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chlorpheniramine and Arrhythmia

chlorpheniramine has been researched along with Arrhythmia in 10 studies

Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.

Research Excerpts

ExcerptRelevanceReference
"Ligation of left anterior descending coronary artery caused various arrhythmias and reduced histamine content in ischemic myocardium in anesthetized cats."7.68[Histamine and early ischemic arrhythmia in anesthetized cats]. ( Fu, SX; Li, YS; Xu, YF, 1990)
"The effects of the H1-receptor antagonists promethazine, mepyramine, and chlorpheniramine on ischemic and reperfusion arrhythmias were studied in the isolated perfused rat heart."7.67Effects of promethazine on ischemic and reperfusion arrhythmias in rat heart. ( Bralet, J; Opie, LH; Rochette, L; Yao-Kouame, J, 1988)
"We suggest histamine plays some role in arrhythmias associated with myocardial infarction in humans."5.27Enhanced adverse electrophysiologic effects of histamine after myocardial infarction in guinea pigs. ( Altman, CB; Bassett, AL; Cameron, JS; Cuevas, J; Gaide, MS; Goad, PL; Myerburg, RJ, 1985)
"Ligation of left anterior descending coronary artery caused various arrhythmias and reduced histamine content in ischemic myocardium in anesthetized cats."3.68[Histamine and early ischemic arrhythmia in anesthetized cats]. ( Fu, SX; Li, YS; Xu, YF, 1990)
"The effects of the H1-receptor antagonists promethazine, mepyramine, and chlorpheniramine on ischemic and reperfusion arrhythmias were studied in the isolated perfused rat heart."3.67Effects of promethazine on ischemic and reperfusion arrhythmias in rat heart. ( Bralet, J; Opie, LH; Rochette, L; Yao-Kouame, J, 1988)
"To evaluate the ability of histamine to induce ventricular arrhythmias, we studied the effects of histamine on ventricular rhythmicity in the isolated guinea pig heart with complete atrioventricular conduction block."3.66Acceleration of idioventricular rhythms by histamine in guinea pig heart: mediation by H2 receptors. ( Levi, R; Zavecz, JH, 1979)
"We suggest histamine plays some role in arrhythmias associated with myocardial infarction in humans."1.27Enhanced adverse electrophysiologic effects of histamine after myocardial infarction in guinea pigs. ( Altman, CB; Bassett, AL; Cameron, JS; Cuevas, J; Gaide, MS; Goad, PL; Myerburg, RJ, 1985)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19907 (70.00)18.7374
1990's1 (10.00)18.2507
2000's2 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jia, L1
Sun, H1
Cardona, I1
Grau, S1
MarĂ­n, M1
Levi, R1
Zavecz, JH1
Xu, YF1
Li, YS2
Fu, SX2
Li, CG1
Rochette, L1
Yao-Kouame, J1
Bralet, J1
Opie, LH1
Cameron, JS1
Gaide, MS1
Goad, PL1
Altman, CB1
Cuevas, J1
Myerburg, RJ1
Bassett, AL1
Rumack, BH1
Anderson, RJ1
Wolfe, R1
Fletcher, EC1
Vestal, BK1
Baum, T1
Eckfeld, DK1
Shropshire, AT1
Rowles, G1
Varner, LL1
Russell, MA1
Bousvaros, G1

Other Studies

10 other studies available for chlorpheniramine and Arrhythmia

ArticleYear
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant

2008
[Sudden death attributed to ventricular arrhytmia induced by an over-the-counter drug for influenza].
    Medicina clinica, 2002, Jun-08, Volume: 119, Issue:1

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Arrhythmias, Cardiac; Chlorpheniramine; Common Cold;

2002
Acceleration of idioventricular rhythms by histamine in guinea pig heart: mediation by H2 receptors.
    Circulation research, 1979, Volume: 44, Issue:6

    Topics: Anaphylaxis; Animals; Arrhythmias, Cardiac; Chlorpheniramine; Cimetidine; Dose-Response Relationship

1979
[Histamine and early ischemic arrhythmia in anesthetized cats].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1990, Volume: 11, Issue:6

    Topics: Animals; Arrhythmias, Cardiac; Cats; Chlorpheniramine; Cimetidine; Female; Histamine; Histamine Rele

1990
[Arrhythmogenic effects of histamine on ischemic hearts of guinea pigs].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1987, Volume: 8, Issue:6

    Topics: Animals; Arrhythmias, Cardiac; Chlorpheniramine; Cimetidine; Cricetinae; Female; Heart Rate; Histami

1987
Effects of promethazine on ischemic and reperfusion arrhythmias in rat heart.
    Fundamental & clinical pharmacology, 1988, Volume: 2, Issue:5

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chlorpheniramine; Cimetidine; Coronary Diseas

1988
Enhanced adverse electrophysiologic effects of histamine after myocardial infarction in guinea pigs.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:2

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Chlorpheniramine; Dimaprit; Electrophysiology; Gui

1985
Ornade and anticholinergic toxicity: hypertension, hallucinations, and arrhythmias.
    Clinical toxicology, 1974, Volume: 7, Issue:6

    Topics: Adolescent; Adult; Arrhythmias, Cardiac; Chlorpheniramine; Clomipramine; Dibenzazepines; Drug Combin

1974
Observations on models used for the evaluation of antiarrhythmic drugs.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 193, Issue:1

    Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutte

1971
Fatal results from diphenylhydantoin administered intravenously.
    JAMA, 1968, Nov-25, Volume: 206, Issue:9

    Topics: Aged; Arrhythmias, Cardiac; Chlorpheniramine; Death, Sudden; Digitalis Glycosides; Dyspnea; Humans;

1968