chloroquine has been researched along with Wolman Disease in 2 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Wolman Disease: The severe infantile form of inherited lysosomal lipid storage diseases due to deficiency of acid lipase (STEROL ESTERASE). It is characterized by the accumulation of neutral lipids, particularly CHOLESTEROL ESTERS in leukocytes, fibroblasts, and hepatocytes. It is also known as Wolman's xanthomatosis and is an allelic variant of CHOLESTEROL ESTER STORAGE DISEASE.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bowden, KL | 1 |
| Bilbey, NJ | 1 |
| Bilawchuk, LM | 1 |
| Boadu, E | 1 |
| Sidhu, R | 1 |
| Ory, DS | 1 |
| Du, H | 1 |
| Chan, T | 1 |
| Francis, GA | 1 |
| Sparrow, CP | 1 |
| Pittman, RC | 1 |
2 other studies available for chloroquine and Wolman Disease
| Article | Year |
|---|---|
Lysosomal acid lipase deficiency impairs regulation of ABCA1 gene and formation of high density lipoproteins in cholesteryl ester storage disease.
Topics: ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Chloroquine; Cholesterol; Cho | 2011 |
Lysosomal acid lipase deficiency impairs regulation of ABCA1 gene and formation of high density lipoproteins in cholesteryl ester storage disease.
Topics: ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Chloroquine; Cholesterol; Cho | 2011 |
Lysosomal acid lipase deficiency impairs regulation of ABCA1 gene and formation of high density lipoproteins in cholesteryl ester storage disease.
Topics: ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Chloroquine; Cholesterol; Cho | 2011 |
Lysosomal acid lipase deficiency impairs regulation of ABCA1 gene and formation of high density lipoproteins in cholesteryl ester storage disease.
Topics: ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Chloroquine; Cholesterol; Cho | 2011 |
Cholesterol esters selectively taken up from high-density lipoproteins are hydrolyzed extralysosomally.
Topics: Adrenal Glands; Animals; Cells, Cultured; Chloroquine; Cholesterol Esters; Cytosol; Female; Fibrobla | 1990 |