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chlorpheniramine and Asthma

chlorpheniramine has been researched along with Asthma in 51 studies

Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"The effect of an H1 antihistamine, an H2 antihistamine, and the combination of the two drugs on both histamine-induced bronchoconstriction and dermal whealing was examined in five patients with mild asthma."9.05A comparison of the actions of H1 and H2 antihistamines on histamine-induced bronchoconstriction and cutaneous wheal response in asthmatic patients. ( Nathan, RA; Schocket, AL; Segall, N, 1981)
"We compared the effects of two histamine receptor blocking agents, chlorpheniramine (H1) and cimetidine (H2) on the airways of healthy and asthmatic subjects."9.05Histamine blocking agents in healthy and asthmatic subjects. ( Brown, S; Gerstenhaber, B; Lach, E; Schachter, EN, 1982)
"1 Two studies have been carried out to investigate the effect of H1- and H2-receptor blocking agents on histamine-induced bronchoconstriction in non-asthmatic subjects."9.04Effects of H1- and H2-receptor blocking agents on histamine-induced bronchoconstriction in non-asthmatic subjects. ( Maconochie, JG; Richards, DA; Woodings, EP, 1979)
"This study was designed to examine the effect of an H1 antihistamine, chlorpheniramine, an H2 antihistamine, cimetidine, and the combination of chlorpheniramine and cimetidine on histamine-induced bronchoconstriction in a double-blind, randomized protocol on 11 patients with asthma."9.04The effects of H1 and H2 antihistamines on histamine inhalation challenges in asthmatic patients. ( Glover, GC; Nathan, RA; Schocket, AL; Segall, N, 1979)
"This study shows that Chlorpheniramine causes bronchodilation during resting period by acting on the circulating or tissue histamine in asthmatics which contributes to an increase in resting bronchomotor tone."7.96The Effect of Aerosolized Chlorpheniramine Maleate on Exercise Induced Bronchospasm and Gas Exchange in Asthmatics. ( Chugh, J; Kulkarni, HS; Maheshwari, S; Yadav, YR, 2020)
"We examined the effects of pharmacologic antagonists on the bronchial response to inhaled histamine in 11 normal and 11 asthmatic subjects."7.66Histamine dose-response relationships in normal and asthmatic subjects. The importance of starting airway caliber. ( Chung, KF; Keyes, SJ; Morgan, B; Snashall, PD, 1982)
"In 15 asthmatic subjects, flow volume loops were recorded before and after quantitative nebulization of increasing concentration of histamine and allergen, until a threshold response (-delta FEV1 > 10%) was obtained."7.66Effect of an H1 blocker, chlorpheniramine, on inhalation tests with histamine and allergen in allergic asthma. ( Popa, VT, 1980)
"Nine asthmatic patients with a mean age of 14 yr received bronchial challenges with histamine and methacholine."7.66Bronchial hyperreactivity to histamine and methacholine in asthmatic children after inhalation of SCH 1000 and chlorpheniramine maleate. ( Kattan, M; Levison, H; Orange, RP; Woenne, R, 1978)
"Increased bronchial sensitivity to inhaled histamine in asthma is well known."7.65Decreased H2 histamine response of granulocytes of asthmatic patients. ( Busse, WW; Sosman, J, 1977)
"The effect of an H1 antihistamine, an H2 antihistamine, and the combination of the two drugs on both histamine-induced bronchoconstriction and dermal whealing was examined in five patients with mild asthma."5.05A comparison of the actions of H1 and H2 antihistamines on histamine-induced bronchoconstriction and cutaneous wheal response in asthmatic patients. ( Nathan, RA; Schocket, AL; Segall, N, 1981)
"Chlorpheniramine, clemastine and a placebo have been compared for their ability to relieve bronchoconstriction in 14 childhood asthmatics between the ages of 6 and 14 years."5.05Bronchodilator effect of two inhaled H1-receptor antagonists, clemastine and chlorpheniramine, in wheezy school-children. ( Hodges, IG; Milner, AD; Stokes, GM, 1983)
" In 8 asthmatic subjects, dose-response curves were determined to isocapnic hyperventilation of cold air 30 min after inhalation of chlorpheniramine maleate (18 mg nebulized during tidal breathing), 2 doses of atropine sulphate (3 mg and 18 mg nebulized), or placebo."5.05The protective effect of inhaled chlorpheniramine and atropine on bronchoconstriction stimulated by airway cooling. ( Daniel, EE; Hargreave, FE; Morris, M; O'Byrne, PM; Roberts, RS; Thomson, NC, 1983)
"We compared the effects of two histamine receptor blocking agents, chlorpheniramine (H1) and cimetidine (H2) on the airways of healthy and asthmatic subjects."5.05Histamine blocking agents in healthy and asthmatic subjects. ( Brown, S; Gerstenhaber, B; Lach, E; Schachter, EN, 1982)
"1 Two studies have been carried out to investigate the effect of H1- and H2-receptor blocking agents on histamine-induced bronchoconstriction in non-asthmatic subjects."5.04Effects of H1- and H2-receptor blocking agents on histamine-induced bronchoconstriction in non-asthmatic subjects. ( Maconochie, JG; Richards, DA; Woodings, EP, 1979)
"This study was designed to examine the effect of an H1 antihistamine, chlorpheniramine, an H2 antihistamine, cimetidine, and the combination of chlorpheniramine and cimetidine on histamine-induced bronchoconstriction in a double-blind, randomized protocol on 11 patients with asthma."5.04The effects of H1 and H2 antihistamines on histamine inhalation challenges in asthmatic patients. ( Glover, GC; Nathan, RA; Schocket, AL; Segall, N, 1979)
"This study shows that Chlorpheniramine causes bronchodilation during resting period by acting on the circulating or tissue histamine in asthmatics which contributes to an increase in resting bronchomotor tone."3.96The Effect of Aerosolized Chlorpheniramine Maleate on Exercise Induced Bronchospasm and Gas Exchange in Asthmatics. ( Chugh, J; Kulkarni, HS; Maheshwari, S; Yadav, YR, 2020)
"The anti-asthmatic effects of CS-518 (sodium 2-(1-imidazolylmethyl)-4,5-dihydrobenzo[b]thiophene-6-carboxylate) , a specific thromboxane A2 (TXA2) synthase inhibitor, were investigated in the ovalbumin-sensitized guinea pig asthmatic model."3.68Effects of CS-518, a thromboxane synthase inhibitor, on the asthmatic response. ( Iizuka, Y; Itoh, K; Mukaiyama, O; Satoh, Y; Terada, A; Yamaguchi, T, 1993)
"Effects of KB-2413 on experimental asthma and respiration were examined in comparison with ketotifen and chlorpheniramine in guinea pigs."3.67Antiasthmatic effect of 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)benzimidaz ole difumarate (KB-2413), a new antiallergic. ( Fukuda, T; Ito, K; Saito, T, 1984)
"Until the appearance of nonsedating antihistamines such as terfenadine and astemizole, clinical studies of H1 antagonists in the treatment of asthma yielded disappointing results."3.67The European experience with antihistamines in asthma. ( Rafferty, P, 1989)
"In 12 asthmatic (A) and ten normal (N) subjects, we measured the effect of inhaled saline solution, acetylcholine, histamine (H), and chlorpheniramine (CP) on specific airway conductance and forced exploratory flows."3.67Pharmacodynamic aspects of chlorpheniramine-induced bronchodilatation. ( Popa, V, 1988)
"The mechanism for adenosine-induced bronchospasm was investigated in asthmatic patients."3.67Adenosine-induced bronchoconstriction: premedication with chlorpheniramine and nedocromil sodium. ( Brancatisano, M; Brusasco, V; Crimi, E; Crimi, P; Losurdo, E, 1986)
"We examined the effects of pharmacologic antagonists on the bronchial response to inhaled histamine in 11 normal and 11 asthmatic subjects."3.66Histamine dose-response relationships in normal and asthmatic subjects. The importance of starting airway caliber. ( Chung, KF; Keyes, SJ; Morgan, B; Snashall, PD, 1982)
"In 15 asthmatic subjects, flow volume loops were recorded before and after quantitative nebulization of increasing concentration of histamine and allergen, until a threshold response (-delta FEV1 > 10%) was obtained."3.66Effect of an H1 blocker, chlorpheniramine, on inhalation tests with histamine and allergen in allergic asthma. ( Popa, VT, 1980)
"Nine asthmatic patients with a mean age of 14 yr received bronchial challenges with histamine and methacholine."3.66Bronchial hyperreactivity to histamine and methacholine in asthmatic children after inhalation of SCH 1000 and chlorpheniramine maleate. ( Kattan, M; Levison, H; Orange, RP; Woenne, R, 1978)
"Increased bronchial sensitivity to inhaled histamine in asthma is well known."3.65Decreased H2 histamine response of granulocytes of asthmatic patients. ( Busse, WW; Sosman, J, 1977)
" Cumulative log dose-response curves were constructed."2.65Methacholine dose-response curves in normal and asthmatic man: effect of starting conductance and pharmacological antagonism. ( Chung, KF; Snashall, PD, 1984)
" Bronchial response was monitored with serial measurements of specific airways conductance (sGaw) and a dose-response curve was constructed for each challenge."2.65The role of histamine receptors in asthma. ( Eiser, NM; Guz, A; Mills, J; Snashall, PD, 1981)
" In two subjects, log dose-response curves to 2."2.64Bronchodilating activity of an H1 blocker, chlorpheniramine. ( Popa, VT, 1977)
" The cumulative results indicate that the nonsedative antihistamine terfenadine, given orally at a dosage of 60 mg twice daily, is effective in the treatment of seasonal allergic rhinitis in both adults and children."1.27The use of antihistamines for the treatment of airway disease. ( Meltzer, EO, 1988)
" We determined the nebulizer concentration of PAF which reduced specific airway conductance (SGaw) 35% (PC35 SGaw) and the slope of the PAF dose-response curve."1.27Mechanism of platelet activating factor-induced bronchoconstriction in humans. ( Patterson, R; Rubin, AH; Smith, LJ, 1988)

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-199039 (76.47)18.7374
1990's7 (13.73)18.2507
2000's3 (5.88)29.6817
2010's1 (1.96)24.3611
2020's1 (1.96)2.80

Authors

AuthorsStudies
Wang, Y1
Wang, J1
Lin, Y1
Si-Ma, LF1
Wang, DH1
Chen, LG1
Liu, DK1
Chugh, J1
Yadav, YR1
Kulkarni, HS1
Maheshwari, S1
Izumi, N1
Mizuguchi, H1
Umehara, H1
Ogino, S1
Fukui, H1
Chhabra, J1
Li, YZ1
Alkhouri, H1
Blake, AE1
Ge, Q1
Armour, CL1
Hughes, JM1
Nathan, RA2
Segall, N2
Schocket, AL2
Lewiston, NJ1
Johnson, S1
Sloan, E1
Ahmed, T1
Krainson, JP1
Yerger, LD1
Fukuda, T1
Saito, T1
Ito, K1
Hodges, IG1
Milner, AD2
Stokes, GM2
O'Byrne, PM1
Thomson, NC1
Morris, M1
Roberts, RS1
Daniel, EE1
Hargreave, FE1
Chung, KF2
Snashall, PD3
Nakazawa, T2
Irokawa, M1
Nagasawa, T1
Fueki, R2
Kobayashi, S2
Schachter, EN1
Brown, S1
Lach, E1
Gerstenhaber, B1
Morgan, B1
Keyes, SJ1
Eiser, NM1
Mills, J1
Guz, A1
Popa, VT2
Heyneman, CA1
Yamaguchi, T1
Mukaiyama, O1
Itoh, K1
Satoh, Y1
Terada, A1
Iizuka, Y1
Morimoto, R1
Koyama, S1
Tanaka, A1
Horie, T1
Yamatake, Y1
Sasagawa, S1
Yanaura, S3
Kobayashi, N1
Maconochie, JG1
Woodings, EP1
Richards, DA1
Glover, GC1
Nagai, H1
Osuga, K1
Koda, A1
Woenne, R1
Kattan, M1
Orange, RP1
Levison, H1
Busse, WW1
Sosman, J1
Groggins, RC1
Bailey, K1
By, AW1
Lodge, BA1
Tesi, A1
Li, Q1
Wood, SF1
Bugalho de Almeida, A1
Rubin, BK1
LeGatt, DF1
Audette, RJ1
Misawa, M3
Takenouchi, K3
Shirakawa, Y1
Kamishiro, T1
Yoshino, Y1
Kawamura, T1
Rafferty, P1
Abraham, WM1
Stevenson, JS1
Garrido, R1
Schuller, DE1
Turkewitz, D1
Umegae, Y1
Matsui, S1
Popa, V1
Meltzer, EO1
Crimi, E1
Brusasco, V1
Brancatisano, M1
Losurdo, E1
Crimi, P1
Smith, LJ1
Rubin, AH1
Patterson, R1
Hyde, JS1
Floro, LD1
Gross, GN1
Souhrada, JF1
Farr, RS2
Kiyomoto, A1
Iwasawa, Y1
Harigaya, S1
Karlin, JM1
McKee, WD1
Cochrane, CG1

Reviews

4 reviews available for chlorpheniramine and Asthma

ArticleYear
Histamine2-antagonists in allergic disorders.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:6

    Topics: Asthma; Chlorpheniramine; Cimetidine; Clemastine; Clinical Trials as Topic; Drug Therapy, Combinatio

1994
Clinical experience with non-sedating antihistamines in paediatric allergic rhinitis.
    Rhinology. Supplement, 1992, Volume: 13

    Topics: Adolescent; Astemizole; Asthma; Child; Child, Preschool; Chlorpheniramine; Clinical Trials as Topic;

1992
Effect of drugs on histamine release.
    Allergie et immunologie, 1991, Volume: 23, Issue:9

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Asthma; Bronchial Provocation Tests; Calcium; Chl

1991
Adverse effects of antihistamines.
    Postgraduate medicine, 1986, Feb-01, Volume: 79, Issue:2

    Topics: Adolescent; Adult; Aged; Asthma; Brompheniramine; Central Nervous System; Child, Preschool; Chlorphe

1986

Trials

14 trials available for chlorpheniramine and Asthma

ArticleYear
A comparison of the actions of H1 and H2 antihistamines on histamine-induced bronchoconstriction and cutaneous wheal response in asthmatic patients.
    The Journal of allergy and clinical immunology, 1981, Volume: 67, Issue:3

    Topics: Asthma; Bronchial Provocation Tests; Bronchial Spasm; Chlorpheniramine; Cimetidine; Clinical Trials

1981
Bronchodilator effect of two inhaled H1-receptor antagonists, clemastine and chlorpheniramine, in wheezy school-children.
    British journal of diseases of the chest, 1983, Volume: 77, Issue:3

    Topics: Albuterol; Asthma; Bronchi; Child; Child, Preschool; Chlorpheniramine; Clemastine; Clinical Trials a

1983
The protective effect of inhaled chlorpheniramine and atropine on bronchoconstriction stimulated by airway cooling.
    The American review of respiratory disease, 1983, Volume: 128, Issue:4

    Topics: Adult; Asthma; Atropine; Bronchi; Bronchial Provocation Tests; Chlorpheniramine; Clinical Trials as

1983
Methacholine dose-response curves in normal and asthmatic man: effect of starting conductance and pharmacological antagonism.
    Clinical science (London, England : 1979), 1984, Volume: 66, Issue:6

    Topics: Adult; Airway Resistance; Albuterol; Asthma; Atropine; Bronchi; Chlorpheniramine; Dose-Response Rela

1984
Histamine blocking agents in healthy and asthmatic subjects.
    Chest, 1982, Volume: 82, Issue:2

    Topics: Asthma; Bronchi; Bronchial Spasm; Chlorpheniramine; Cimetidine; Forced Expiratory Flow Rates; Guanid

1982
The role of histamine receptors in asthma.
    Clinical science (London, England : 1979), 1981, Volume: 60, Issue:4

    Topics: Airway Resistance; Asthma; Bronchial Provocation Tests; Chlorpheniramine; Cimetidine; Dose-Response

1981
Bronchodilating activity of an H1 blocker, chlorpheniramine.
    The Journal of allergy and clinical immunology, 1977, Volume: 59, Issue:1

    Topics: Aminophylline; Asthma; Barbiturates; Bronchodilator Agents; Chlorpheniramine; Clinical Trials as Top

1977
Effects of H1- and H2-receptor blocking agents on histamine-induced bronchoconstriction in non-asthmatic subjects.
    British journal of clinical pharmacology, 1979, Volume: 7, Issue:3

    Topics: Administration, Oral; Adult; Airway Resistance; Asthma; Chlorpheniramine; Cimetidine; Forced Expirat

1979
The effects of H1 and H2 antihistamines on histamine inhalation challenges in asthmatic patients.
    The American review of respiratory disease, 1979, Volume: 120, Issue:6

    Topics: Adolescent; Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Chlorpheniramine; Cimetid

1979
The bronchodilator effects of chlorpheniramine in childhood asthma.
    British journal of diseases of the chest, 1979, Volume: 73, Issue:3

    Topics: Adolescent; Asthma; Bronchodilator Agents; Child; Chlorpheniramine; Forced Expiratory Volume; Humans

1979
[Effects of inhaled aerosol of platelet activating factor on pulmonary function and airway responsiveness in normal subjects].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1992, Volume: 15, Issue:4

    Topics: Adult; Aerosols; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction

1992
Theophylline and chlorpheniramine in childhood asthma. Dose requirements for children 6 to 12 years (therapeutic orphans) and young adults 13 to 18 years of age receiving cromolyn sodium prophylaxis.
    Annals of allergy, 1974, Volume: 32, Issue:2

    Topics: Adolescent; Age Factors; Asthma; Bronchodilator Agents; Child; Chlorpheniramine; Clinical Trials as

1974
The longterm treatment of an asthmatic patient using phentolamine.
    Chest, 1974, Volume: 66, Issue:4

    Topics: Administration, Oral; Asthma; Atropine; Blood Pressure; Bronchial Spasm; Bronchodilator Agents; Chlo

1974
An investigation of the possible disadvantages of antihistamines in allergic asthma.
    Annals of allergy, 1972, Volume: 30, Issue:2

    Topics: Adolescent; Adult; Asthma; Child; Chlorpheniramine; Clinical Trials as Topic; Female; Histamine H1 A

1972

Other Studies

33 other studies available for chlorpheniramine and Asthma

ArticleYear
Synthesis and antihistamine evaluations of novel loratadine analogues.
    Bioorganic & medicinal chemistry letters, 2011, Aug-01, Volume: 21, Issue:15

    Topics: Animals; Anti-Allergic Agents; Asthma; Guinea Pigs; Histamine; Histamine Antagonists; Ileum; Loratad

2011
The Effect of Aerosolized Chlorpheniramine Maleate on Exercise Induced Bronchospasm and Gas Exchange in Asthmatics.
    The Journal of the Association of Physicians of India, 2020, Volume: 68, Issue:4

    Topics: Asthma; Asthma, Exercise-Induced; Chlorpheniramine; Exercise Test; Histamine Antagonists; Humans; Re

2020
Analysis of disease-dependent sedative profiles of H(1)-antihistamines by large-scale surveillance using the visual analog scale.
    Methods and findings in experimental and clinical pharmacology, 2008, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Butyrophenones; Cetirizine; Child; Chlorpheniram

2008
Histamine and tryptase modulate asthmatic airway smooth muscle GM-CSF and RANTES release.
    The European respiratory journal, 2007, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Aged; Asthma; Bronchi; Cells, Cultured; Chemokine CCL5; Chlorpheniramine; Dinopro

2007
Effect of antihistamine on pulmonary function of children with asthma.
    The Journal of pediatrics, 1982, Volume: 101, Issue:3

    Topics: Adolescent; Adult; Asthma; Child; Chlorpheniramine; Double-Blind Method; Female; Histamine H1 Antago

1982
Functional depression of H2 histamine receptors in sheep with experimental allergic asthma.
    The Journal of allergy and clinical immunology, 1983, Volume: 72, Issue:3

    Topics: Animals; Asthma; Chlorpheniramine; Female; Histamine; Histamine H1 Antagonists; Histamine H2 Antagon

1983
Antiasthmatic effect of 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)benzimidaz ole difumarate (KB-2413), a new antiallergic.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:7

    Topics: Airway Resistance; Anaphylaxis; Animals; Asthma; Benzimidazoles; Chlorpheniramine; Guinea Pigs; Hist

1984
[Effect of H1- and H2-receptor antagonists on late asthmatic responses].
    Arerugi = [Allergy], 1983, Volume: 32, Issue:1

    Topics: Asthma; Chlorpheniramine; Cimetidine; Drug Therapy, Combination; Guanidines; Humans; Male; Middle Ag

1983
Histamine dose-response relationships in normal and asthmatic subjects. The importance of starting airway caliber.
    The American review of respiratory disease, 1982, Volume: 126, Issue:5

    Topics: Adult; Airway Resistance; Albuterol; Asthma; Atropine; Bronchial Provocation Tests; Chlorpheniramine

1982
Effect of an H1 blocker, chlorpheniramine, on inhalation tests with histamine and allergen in allergic asthma.
    Chest, 1980, Volume: 78, Issue:3

    Topics: Adult; Allergens; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Chlorpheniramine; Female; Hi

1980
Effects of CS-518, a thromboxane synthase inhibitor, on the asthmatic response.
    European journal of pharmacology, 1993, May-12, Volume: 236, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Asthma; Bronchial Hyper

1993
[Hypertonic saline induced bronchoconstriction in sensitized rabbits].
    Nihon Kyobu Shikkan Gakkai zasshi, 1996, Volume: 34, Issue:5

    Topics: Animals; Asthma; Atropine; Bronchoconstriction; Chlorpheniramine; Cholinergic Antagonists; Cyclooxyg

1996
The use of newer asthma and allergy medications during pregnancy. The American College of Obstetricians and Gynecologists (ACOG) and The American College of Allergy, Asthma and Immunology (ACAAI).
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2000, Volume: 84, Issue:5

    Topics: Abnormalities, Drug-Induced; Acetates; Administration, Inhalation; Administration, Intranasal; Admin

2000
Involvement of histamine H1- and H2-receptors in induced asthmas in dogs.
    Japanese journal of pharmacology, 1977, Volume: 27, Issue:6

    Topics: Animals; Ascaris; Asthma; Atropine; Bronchi; Chlorpheniramine; Cimetidine; Dogs; Histamine H1 Antago

1977
Inhibition of hypersensitivity reactions by soluble derivatives of baicalein.
    Japanese journal of pharmacology, 1975, Volume: 25, Issue:6

    Topics: Aminophylline; Anaphylaxis; Animals; Antigens; Arthus Reaction; Asthma; Chlorpheniramine; Female; Fl

1975
Bronchial hyperreactivity to histamine and methacholine in asthmatic children after inhalation of SCH 1000 and chlorpheniramine maleate.
    The Journal of allergy and clinical immunology, 1978, Volume: 62, Issue:2

    Topics: Adolescent; Aerosols; Asthma; Atropine Derivatives; Child; Chlorpheniramine; Dose-Response Relations

1978
Decreased H2 histamine response of granulocytes of asthmatic patients.
    The Journal of clinical investigation, 1977, Volume: 59, Issue:6

    Topics: Adult; Asthma; Bronchitis; Chlorpheniramine; Cyclic AMP; Dose-Response Relationship, Drug; Female; G

1977
Description and chromatographic investigation of Mexican medication for arthritis and asthma, including an unusual corticosteroid.
    Journal of chromatography, 1978, Dec-01, Volume: 166, Issue:1

    Topics: Adrenal Cortex Hormones; Arthritis; Asthma; Capsules; Chlorpheniramine; Chromatography, Gas; Chromat

1978
[Clinical study of a product combining a corticoid and antihistaminic drug].
    La Clinica terapeutica, 1977, Jul-15, Volume: 82, Issue:1

    Topics: Adolescent; Adult; Asthma; Betamethasone; Child; Chlorpheniramine; Drug Combinations; Drug Evaluatio

1977
The Mexican asthma cure. Systemic steroids for gullible gringos.
    Chest, 1990, Volume: 97, Issue:4

    Topics: Asthma; Chlorpheniramine; Humans; Mexico; Quackery; Triamcinolone

1990
Effects of mast cell stabilizers on a new bronchial asthma model using compound 48/80 in dogs.
    Japanese journal of pharmacology, 1987, Volume: 44, Issue:2

    Topics: Airway Resistance; Animals; Asthma; Blood Pressure; Chlorpheniramine; Cromolyn Sodium; Cyclohexaneca

1987
Effects of antiallergic drugs on bronchial and cutaneous anaphylaxis in Lewis rats.
    Journal of pharmacobio-dynamics, 1988, Volume: 11, Issue:2

    Topics: Anaphylaxis; Animals; Asthma; Chlorpheniramine; Cromolyn Sodium; Cyclohexanecarboxylic Acids; Diseas

1988
A new bronchial asthma model using calcium ionophore A23187 in guinea pigs.
    Japanese journal of pharmacology, 1989, Volume: 51, Issue:3

    Topics: Administration, Inhalation; Animals; Asthma; Calcimycin; Chlorpheniramine; Chromones; Disease Models

1989
The European experience with antihistamines in asthma.
    Annals of allergy, 1989, Volume: 63, Issue:5

    Topics: Asthma; Benzhydryl Compounds; Chlorpheniramine; Europe; Forced Expiratory Volume; Histamine H1 Antag

1989
A possible role for PAF in allergen-induced late responses: modification by a selective antagonist.
    Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 66, Issue:5

    Topics: Aerosols; Allergens; Animals; Antigens, Helminth; Ascaris; Asthma; Azepines; Chlorpheniramine; Chrom

1989
Effect of combined H-1 and H-2 histamine receptor antagonists on late asthmatic response in an asthmatic patient.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1987, Volume: 24, Issue:6

    Topics: Asthma; Candida albicans; Chlorpheniramine; Cimetidine; Drug Therapy, Combination; Histamine H1 Anta

1987
Pharmacodynamic aspects of chlorpheniramine-induced bronchodilatation.
    Chest, 1988, Volume: 93, Issue:5

    Topics: Acetylcholine; Adult; Asthma; Bronchi; Bronchodilator Agents; Chlorpheniramine; Histamine; Histamine

1988
The use of antihistamines for the treatment of airway disease.
    Cutis, 1988, Oct-27, Volume: 42, Issue:4A

    Topics: Astemizole; Asthma; Benzhydryl Compounds; Benzimidazoles; Child; Chlorpheniramine; Double-Blind Meth

1988
Adenosine-induced bronchoconstriction: premedication with chlorpheniramine and nedocromil sodium.
    European journal of respiratory diseases. Supplement, 1986, Volume: 147

    Topics: Adenosine; Adolescent; Adult; Asthma; Bronchial Provocation Tests; Chlorpheniramine; Female; Humans;

1986
Mechanism of platelet activating factor-induced bronchoconstriction in humans.
    The American review of respiratory disease, 1988, Volume: 137, Issue:5

    Topics: Adolescent; Adult; Asthma; Atropine; Bronchi; Bronchial Provocation Tests; Chlorpheniramine; Dose-Re

1988
Studies on tetrahydroisoquinolines (THI). VI. Effects of trimetoquinol on tracheal and some other smooth muscles.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:1

    Topics: Adrenergic beta-Agonists; Aminophylline; Anaphylaxis; Animals; Asthma; Atropine; Blood Pressure; Bro

1970
The use of antihistamines in asthma.
    Annals of allergy, 1972, Volume: 30, Issue:6

    Topics: Asthma; Child; Child, Preschool; Chlorpheniramine; Diphenhydramine; Histamine H1 Antagonists; Humans

1972
A clinical study of an unusual case of asthma associated with urticaria pigmentosa.
    The Journal of allergy, 1966, Volume: 37, Issue:1

    Topics: Asthma; Blister; Child, Preschool; Chlorpheniramine; Codeine; Histamine; Humans; Male; Methysergide;

1966