Page last updated: 2024-10-24

chlorpheniramine and Benign Neoplasms

chlorpheniramine has been researched along with Benign Neoplasms in 8 studies

Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.

Research Excerpts

ExcerptRelevanceReference
" In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome."4.80Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000)
" Particularly when this combined dosage is administered as outpatient chemotherapy, the doctor must prescribe diphenhydramine hydrochloride tablets, and the patient must not forget to bring them on the day in which chemotherapy is administered."2.73[Evaluation of short-time premedication with d-chlorpheniramine maleate injection for paclitaxel-induced hypersensitivity reaction]. ( Akase, T; Doi, M; Harada, T; Yamada, Y, 2008)
"Chronic hepatitis C was a frequent complication in patients treated for malignancy until the introduction of anti-HCV screening tests for blood donors."2.69Interferon treatment of chronic hepatitis C in patients cured of pediatric malignancies. ( Bortolotti, F; Brugiolo, A; Cesaro, S; Cusinato, R; Guido, M; Masiero, L; Petris, MG; Rossetti, F; Zanesco, L, 2000)
"In the clonogenic assay, anti- cancer activity of AMT was most active in cervical and uterine tumours, in colon cancer, glioblastoma, leukaemia, melanoma and pancreatic cancer."1.35AMT: preclinical pharmacology studies. ( Bruyns, E; Diergarten, K; Dorn, A; Drevs, J; Fiebig, HH; Maier, A; Niazi, F; Scheele, J, 2009)
"Retreatment with etoposide in these patients is difficult and generally alternative drugs/regimens have to be used."1.35Successful treatment with etoposide phosphate in patients with previous etoposide hypersensitivity. ( Collier, K; How, K; Savage, P; Schink, C; Seckl, M; Young, AM, 2008)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's0 (0.00)18.2507
2000's5 (62.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tukey, RH1
Strassburg, CP1
Harada, T1
Doi, M1
Yamada, Y1
Akase, T1
Niazi, F1
Drevs, J1
Diergarten, K1
Dorn, A1
Maier, A1
Fiebig, HH1
Bruyns, E1
Scheele, J1
Misumi, N1
Hiraike, M1
Nawata, F1
Hashimoto, M1
Tanigawa, K1
Takase, I1
Nabeshima, A1
Honda, S1
MODELL, J1
SCHWARTZ, S1
Collier, K1
Schink, C1
Young, AM1
How, K1
Seckl, M1
Savage, P1
Carella, G1
Cesaro, S1
Bortolotti, F1
Petris, MG1
Brugiolo, A1
Cusinato, R1
Guido, M1
Rossetti, F1
Masiero, L1
Zanesco, L1

Reviews

2 reviews available for chlorpheniramine and Benign Neoplasms

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia;

2000
[Antagonists of histamine H1 and H2 receptors: pharmacologic aspects and clinical significance].
    La Clinica terapeutica, 1984, Aug-31, Volume: 110, Issue:4

    Topics: Burimamide; Cardiovascular System; Chlorpheniramine; Cimetidine; Duodenal Ulcer; Gastric Acid; Hista

1984

Trials

2 trials available for chlorpheniramine and Benign Neoplasms

ArticleYear
[Evaluation of short-time premedication with d-chlorpheniramine maleate injection for paclitaxel-induced hypersensitivity reaction].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Chlorpheniramine; Drug Hypersensitivity; Female; Humans; Injections;

2008
Interferon treatment of chronic hepatitis C in patients cured of pediatric malignancies.
    Haematologica, 2000, Volume: 85, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Alanine Transaminase; Alopecia; Asthenia; Chlorpheniramine; DNA, V

2000

Other Studies

4 other studies available for chlorpheniramine and Benign Neoplasms

ArticleYear
AMT: preclinical pharmacology studies.
    International journal of oncology, 2009, Volume: 34, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Calcium; Cells, Cultured; Chamomile; Chlorp

2009
[Protective effects of d-chlorpheniramine maleate pre-treatment against acute side effects of Irinotecan(CPT- 11)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:7

    Topics: Acute Disease; Antineoplastic Agents, Phytogenic; Camptothecin; Chlorpheniramine; Female; Humans; Ir

2011
SOME ANTAGONISTIC EFFECTS OF "HEMATOPORPHYRIN" AND PROTOPORPHYRIN IN MICE.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 116

    Topics: Atropine; Chlorpheniramine; Chlorpromazine; Dinitrophenols; Edetic Acid; Hematoporphyrins; Heparin;

1964
Successful treatment with etoposide phosphate in patients with previous etoposide hypersensitivity.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2008, Volume: 14, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Anti-Inflammatory Agents; Antineoplastic Agents; Chlo

2008