chlorothiazide has been researched along with Hypophosphatasia in 2 studies
Chlorothiazide: A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
thiazide : Heterocyclic compound with sulfur and nitrogen in the ring.
chlorothiazide : 4H-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position is substituted by chlorine and that at position 7 is substituted by a sulfonamide group. A diuretic, it is used for treatment of oedema and hypertension.
Hypophosphatasia: A genetic metabolic disorder resulting from serum and bone alkaline phosphatase deficiency leading to hypercalcemia, ethanolamine phosphatemia, and ethanolamine phosphaturia. Clinical manifestations include severe skeletal defects resembling vitamin D-resistant rickets, failure of the calvarium to calcify, dyspnea, cyanosis, vomiting, constipation, renal calcinosis, failure to thrive, disorders of movement, beading of the costochondral junction, and rachitic bone changes. (From Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypercalcemia is hypothesized to be related to normal bone resorption in conjunction with impaired bone mineralization." | 1.30 | Infantile hypophosphatasia: treatment options to control hypercalcemia, hypercalciuria, and chronic bone demineralization. ( Barcia, JP; Langman, CB; Strife, CF, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barcia, JP | 1 |
| Strife, CF | 1 |
| Langman, CB | 1 |
| Deeb, AA | 1 |
| Bruce, SN | 1 |
| Morris, AA | 1 |
| Cheetham, TD | 1 |
2 other studies available for chlorothiazide and Hypophosphatasia
| Article | Year |
|---|---|
Infantile hypophosphatasia: treatment options to control hypercalcemia, hypercalciuria, and chronic bone demineralization.
Topics: Bone Resorption; Calcitonin; Calcium; Chlorothiazide; Diuretics; Female; Humans; Hypercalcemia; Hypo | 1997 |
Infantile hypophosphatasia: disappointing results of treatment.
Topics: Alkaline Phosphatase; Calcitonin; Calcium, Dietary; Chlorothiazide; Clodronic Acid; Diuretics; Drug | 2000 |