chloroquine has been researched along with Uveal Neoplasms in 2 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Uveal Neoplasms: Tumors or cancer of the UVEA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These results suggest that YAP, MEK1/2, and lysosome function are necessary and critical targets for the therapy of GNAQ/11-driven melanoma, and identify trametinib plus hydroxychloroquine as a potential treatment strategy for metastatic uveal melanoma." | 3.96 | Chloroquine Sensitizes ( Blumer, KJ; Dale, KJ; Ghazi, PC; Kinsey, CG; McMahon, M; Odelberg, SJ; Onken, MD; Richards, JR; Sanchez, JMS; Scherzer, MT; Shin, D; Truong, A; Yoo, JH, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fei, X | 1 |
| Xie, X | 1 |
| Qin, R | 1 |
| Wang, A | 1 |
| Meng, X | 1 |
| Sun, F | 1 |
| Zhao, Y | 1 |
| Jiang, D | 1 |
| Chen, H | 1 |
| Huang, Q | 1 |
| Ji, X | 1 |
| Wang, Z | 1 |
| Truong, A | 1 |
| Yoo, JH | 1 |
| Scherzer, MT | 1 |
| Sanchez, JMS | 1 |
| Dale, KJ | 1 |
| Kinsey, CG | 1 |
| Richards, JR | 1 |
| Shin, D | 1 |
| Ghazi, PC | 1 |
| Onken, MD | 1 |
| Blumer, KJ | 1 |
| Odelberg, SJ | 1 |
| McMahon, M | 1 |
2 other studies available for chloroquine and Uveal Neoplasms
| Article | Year |
|---|---|
Proteomics analysis: inhibiting the expression of P62 protein by chloroquine combined with dacarbazine can reduce the malignant progression of uveal melanoma.
Topics: Animals; Cell Line, Tumor; Chloroquine; Dacarbazine; Humans; Melanoma; Mice; Mice, Nude; Proteomics; | 2022 |
Chloroquine Sensitizes
Topics: Animals; Antimalarials; Apoptosis; Cell Proliferation; Chloroquine; Drug Resistance, Neoplasm; Drug | 2020 |