chloroquine has been researched along with Viremia in 5 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Viremia: The presence of viruses in the blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dengue is a major public health problem in tropical and subtropical countries." | 2.76 | Kinetics of viremia and NS1 antigenemia are shaped by immune status and virus serotype in adults with dengue. ( Farrar, J; Minh, NN; Simmons, CP; Tran, HT; Tricou, V, 2011) |
| "The chloroquine treatment consisted of 600 mg at day 1, 600 mg at days 2 and 3, and 300 mg at days 4 and 5." | 2.73 | On chikungunya acute infection and chloroquine treatment. ( Boisson, V; Charrel, RN; De Lamballerie, X; Enault, S; Flahault, A; Le Grand, R; Reynier, JC; Roques, P, 2008) |
| "Chloroquine treatment significantly improved the survival of ZIKV-infected 1-day old suckling SCID Beige mice and reduced viremia in adult SCID Beige mice." | 1.51 | Chloroquine inhibits endosomal viral RNA release and autophagy-dependent viral replication and effectively prevents maternal to fetal transmission of Zika virus. ( Chen, L; Feng, L; Guo, W; Li, C; Li, P; Liu, X; Niu, X; Pan, W; Peng, J; Qu, L; Wang, Q; Wu, M; Yan, Q; Ye, X; Yi, C; Zhang, F; Zhang, S, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, S | 1 |
| Yi, C | 1 |
| Li, C | 1 |
| Zhang, F | 1 |
| Peng, J | 1 |
| Wang, Q | 1 |
| Liu, X | 1 |
| Ye, X | 1 |
| Li, P | 1 |
| Wu, M | 1 |
| Yan, Q | 1 |
| Guo, W | 1 |
| Niu, X | 1 |
| Feng, L | 1 |
| Pan, W | 1 |
| Chen, L | 1 |
| Qu, L | 1 |
| Farias, KJ | 1 |
| Machado, PR | 1 |
| Muniz, JA | 1 |
| Imbeloni, AA | 1 |
| da Fonseca, BA | 1 |
| De Lamballerie, X | 1 |
| Boisson, V | 1 |
| Reynier, JC | 1 |
| Enault, S | 1 |
| Charrel, RN | 1 |
| Flahault, A | 1 |
| Roques, P | 1 |
| Le Grand, R | 1 |
| Tricou, V | 2 |
| Minh, NN | 2 |
| Van, TP | 1 |
| Lee, SJ | 1 |
| Farrar, J | 2 |
| Wills, B | 1 |
| Tran, HT | 2 |
| Simmons, CP | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Study to Evaluate the Safety and Antiviral Efficacy of Hydroxychloroquine in Patients With Newly Diagnosed COVID-19 Compared to Standard of Care Treatment[NCT04334967] | Phase 4 | 13 participants (Actual) | Interventional | 2020-03-30 | Suspended (stopped due to suspected unfavorable risk/benefit assessment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for chloroquine and Viremia
| Article | Year |
|---|---|
On chikungunya acute infection and chloroquine treatment.
Topics: Alphavirus Infections; Animals; Antiviral Agents; Chikungunya virus; Chloroquine; Double-Blind Metho | 2008 |
A randomized controlled trial of chloroquine for the treatment of dengue in Vietnamese adults.
Topics: Adolescent; Adult; Antigens, Viral; Antiviral Agents; Chloroquine; Dengue; Double-Blind Method; Fema | 2010 |
Kinetics of viremia and NS1 antigenemia are shaped by immune status and virus serotype in adults with dengue.
Topics: Adolescent; Adult; Antigens, Viral; Antiviral Agents; Chloroquine; Dengue; Dengue Virus; Female; Hum | 2011 |
2 other studies available for chloroquine and Viremia
| Article | Year |
|---|---|
Chloroquine inhibits endosomal viral RNA release and autophagy-dependent viral replication and effectively prevents maternal to fetal transmission of Zika virus.
Topics: Animals; Antimalarials; Autophagy; Cell Line; Chlorocebus aethiops; Chloroquine; Disease Models, Ani | 2019 |
Antiviral activity of chloroquine against dengue virus type 2 replication in Aotus monkeys.
Topics: Animals; Antiviral Agents; Aotidae; Chloroquine; Cytokines; Dengue; Dengue Virus; Disease Models, An | 2015 |