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chlorpheniramine and Acute Liver Injury, Drug-Induced

chlorpheniramine has been researched along with Acute Liver Injury, Drug-Induced in 8 studies

Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's5 (62.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fourches, D1
Barnes, JC1
Day, NC1
Bradley, P1
Reed, JZ1
Tropsha, A1
Morgan, RE2
Trauner, M1
van Staden, CJ2
Lee, PH1
Ramachandran, B1
Eschenberg, M1
Afshari, CA2
Qualls, CW1
Lightfoot-Dunn, R1
Hamadeh, HK2
Liu, Z1
Shi, Q1
Ding, D1
Kelly, R1
Fang, H1
Tong, W2
Chen, Y1
Kalyanaraman, N1
Kalanzi, J1
Dunn, RT1
Chen, M1
Suzuki, A1
Thakkar, S1
Yu, K1
Hu, C1
Kirages, TJ1
Sulé, HP1
Mycyk, MB1
Nomura, A1
Sakurai, E1
Hikichi, N1
Remy, AJ1
Debette, M1
Diaz, D1
Voigt, JJ1
Blanc, P1
Larrey, D1

Reviews

1 review available for chlorpheniramine and Acute Liver Injury, Drug-Induced

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr

2016

Other Studies

7 other studies available for chlorpheniramine and Acute Liver Injury, Drug-Induced

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters

2010
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily

2013
Severe manifestations of coricidin intoxication.
    The American journal of emergency medicine, 2003, Volume: 21, Issue:6

    Topics: Acetaminophen; Adolescent; Antidepressive Agents; Chemical and Drug Induced Liver Injury; Chlorpheni

2003
[Effect of carbon tetrachloride-induced hepatic injury on stereoselective N-demethylation of chlorpheniramine by rat hepatic cytochrome P450 2C11 isozyme].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1998, Volume: 118, Issue:8

    Topics: Animals; Anti-Allergic Agents; Aryl Hydrocarbon Hydroxylases; Biotransformation; Carbon Tetrachlorid

1998
[Dexchlorpheniramine-induced acute hepatitis: a case with positive rechallenge].
    Gastroenterologie clinique et biologique, 1998, Volume: 22, Issue:10

    Topics: Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Chlorpheniramine; Histamine H1 Antagon

1998