chlorpheniramine has been researched along with Acute Disease in 24 studies
Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of chloroquine (CQ), amodiaquine (AQ) and CQ plus chlorpheniramine (a histamine H(1) antagonist that reverses CQ resistance in vitro and in vivo) on the disposition of the enlarged liver associated with acute, symptomatic, uncomplicated, Plasmodium falciparum malaria were evaluated." | 9.10 | The effects of chloroquine, amodiaquine and chloroquine plus chlorpheniramine on the disposition kinetics of the hepatomegaly associated with acute, uncomplicated, Plasmodium falciparum malaria in children. ( Adedeji, AA; Sowunmi, A, 2002) |
| "Adult ED patients with acute urticaria and a pruritus score > 5 on a visual analog scale (VAS) were randomized into three groups: (i) IV chlorpheniramine (CPM) treatment, (ii) IV CPM and IV dexamethasone (CPM/Dex) and (iii) IV CPM and IV dexamethasone with oral prednisolone as discharge medication for 5 days (CPM/Dex/Pred)." | 5.41 | A randomized controlled trial of adding intravenous corticosteroids to H1 antihistamines in patients with acute urticaria. ( Musikatavorn, K; Palungwachira, P; Vilaisri, K; Wongpiyabovorn, J, 2021) |
| "The effects of chloroquine (CQ), amodiaquine (AQ) and CQ plus chlorpheniramine (a histamine H(1) antagonist that reverses CQ resistance in vitro and in vivo) on the disposition of the enlarged liver associated with acute, symptomatic, uncomplicated, Plasmodium falciparum malaria were evaluated." | 5.10 | The effects of chloroquine, amodiaquine and chloroquine plus chlorpheniramine on the disposition kinetics of the hepatomegaly associated with acute, uncomplicated, Plasmodium falciparum malaria in children. ( Adedeji, AA; Sowunmi, A, 2002) |
| "Clinical outcomes and recurrence rates did not differ significantly with treatment." | 2.71 | A randomized, placebo-controlled trial of the effect of antihistamine or corticosteroid treatment in acute otitis media. ( Baldwin, CD; Chonmaitree, T; Freeman, DH; Heikkinen, T; McCormick, DP; Saeed, K; Uchida, T, 2003) |
| " The present work suggests that Rhinopront is an effective nasal decongestant in adults and children with acute congestive rhinitis and supports the adequacy of the proposed twice-daily dosing rate." | 2.67 | Exploratory study of the decongestive effect of Rhinopront syrup in adults and in children with acute rhinitis. ( Calderon, P; Deroubaix, X; Gline, JP; Joue, P; Lebacq, E; Schwegler, F; Stockis, A; Van Schoor, O, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (29.17) | 18.7374 |
| 1990's | 3 (12.50) | 18.2507 |
| 2000's | 10 (41.67) | 29.6817 |
| 2010's | 3 (12.50) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Palungwachira, P | 1 |
| Vilaisri, K | 1 |
| Musikatavorn, K | 1 |
| Wongpiyabovorn, J | 1 |
| Sharawat, IK | 1 |
| Suthar, R | 1 |
| Sato, M | 1 |
| Misumi, N | 1 |
| Hiraike, M | 1 |
| Nawata, F | 1 |
| Hashimoto, M | 1 |
| Tanigawa, K | 1 |
| Takase, I | 1 |
| Nabeshima, A | 1 |
| Honda, S | 1 |
| Sowunmi, A | 3 |
| Adedeji, AA | 3 |
| McCormick, DP | 2 |
| Saeed, K | 2 |
| Uchida, T | 2 |
| Baldwin, CD | 2 |
| Deskin, R | 1 |
| Lett-Brown, MA | 1 |
| Heikkinen, T | 2 |
| Chonmaitree, T | 2 |
| Freeman, DH | 1 |
| Fateye, BA | 2 |
| Fehintola, FA | 1 |
| Gbotosho, GO | 2 |
| Happi, TC | 2 |
| Oduola, AM | 2 |
| Sharma, A | 1 |
| Dewan, V | 1 |
| Petty, F | 1 |
| Bhalla, M | 1 |
| Thami, GP | 1 |
| Moriyasu, S | 1 |
| Yamamoto, K | 1 |
| Kureyama, N | 1 |
| Okamura, K | 1 |
| Ikeda, T | 1 |
| Yamatodani, A | 1 |
| Samieh-Tucker, A | 1 |
| Rupasinghe, M | 1 |
| Falade, CO | 1 |
| Michael, SO | 1 |
| Lampe, RM | 1 |
| Weir, MR | 1 |
| McLeod, HL | 1 |
| Artalejo, L | 1 |
| Court, H | 1 |
| Streete, P | 1 |
| Volans, GN | 1 |
| Rumiantsev, AG | 1 |
| Aldonina, VV | 1 |
| Ilína, TP | 1 |
| Snitsarenko, VIu | 1 |
| Biriuchinskaia, IG | 1 |
| Shevaldina, TV | 1 |
| Remy, AJ | 1 |
| Debette, M | 1 |
| Diaz, D | 1 |
| Voigt, JJ | 1 |
| Blanc, P | 1 |
| Larrey, D | 1 |
| Lebacq, E | 1 |
| Gline, JP | 1 |
| Joue, P | 1 |
| Stockis, A | 1 |
| Calderon, P | 1 |
| Van Schoor, O | 1 |
| Deroubaix, X | 1 |
| Schwegler, F | 1 |
| Hinkelmann, B | 1 |
| Schumann, K | 1 |
| Howie, VM | 1 |
| Ploussard, JH | 1 |
| Riff, LJ | 1 |
| Stickler, GB | 1 |
| Rubenstein, MM | 1 |
| McBean, JB | 1 |
| Hedgecock, LD | 1 |
| Hugstad, JA | 1 |
| Griffing, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000363] | Phase 3 | 0 participants | Interventional | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for chlorpheniramine and Acute Disease
| Article | Year |
|---|---|
Chemotherapy in ear disease.
Topics: Acute Disease; Child; Child, Preschool; Chlorpheniramine; Chronic Disease; Ear, Middle; Enterobacter | 1972 |
11 trials available for chlorpheniramine and Acute Disease
| Article | Year |
|---|---|
A randomized controlled trial of adding intravenous corticosteroids to H1 antihistamines in patients with acute urticaria.
Topics: Acute Disease; Administration, Intravenous; Administration, Oral; Adolescent; Adrenal Cortex Hormone | 2021 |
The effects of chloroquine, amodiaquine and chloroquine plus chlorpheniramine on the disposition kinetics of the hepatomegaly associated with acute, uncomplicated, Plasmodium falciparum malaria in children.
Topics: Acute Disease; Adolescent; Amodiaquine; Antimalarials; Area Under Curve; Child; Child, Preschool; Ch | 2002 |
Middle ear fluid histamine and leukotriene B4 in acute otitis media: effect of antihistamine or corticosteroid treatment.
Topics: Acute Disease; Anti-Bacterial Agents; Anti-Inflammatory Agents; Ceftriaxone; Child; Child, Preschool | 2003 |
A randomized, placebo-controlled trial of the effect of antihistamine or corticosteroid treatment in acute otitis media.
Topics: Acute Disease; Anti-Bacterial Agents; Anti-Inflammatory Agents; Ceftriaxone; Child; Child, Preschool | 2003 |
Predictors of the failure of treatment with chloroquine plus chlorpheniramine, in children with acute, uncomplicated, Plasmodium falciparum malaria.
Topics: Acute Disease; Age Factors; Antimalarials; Child; Child, Preschool; Chloroquine; Chlorpheniramine; D | 2005 |
Enhanced efficacy of amodiaquine and chlorpheniramine combination over amodiaquine alone in the treatment of acute uncomplicated Plasmodium falciparum malaria in children.
Topics: Acute Disease; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chlorpheniramine; Drug | 2008 |
A clinical trial of antihistamine, decongestant, or placebo in antibiotic-treated acute otitis media followed with pneumatic otoscopy and impedance tympanometry.
Topics: Acoustic Impedance Tests; Acute Disease; Ampicillin; Child, Preschool; Chlorpheniramine; Clinical Tr | 1981 |
[Use of coldact, a long-acting preparation of NATKO for the treatment of upper respiratory tract diseases in outpatient clinics].
Topics: Acute Disease; Adult; Ambulatory Care; Child; Chlorpheniramine; Delayed-Action Preparations; Drug Co | 1994 |
Exploratory study of the decongestive effect of Rhinopront syrup in adults and in children with acute rhinitis.
Topics: Acute Disease; Adult; Airway Resistance; Capsules; Child; Chlorpheniramine; Delayed-Action Preparati | 1994 |
Efficacy of fixed combination antibiotics versus separate components in otitis media. Effectiveness of erythromycin estrolate, triple sulfonamide, ampicillin, erythromycin estolate- triple sulfonamide, and placebo in 280 patients with acute otitis media u
Topics: Acetaminophen; Acute Disease; Ampicillin; Child, Preschool; Chlorpheniramine; Drug Combinations; Ery | 1972 |
Treatment of acute otitis media in children. IV. A fourth clinical trial.
Topics: Acute Disease; Child; Child, Preschool; Chlorpheniramine; Drug Therapy, Combination; Female; Humans; | 1967 |
12 other studies available for chlorpheniramine and Acute Disease
| Article | Year |
|---|---|
Drug Induced Acute Dystonic Reaction.
Topics: Acetaminophen; Acute Disease; Antipyretics; Child, Preschool; Chlorpheniramine; Dystonia; Histamine | 2018 |
[Acute histamine poisoning caused by rice bran pickle of mackerel pike: a case report].
Topics: Acute Disease; Chlorpheniramine; Female; Fish Products; Histamine; Histamine Antagonists; Humans; Mi | 2011 |
[Protective effects of d-chlorpheniramine maleate pre-treatment against acute side effects of Irinotecan(CPT- 11)].
Topics: Acute Disease; Antineoplastic Agents, Phytogenic; Camptothecin; Chlorpheniramine; Female; Humans; Ir | 2011 |
Acute psychosis with Coricidin cold medicine.
Topics: Acute Disease; Antitussive Agents; Chlorpheniramine; Dextromethorphan; Drug Combinations; Histamine | 2005 |
Acute urticaria following 'gomutra' (cow's urine) gargles.
Topics: Acute Disease; Adult; Animals; Anti-Allergic Agents; Cattle; Chlorpheniramine; Complementary Therapi | 2005 |
Effects of pyrimethamine-sulphadoxine, chloroquine plus chlorpheniramine, and amodiaquine plus pyrimethamine-sulphadoxine on gametocytes during and after treatment of acute, uncomplicated malaria in children.
Topics: Acute Disease; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Chlorpheni | 2006 |
Involvement of histamine released from mast cells in acute radiation dermatitis in mice.
Topics: Acute Disease; Animals; Chlorpheniramine; Dose-Response Relationship, Drug; Edema; Erythema; Hair Re | 2007 |
Anaesthesia for caesarean section in a patient with acute generalised pustular psoriasis.
Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Gener | 2007 |
Acute poisoning with ibuprofen.
Topics: Acute Disease; Adolescent; Adult; Aged; Child; Child, Preschool; Chlorpheniramine; Diazepam; Female; | 1983 |
[Dexchlorpheniramine-induced acute hepatitis: a case with positive rechallenge].
Topics: Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Chlorpheniramine; Histamine H1 Antagon | 1998 |
[Treatment of acute nonspecific rhinitis. Studies on the long-term effect of Cimporhin].
Topics: Acute Disease; Analgesics; Anti-Inflammatory Agents; Bronchitis; Chlorpheniramine; Drug Combinations | 1972 |
[The action of an oral rhinological agent on the nasal mucous membrane (author's transl)].
Topics: Acute Disease; Analgesics; Chlorpheniramine; Drug Combinations; Histamine H1 Antagonists; Imidazoles | 1974 |