Page last updated: 2024-10-24

chloroquine and Viremia

chloroquine has been researched along with Viremia in 5 studies

Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.

Viremia: The presence of viruses in the blood.

Research Excerpts

ExcerptRelevanceReference
"Dengue is a major public health problem in tropical and subtropical countries."2.76Kinetics of viremia and NS1 antigenemia are shaped by immune status and virus serotype in adults with dengue. ( Farrar, J; Minh, NN; Simmons, CP; Tran, HT; Tricou, V, 2011)
"The chloroquine treatment consisted of 600 mg at day 1, 600 mg at days 2 and 3, and 300 mg at days 4 and 5."2.73On chikungunya acute infection and chloroquine treatment. ( Boisson, V; Charrel, RN; De Lamballerie, X; Enault, S; Flahault, A; Le Grand, R; Reynier, JC; Roques, P, 2008)
"Chloroquine treatment significantly improved the survival of ZIKV-infected 1-day old suckling SCID Beige mice and reduced viremia in adult SCID Beige mice."1.51Chloroquine inhibits endosomal viral RNA release and autophagy-dependent viral replication and effectively prevents maternal to fetal transmission of Zika virus. ( Chen, L; Feng, L; Guo, W; Li, C; Li, P; Liu, X; Niu, X; Pan, W; Peng, J; Qu, L; Wang, Q; Wu, M; Yan, Q; Ye, X; Yi, C; Zhang, F; Zhang, S, 2019)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, S1
Yi, C1
Li, C1
Zhang, F1
Peng, J1
Wang, Q1
Liu, X1
Ye, X1
Li, P1
Wu, M1
Yan, Q1
Guo, W1
Niu, X1
Feng, L1
Pan, W1
Chen, L1
Qu, L1
Farias, KJ1
Machado, PR1
Muniz, JA1
Imbeloni, AA1
da Fonseca, BA1
De Lamballerie, X1
Boisson, V1
Reynier, JC1
Enault, S1
Charrel, RN1
Flahault, A1
Roques, P1
Le Grand, R1
Tricou, V2
Minh, NN2
Van, TP1
Lee, SJ1
Farrar, J2
Wills, B1
Tran, HT2
Simmons, CP2

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized Study to Evaluate the Safety and Antiviral Efficacy of Hydroxychloroquine in Patients With Newly Diagnosed COVID-19 Compared to Standard of Care Treatment[NCT04334967]Phase 413 participants (Actual)Interventional2020-03-30Suspended (stopped due to suspected unfavorable risk/benefit assessment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for chloroquine and Viremia

ArticleYear
On chikungunya acute infection and chloroquine treatment.
    Vector borne and zoonotic diseases (Larchmont, N.Y.), 2008, Volume: 8, Issue:6

    Topics: Alphavirus Infections; Animals; Antiviral Agents; Chikungunya virus; Chloroquine; Double-Blind Metho

2008
A randomized controlled trial of chloroquine for the treatment of dengue in Vietnamese adults.
    PLoS neglected tropical diseases, 2010, Aug-10, Volume: 4, Issue:8

    Topics: Adolescent; Adult; Antigens, Viral; Antiviral Agents; Chloroquine; Dengue; Double-Blind Method; Fema

2010
Kinetics of viremia and NS1 antigenemia are shaped by immune status and virus serotype in adults with dengue.
    PLoS neglected tropical diseases, 2011, Volume: 5, Issue:9

    Topics: Adolescent; Adult; Antigens, Viral; Antiviral Agents; Chloroquine; Dengue; Dengue Virus; Female; Hum

2011

Other Studies

2 other studies available for chloroquine and Viremia

ArticleYear
Chloroquine inhibits endosomal viral RNA release and autophagy-dependent viral replication and effectively prevents maternal to fetal transmission of Zika virus.
    Antiviral research, 2019, Volume: 169

    Topics: Animals; Antimalarials; Autophagy; Cell Line; Chlorocebus aethiops; Chloroquine; Disease Models, Ani

2019
Antiviral activity of chloroquine against dengue virus type 2 replication in Aotus monkeys.
    Viral immunology, 2015, Volume: 28, Issue:3

    Topics: Animals; Antiviral Agents; Aotidae; Chloroquine; Cytokines; Dengue; Dengue Virus; Disease Models, An

2015