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chlorothiazide and Myocardial Infarction

chlorothiazide has been researched along with Myocardial Infarction in 10 studies

Chlorothiazide: A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
thiazide : Heterocyclic compound with sulfur and nitrogen in the ring.
chlorothiazide : 4H-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position is substituted by chlorine and that at position 7 is substituted by a sulfonamide group. A diuretic, it is used for treatment of oedema and hypertension.

Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).

Research Excerpts

ExcerptRelevanceReference
" The effects of prolonged chlorothiazide treatment of left ventricular failure on cardiac hypertrophy, circulating vasoactive hormones and exchangeable body sodium were examined in rats with chronic myocardial infarction induced by left coronary artery ligation."7.69Cardiomegaly and vasoactive hormones in rats with chronic myocardial infarction: long-term effects of chlorothiazide. ( Abe, K; Johnston, CI; Kanazawa, M; Kohzuki, M; Sato, T; Tsutsumi, E; Yasujima, M; Yoshida, K, 1996)
"The long-term effects of perindopril or chlorothiazide therapy were studied in rats after the induction of myocardial infarction by coronary artery ligation."7.68Comparative effects of angiotensin converting enzyme inhibition (perindopril) or diuretic therapy on cardiac hypertrophy and sympathetic activity following myocardial infarction in rats. ( Hodsman, GP; Howes, LG; Johnston, CI; Rowe, PR, 1991)
" Some of this information includes: the unexpected yet very real hazards as well as benefits associated with the long-term use of powerful drugs, in particular the original description of hydralazine-induced lupus, its relation to genetic markers and its association with control of hypertension; the apparently decreasing need for antihypertensive drugs in subjects with well-controlled severe and moderate hypertension; the identification of risk factors for the complications of hypertension and the quantitation of their effects; the decrease in the incidence of hypertensive complications associated with the pharmacologic treatment of severe, moderate and, at least, the upper ranges of mild hypertension; the possibility of designing a chemical to block a specific reaction and the realization that it would have broader than expected effects; and the primary prevention of myocardial infarction in very high risk subjects."4.77The evolution of antihypertensive therapy. ( Perry, HM, 1985)
" The effects of prolonged chlorothiazide treatment of left ventricular failure on cardiac hypertrophy, circulating vasoactive hormones and exchangeable body sodium were examined in rats with chronic myocardial infarction induced by left coronary artery ligation."3.69Cardiomegaly and vasoactive hormones in rats with chronic myocardial infarction: long-term effects of chlorothiazide. ( Abe, K; Johnston, CI; Kanazawa, M; Kohzuki, M; Sato, T; Tsutsumi, E; Yasujima, M; Yoshida, K, 1996)
"The long-term effects of perindopril or chlorothiazide therapy were studied in rats after the induction of myocardial infarction by coronary artery ligation."3.68Comparative effects of angiotensin converting enzyme inhibition (perindopril) or diuretic therapy on cardiac hypertrophy and sympathetic activity following myocardial infarction in rats. ( Hodsman, GP; Howes, LG; Johnston, CI; Rowe, PR, 1991)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19908 (80.00)18.7374
1990's2 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
GADBOYS, HL1
WISOFF, G1
LITWAK, RS1
Kohzuki, M1
Kanazawa, M1
Yoshida, K1
Tsutsumi, E1
Yasujima, M1
Abe, K1
Johnston, CI2
Sato, T1
Morgan, T1
Adam, W1
Carney, S1
Gibbard, R1
Brown, S1
Wheeler, D1
Smith, WM1
Howes, LG1
Hodsman, GP1
Rowe, PR1
Perry, HM1
Morgan, TO1
Kattus, AA1
Kiesewetter, E1
Scatasta, M1

Reviews

1 review available for chlorothiazide and Myocardial Infarction

ArticleYear
The evolution of antihypertensive therapy.
    The American journal of cardiology, 1985, Dec-06, Volume: 56, Issue:16

    Topics: Antihypertensive Agents; Bis-Trimethylammonium Compounds; Blood Pressure; Calcium Channel Blockers;

1985

Trials

2 trials available for chlorothiazide and Myocardial Infarction

ArticleYear
Treatment of mild hypertension in elderly males.
    Clinical science (London, England : 1979), 1979, Volume: 57 Suppl 5

    Topics: Adrenergic beta-Antagonists; Aged; Blood Pressure; Chlorothiazide; Diet, Sodium-Restricted; Humans;

1979
Treatment of mild hypertension: results of a ten-year intervention trial.
    Circulation research, 1977, Volume: 40, Issue:5 Suppl 1

    Topics: Adult; Blood Pressure; Cardiomegaly; Cerebrovascular Disorders; Chlorothiazide; Clinical Trials as T

1977

Other Studies

7 other studies available for chlorothiazide and Myocardial Infarction

ArticleYear
SURGICAL TREATMENT OF COMPLETE HEART BLOCK. AN ANALYSIS OF 36 CASES.
    JAMA, 1964, Jul-13, Volume: 189

    Topics: Atropine; Chlorothiazide; Diabetes Mellitus; Ephedrine; Geriatrics; Heart Block; Heart Failure; Huma

1964
Cardiomegaly and vasoactive hormones in rats with chronic myocardial infarction: long-term effects of chlorothiazide.
    Clinical science (London, England : 1979), 1996, Volume: 90, Issue:1

    Topics: Animals; Arginine Vasopressin; Atrial Natriuretic Factor; Cardiomegaly; Chlorothiazide; Chronic Dise

1996
Comparative effects of angiotensin converting enzyme inhibition (perindopril) or diuretic therapy on cardiac hypertrophy and sympathetic activity following myocardial infarction in rats.
    Cardiovascular drugs and therapy, 1991, Volume: 5, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiomegaly; Chlorothiazide; Female; Indoles; Me

1991
Diuretics and myocardial infarction or sudden death.
    Drugs, 1986, Volume: 31 Suppl 4

    Topics: Chlorothiazide; Death, Sudden; Humans; Hypertension; Male; Methyldopa; Middle Aged; Myocardial Infar

1986
Exercise electrocardiography: recognition of the ischemic response, false positive and negative patterns.
    The American journal of cardiology, 1974, May-20, Volume: 33, Issue:6

    Topics: Action Potentials; Angina Pectoris; Arteriosclerosis; Chlorothiazide; Coronary Disease; Diagnostic E

1974
[Physiopathological deliberations on the significance of long-term therapy for hypertension].
    Wiener klinische Wochenschrift, 1967, Nov-03, Volume: 79, Issue:44

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Cerebrovascular Disorders; Chlorothiazide; Fem

1967
[Gout and myocardial infarct. Preliminary note].
    Minerva medica, 1966, Mar-07, Volume: 57, Issue:19

    Topics: Chlorothiazide; Diuretics; Gout; Humans; Myocardial Infarction; Purines

1966