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chlorothiazide and Lupus Erythematosus, Systemic

chlorothiazide has been researched along with Lupus Erythematosus, Systemic in 7 studies

Chlorothiazide: A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
thiazide : Heterocyclic compound with sulfur and nitrogen in the ring.
chlorothiazide : 4H-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position is substituted by chlorine and that at position 7 is substituted by a sulfonamide group. A diuretic, it is used for treatment of oedema and hypertension.

Lupus Erythematosus, Systemic: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.

Research Excerpts

ExcerptRelevanceReference
" Some of this information includes: the unexpected yet very real hazards as well as benefits associated with the long-term use of powerful drugs, in particular the original description of hydralazine-induced lupus, its relation to genetic markers and its association with control of hypertension; the apparently decreasing need for antihypertensive drugs in subjects with well-controlled severe and moderate hypertension; the identification of risk factors for the complications of hypertension and the quantitation of their effects; the decrease in the incidence of hypertensive complications associated with the pharmacologic treatment of severe, moderate and, at least, the upper ranges of mild hypertension; the possibility of designing a chemical to block a specific reaction and the realization that it would have broader than expected effects; and the primary prevention of myocardial infarction in very high risk subjects."4.77The evolution of antihypertensive therapy. ( Perry, HM, 1985)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19907 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KNOX, JM1
Sparberg, M1
Perry, HM1
Simone, JV1
Cornet, JA1
Abildgaard, CF1
Tuerk, M1
Heimpel, H1
Erdmann, H1
Karpatkin, S1
Strick, N1
Karpatkin, MB1
Siskind, GW1

Reviews

1 review available for chlorothiazide and Lupus Erythematosus, Systemic

ArticleYear
The evolution of antihypertensive therapy.
    The American journal of cardiology, 1985, Dec-06, Volume: 56, Issue:16

    Topics: Antihypertensive Agents; Bis-Trimethylammonium Compounds; Blood Pressure; Calcium Channel Blockers;

1985

Other Studies

6 other studies available for chlorothiazide and Lupus Erythematosus, Systemic

ArticleYear
PHOTOSENSITIVITY--A COMMON PHYSICAL ALLERGY.
    Southern medical journal, 1964, Volume: 57

    Topics: 4-Aminobenzoic Acid; Aminobenzoates; Anti-Bacterial Agents; Antimalarials; Chlorothiazide; Chlorprop

1964
Recurrent acute pancreatitis associated with systemic lupus erythematosus. Report of a case.
    The American journal of digestive diseases, 1967, Volume: 12, Issue:5

    Topics: Adrenal Cortex Hormones; Adult; Chlorothiazide; Female; Humans; Lupus Erythematosus, Systemic; Pancr

1967
Acquired von Willebrand's syndrome in systemic lupus erythematosus.
    Blood, 1968, Volume: 31, Issue:6

    Topics: Adolescent; Blood Cell Count; Blood Chemical Analysis; Blood Coagulation Tests; Chlorothiazide; Hemo

1968
Skin grafting in systemic lupus erythematosus patients who are on steroids.
    Plastic and reconstructive surgery, 1972, Volume: 50, Issue:4

    Topics: Adult; Azathioprine; Chlorothiazide; Debridement; Female; Guanethidine; Humans; Leg Injuries; Lupus

1972
[Immune thrombocytopenia].
    Medizinische Klinik, 1970, Apr-17, Volume: 65, Issue:16

    Topics: Acetazolamide; Anemia, Hemolytic, Autoimmune; Autoantibodies; Autoimmune Diseases; Blood Coagulation

1970
Cumulative experience in the detection of antiplatelet antibody in 234 patients with idiopathic thrombocytopenic purpura, systemic lupus erythematosus and other clinical disorders.
    The American journal of medicine, 1972, Volume: 52, Issue:6

    Topics: Adult; Animals; Antibody Specificity; Autoantibodies; Blood Coagulation Tests; Blood Platelet Disord

1972