, H | 1 |
| Saruta, T | 1 |
| Kato, R | 1 |
| Inada, E | 1 |
| Philbin, DM | 1 |
| Machaj, V | 1 |
| Moss, J | 1 |
| D'Ambra, MN | 1 |
| Rosow, CE | 1 |
| Akins, CW | 1 |
| Parsons, RS | 1 |
| Mohandas, K | 1 |
| Tuttle, RS | 1 |
| Peters, GA | 1 |
| Hodgson, JR | 1 |
| Donovan, RJ | 1 |
| Fregnan, GB | 1 |
| Glässer, AH | 1 |
| Smith, MJ | 1 |
| Kendall, BE | 1 |
| Tomlinson, S | 1 |
| Tabatabai, M | 1 |
| Ismaili, MH | 1 |
| Nazarian, I | 1 |
| Daneshbod, K | 1 |
| Doyle, TF | 1 |
| Turns, JE | 1 |
| Strike, TA | 1 |
| Polak, P | 1 |
| Laycob, L | 1 |
3 trials available for chlorpheniramine and Blood Pressure, Low
| Article | Year |
|---|---|
Parallel infusion of hydrocortisone +/- chlorpheniramine bolus injection to prevent acute adverse reactions to antivenom for snakebites.
Topics: Adult; Anti-Allergic Agents; Anti-Inflammatory Agents; Antivenins; Chlorpheniramine; Double-Blind Me | 2004 |
Histamine antagonists and d-tubocurarine-induced hypotension in cardiac surgical patients.
Topics: Blood Pressure; Chlorpheniramine; Cimetidine; Clinical Trials as Topic; Coronary Artery Bypass; Doub | 1986 |
The effect of histamine-receptor blockade on the hemodynamic responses to protamine.
Topics: Blood Pressure; Cardiopulmonary Bypass; Central Venous Pressure; Chlorpheniramine; Cimetidine; Coron | 1989 |
16 other studies available for chlorpheniramine and Blood Pressure, Low
| Article | Year |
|---|---|
Anaphylaxis due to macrogol in a laxative solution with a positive basophil activation test.
Topics: Aged; Anaphylaxis; Basophil Degranulation Test; Chlorpheniramine; Colonoscopy; Edema; Female; Humans | 2019 |
Centrally injected histamine increases posterior hypothalamic acetylcholine release in hemorrhage-hypotensive rats.
Topics: Acetylcholine; Animals; Blood Pressure; Chlorpheniramine; Choline; Disease Models, Animal; Dose-Resp | 2015 |
A sting in the tale: cross reaction hypersensitivity to hyaluronidase.
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Anti-Allergic Agents; Chlorpheniramine; Corneal Ulcer; | 2012 |
Parallel infusion of hydrocortisone with/without chlorpheniramine bolus injection to prevent acute adverse reactions to antivenom for snakebites.
Topics: Anaphylaxis; Anti-Inflammatory Agents; Antivenins; Bites and Stings; Chlorpheniramine; Confidence In | 2004 |
Hazards in operative management of patients with systemic mastocytosis.
Topics: Adult; Chlorpheniramine; Cimetidine; Face; Female; Histamine Release; Humans; Hypotension; Intraoper | 1983 |
Shock syndrome associated with mastocytosis: pharmacologic reversal of the acute episode and therapeutic prevention of recurrent attacks.
Topics: Aspirin; Chlorpheniramine; Cimetidine; Epinephrine; Humans; Hypotension; Infusions, Parenteral; Pros | 1982 |
Cardiovascular effects of histamine administered intracerebroventricularly in critical haemorrhagic hypotension in rats.
Topics: Animals; Blood Pressure; Blood Volume; Cardiovascular System; Chlorpheniramine; Critical Illness; He | 2000 |
Absence of mast cell involvement in active systemic anaphylaxis in rats.
Topics: Anaphylaxis; Animals; Blood Pressure; Cell Degranulation; Chlorpheniramine; Cimetidine; Dextrans; Ge | 2001 |
L-arginine-induced hypotension.
Topics: Arginine; Chlorpheniramine; Humans; Hypotension; Nitric Oxide; Vasodilation | 1991 |
Relationship between blood histamine and centrally evoked hypotensive response.
Topics: Animals; Atropine; Blood; Carotid Arteries; Cats; Chlorpheniramine; Histamine Release; Histidine; Hy | 1965 |
The effect of premedication with chlorpheniramine on reactions to methylglucamine iodipamide.
Topics: Adult; Anaphylaxis; Chlorpheniramine; Cholangiography; Drug Eruptions; Drug Hypersensitivity; Female | 1966 |
Synergistic action of an anti-5-hydroxytryptamine, anti-histamines and cortisone in experimental anaphylaxis.
Topics: Anaphylaxis; Animals; Aspirin; Body Temperature; Chlorpheniramine; Cortisone; Histamine H1 Antagonis | 1965 |
Adverse general reactions to high doses of methylglucamine-based contrast media.
Topics: Adipates; Adult; Age Factors; Alkaline Phosphatase; Amino Sugars; Calcium; Chlorpheniramine; Contras | 1974 |
Pathophysiological changes resulting from intravenous injection of ovine hydatid cyst fluid to sheep.
Topics: Animals; Antigen-Antibody Reactions; Apnea; Atropine; Bronchi; Capillaries; Chlorpheniramine; Echino | 1974 |
Effect of antihistamine on early transient incapacitation of monkeys subjected to 4000 rads of mixed gamma-neutron radiation.
Topics: Animals; Blood Pressure; Chlorpheniramine; Female; Haplorhini; Humans; Hypotension; Macaca; Male; Ma | 1971 |
Rapid tranquilization.
Topics: Adolescent; Blood Pressure Determination; Chlorpheniramine; Chlorpromazine; Humans; Hypotension; Mal | 1971 |