chlorothiazide has been researched along with Alkalosis in 19 studies
Chlorothiazide: A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
thiazide : Heterocyclic compound with sulfur and nitrogen in the ring.
chlorothiazide : 4H-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position is substituted by chlorine and that at position 7 is substituted by a sulfonamide group. A diuretic, it is used for treatment of oedema and hypertension.
Alkalosis: A pathological condition that removes acid or adds base to the body fluids.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlorothiazide treatment led to an alkalosis in brain." | 1.28 | Effect of magnesium depletion and potassium depletion and chlorothiazide on intracellular pH in the rat, studied by 31P NMR. ( Adam, WR; Craik, DJ; Kneen, M; Wellard, RM, 1989) |
| "Chlorothiazide has been shown to be almost ineffective as a diuretic agent per se." | 1.24 | SULFONAMYL DIURETICS--MECHANISM OF ACTION AND THERAPEUTIC USE. ( ROBERTS, KE, 1964) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SUZUKI, H | 1 |
| NIENHUIS, LI | 1 |
| MULMED, EI | 1 |
| KELLEY, JW | 1 |
| IWAKI, J | 1 |
| ROBERTS, KE | 1 |
| JONES, PN | 1 |
| CAPPS, RB | 1 |
| CANNON, PJ | 1 |
| HEINEMANN, HO | 1 |
| STASON, WB | 1 |
| LARAGH, JH | 1 |
| WOHLRABE, JC | 1 |
| PITTS, FN | 1 |
| BEYER, KH | 1 |
| BAER, JE | 1 |
| MICHAELSON, JK | 1 |
| RUSSO, HF | 1 |
| OLESEN, K | 3 |
| SANDOE, E | 3 |
| Adam, WR | 1 |
| Craik, DJ | 1 |
| Kneen, M | 1 |
| Wellard, RM | 1 |
| van Ypersele de Strihou, C | 1 |
| Chaimovitz, C | 1 |
| Levi, J | 1 |
| Better, OS | 1 |
| Oslander, L | 1 |
| Benderli, A | 1 |
| Iff, HW | 1 |
| Flenley, DC | 1 |
| Sherlock, S | 1 |
| Walker, JG | 1 |
| Senewiratne, B | 1 |
| Scott, A | 1 |
| Ardaillou, R | 1 |
| Fillastre, JP | 1 |
| Tuller, MA | 1 |
| Mehdi, F | 1 |
| Schifrin, BS | 1 |
| Spellacy, WN | 1 |
| Little, WA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Severe Impairment of Solute-Free Water Clearance in Patients With HIV Infection[NCT01869010] | 30 participants (Actual) | Observational | 2010-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for chlorothiazide and Alkalosis
| Article | Year |
|---|---|
HEPATIC COMA; TREATMENT EMPHASIZING MERIT OF PERITONEAL DIALYSIS.
Topics: Adrenal Cortex Hormones; Alkalosis; Ammonium Chloride; Anti-Bacterial Agents; Arginine; Chlorothiazi | 1963 |
2 trials available for chlorothiazide and Alkalosis
| Article | Year |
|---|---|
The ventilatory response to CO 2 after administration of frusemide in normal man.
Topics: Acetazolamide; Administration, Oral; Adult; Alkalosis; Arteries; Bicarbonates; Blood Gas Analysis; C | 1972 |
Proximal tubular acidification in man.
Topics: Acidosis, Renal Tubular; Adult; Alkalosis; Ammonium Chloride; Bicarbonates; Chlorides; Chlorothiazid | 1969 |
16 other studies available for chlorothiazide and Alkalosis
| Article | Year |
|---|---|
[EXPERIMENTAL AND CLINICAL STUDIES ON ELECTROLYTE METABOLISM IN POTASSIUM DEPLETION].
Topics: Alkalosis; Bicarbonates; Blood Chemical Analysis; Chlorothiazide; Desoxycorticosterone; Dogs; Electr | 1962 |
[A COMPARATIVE STUDY ON SULFONAMIDE DIURETICS].
Topics: Acetazolamide; Acidosis; Alkalosis; Blood Pressure; Cats; Chlorothiazide; Chlorthalidone; Diuretics; | 1963 |
SULFONAMYL DIURETICS--MECHANISM OF ACTION AND THERAPEUTIC USE.
Topics: Acetazolamide; Acidosis; Alkalosis; Ammonia; Benzothiadiazines; Blood Chemical Analysis; Chlorothiaz | 1964 |
THE MANAGEMENT OF HEPATIC COMA.
Topics: Acetazolamide; Adrenal Cortex Hormones; Alkalosis; Ammonia; Blood Transfusion; Chlorothiazide; Diet; | 1964 |
ETHACRYNIC ACID: EFFECTIVENESS AND MODE OF DIURETIC ACTION IN MAN.
Topics: Acetazolamide; Acidosis; Acidosis, Renal Tubular; Alkalosis; Ascites; Carbonic Anhydrase Inhibitors; | 1965 |
DELIRIUM AND COMPLEX ELECTROLYTE DISTURBANCE.
Topics: Alkalosis; Chlorothiazide; Delirium; Diet, Sodium-Restricted; Drug Therapy; Electrolytes; Hydrochlor | 1965 |
RENOTROPIC CHARACTERISTICS OF ETHACRYNIC ACID: A PHENOXYACETIC SALURETIC-DIURETIC AGENT.
Topics: Acidosis; Alkalosis; Chlorothiazide; Creatine; Creatinine; Diuretics; Dogs; Ethacrynic Acid; Hydroch | 1965 |
[Hypokalemis, hypochloremia and alkalosis in the long-term treatment of edematous heart insufficiency with benzothiadiazine diuretics. III. Effects of spirolactone].
Topics: Aldosterone; Alkalosis; Chlorothiazide; Diuretics; Edema; Heart Failure; Mineralocorticoid Receptor | 1962 |
[Hypokalemia, hypochloremia and alkalosis in the long-term treatment of edematous heart insufficiency with benzothiadiazine diuretics. I. Incidence and pathophysiology].
Topics: Alkalosis; Chlorothiazide; Edema; Heart Failure; Humans; Hypokalemia; Incidence; Potassium; Sodium C | 1962 |
[Hypokalemis, hypochloremia and alkalosis in the long-term treatment of edematous heart insufficiency with benzothiadiazine diuretics. II. The prophylactic value of potassium chloride].
Topics: Alkalosis; Chlorides; Chlorothiazide; Edema; Heart Failure; Humans; Potassium; Potassium Chloride; S | 1962 |
Effect of magnesium depletion and potassium depletion and chlorothiazide on intracellular pH in the rat, studied by 31P NMR.
Topics: Acid-Base Equilibrium; Alkalosis; Animals; Brain; Chlorothiazide; Heart; In Vitro Techniques; Magnes | 1989 |
Metabolic complications in the use of diuretics.
Topics: Alkalosis; Chlorothiazide; Diuretics; Hypercalcemia; Hyperglycemia; Hypokalemia; Metabolic Diseases; | 1972 |
Studies on the site of renal salt loss in a patient with Bartter's syndrome.
Topics: Adolescent; Adult; Alkalosis; Angiotensin II; Biological Transport, Active; Blood Pressure; Child; C | 1973 |
The complications of diuretic therapy in patients with cirrhosis.
Topics: Alkalosis; Ascites; Blood Urea Nitrogen; Chlorothiazide; Ethacrynic Acid; Furosemide; Hepatic Enceph | 1966 |
Compensatory hypoventilation and hypercapnia in primary metabolic alkalosis. Report of three cases.
Topics: Aged; Alkalosis; Bicarbonates; Chlorothiazide; Dehydration; Female; Humans; Hypercapnia; Hypokalemia | 1971 |
Maternal death associated with excessive ingestion of a chlorothiazide diuretic. Report of a case.
Topics: Adult; Alkalosis; Chlorothiazide; Edema; Female; Fetus; Humans; Hypokalemia; Hyponatremia; Pregnancy | 1969 |