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chlorpheniramine and Airway Obstruction

chlorpheniramine has been researched along with Airway Obstruction in 3 studies

Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.

Airway Obstruction: Any hindrance to the passage of air into and out of the lungs.

Research Excerpts

ExcerptRelevanceReference
"The new potent H1 receptor antagonist, LY188695 (KB2413), was delivered to guinea pigs as a pulmonary aerosol and its ability to inhibit histamine-induced airway obstruction examined."3.67Pulmonary aerosol actions of LY188695 (KB2413), a new potent H1-receptor antagonist. ( Rinkema, LE; Silbaugh, SA; Stengel, PW, 1987)
") produced a 12-fold shift in the histamine bronchoconstrictor dose-response curve."1.33Airway closure after antigen challenge in cynomolgus monkeys: effect of the histamine H1 receptor antagonist, chlorpheniramine maleate. ( Celly, CS; Chapman, RW; Hey, JA; House, A; Lamca, JE; Skeans, S, 2005)
"Acute airway obstruction and severe stridor ensued which required tracheal intubation and transfer to paediatric intensive care."1.32Massive tongue swelling following the use of synthetic saliva. ( Kandala, V; Playfor, S, 2003)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kandala, V1
Playfor, S1
Skeans, S1
Lamca, JE1
House, A1
Celly, CS1
Hey, JA1
Chapman, RW1
Silbaugh, SA1
Stengel, PW1
Rinkema, LE1

Other Studies

3 other studies available for chlorpheniramine and Airway Obstruction

ArticleYear
Massive tongue swelling following the use of synthetic saliva.
    Paediatric anaesthesia, 2003, Volume: 13, Issue:9

    Topics: Airway Obstruction; Angioedema; Anti-Inflammatory Agents; Bronchodilator Agents; Cerebral Palsy; Chi

2003
Airway closure after antigen challenge in cynomolgus monkeys: effect of the histamine H1 receptor antagonist, chlorpheniramine maleate.
    International archives of allergy and immunology, 2005, Volume: 137, Issue:1

    Topics: Airway Obstruction; Animals; Ascaris suum; Blood Gas Analysis; Chlorpheniramine; Cross-Over Studies;

2005
Pulmonary aerosol actions of LY188695 (KB2413), a new potent H1-receptor antagonist.
    Agents and actions, 1987, Volume: 21, Issue:1-2

    Topics: Aerosols; Airway Obstruction; Animals; Atropine; Benzimidazoles; Bronchial Provocation Tests; Bronch

1987