chlorothiazide has been researched along with Bronchopulmonary Dysplasia in 7 studies
Chlorothiazide: A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
thiazide : Heterocyclic compound with sulfur and nitrogen in the ring.
chlorothiazide : 4H-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position is substituted by chlorine and that at position 7 is substituted by a sulfonamide group. A diuretic, it is used for treatment of oedema and hypertension.
Bronchopulmonary Dysplasia: A chronic lung disease developed after OXYGEN INHALATION THERAPY or mechanical ventilation (VENTILATION, MECHANICAL) usually occurring in certain premature infants (INFANT, PREMATURE) or newborn infants with respiratory distress syndrome (RESPIRATORY DISTRESS SYNDROME, NEWBORN). Histologically, it is characterized by the unusual abnormalities of the bronchioles, such as METAPLASIA, decrease in alveolar number, and formation of CYSTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the effects of orally administered theophylline and diuretics (chlorothiazide and spironolactone) on pulmonary mechanics in 16 infants with bronchopulmonary dysplasia." | 9.06 | Oral theophylline and diuretics improve pulmonary mechanics in infants with bronchopulmonary dysplasia. ( Durand, DJ; Kao, LC; Nickerson, BG; Phillips, BL, 1987) |
| "We randomly selected 43 stable patients with oxygen-dependent bronchopulmonary dysplasia to receive either orally administered spironolactone and chlorothiazide or placebo." | 5.07 | Randomized trial of long-term diuretic therapy for infants with oxygen-dependent bronchopulmonary dysplasia. ( Birch, M; Durand, DJ; Kao, LC; McCrea, RC; Nickerson, BG; Powers, RJ, 1994) |
| "We studied the effects of orally administered theophylline and diuretics (chlorothiazide and spironolactone) on pulmonary mechanics in 16 infants with bronchopulmonary dysplasia." | 5.06 | Oral theophylline and diuretics improve pulmonary mechanics in infants with bronchopulmonary dysplasia. ( Durand, DJ; Kao, LC; Nickerson, BG; Phillips, BL, 1987) |
| "Furosemide was the most widely prescribed diuretic (1218 infants; 85%), although chlorothiazide had the longest median duration of use (21 days; 25th-75th percentile: 8-46 days)." | 1.39 | Variation in the use of diuretic therapy for infants with bronchopulmonary dysplasia. ( Reagan, PB; Slaughter, JL; Stenger, MR, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Slaughter, JL | 1 |
| Stenger, MR | 1 |
| Reagan, PB | 1 |
| Laughon, MM | 1 |
| Chantala, K | 1 |
| Aliaga, S | 1 |
| Herring, AH | 1 |
| Hornik, CP | 1 |
| Hughes, R | 1 |
| Clark, RH | 1 |
| Smith, PB | 1 |
| Bhandari, A | 1 |
| Chow, U | 1 |
| Hagadorn, JI | 1 |
| Kao, LC | 3 |
| Warburton, D | 1 |
| Cheng, MH | 1 |
| Cedeño, C | 1 |
| Platzker, AC | 1 |
| Keens, TG | 1 |
| Durand, DJ | 2 |
| McCrea, RC | 1 |
| Birch, M | 1 |
| Powers, RJ | 1 |
| Nickerson, BG | 2 |
| Noerr, B | 1 |
| Phillips, BL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Retrospective Chart Review Evaluating the Impact of Steroid, Diuretic, and Fluid Use Practice Trends in Extreme Premature Infants at Risk for Bronchopulmonary Dysplasia (BPD) at a Single Center Neonatal Intensive Care Unit[NCT04971694] | 175 participants (Anticipated) | Observational | 2021-09-08 | Recruiting | |||
| Determining the Effect of Spironolactone on Electrolyte Supplementation in Preterm Infants With Chronic Lung Disease[NCT01721655] | Phase 2/Phase 3 | 40 participants (Anticipated) | Interventional | 2012-10-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for chlorothiazide and Bronchopulmonary Dysplasia
| Article | Year |
|---|---|
Effect of oral diuretics on pulmonary mechanics in infants with chronic bronchopulmonary dysplasia: results of a double-blind crossover sequential trial.
Topics: Administration, Oral; Airway Resistance; Body Weight; Bronchopulmonary Dysplasia; Chlorothiazide; Cl | 1984 |
Randomized trial of long-term diuretic therapy for infants with oxygen-dependent bronchopulmonary dysplasia.
Topics: Analysis of Variance; Bronchopulmonary Dysplasia; Chlorothiazide; Double-Blind Method; Drug Therapy, | 1994 |
Oral theophylline and diuretics improve pulmonary mechanics in infants with bronchopulmonary dysplasia.
Topics: Administration, Oral; Bronchopulmonary Dysplasia; Chlorothiazide; Clinical Trials as Topic; Double-B | 1987 |
4 other studies available for chlorothiazide and Bronchopulmonary Dysplasia
| Article | Year |
|---|---|
Variation in the use of diuretic therapy for infants with bronchopulmonary dysplasia.
Topics: Bronchopulmonary Dysplasia; Chlorothiazide; Cohort Studies; Databases, Factual; Diuretics; Drug Admi | 2013 |
Diuretic exposure in premature infants from 1997 to 2011.
Topics: Acetazolamide; Amiloride; Bronchopulmonary Dysplasia; Chlorothiazide; Cohort Studies; Diazoxide; Diu | 2015 |
Variability in duration of outpatient diuretic therapy in bronchopulmonary dysplasia: a clinical experience.
Topics: Ambulatory Care; Bronchopulmonary Dysplasia; Chlorothiazide; Diuretics; Female; Humans; Infant, Newb | 2010 |
Chlorothiazide.
Topics: Bronchopulmonary Dysplasia; Calcium; Chlorothiazide; Humans; Infant, Newborn; Nephrocalcinosis | 1993 |