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chlorothiazide and Hepatic Encephalopathy

chlorothiazide has been researched along with Hepatic Encephalopathy in 18 studies

Chlorothiazide: A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
thiazide : Heterocyclic compound with sulfur and nitrogen in the ring.
chlorothiazide : 4H-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position is substituted by chlorine and that at position 7 is substituted by a sulfonamide group. A diuretic, it is used for treatment of oedema and hypertension.

Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)

Research Excerpts

ExcerptRelevanceReference
"A very rare case of acute pancreatitis with concurrent encephalomalacia and ascites mimicking hepatic coma is described."1.25Silent acute pancreatitis with encephalomalacia mimicking hepatic coma. ( Cohen, L; Rosenfeld, JB; Sandbank, U, 1975)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199018 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mackie, JE1
Stormont, JM1
Hollister, RM1
Davidson, CS1
SCHAUS, R1
SATALINE, LR1
WARREN, KS1
SCHENKER, S1
TOBE, BA1
GOLDMAN, BS1
STERNBERG, MS1
HAGEDORN, CW1
KALSER, MH1
NIENHUIS, LI1
MULMED, EI1
KELLEY, JW1
BAGROS, P1
HAUFTOVA, D1
JONES, PN1
CAPPS, RB1
CASEY, TH1
SUMMERSKILL, WH1
BICKFORD, RG1
ROSEVEAR, JW1
READ, AE1
LAIDLAW, J1
HASLAM, RM1
SHERLOCK, S3
Cohen, L1
Sandbank, U1
Rosenfeld, JB1
Senewiratne, B2
Scott, A2
Walker, JG2
Leemhuis, MP1
Struyvenberg, A1
Szám, I1
Aneckstein, AG1
Weingold, AB1

Reviews

3 reviews available for chlorothiazide and Hepatic Encephalopathy

ArticleYear
HEPATIC COMA; TREATMENT EMPHASIZING MERIT OF PERITONEAL DIALYSIS.
    American journal of surgery, 1963, Volume: 106

    Topics: Adrenal Cortex Hormones; Alkalosis; Ammonium Chloride; Anti-Bacterial Agents; Arginine; Chlorothiazi

1963
[HEPATIC COMA].
    Vnitrni lekarstvi, 1964, Volume: 10

    Topics: Acetazolamide; Ammonium Compounds; Blood Transfusion; Chemical and Drug Induced Liver Injury; Chloro

1964
Significance of hypokalaemia due to diuretics.
    The Netherlands journal of medicine, 1973, Volume: 16, Issue:1

    Topics: Amiloride; Arrhythmias, Cardiac; Chlorothiazide; Diuretics; Ethacrynic Acid; Extracellular Space; Fu

1973

Other Studies

15 other studies available for chlorothiazide and Hepatic Encephalopathy

ArticleYear
Production of impending hepatic coma by chlorothiazide and its prevention by antibiotics.
    The New England journal of medicine, 1958, 12-11, Volume: 259, Issue:24

    Topics: Acetazolamide; Anti-Bacterial Agents; Antibiotics, Antitubercular; Chlorothiazide; Dermatologic Agen

1958
[Complications of chlorothiazide therapy].
    Bulletin de la Societe des sciences medicales du Grand-Duche de Luxembourg, 1959, Volume: 96, Issue:1

    Topics: Acetazolamide; Chlorothiazide; Gout; Hepatic Encephalopathy; Purpura

1959
More on chlorthalidone.
    The New England journal of medicine, 1963, Feb-14, Volume: 268

    Topics: Chlorothiazide; Chlorthalidone; Hepatic Encephalopathy; Humans

1963
DRUGS RELATED TO THE EXACERBATION OR AMELIORATION OF HEPATIC COMA AND THEIR EFFECTS ON AMMONIA TOXICITY.
    Clinical science, 1963, Volume: 25

    Topics: Acetazolamide; Ammonia; Ammonium Chloride; Arginine; Chlorothiazide; Cortisone; Formaldehyde; Glutam

1963
THE METABOLISM OF THE VOLATILE AMINES. IV. THE ROLE OF DRUGS IN THE PATHOGENESIS OF HEPATIC ENCEPHALOPATHY.
    Canadian Medical Association journal, 1963, Oct-26, Volume: 89

    Topics: Amines; Ammonia; Animals; Blood Chemical Analysis; Brain Diseases; Chlorothiazide; Diuretics; Dogs;

1963
THE USE OF SPIRONOLACTONE AND LARGE DOSES OF STEROIDS IN THE TREATMENT OF ASCITES OF LIVER DISEASE.
    Southern medical journal, 1963, Volume: 56

    Topics: Adrenal Cortex Hormones; Ascites; Chlorothiazide; Diuresis; Hepatic Encephalopathy; Humans; Hyponatr

1963
[THE TREATMENT OF EDEMA WITH SULFONAMIDE DIURETICS].
    Vie medicale (Paris, France : 1920), 1964, Volume: 45

    Topics: Acetazolamide; Acidosis; Benzothiadiazines; Chlorothiazide; Chlorthalidone; Dehydration; Diuretics;

1964
THE MANAGEMENT OF HEPATIC COMA.
    The Medical clinics of North America, 1964, Volume: 48

    Topics: Acetazolamide; Adrenal Cortex Hormones; Alkalosis; Ammonia; Blood Transfusion; Chlorothiazide; Diet;

1964
BODY AND SERUM POTASSIUM IN LIVER DISEASE. II. RELATIONSHIPS TO ARTERIAL AMMONIA, BLOOD PH, AND HEPATIC COMA.
    Gastroenterology, 1965, Volume: 48

    Topics: Ammonia; Blood; Chlorothiazide; Hepatic Encephalopathy; Humans; Hydrogen-Ion Concentration; Hypokale

1965
Neuropsychiatric complications following chlorothiazide therapy in patients with hepatic cirrhosis: possible relation to hypokalaemia.
    Clinical science, 1959, Volume: 18

    Topics: Chlorothiazide; Hepatic Encephalopathy; Humans; Hypokalemia; Liver Cirrhosis; Potassium

1959
Silent acute pancreatitis with encephalomalacia mimicking hepatic coma.
    The American journal of gastroenterology, 1975, Volume: 63, Issue:1

    Topics: Acute Disease; Aged; Ascites; Autopsy; Brain; Chlorothiazide; Diagnosis, Differential; Encephalomala

1975
Complications of diuretic therapy in hepatic cirrhosis.
    Lancet (London, England), 1966, May-14, Volume: 1, Issue:7446

    Topics: Chlorothiazide; Diuretics; Ethacrynic Acid; Furosemide; Hepatic Encephalopathy; Humans; Hypokalemia;

1966
The complications of diuretic therapy in patients with cirrhosis.
    Annals of the New York Academy of Sciences, 1966, Nov-22, Volume: 139, Issue:2

    Topics: Alkalosis; Ascites; Blood Urea Nitrogen; Chlorothiazide; Ethacrynic Acid; Furosemide; Hepatic Enceph

1966
[Prevention and therapy of hepatic coma].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1970, Volume: 30, Issue:1

    Topics: Aged; Amides; Ammonia; Aspartic Acid; Chlorothiazide; Clopamide; Depression, Chemical; Diuretics; Fe

1970
Chlorothiazide-induced hepatic coma in pregnancy.
    American journal of obstetrics and gynecology, 1966, May-01, Volume: 95, Issue:1

    Topics: Adult; Chlorothiazide; Female; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Pre-Eclampsia; Pregn

1966