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chlorpheniramine and Anxiety

chlorpheniramine has been researched along with Anxiety in 7 studies

Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.

Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.

Research Excerpts

ExcerptRelevanceReference
"This study examined the effects of the H1-antagonist chlorpheniramine and the H2-antagonist ranitidine on reinforcement and anxiety-parameters following unilateral injection into the vicinity of the nucleus basalis magnocellularis (NBM)."7.70The H1- and H2-histamine blockers chlorpheniramine and ranitidine applied to the nucleus basalis magnocellularis region modulate anxiety and reinforcement related processes. ( Hasenöhrl, RU; Huston, JP; Knoche, A; Privou, C, 1998)
"Several findings have pointed to the role of histaminergic neurotransmission in the modulation of anxiety-like behaviors and emotional memory."3.81Dorsal hippocampal microinjection of chlorpheniramine reverses the anxiolytic-like effects of l-histidine and impairs emotional memory in mice. ( Canto-de-Souza, L; Garção, DC; Mattioli, R; Romaguera, F, 2015)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Serafim, KR2
Kishi, MS1
Canto-de-Souza, A1
Mattioli, R3
Canto-de-Souza, L1
Garção, DC1
Romaguera, F1
Russo, PS1
Fernandes, CE1
Gianlorenço, AC1
Tokunaga, S1
Tsutsui, R1
Obara, Y1
Ishida, T1
Kamei, C1
Corenblum, B1
Taylor, PJ1
Privou, C1
Knoche, A1
Hasenöhrl, RU1
Huston, JP1
Rosen, S1
Rosenstein, SN1

Other Studies

7 other studies available for chlorpheniramine and Anxiety

ArticleYear
H₁ but not H₂ histamine antagonist receptors mediate anxiety-related behaviors and emotional memory deficit in mice subjected to elevated plus-maze testing.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2013, Volume: 46, Issue:5

    Topics: Animals; Anxiety; Benzothiazoles; Chlorpheniramine; Histamine H1 Antagonists; Histamine H2 Antagonis

2013
Dorsal hippocampal microinjection of chlorpheniramine reverses the anxiolytic-like effects of l-histidine and impairs emotional memory in mice.
    Neuroscience letters, 2015, Feb-05, Volume: 587

    Topics: Animals; Anxiety; Chlorpheniramine; Emotions; Hippocampus; Histamine; Histamine H1 Antagonists; Male

2015
Intra-amygdala microinjections of chlorpheniramine impair memory formation or memory retrieval in anxiety- and fear-mediated models.
    Brain research bulletin, 2016, Volume: 125

    Topics: Amygdala; Animals; Anxiety; Avoidance Learning; Chlorpheniramine; Disease Models, Animal; Fear; Hist

2016
Effects of histamine H1-antagonists on sleep-awake state in rats placed on a grid suspended over water or on sawdust.
    Biological & pharmaceutical bulletin, 2009, Volume: 32, Issue:1

    Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Chlorpheniramine; Diphenhydramine; Disease

2009
Mechanisms of control of prolactin release in response to apprehension stress and anesthesia-surgery stress.
    Fertility and sterility, 1981, Volume: 36, Issue:6

    Topics: Adult; Anesthesia; Anxiety; Chlorpheniramine; Cyproheptadine; Female; Humans; Naloxone; Pimozide; Pr

1981
The H1- and H2-histamine blockers chlorpheniramine and ranitidine applied to the nucleus basalis magnocellularis region modulate anxiety and reinforcement related processes.
    Neuropharmacology, 1998, Volume: 37, Issue:8

    Topics: Animals; Anxiety; Behavior, Animal; Chlorpheniramine; Histamine H1 Antagonists; Histamine H2 Antagon

1998
Premedication as an adjunct in the dental management of patients with severe cerebral palsy.
    Journal of oral therapeutics and pharmacology, 1966, Volume: 3, Issue:3

    Topics: Adolescent; Adult; Anxiety; Cerebral Palsy; Child; Chlorpheniramine; Chlorpromazine; Fear; Humans; H

1966