chlorpheniramine has been researched along with Atopic Hypersensitivity in 13 studies
Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ketotifen was significantly more potent in the inhibition of both histamine (P less than 0." | 2.65 | A comparison of the in vivo effects of ketotifen, clemastine, chlorpheniramine and sodium cromoglycate on histamine and allergen induced weals in human skin. ( Davies, RJ; Meyrick Thomas, RH; Moodley, I; Phillips, MJ, 1983) |
| " Bronchial response was monitored with serial measurements of specific airways conductance (sGaw) and a dose-response curve was constructed for each challenge." | 2.65 | The role of histamine receptors in asthma. ( Eiser, NM; Guz, A; Mills, J; Snashall, PD, 1981) |
| ") produced a 12-fold shift in the histamine bronchoconstrictor dose-response curve." | 1.33 | Airway closure after antigen challenge in cynomolgus monkeys: effect of the histamine H1 receptor antagonist, chlorpheniramine maleate. ( Celly, CS; Chapman, RW; Hey, JA; House, A; Lamca, JE; Skeans, S, 2005) |
| "Chlorpheniramine pretreatment prevented death, delayed the onset of respiratory symptoms and decreased the severity of the hypersensitivity reaction." | 1.27 | Use of a simple in vivo technique to investigate components of the immediate hypersensitivity reaction in conscious guinea pigs. ( Hammerbeck, DM; Swingle, KF, 1984) |
| "We tested 5 ABA patients for delayed hypersensitivity to AF." | 1.27 | Participation of cell-mediated immunity in allergic bronchopulmonary aspergillosis. ( Hutcheson, PS; Knutsen, AP; Slavin, RG, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (76.92) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giangrande, N | 1 |
| García-Menaya, JM | 1 |
| Marcos-Fernández, M | 1 |
| Cámara-Hijón, C | 1 |
| Bobadilla-González, P | 1 |
| Skeans, S | 1 |
| Lamca, JE | 1 |
| House, A | 1 |
| Celly, CS | 1 |
| Hey, JA | 1 |
| Chapman, RW | 1 |
| Pincus, SH | 1 |
| DiNapoli, AM | 1 |
| Schooley, WR | 1 |
| Phillips, MJ | 1 |
| Meyrick Thomas, RH | 1 |
| Moodley, I | 1 |
| Davies, RJ | 1 |
| Hammerbeck, DM | 1 |
| Swingle, KF | 1 |
| Eiser, NM | 1 |
| Mills, J | 1 |
| Snashall, PD | 1 |
| Guz, A | 1 |
| Demoly, P | 1 |
| Messaad, D | 1 |
| Benahmed, S | 1 |
| Sahla, H | 1 |
| Bousquet, J | 1 |
| Maibach, HI | 1 |
| Johnson, HL | 1 |
| Abraham, WM | 1 |
| Stevenson, JS | 1 |
| Garrido, R | 1 |
| Slavin, RG | 1 |
| Hutcheson, PS | 1 |
| Knutsen, AP | 1 |
| Schumacher, MJ | 1 |
| Ellis, EF | 1 |
| Jones, HE | 1 |
| Reinhardt, JH | 1 |
| Rinaldi, MG | 1 |
| Kawchak, J | 1 |
2 trials available for chlorpheniramine and Atopic Hypersensitivity
| Article | Year |
|---|---|
A comparison of the in vivo effects of ketotifen, clemastine, chlorpheniramine and sodium cromoglycate on histamine and allergen induced weals in human skin.
Topics: Allergens; Chlorpheniramine; Clemastine; Clinical Trials as Topic; Cromolyn Sodium; Dose-Response Re | 1983 |
The role of histamine receptors in asthma.
Topics: Airway Resistance; Asthma; Bronchial Provocation Tests; Chlorpheniramine; Cimetidine; Dose-Response | 1981 |
11 other studies available for chlorpheniramine and Atopic Hypersensitivity
| Article | Year |
|---|---|
Anaphylaxis due to macrogol in a laxative solution with a positive basophil activation test.
Topics: Aged; Anaphylaxis; Basophil Degranulation Test; Chlorpheniramine; Colonoscopy; Edema; Female; Humans | 2019 |
Airway closure after antigen challenge in cynomolgus monkeys: effect of the histamine H1 receptor antagonist, chlorpheniramine maleate.
Topics: Airway Obstruction; Animals; Ascaris suum; Blood Gas Analysis; Chlorpheniramine; Cross-Over Studies; | 2005 |
Superoxide production by eosinophils: activation by histamine.
Topics: Animals; Chlorpheniramine; Cimetidine; Eosinophils; Guinea Pigs; Histamine; Humans; Hypersensitivity | 1982 |
Use of a simple in vivo technique to investigate components of the immediate hypersensitivity reaction in conscious guinea pigs.
Topics: Aerosols; Anaphylaxis; Animals; Atropine; Bronchial Spasm; Chlorpheniramine; Chromones; Guinea Pigs; | 1984 |
Hypersensitivity to H1-antihistamines.
Topics: Chlorpheniramine; Drug Hypersensitivity; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Hype | 2000 |
Contact urticaria syndrome. Contact urticaria to diethyltoluamide (immediate-type hypersensitivity).
Topics: Adult; Ammonium Sulfate; Atropine; Benzamides; Benzocaine; Chlorpheniramine; DEET; Dermatitis, Conta | 1975 |
A possible role for PAF in allergen-induced late responses: modification by a selective antagonist.
Topics: Aerosols; Allergens; Animals; Antigens, Helminth; Ascaris; Asthma; Azepines; Chlorpheniramine; Chrom | 1989 |
Participation of cell-mediated immunity in allergic bronchopulmonary aspergillosis.
Topics: Administration, Oral; Aspergillosis, Allergic Bronchopulmonary; Aspergillus fumigatus; Chlorpheniram | 1987 |
Leucocyte histamine release studies and skin tests with aggregated gamma-globulin in hypogammaglobulinaemia.
Topics: Adolescent; Adult; Agammaglobulinemia; Animals; Child; Chlorpheniramine; Depression, Chemical; Guine | 1974 |
Immunologic susceptibility to chronic dermatophytosis.
Topics: Antibodies; Chlorpheniramine; Dermatomycoses; Humans; Hypersensitivity, Delayed; Hypersensitivity, I | 1974 |
Prevention of allergic immunization reactions.
Topics: Chlorpheniramine; Drug Hypersensitivity; Emigration and Immigration; Food Hypersensitivity; Humans; | 1966 |