chloroquine has been researched along with Wilms Tumor in 2 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Wilms Tumor: A malignant kidney tumor, caused by the uncontrolled multiplication of renal stem (blastemal), stromal (STROMAL CELLS), and epithelial (EPITHELIAL CELLS) elements. However, not all three are present in every case. Several genes or chromosomal areas have been associated with Wilms tumor which is usually found in childhood as a firm lump in a child's side or ABDOMEN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The role of autophagy in nephroblastoma is largely uninvestigated." | 1.48 | Autophagy Inhibition in Childhood Nephroblastoma and the Therapeutic Significance. ( Chen, X; Gu, WZ; Li, LJ; Li, MJ; Lv, Y; Wang, JH; Wang, YL; Yang, M; Yuan, LQ; Zhao, ZY; Zhou, D; Zhu, K, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, LJ | 1 |
| Wang, YL | 1 |
| Yuan, LQ | 1 |
| Gu, WZ | 1 |
| Zhu, K | 1 |
| Yang, M | 1 |
| Zhou, D | 1 |
| Lv, Y | 1 |
| Li, MJ | 1 |
| Zhao, ZY | 1 |
| Wang, JH | 1 |
| Chen, X | 1 |
| HART, CW | 1 |
| NAUNTON, RF | 1 |
2 other studies available for chloroquine and Wilms Tumor
| Article | Year |
|---|---|
Autophagy Inhibition in Childhood Nephroblastoma and the Therapeutic Significance.
Topics: Animals; Antimalarials; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Autopha | 2018 |
THE OTOTOXICITY OF CHLOROQUINE PHOSPHATE.
Topics: Abnormalities, Drug-Induced; Abortion, Induced; Ataxia; Cerebellar Diseases; Child; Chloroquine; Coc | 1964 |